Published in J Biol Chem on April 10, 1970
Kinetics of the attachment of intrinsic factor-bound cobamides to ileal receptors. J Clin Invest (1974) 0.94
Identification of the substrate radical intermediate derived from ethanolamine during catalysis by ethanolamine ammonia-lyase. Biochemistry (2008) 0.92
5'-Peroxyadenosine and 5'-peroxyadenosylcobalamin as intermediates in the aerobic photolysis of adenosylcobalamin. Biochemistry (2007) 0.89
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest (1973) 17.56
Oxygen-dependent microbial killing by phagocytes (first of two parts). N Engl J Med (1978) 11.45
Oxygen-dependent microbial killing by phagocytes (second of two parts). N Engl J Med (1978) 4.31
Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest (1994) 4.28
Defective superoxide production by granulocytes from patients with chronic granulomatous disease. N Engl J Med (1974) 4.21
The respiratory burst of phagocytes. J Clin Invest (1984) 3.86
Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes. J Clin Invest (1974) 3.78
Oxidants from phagocytes: agents of defense and destruction. Blood (1984) 3.20
Subcellular localization of the large subunit of Mo1 (Mo1 alpha; formerly gp 110), a surface glycoprotein associated with neutrophil adhesion. J Clin Invest (1984) 3.01
The origin of the chemiluminescence of phagocytosing granulocytes. J Clin Invest (1976) 2.92
Biological defense mechanisms. Evidence for the participation of superoxide in bacterial killing by xanthine oxidase. J Lab Clin Med (1975) 2.65
The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst. J Clin Invest (1976) 2.43
Subcellular localization of the superoxide-forming enzyme in human neutrophils. J Clin Invest (1979) 2.33
An inherited abnormality of neutrophil adhesion. Its genetic transmission and its association with a missing protein. N Engl J Med (1980) 2.32
The respiratory burst oxidase. J Biol Chem (1994) 2.29
Evidence for hydroxyl radical production by human neutrophils. J Clin Invest (1977) 2.15
Defect in pyridine nucleotide dependent superoxide production by a particulate fraction from the cranulocytes of patients with chronic granulomatous disease. N Engl J Med (1975) 2.05
Aromatization of cyclohexanecarboxylic acid. J Biol Chem (1966) 2.04
Severe recurrent bacterial infections associated with defective adherence and chemotaxis in two patients with neutrophils deficient in a cell-associated glycoprotein. J Pediatr (1982) 2.03
Measurement of O2- production by human neutrophils. The preparation and assay of NADPH oxidase-containing particles from human neutrophils. Methods Enzymol (1984) 1.97
Neutrophils and host defense. Ann Intern Med (1988) 1.92
The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases. J Biol Chem (1994) 1.90
Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils. Blood (1999) 1.88
Effects of anaerobiosis and inhibitors on O2-production by human granulocytes. Blood (1975) 1.85
Termination of the respiratory burst in human neutrophils. J Clin Invest (1978) 1.80
Cloning and expression of a human muscle phosphofructokinase cDNA. Gene (1989) 1.66
Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification. Proc Natl Acad Sci U S A (1996) 1.66
Pyridine nucleotide-dependent superoxide production by a cell-free system from human granulocytes. J Clin Invest (1975) 1.57
Activation of p38 in stimulated human neutrophils: phosphorylation of the oxidase component p47phox by p38 and ERK but not by JNK. Arch Biochem Biophys (1996) 1.54
Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinase. J Biol Chem (1996) 1.48
Cell acidification in apoptosis: granulocyte colony-stimulating factor delays programmed cell death in neutrophils by up-regulating the vacuolar H(+)-ATPase. Proc Natl Acad Sci U S A (1995) 1.48
Chronic granulomatous disease. Adv Hum Genet (1987) 1.48
Loss of function of cytochrome c in Jurkat cells undergoing fas-mediated apoptosis. J Biol Chem (1996) 1.47
Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit. J Cell Biol (1995) 1.46
A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease. J Biol Chem (1986) 1.45
Effects of oxygen tension and pH on the respiratory burst of human neutrophils. Blood (1979) 1.42
Superoxide-forming enzyme from human neutrophils: evidence for a flavin requirement. Blood (1977) 1.42
Endogenous protein phosphorylation by resting and activated human neutrophils. Blood (1983) 1.41
The O2(-) -forming oxidase responsible for the respiratory burst in human neutrophils. Properties of the solubilized enzyme. J Biol Chem (1979) 1.36
The phosphorylation targets of p47phox, a subunit of the respiratory burst oxidase. Functions of the individual target serines as evaluated by site-directed mutagenesis. J Clin Invest (1995) 1.34
Studies on the interaction between GP-18-0-deficient neutrophils and vascular endothelium. Blood (1982) 1.34
Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis. J Biol Chem (1997) 1.33
Cloning, sequencing, and expression of the genes encoding the adenosylcobalamin-dependent ethanolamine ammonia-lyase of Salmonella typhimurium. J Biol Chem (1990) 1.31
The O2--producing enzyme of human neutrophils. Further properties. J Biol Chem (1981) 1.31
Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity. J Biol Chem (1998) 1.30
Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304. J Biol Chem (1998) 1.29
Fluoride-mediated activation of the respiratory burst in human neutrophils. A reversible process. J Clin Invest (1979) 1.23
Activation of the respiratory burst oxidase in a fully soluble system from human neutrophils. J Biol Chem (1987) 1.22
The oxidative killing mechanisms of the neutrophil. Prog Clin Immunol (1977) 1.21
The respiratory burst oxidase of human neutrophils. Further studies of the purified enzyme. J Biol Chem (1986) 1.14
Manganese-dependent NADPH oxidation by granulocyte particles. The role of superoxide and the nonphysiological nature of the manganese requirement. J Clin Invest (1976) 1.14
JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase. J Biol Chem (2001) 1.14
Neutrophil-mediated antibody-dependent killing of herpes-simplex-virus-infected cells. Blood (1979) 1.14
Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils. J Clin Invest (1991) 1.13
Arrangement of the respiratory burst oxidase in the plasma membrane of the neutrophil. J Clin Invest (1981) 1.10
Postoperative massive liver necrosis. A clinical and pathological study. N Engl J Med (1967) 1.07
Stimulation of mitochondrial adenosine diphosphate uptake by thyroid hormones. Proc Natl Acad Sci U S A (1973) 1.07
The cytosolic components of the respiratory burst oxidase exist as a M(r) approximately 240,000 complex that acquires a membrane-binding site during activation of the oxidase in a cell-free system. J Biol Chem (1992) 1.07
Respiratory burst oxidase from human neutrophils: purification and some properties. Proc Natl Acad Sci U S A (1985) 1.06
Overexpression, purification, and some properties of the AdoCbl-dependent ethanolamine ammonia-lyase from Salmonella typhimurium. Arch Biochem Biophys (1992) 1.04
Unique characteristics of superoxide production by human eosinophils in eosinophilic states. Inflammation (1979) 1.03
Evidence for production of oxidizing radicals by the particulate O-2-forming system from human neutrophils. Blood (1979) 1.01
Kinase-dependent activation of the leukocyte NADPH oxidase in a cell-free system. Phosphorylation of membranes and p47(PHOX) during oxidase activation. J Biol Chem (1997) 1.01
The killing of pathogens by phagocytes. Annu Rev Med (1981) 1.00
Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558. Proc Natl Acad Sci U S A (2001) 0.96
The mechanism of adenosylcobalamin-dependent reactions. CRC Crit Rev Biochem (1979) 0.96
The cytosolic subunit p67phox contains an NADPH-binding site that participates in catalysis by the leukocyte NADPH oxidase. J Clin Invest (1996) 0.95
The mechanism of action of ethanolamine ammonia-lyase, a B-12-dependent enzyme. The participation of paramagnetic species in the catalytic deamination of 2-aminopropanol. J Biol Chem (1974) 0.95
O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA. Proc Natl Acad Sci U S A (1992) 0.95
The p67-phox cytosolic peptide of the respiratory burst oxidase from human neutrophils. Functional aspects. J Clin Invest (1990) 0.94
Solubilization of the O2(-)-forming activity responsible for the respiratory burst in human neutrophils. J Biol Chem (1978) 0.94
The translocation of respiratory burst oxidase components from cytosol to plasma membrane is regulated by guanine nucleotides and diacylglycerol. J Biol Chem (1992) 0.94
Kinetics of the attachment of intrinsic factor-bound cobamides to ileal receptors. J Clin Invest (1974) 0.94
Diminished activity of a chemotactic inhibitor in synovial fluids from patients with familial Mediterranean fever. Blood (1984) 0.94
Alternative splicing of the transcript encoding the human muscle isoenzyme of phosphofructokinase. J Biol Chem (1990) 0.94
The mechanism of action of ethanolamine ammonia-lyase, a B12-dependent enzyme. The reversible formation of 5'-deoxyadenosine from adenosylcobalamin during the catalytic process. J Biol Chem (1974) 0.93
The mechanism of action of ethanolamine ammonia-lyase, a B 12 -dependent enzyme. 8. Further studies with compounds labeled with isotopes of hydrogen: identification and some properties of the rate-limiting step. J Biol Chem (1971) 0.92
Defective neutrophil adhesion due to an inherited deficiency of a specific glycoprotein. Trans Assoc Am Physicians (1980) 0.92
Lack of release of cytochrome C from mitochondria into cytosol early in the course of Fas-mediated apoptosis of Jurkat cells. J Biol Chem (1998) 0.92
The third component of complement: covalent attachment of a radioactive sugar to the labile binding site of C3 via the alternative pathway. J Immunol (1981) 0.92
Regulation of the activity of caspases by L-carnitine and palmitoylcarnitine. FEBS Lett (2000) 0.92
Functional defect in neutrophil cytosols from two patients with autosomal recessive cytochrome-positive chronic granulomatous disease. J Clin Invest (1989) 0.91
Events in apoptosis. Acidification is downstream of protease activation and BCL-2 protection. J Biol Chem (1996) 0.91
Kallikrein-bradykinin system in chronic alcoholic liver disease. Ann Intern Med (1972) 0.90
Inactivation of interleukin-8 by the C5a-inactivating protease from serosal fluid. Blood (1993) 0.90
The acid deoxyribonuclease of neutrophils: a possible participant in apoptosis-associated genome destruction. Blood (1995) 0.89
Isolation of a complex of respiratory burst oxidase components from resting neutrophil cytosol. Biochemistry (1994) 0.89
Identification of the NADPH-binding subunit of the respiratory burst oxidase. J Biol Chem (1991) 0.89
The mechanism of action of ethanolamine deaminase. I. Studies with isotopic hydrogen and oxygen. J Biol Chem (1969) 0.89
Binding of nicotinamide adenine dinucleotide phosphate to the tetratricopeptide repeat domains at the N-terminus of p67PHOX, a subunit of the leukocyte nicotinamide adenine dinucleotide phosphate oxidase. Biochemistry (2000) 0.87
Phosphorylation of cytosolic proteins by resting and activated human neutrophils. Blood (1984) 0.87
Evidence that de novo protein synthesis participates in a time-dependent augmentation of the chemotactic peptide-induced respiratory burst in neutrophils. Effects of recombinant human colony stimulating factors and dihydrocytochalasin B. Free Radic Biol Med (1988) 0.86
Kallikrein-kinin system in postgastrectomy dumping syndrome. Ann Intern Med (1974) 0.86
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. The source of the third methyl hydrogen in the 5'-deoxyadenosine generated from the cofactor during catalysis. J Biol Chem (1976) 0.85
Activity of the leukocyte NADPH oxidase in whole neutrophils and cell-free neutrophil preparations stimulated with long-chain polyunsaturated fatty acids. Inflammation (2001) 0.84
A chemotactic inhibitor in synovial fluid. Immunology (1983) 0.84