Published in J Exp Med on November 01, 1965
Immunoglobulin spots on the surface of rabbit lymphocytes. J Exp Med (1970) 8.87
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc Natl Acad Sci U S A (1976) 5.81
Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers. J Exp Med (1968) 5.72
An immunofluorescence procedure for the detection of intracellular immunoglobulins. Clin Exp Immunol (1969) 4.77
Organization of immunoglobulin heavy chain genes and allelic deletion model. Proc Natl Acad Sci U S A (1978) 3.95
Rate of somatic mutation in immunoglobulin production by mouse myeloma cells. Proc Natl Acad Sci U S A (1971) 3.83
Rabbit lymphoid cells differentiated with respect to alpha-, gamma-, and mu- heavy polypeptide chains and to allotypic markers Aa1 and Aa2. J Exp Med (1966) 2.95
Idiotypy of rabbit antibodies. II. Comparison of idiotypy of various kinds of antibodies formed in the same rabbits against Salmonella typhi. J Exp Med (1969) 2.90
Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription. J Exp Med (1991) 2.88
Studies on rabbit lymphocytes in vitro. V. The induction of blast transformation with sheep antisera to rabbit IgG subunits. J Exp Med (1967) 2.65
Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching. EMBO J (1986) 2.62
Cellular differentiation of the immune system of mice. I. Separate splenic antigen-sensitive units for different types of anti-sheep antibody-forming cells. J Exp Med (1968) 2.51
Studies on rabbit lymphocytes in vitro. VI. The induction of blast transformation with sheep antisera to rabbit IgA and IgM. J Exp Med (1967) 2.38
One cell-one immunoglobulin. Origin of limited heterogeneity of myeloma proteins. Biochem J (1970) 2.36
Active suppression of immunoglobulin allotype synthesis. II. Transfer of suppressing factor with spleen cells. J Exp Med (1972) 2.34
Activation of V kappa gene rearrangement in pre-B cells follows the expression of membrane-bound immunoglobulin heavy chains. EMBO J (1987) 2.31
Autoreactive B cells in the marginal zone that express dual receptors. J Exp Med (2002) 2.16
Antibody production studied by means of the localized haemolysis in gel (LHG) assay. 3. Mouse cells producing five different classes of antibody. Immunology (1969) 2.04
Cmu gene rearrangement of mouse immunoglobulin genes in normal B cells occurs on both the expressed and nonexpressed chromosomes. Proc Natl Acad Sci U S A (1981) 1.82
Mechanisms and consequences of widespread random monoallelic expression. Nat Rev Genet (2012) 1.81
Cloning immunoglobulin gamma 2b chain gene of mouse: characterization and partial sequence determination. Proc Natl Acad Sci U S A (1979) 1.80
Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains. J Exp Med (1988) 1.78
Specificity of the antibodies produced by single cells following immunization with antigens bearing two types of antigenic determinants. J Exp Med (1967) 1.75
Specific antibody within lymphoid germinal center cells of mice after primary immunization with horseradish peroxidase: a light and electron microscopic study. J Exp Med (1970) 1.75
Initial genomics of the human nucleolus. PLoS Genet (2010) 1.71
Differential activity of allelic gamma-globulin genes in antibody-producing cells. Proc Natl Acad Sci U S A (1965) 1.62
Inherited polymorphism of the human T-cell antigen receptor detected by a monoclonal antibody. Proc Natl Acad Sci U S A (1986) 1.61
Immunological memory in mice. I. Physical separation and partial characterization of memory cells for different immunoglobulin classes from each other and from antibody-producing cells. J Exp Med (1970) 1.57
Restriction of the capacity to respond to two antigens by single precursors of antibody-producing cells in culture. J Exp Med (1969) 1.55
RNA splicing mutation in an aberrantly rearranged immunoglobulin lambda I gene. Proc Natl Acad Sci U S A (1981) 1.55
Antigen receptor allelic exclusion: an update and reappraisal. J Immunol (2010) 1.54
Immunoglobulin determinants on the lymphocytes of normal rabbits. 3. As4 and As6 determinants on individual lymphocytes and the concept of allelic exclusion. Immunology (1971) 1.54
Immunoglobulin isoantigens (allotypes) in the mouse. II. Allotypic analysis of three gammaG2-myeloma proteins from (NZB x BALB/c)F1 hybrids and of normal gammaG2-globulins. J Exp Med (1966) 1.51
Receptor selection in B and T lymphocytes. Annu Rev Immunol (2000) 1.49
Membrane-associated immunoglobulin of rabbit peripheral blood lymphocytes: allelic exclusion at the b locus. Proc Natl Acad Sci U S A (1971) 1.45
Immunoglobulins and immunocytes. Bacteriol Rev (1969) 1.45
Specificity of the immune response to the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl groups. Ligand binding and fluorescence properties of cross-reacting antibodies. J Exp Med (1969) 1.44
Murine lambda gene rearrangements: the stochastic model prevails over the ordered model. EMBO J (1990) 1.44
Immune responses in spleen colonies. II. Clonal assortment of 19S- and 7S-producing cells in mice reacting against two antigens. Immunology (1966) 1.41
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T-cell gamma gene is allelically but not isotypically excluded and is not required in known functional T-cell subsets. Proc Natl Acad Sci U S A (1987) 1.31
A theory of allelic and isotypic exclusion for immunoglobulin genes. Proc Natl Acad Sci U S A (1982) 1.31
Autosomal monoallelic expression in the mouse. Genome Biol (2012) 1.30
Cellular differentiation of the immune system of mice. II. Frequency of unipotent splenic antigen-sensitive units after immunization with sheep erythrocytes. J Exp Med (1969) 1.26
The relationship between antibody formation and deoxyribonucleic acid (DNA) synthesis in mouse spleen during primary and secondary response to sheep erythrocytes (SRC). Immunology (1972) 1.25
Restriction of gene expression in B lymphocytes and their progeny. I. Commitment to immunoglobulin allotype. J Exp Med (1974) 1.24
Plasmacytomas with more than one immunoglobulin kappa mRNA: implications for allelic exclusion. Proc Natl Acad Sci U S A (1981) 1.24
Genome-wide assessment of imprinted expression in human cells. Genome Biol (2011) 1.22
Antibody production in mice. I. The analysis of immunological memory. Immunology (1969) 1.21
Allelic inclusion in the pre-B-cell line 18-81. Proc Natl Acad Sci U S A (1984) 1.21
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Random monoallelic gene expression increases upon embryonic stem cell differentiation. Dev Cell (2014) 1.17
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Deletion of b5 immunoglobulin-bearing lymphocytes in allotype-suppressed rabbits. J Exp Med (1973) 1.16
The production of immunoglobulins by human peripheral blood lymphocytes in vitro. Clin Exp Immunol (1967) 1.14
Studies on rabbit lymphocytes in vitro. 8. The relationship between heterozygosity and homozygosity of lymphocyte donor and per cent blast transformation induced by antiallotype sera. J Exp Med (1968) 1.14
Preferential expression of variable region heavy chain gene segments by predominant 2,4-dinitrophenyl-specific BALB/c neonatal antibody clonotypes. Proc Natl Acad Sci U S A (1986) 1.13
kappa+lambda+ dual receptor B cells are present in the human peripheral repertoire. J Exp Med (1995) 1.11
Studies on rabbit lymphocytes in vitro. IX. The suppression of antiallotype-induced blast transformation in lymphocyte cultures from allotypically suppressed donors. J Exp Med (1968) 1.09
Immunoglobulin G and free kapa-chain synthesis in different clones of a hybrid cell line. Proc Natl Acad Sci U S A (1971) 1.07
Stochastic gene expression in mammals: lessons from olfaction. Trends Cell Biol (2013) 1.06
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Chromatin signature of widespread monoallelic expression. Elife (2013) 1.03
B cell receptor editing in tolerance and autoimmunity. Ann N Y Acad Sci (2011) 1.01
Replica analysis of the class of antibodies produced by single cells. Clin Exp Immunol (1970) 1.00
Myeloma with multiple rearranged immunoglobulin kappa genes: only one kappa gene codes for kappa chains. Nucleic Acids Res (1980) 1.00
The proportion of two b locus allotypic determinants in rabbit antisera raised against pneumococcal polysaccharide SSS 3 antigen. Immunology (1969) 0.99
Molecular requirements for the mu-induced light chain gene rearrangement in pre-B cells. EMBO J (1991) 0.98
Biallelic germline transcription at the kappa immunoglobulin locus. J Exp Med (2003) 0.98
Two distinct T-cell receptor alpha-chain transcripts in a rabbit T-cell line: implications for allelic exclusion in T cells. Proc Natl Acad Sci U S A (1986) 0.98
Transformation of rabbit lymphocytes by anti-allotype serum: ultrastructure of transformed cells and suppression of responding cells by foetal exposure to anti-allotype serum. Immunology (1969) 0.97
An epigenetic state associated with areas of gene duplication. Genome Res (2006) 0.95
Recombinant rabbit secretory immunoglobulin molecules: alpha chains with maternal (paternal) variable-region allotypes and paternal (maternal) constant-region allotypes. Proc Natl Acad Sci U S A (1974) 0.94
Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors. Mol Cell Biol (1992) 0.93
Rearrangement and expression of endogenous immunoglobulin genes occur in many murine B cells expressing transgenic membrane IgM. Proc Natl Acad Sci U S A (1988) 0.91
Epigenetic control of recombination in the immune system. Semin Immunol (2010) 0.91
Extended duration of DH-JH rearrangement in immunoglobulin heavy chain transgenic mice: implications for regulation of allelic exclusion. J Exp Med (1999) 0.91
Immunocytochemical localization of the ovine immunoglobulins IgA, IgG1, IgG1-A and IgG2: effect of gastro-intestinal parasitism in the sheep. Clin Exp Immunol (1971) 0.89
Pro-B cells sense productive immunoglobulin heavy chain rearrangement irrespective of polypeptide production. Proc Natl Acad Sci U S A (2011) 0.89
Allotype suppression of the responsiveness of adoptively transferred adult spleen cells induced by affinity prepared anti-allotype antibody. Immunology (1981) 0.88
A single pre-B cell can give rise to antigen-specific B cells that utilize distinct immunoglobulin gene rearrangements. J Exp Med (1990) 0.88
Simultaneous expression of mu- and gamma-chain mRNA in cloned murine B-lymphoma cell lines. EMBO J (1983) 0.88
Global RNA sequencing reveals that genotype-dependent allele-specific expression contributes to differential expression in rice F1 hybrids. BMC Plant Biol (2013) 0.88
Allelic exclusion of immunoglobulin expression is not caused by somatic segregation. Proc Natl Acad Sci U S A (1982) 0.88
Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed. J Cell Biol (2007) 0.88
Differential accessibility at the kappa chain locus plays a role in allelic exclusion. EMBO J (2002) 0.87
TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes. J Immunol (2009) 0.87
Pre-B and B cells in rabbits. Ontogeny and allelic exclusion of kappa light chain genes. J Exp Med (1978) 0.86
Independent Roles of Switching and Hypermutation in the Development and Persistence of B Lymphocyte Memory. Immunity (2016) 0.85
Regulation of natural antiallotype antibody responses by idiotype network-induced auto-antiidiotypic antibodies. J Exp Med (1983) 0.85
Asynchronous replication and autosome-pair non-equivalence in human embryonic stem cells. PLoS One (2009) 0.85
Random and non-random monoallelic expression. Neuropsychopharmacology (2012) 0.84
Regulation of the immune system by synthetic polynucleotides. V. Effect on cell-associated immunoglobulin receptors and immunological memory. J Exp Med (1972) 0.83
The role of I-J and Igh determinants on F1-derived suppressor factor in controlling restriction specificity. J Exp Med (1983) 0.83
Epigenetic regulation of monoallelic rearrangement (allelic exclusion) of antigen receptor genes. Front Immunol (2014) 0.82
Immunoglobulin (Ig) mu, kappa transgenic mice express transgenic idiotype on endogenously rearranged IgM and IgA molecules by secretion of chimeric molecules. J Exp Med (1992) 0.82
Kappa and lambda receptor sites on single lymphocytes. Clin Exp Immunol (1971) 0.81
Chromatin Signature Identifies Monoallelic Gene Expression Across Mammalian Cell Types. G3 (Bethesda) (2015) 0.81
Localization of antigen in tissue cells; improvements in a method for the detection of antigen by means of fluorescent antibody. J Exp Med (1950) 43.56
Studies on antibody production. I. A method for the histochemical demonstration of specific antibody and its application to a study of the hyperimmune rabbit. J Exp Med (1955) 16.36
Reduction of gamma-globulins. Arch Biochem Biophys (1962) 13.22
Fluorescent antibody methods. Gen Cytochem Methods (1958) 5.56
Cellular sites of formation of gamma globulin. J Exp Med (1957) 4.68
THE CELLULAR ORIGIN OF HUMAN IMMUNOGLOBULINS (GAMMA-2, GAMMA-1M, GAMMA-1A). J Exp Med (1963) 4.48
A notation for allotypy. Nature (1962) 3.88
Allotypy of rabbit serum proteins. I. Immuno-chemical analysis leading to the individualization of seven main allotypes. J Exp Med (1960) 3.59
Genetic characters of human gamma-globulins in myeloma proteins. J Exp Med (1962) 3.26
Effect of maternal isoantibodies on the quantitative expression of two allelic genes controlling gamma-globulin allotypic specificities. Nature (1962) 3.09
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A MODEL FOR THE 7S ANTIBODY MOLECULE. Proc Natl Acad Sci U S A (1964) 2.49
THE MOLECULAR BASIS OF ANTIBODY FORMATION. Proc Natl Acad Sci U S A (1960) 2.25
GROSS CONFORMATION OF RABBIT 7 S GAMMA-IMMUNOGLOBULIN AND ITS PAPAIN-CLEAVED FRAGMENTS. J Biol Chem (1965) 2.21
A RELATIONSHIP BETWEEN THE H CHAIN GROUPS OF 7S GAMMA-GLOBULIN AND THE GM SYSTEM. Nature (1964) 2.12
DISORDERS IN THE DIFFERENTIATON OF PROTEIN SECRETION IN NEOPLASTIC PLASMA CELLS. J Mol Biol (1964) 2.09
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THE LOCALIZATION OF ALBUMIN AND FIBRINOGEN IN HUMAN LIVER CELLS. J Cell Biol (1964) 1.85
POLYPEPTIDE CHAINS OF HUMAN GAMMA-GLOBULIN: CELLULAR LOCALIZATION BY FLUORESCENT ANTIBODY. Science (1964) 1.72
IDENTIFICATION IN HUMAN LYMPHOID TISSUES OF CELLS THAT PRODUCE GROUP 1 OR GROUP 2 GAMMA-GLOBULINS. Immunology (1964) 1.71
LOCALIZATION BY IMMUNOFLUORESCENCE OF GAMMA-GLOBULIN ALLOTYPES IN LYMPH NODE CELLS OF HOMOZYGOUS AND HETEROZYGOUS RABBITS. Immunology (1964) 1.70
A STUDY OF RABBIT GAMMA-GLOBULIN ALLOTYPY BY MEANS OF HETEROIMMUNIZATIONS. J Exp Med (1964) 1.68
STUDIES ON THE RELATIONSHIP OF ALLOTYPIC SPECIFICITIES TO ANTIBODY SPECIFICITIES IN THE RABBIT. J Exp Med (1963) 1.67
HERITABLE VARIATION IN BENCE JONES PROTEIN STRUCTURE IN AN INBRED STRAIN OF MICE. J Mol Biol (1964) 1.54
Studies of mercaptoethanol-dissociated normal human 19 S gamma-globulin and pathologic macroglobulins from patients with macroglobulinemia. J Immunol (1961) 1.39
SYMMETRICAL DISTRIBUTION OF GENETIC MARKERS IN INDIVIDUAL RABBIT GAMMA-GLOBULIN MOLECULES. Immunochemistry (1964) 1.17
Immunochemical study of rabbit gamma-globulin allotypes. J Immunol (1963) 1.08
Cytochemical studies and quantitative television fluorescence and absorption spectroscopy. Ann N Y Acad Sci (1962) 0.97
Immunoglobulin spots on the surface of rabbit lymphocytes. J Exp Med (1970) 8.87
The dynamic state of the lymphocyte membrane. Factors affecting the distribution and turnover of surface immunoglobulins. Eur J Immunol (1972) 7.05
Immunoglobulin D as a lymphocyte receptor. J Exp Med (1973) 4.62
Immunoglobulin allotypes of experimental animals. Prog Allergy (1967) 3.57
Delayed hypersensitivity in the guinea-pig to a protein-hapten conjugate and its relationship to in vitro transformation of lymph node, spleen, thymus and peripheral blood lymphocytes. Immunology (1967) 3.33
Immunoglobulins as cell receptors. Ann N Y Acad Sci (1971) 3.25
Lymphocytes in human immunodeficiency states: a study of membrane-associated immunoglobulins. Eur J Immunol (1971) 2.86
Immunological analysis of rabbit anti-antibody systems. J Exp Med (1968) 2.84
Role of early region 3 (E3) in pathogenesis of adenovirus disease. Proc Natl Acad Sci U S A (1989) 2.74
Role of CD8+ T cells in murine experimental allergic encephalomyelitis. Science (1992) 2.57
Studies on rabbit lymphocytes in vitro. II. Induction of blast transformation with antisera to six IgG allotypes and summation with mixtures of antisera to different allotypes. J Exp Med (1965) 2.25
Specific binding of alloantigens to T cells activated in the mixed lymphocyte reaction. J Exp Med (1976) 2.04
Demonstration of the exposure of new antigenic determinants following antigen-antibody combination. Nature (1965) 2.04
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Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing V beta 8 TCR: a role of the Qa-1 molecule. Immunity (1995) 1.72
An allotypic determinant specific to rabbit macroglobulin. Nature (1965) 1.70
Rheumatoid factor in serum of individuals exposed to asbestos. Ann N Y Acad Sci (1965) 1.65
Blocking and redistribution ("capping") of antigen receptors on T and B lymphocytes by anti-immunoglobulin antibody. J Exp Med (1973) 1.63
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Variant strain of rabbits lacking immunoglobulin kappa polypeptide chain. Nature (1977) 1.43
Membrane phenotype of murine effector and suppressor T cells involved in delayed hypersensitivity and protective immunity to herpes simplex virus. Cell Immunol (1983) 1.42
Physiology of IgD. IV. Enhancement of antibody production in mice bearing IgD-secreting plasmacytomas. J Exp Med (1984) 1.37
Tolerance and immunity in mice infected with herpes simplex virus: simultaneous induction of protective immunity and tolerance to delayed-type hypersensitivity. Immunology (1981) 1.36
Ultrastructure of cells present in lymph nodes during the development of contact sensitivity. Int Arch Allergy Appl Immunol (1966) 1.34
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The proportion of two b locus allotypic determinants in rabbit antisera raised against pneumococcal polysaccharide SSS 3 antigen. Immunology (1969) 0.99
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Lpl--allotypic determinant of rabbit beta-lipoprotein. Nature (1968) 0.93
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Role of infective, immunological, and chronic irritative factors in the development of silicosis. Br J Ind Med (1982) 0.89
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Mutation affecting the expression of immunoglobulin variable regions in the rabbit. Proc Natl Acad Sci U S A (1986) 0.88
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