Published in J Lipid Res on July 01, 1971
Control of 25-hydroxycholecalciferol metabolism by parathyroid glands. Proc Natl Acad Sci U S A (1972) 2.77
Phenobarbital-induced alterations in vitamin D metabolism. J Clin Invest (1972) 2.33
Regulation by calcium of in vivo synthesis of 1,25-dihydroxycholecalciferol and 21,25-dihydroxycholecalciferol. Proc Natl Acad Sci U S A (1971) 2.27
Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium. J Clin Invest (1979) 2.21
Determination of vitamin D and its metabolites in plasma from normal and anephric man. Biochem J (1979) 1.58
Intestinal calcium absorption in exogenous hypercortisonism. Role of 25-hydroxyvitamin D and corticosteroid dose. J Clin Invest (1977) 1.37
25-hydroxycholecalciferol stimulation of muscle metabolism. J Clin Invest (1975) 1.22
In vitro production of 1,25-dihydroxyvitamin D3 by rat placental tissue. Proc Natl Acad Sci U S A (1979) 1.17
The effect of hepatectomy on the synthesis of 25-hydroxyvitamin D3. J Clin Invest (1976) 1.12
Measurement of mammalian 25-hydroxyvitamin D3 24R-and 1 alpha-hydroxylase. Proc Natl Acad Sci U S A (1981) 1.11
Vitamin D deficiency in Turkish mothers and their neonates and in women of reproductive age. J Clin Res Pediatr Endocrinol (2009) 1.08
Regulation of vitamin D metabolism: factors influencing the rate of formation of 1,25-dihydroxycholecalciferol by kidney homogenates. Biochem J (1973) 1.02
Immunological and immunoassay studies of the binding protein for vitamin D and its metabolites in human serum. J Clin Invest (1977) 1.01
23,25-Dihydroxyvitamin D3: a natural precursor in the biosynthesis of 25-hydroxyvitamin D3-26,23-lactone. Proc Natl Acad Sci U S A (1981) 0.96
Effects of cortisone administration on the metabolism and localization of 25-hydroxycholecalciferol in the rat. J Clin Invest (1973) 0.92
Salmon calcitonin-induced stimulation of 1 alpha,25-dihydroxycholecalciferol synthesis in rats involving a mechanism independent of adenosine 3':5'-cyclic monophosphate. Biochem J (1979) 0.92
Role of kidney tissue in the production of 25-hydroxyvitamin D3-26,23-lactone and 1 alpha, 25-dihydroxyvitamin D3-26,23-lactone. Proc Natl Acad Sci U S A (1980) 0.92
Parathyroidectomy reduces 25-hydroxyvitamin D3-1 alpha-hydroxylase activity in the hypocalcemic vitamin D-deficient chick. J Clin Invest (1977) 0.89
The effect of Prednisolone upon the metabolism and action of 25-hydroxy-and 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A (1974) 0.88
Effects of dietary calcium restriction and chronic thyroparathyroidectomy on the metabolism of (3H)25-hydroxyvitamin D3 and the active transport of calcium by rat intestine. J Clin Invest (1974) 0.84
Quantitative studies of the interaction of cholecalciferol ((vitamin D3) and its metabolites with different genetic variants of the serum binding protein for these sterols. Biochem J (1979) 0.84
Kinetics of liver microsomal cholecalciferol 25-hydroxylase in vitamin D-depleted and -repleated rats. Biochem J (1978) 0.81
Incorportion of oxygen-18 into the 25-position of cholecalciferol by hepatic cholecalciferol 25-hydroxylase. Biochem J (1978) 0.80
Stimulatory effect of prostaglandin E2 on 1 alpha,25-dihydroxyvitamin D3 synthesis in rats. Biochem J (1983) 0.80
Phenobarbital-induced alterations in the metabolism of [3H]vitamin D3 by the perfused rachitic rat liver in vitro. J Clin Invest (1979) 0.78
Kinetic analysis of 25-hydroxyvitamin D3 metabolism in strontium-induced rickets in the chick. J Clin Invest (1977) 0.76
Vitamin D metabolism and its possible role in the developing chick embryo. Biochem J (1981) 0.75
Comparative studies on the 25-hydroxylations of cholecalciferol and 1 alpha-hydroxycholecalfierol in perfused rat liver. Biochem J (1978) 0.75
Metabolism and biological activity of 25-fluorocholecalciferol, 24-dehydrocholecalciferol and 25-dehydrocholecalciferol in the rat. Biochem J (1979) 0.75
Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr (2000) 11.69
Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. J Clin Endocrinol Metab (1988) 7.09
Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab (2004) 6.41
Increased skin pigment reduces the capacity of skin to synthesise vitamin D3. Lancet (1982) 6.40
Epidemic influenza and vitamin D. Epidemiol Infect (2006) 5.32
Redefining vitamin D insufficiency. Lancet (1998) 5.26
Current understanding of the molecular actions of vitamin D. Physiol Rev (1998) 4.05
Metabolism of vitamin D3-3H in human subjects: distribution in blood, bile, feces, and urine. J Clin Invest (1967) 3.69
Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest (1985) 3.59
Biologically active metabolite of vitamin D3 from bone, liver, and blood serum. J Lipid Res (1966) 3.39
Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation. J Clin Endocrinol Metab (1983) 3.27
An international comparison of serum 25-hydroxyvitamin D measurements. Osteoporos Int (1999) 3.07
Photosynthesis of previtamin D3 in human skin and the physiologic consequences. Science (1980) 3.06
25-hydroxycholecalciferol. A biologically active metabolite of vitamin D3. Biochemistry (1968) 3.01
1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci U S A (1996) 2.95
Biological activity of 25-hydroxyergocalciferol in rats. J Nutr (1970) 2.85
Ultraviolet B and blood pressure. Lancet (1998) 2.83
Control of 25-hydroxycholecalciferol metabolism by parathyroid glands. Proc Natl Acad Sci U S A (1972) 2.77
Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system. Arch Biochem Biophys (2000) 2.65
Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid. Science (1979) 2.57
1,25-dihydroxycholecalciferol: a potent stimulator of bone resorption in tissue culture. Science (1972) 2.50
Isolation and identification of 1,25-dihydroxycholecalciferol. A metabolite of vitamin D active in intestine. Biochemistry (1971) 2.50
Metabolism and mechanism of action of vitamin D. Annu Rev Biochem (1976) 2.49
"Activation" of vitamin D by the liver. J Clin Invest (1969) 2.42
Mechanism of action and metabolic fate of vitamin D. Vitam Horm (1967) 2.42
Sunscreens suppress cutaneous vitamin D3 synthesis. J Clin Endocrinol Metab (1987) 2.35
Regulation by calcium of in vivo synthesis of 1,25-dihydroxycholecalciferol and 21,25-dihydroxycholecalciferol. Proc Natl Acad Sci U S A (1971) 2.27
A sensitive, precise, and convenient method for determination of 1,25-dihydroxyvitamin D in human plasma. Arch Biochem Biophys (1976) 2.23
A possible genetic defect in 25-hydroxylation as a cause of rickets. J Pediatr (1994) 2.22
The role of the liver in the metabolism of vitamin D. J Clin Invest (1969) 2.22
Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium. J Clin Invest (1979) 2.21
Regulation of cutaneous previtamin D3 photosynthesis in man: skin pigment is not an essential regulator. Science (1981) 2.20
A rapid assay for 25-OH-vitamin D3 without preparative chromatography. J Clin Endocrinol Metab (1974) 2.20
Vitamin D and its major metabolites: serum levels after graded oral dosing in healthy men. Osteoporos Int (1998) 2.07
1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr (1998) 2.06
Evidence that increased circulating 1 alpha, 25-dihydroxyvitamin D is the probable cause for abnormal calcium metabolism in sarcoidosis. J Clin Invest (1979) 2.02
Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression. Proc Natl Acad Sci U S A (1990) 1.99
Vitamin D: recent advances. Annu Rev Biochem (1983) 1.99
The synthesis of [1,2-3H]vitamin D3 and the tissue localization of a 0.25-mu-g (10 IU) dose per rat. Biochemistry (1966) 1.99
Vitamin D metabolism: the role of kidney tissue. Science (1971) 1.91
Hypervitaminosis D associated with drinking milk. N Engl J Med (1992) 1.90
Vitamin D deficiency suppresses cell-mediated immunity in vivo. Arch Biochem Biophys (1993) 1.89
Regulation of vitamin D metabolism and function. Physiol Rev (1973) 1.88
Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3. Biochim Biophys Acta (1994) 1.85
Age, vitamin D, and solar ultraviolet. Lancet (1989) 1.82
Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. Science (1982) 1.80
Identification of 1,25-dihydroxycholecalciferol, a form of vitamin D3 metabolically active in the intestine. Proc Natl Acad Sci U S A (1971) 1.78
Biological activity of 1,25-dihydroxycholecalciferol. Biochemistry (1971) 1.77
DNA sequences in the rat osteocalcin gene that bind the 1,25-dihydroxyvitamin D3 receptor and confer responsiveness to 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A (1990) 1.77
Methods for the determination of the circulating concentration of 25-hydroxyvitamin D. J Nutr Biochem (1990) 1.76
Cloning of the human 1 alpha,25-dihydroxyvitamin D-3 24-hydroxylase gene promoter and identification of two vitamin D-responsive elements. Biochim Biophys Acta (1995) 1.69
Human prostate cells synthesize 1,25-dihydroxyvitamin D3 from 25-hydroxyvitamin D3. Cancer Epidemiol Biomarkers Prev (1998) 1.69
21,25-dihydroxycholecalciferol. A metabolite of vitamin D3 preferentially active on bone. Biochemistry (1970) 1.65
An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston. Am J Clin Nutr (1990) 1.65
Monoclonal antibodies to the porcine intestinal receptor for 1,25-dihydroxyvitamin D3: interaction with distinct receptor domains. Biochemistry (1986) 1.64
The response of intestinal calcium transport to 25-hydroxy and 1,25-dihydroxy vitamin D in nephrectomized rats. Endocrinology (1972) 1.63
Race/ethnic differences in bone mineral density in men. Osteoporos Int (2007) 1.63
Isolation and identification of 24,25-dihydroxycholecalciferol, a metabolite of vitamin D made in the kidney. Biochemistry (1972) 1.62
25-Hydroxycholecalciferol-1-hydroxylase. Subcellular location and properties. J Biol Chem (1972) 1.62
25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue. Lancet (2001) 1.61
Subcellular location of vitamin D and its metabolites in intestinal mucosa after a 10-IU dose. Biochemistry (1967) 1.61
1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells. Proc Natl Acad Sci U S A (1983) 1.60
Vitamin-D-dependent rickets type II. Resistance of target organs to 1,25-dihydroxyvitamin D. N Engl J Med (1978) 1.59
25-hydroxycholecalciferol. The probable metabolically active form of vitamin D3: its identification and subcellular site of action. Arch Intern Med (1969) 1.58
Determination of vitamin D and its metabolites in plasma from normal and anephric man. Biochem J (1979) 1.58
The kidney as an endocrine organ for the production of 1,25-dihydroxyvitamin D 3 , a calcium-mobilizing hormone. N Engl J Med (1973) 1.54
1 alpha,25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production of the monokine, mononuclear cell factor. J Clin Invest (1984) 1.52
Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med (2001) 1.51
Pathogenesis of hereditary vitamin-D-dependent rickets. An inborn error of vitamin D metabolism involving defective conversion of 25-hydroxyvitamin D to 1 alpha,25-dihydroxyvitamin D. N Engl J Med (1973) 1.50
Response of intestinal calcium transport and bone calcium mobilization to 1,25-dihydroxyvitamin D3 in thyroparathyroidectomized rats. Endocrinology (1974) 1.48
In vitro production of 25-hydroxycholecalciferol. Biochem Biophys Res Commun (1969) 1.48
Serum vitamin D metabolite levels and the subsequent development of prostate cancer (Hawaii, United States) Cancer Causes Control (1998) 1.46
Effect of vitamin D supplementation and ultraviolet B exposure on serum 25-hydroxyvitamin D concentrations in healthy volunteers: a randomized, crossover clinical trial. Br J Dermatol (2013) 1.46
Mitochondrial cytochrome p450. A component of chick kidney 25-hydrocholecalciferol-1alpha-hydroxylase. J Biol Chem (1974) 1.45
Rat intestinal 25-hydroxyvitamin D3- and 1alpha,25-dihydroxyvitamin D3-24-hydroxylase. J Biol Chem (1978) 1.44
Current concepts. Vitamin D. N Engl J Med (1969) 1.43
Dietary calcium is a major factor in 1,25-dihydroxycholecalciferol suppression of experimental autoimmune encephalomyelitis in mice. J Nutr (1999) 1.41
1,25-dihydroxyvitamin D3 is a positive regulator for the two anti-encephalitogenic cytokines TGF-beta 1 and IL-4. J Immunol (1998) 1.41
Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A (1992) 1.41
1,25-dihydroxycholecalciferol stimulates osteoclasts in rat bones in the absence of parathyroid hormone. Endocrinology (1981) 1.40
25,26-dihydroxycholecalciferol, a metabolite of vitamin D3 with intestinal calcium transport activity. Biochemistry (1970) 1.40
Serum 1,25-dihydroxyvitamin D levels in normal subjects and in patients with hereditary rickets or bone disease. N Engl J Med (1978) 1.40
The vitamin D system in the regulation of calcium and phosphorus metabolism. Nutr Rev (1979) 1.39
High prevalence of vitamin D deficiency, secondary hyperparathyroidism and generalized bone pain in Turkish immigrants in Germany: identification of risk factors. Osteoporos Int (2006) 1.39
A specific high-affinity binding macromolecule for 1,25-dihydroxyvitamin D3 in fetal bone. Science (1977) 1.38
Parathyroid hormone activation of the 25-hydroxyvitamin D3-1alpha-hydroxylase gene promoter. Proc Natl Acad Sci U S A (1998) 1.38
Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues. Cancer Res (1984) 1.37
Effect of estrogen on calcium absorption and serum vitamin D metabolites in postmenopausal osteoporosis. J Clin Endocrinol Metab (1980) 1.37
Metabolism of tritiated vitamin D3 in familial vitamin D-resistant rickets with hypophosphatemia. J Pediatr (1967) 1.37
Vitamin D: the vitamin and the hormone. Fed Proc (1974) 1.36
Vitamin D stimulated, calcium-dependent adenosine triphosphatase from brush borders of rat small intestine. Biochem Biophys Res Commun (1969) 1.35
Effect of 1 alpha,25-dihydroxyvitamin D3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions. J Invest Dermatol (1986) 1.35
Stimulation of 25-hydroxyvitamin D3-1alpha-hydroxylase by phosphate depletion. J Biol Chem (1976) 1.34