Prominent role of DT-diaphorase as a cellular mechanism reducing chromium(VI) and reverting its mutagenicity.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMID 4005852)

Published in Cancer Res on July 01, 1985

Authors

S De Flora, A Morelli, C Basso, M Romano, D Serra, A De Flora

Articles citing this

NAD(P)H-dependent chromium (VI) reductase of Pseudomonas ambigua G-1: a Cr(V) intermediate is formed during the reduction of Cr(VI) to Cr(III). J Bacteriol (1992) 1.66

Vibrio harveyi nitroreductase is also a chromate reductase. Appl Environ Microbiol (2003) 1.02

Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium. Toxicol Sci (2010) 1.00

Effects of vitamins on chromium(VI)-induced damage. Environ Health Perspect (1991) 1.00

Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion. Proc Natl Acad Sci U S A (1989) 0.85

Emerging role of Nrf2 in adipocytes and adipose biology. Adv Nutr (2013) 0.85

Mechanism of flavin reduction and oxidation in the redox-sensing quinone reductase Lot6p from Saccharomyces cerevisiae. Biochemistry (2009) 0.84

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Crit Rev Toxicol (2013) 0.84

Metabolic reduction of chromium by alveolar macrophages and its relationships to cigarette smoke. J Clin Invest (1986) 0.84

Genetic predisposition for dermal problems in hexavalent chromium exposed population. J Nucleic Acids (2012) 0.80

Cytosolic activation of aromatic and heterocyclic amines. Inhibition by dicoumarol and enhancement in viral hepatitis B. Environ Health Perspect (1994) 0.80

Chromium(VI) stimulates Fyn to initiate innate immune gene induction in human airway epithelial cells. Chem Res Toxicol (2010) 0.78

In vivo effects of chromium. Environ Health Perspect (1994) 0.78

Articles by these authors

Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol (1998) 5.32

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J (2001) 5.23

Anomalous origin of coronary arteries and risk of sudden death: a study based on an autopsy population of congenital heart disease. Hum Pathol (1998) 4.23

Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood (2001) 3.84

Spectrum of clinicopathologic manifestations of arrhythmogenic right ventricular cardiomyopathy/dysplasia: a multicenter study. J Am Coll Cardiol (1997) 3.64

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2). Hum Mol Genet (2001) 3.12

Screening for hypertrophic cardiomyopathy in young athletes. N Engl J Med (1998) 2.91

Twenty four hour manometric recording of colonic motor activity in healthy man. Gut (1987) 2.75

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R. Proc Natl Acad Sci U S A (2002) 2.14

Clinical profile and long-term follow-up of 37 families with arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol (2000) 2.08

Up-regulation of IL-17 is associated with bioactive IL-8 expression in Helicobacter pylori-infected human gastric mucosa. J Immunol (2000) 2.08

Dissecting human T cell responses against Bordetella species. J Exp Med (1988) 2.07

Detection of animal viruses in coastal seawater and sediments. Appl Microbiol (1975) 2.01

Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element. J Biol Chem (2000) 2.00

Helicobacter pylori second-line rescue therapy with levofloxacin- and bismuth-containing quadruple therapy, after failure of standard triple or non-bismuth quadruple treatments. Aliment Pharmacol Ther (2015) 1.99

Histological findings of the internal inguinal ring in patients having indirect inguinal hernia. Hernia (2009) 1.98

Acute ischemic stroke and transient ischemic attack in the very old--risk factor profile and stroke subtype between patients older than 80 years and patients aged less than 80 years. Eur J Neurol (2007) 1.91

Mapping of murine Th1 helper T-Cell epitopes of mycolyl transferases Ag85A, Ag85B, and Ag85C from Mycobacterium tuberculosis. Infect Immun (2003) 1.91

Toxicity and mutagenicity of hexavalent chromium on Salmonella typhimurium. Appl Environ Microbiol (1977) 1.84

Proteinase-activated receptor 2 is an anti-inflammatory signal for colonic lamina propria lymphocytes in a mouse model of colitis. Proc Natl Acad Sci U S A (2001) 1.84

Natural trans-splicing in carnitine octanoyltransferase pre-mRNAs in rat liver. Proc Natl Acad Sci U S A (1998) 1.83

Arrhythmogenic right ventricular cardiomyopathy: diagnosis, prognosis, and treatment. Heart (2000) 1.77

Increased levels of soluble P-selectin in hypercholesterolemic patients. Circulation (1998) 1.73

Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted. J Virol (1998) 1.72

Prevention of cardiac surgery-associated acute kidney injury. Int J Artif Organs (2008) 1.69

Genotoxicity of chromium compounds. A review. Mutat Res (1990) 1.68

Preconditioning effects of levosimendan in coronary artery bypass grafting--a pilot study. Br J Anaesth (2006) 1.64

Sudden cardiac death in young people with apparently normal heart. Cardiovasc Res (2001) 1.61

Gastric acidity and gastroesophageal reflux patterns in patients with esophagitis. Gastroenterology (1992) 1.58

Familial effort polymorphic ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy map to chromosome 1q42-43. Am J Cardiol (2000) 1.57

The value of laparoscopy in the management of non-palpable testis. J Pediatr Urol (2010) 1.53

A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes. Biochem Biophys Res Commun (1993) 1.52

Increased soluble CD40 ligand levels in cystic fibrosis. J Thromb Haemost (2004) 1.51

Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: role of VacA and CagA. Infect Immun (1996) 1.51

Functional analysis of cis-acting elements regulating the alternative splicing of human CFTR exon 9. Hum Mol Genet (1999) 1.50

Human T cell clones define S1 subunit as the most immunogenic moiety of pertussis toxin and determine its epitope map. J Exp Med (1989) 1.49

Giardia lamblia infestation reveals underlying Whipple's disease in a patient with longstanding constipation. Am J Gastroenterol (1991) 1.48

Hepatitis B virus antigens in peripheral blood mononuclear cells during the course of viral infection. Clin Immunol Immunopathol (1994) 1.46

Reliability of the bright liver echo pattern in diagnosing steatosis in patients with cryptogenic and HCV-related hypertransaminasaemia. Clin Radiol (2009) 1.45

Selective endoscopic retrograde cholangiography and preoperative bile duct stone removal in patients scheduled for laparoscopic cholecystectomy: a prospective study. Am J Gastroenterol (1996) 1.45

Chronic inflammation in the pathogenesis of benign prostatic hyperplasia. Int J Androl (2009) 1.43

Effect of omeprazole and high doses of ranitidine on gastric acidity and gastroesophageal reflux in patients with moderate-severe esophagitis. Am J Gastroenterol (1990) 1.41

Sudden death in young people with apparently isolated mitral valve prolapse. G Ital Cardiol (1997) 1.41

Standardization and certification of reference antigens and antisera for 30 human adenovirus serotypes. Am J Epidemiol (1967) 1.41

[Intermittent priapism as a clinical feature of lumbar spinal stenosis]. Rev Neurol (2007) 1.40

Myocardial infarction in a patient with hypertrophic cardiomyopathy. N Engl J Med (2000) 1.39

Esophageal motor disorders in patients evaluated for dysphagia and/or noncardiac chest pain. Dysphagia (1992) 1.39

Sphincter-like motion following mechanical dilation of the internal inguinal ring during indirect inguinal hernia procedure. Hernia (2008) 1.39

Intragastric pH monitoring during antisecretory therapy in patient with gastrointestinal bleeding. Am J Gastroenterol (1989) 1.38

Beyond cold cardioplegia. Ann Thorac Surg (1992) 1.38

Determinants of female sexual dysfunction in type 2 diabetes. Int J Impot Res (2010) 1.38

Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach. Immunology (2001) 1.37

Colonic motility and gastric emptying in patients with irritable bowel syndrome. Effect of pretreatment with octylonium bromide. Dig Dis Sci (1986) 1.37

Colonic mass movements in idiopathic chronic constipation. Gut (1988) 1.36

Physical exercises in the treatment of adolescent idiopathic scoliosis: an updated systematic review. Physiother Theory Pract (2011) 1.35

Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J Clin Invest (1993) 1.35

Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34

Medical personnel respond. Physicians across the nation eager to volunteer. Mod Healthc (2001) 1.33

Exercises reduce the progression rate of adolescent idiopathic scoliosis: results of a comprehensive systematic review of the literature. Disabil Rehabil (2008) 1.33

Review of rehabilitation and orthopedic conservative approach to sagittal plane diseases during growth: hyperkyphosis, junctional kyphosis, and Scheuermann disease. Eur J Phys Rehabil Med (2009) 1.32

NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. Proc Natl Acad Sci U S A (2001) 1.31

IgA-driven T cell-mediated anti-bacterial immunity in man after live oral Ty 21a vaccine. J Immunol (1986) 1.30

The role of glial cells and apoptosis of enteric neurones in the neuropathology of intractable slow transit constipation. Gut (2005) 1.29

Human primary fibroblasts in vitro express a purinergic P2X7 receptor coupled to ion fluxes, microvesicle formation and IL-6 release. J Cell Sci (1999) 1.29

Synthesis of GDP-L-fucose by the human FX protein. J Biol Chem (1996) 1.28

Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut (1994) 1.27

Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27

Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies. Mol Ther (2004) 1.26

Cyclic GMP-dependent and -independent effects on the synthesis of the calcium messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate. J Biol Chem (1998) 1.25

Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats. Gastroenterology (1999) 1.24

Multiply deleted [E1, polymerase-, and pTP-] adenovirus vector persists despite deletion of the preterminal protein. J Gene Med (2000) 1.23

Enhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats. Gastroenterology (1999) 1.22

Dispersion of ventricular depolarization-repolarization: a noninvasive marker for risk stratification in arrhythmogenic right ventricular cardiomyopathy. Circulation (2001) 1.22

Expression of CD38 increases intracellular calcium concentration and reduces doubling time in HeLa and 3T3 cells. J Biol Chem (1998) 1.22

Bile acid concentrations in human and rat liver tissue and in hepatocyte nuclei. Gastroenterology (1997) 1.22

In vivo evidence of apoptosis in arrhythmogenic right ventricular cardiomyopathy. Am J Pathol (1998) 1.22

Progressive pneumoperitoneum in the management of giant incisional hernias: a study of 41 patients. Br J Surg (1990) 1.20

Pathophysiology of hemolysis in glucose-6-phosphate dehydrogenase deficiency. Semin Hematol (1990) 1.20

Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19

Modulation of erythrocyte Ca2+-ATPase by selective calpain cleavage of the calmodulin-binding domain. J Biol Chem (1989) 1.18

Evidence of a role for cyclic ADP-ribose in calcium signalling and neurotransmitter release in cultured astrocytes. J Neurochem (2001) 1.17

Maternal antibodies but not carotenoids in barn swallow eggs covary with embryo sex. J Evol Biol (2003) 1.17

Right bundle branch block, right precordial st-segment elevation, and sudden death in young people. Circulation (2001) 1.16

Induction of functional lipoxin A4 receptors in HL-60 cells. Blood (1993) 1.16

Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors. Hum Gene Ther (2003) 1.16

Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor alpha gene and their relationship to bone mass variation in postmenopausal Italian women. Hum Mol Genet (2000) 1.16

An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity. Proc Natl Acad Sci U S A (2001) 1.14

IL-1 beta converting enzyme is a target for nitric oxide-releasing aspirin: new insights in the antiinflammatory mechanism of nitric oxide-releasing nonsteroidal antiinflammatory drugs. J Immunol (2000) 1.14

Long-term efficacy after [E1-, polymerase-] adenovirus-mediated transfer of human acid-alpha-glucosidase gene into glycogen storage disease type II knockout mice. Hum Gene Ther (2001) 1.14

Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13

Mouse dendritic cells express the P2X7 purinergic receptor: characterization and possible participation in antigen presentation. J Immunol (1999) 1.13

NO-aspirin protects from T cell-mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines. Gastroenterology (2000) 1.13

The Schizosaccharomyces pombe protein Yab8p and a novel factor, Yip1p, share structural and functional similarity with the spinal muscular atrophy-associated proteins SMN and SIP1. Hum Mol Genet (2000) 1.13

Inhibition of angiogenesis-driven Kaposi's sarcoma tumor growth in nude mice by oral N-acetylcysteine. Cancer Res (2001) 1.13

Nutritional state and energy balance in cirrhotic patients with or without hypermetabolism. Multicentre prospective study by the 'Nutritional Problems in Gastroenterology' Section of the Italian Society of Gastroenterology (SIGE). Dig Liver Dis (2005) 1.13

A self-restricted CD38-connexin 43 cross-talk affects NAD+ and cyclic ADP-ribose metabolism and regulates intracellular calcium in 3T3 fibroblasts. J Biol Chem (2001) 1.12

Effects of selective inhibitors on cyclic nucleotide phosphodiesterases of rabbit aorta. Biochem Pharmacol (1989) 1.11

The role of the thiol N-acetylcysteine in the prevention of tumor invasion and angiogenesis. Int J Biol Markers (2000) 1.11

Apple polyphenol extracts prevent damage to human gastric epithelial cells in vitro and to rat gastric mucosa in vivo. Gut (2005) 1.11