Published in Proc Natl Acad Sci U S A on August 01, 1974
Control of B-lymphocyte function. I. Inactivation of mitogenesis by interactions with surface immunoglobulin and Fc-receptor molecules. J Exp Med (1976) 1.59
Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen. J Exp Med (1976) 1.48
Antigen-induced aggregation and modulation of receptors on hapten-specific B lymphocytes. J Exp Med (1976) 1.12
Induction if immunological tolerance to the major antigenic determinant of penicillin: a therapeutic approach to penicillin allergy. Proc Natl Acad Sci U S A (1976) 0.90
Immunological tolerance to allergenic protein determinants: a therapeutic approach for selective inhibition of IgE antibody production. Proc Natl Acad Sci U S A (1979) 0.80
An enzymic method for the trace iodination of immunoglobulins and other proteins. Biochem J (1969) 14.06
Ligand-induced movement of lymphocyte membrane macromolecules. I. Analysis by immunofluorescence and ultrastructural radioautography. J Exp Med (1972) 5.01
Inhibition of secondary anti-hapten responses with the hapten conjugated to type 3 pneumococcal polysaccharide. Eur J Immunol (1972) 2.14
Nonantigenicity and immunologic tolerance: the role of the carrier in the induction of tolerance to the hapten. J Exp Med (1971) 2.02
Redistribution and fate of Ig complexes on surface of B lymphocytes: functional implications and mechanisms. Transplant Rev (1973) 1.88
Immunological tolerance in bone marrow-derived lymphocytes. I. Evidence for an intracellular mechanism of inactivation of hapten-specific precursors of antibody-forming cells. J Exp Med (1972) 1.86
The effect of the carrier protein on the immune response and on the induction of tolerance in mice to the 2,4-dinitrophenyl determinant. Immunology (1969) 1.48
Hapten-specific tolerance: unresponsiveness in the T cell-depleted population. Eur J Immunol (1973) 1.47
Induction of B cell tolerance in vitro to 2,4-dinitrophenyl coupled to a copolymer of D-glutamic acid and D-lysine (DNP-D-GL). J Exp Med (1973) 1.45
The allogeneic effect in inbred mice. 3. Unique antigenic structural requirements in the expression of the phenomenon on unprimed cell populations in vivo. J Exp Med (1973) 1.35
Induction of immunological tolerance by a hapten (DNP) bound to a non-immunogenic protein carrier. Nat New Biol (1971) 1.34
Hapten-specific tolerance. Preferential depression of the high affinity antibody response. J Exp Med (1972) 1.31
Events after the binding of antigen to lymphocytes: removal and regeneration of the antigen receptor. J Exp Med (1974) 1.25
Immunological tolerance to a hapten. I. Induction and maintenance of tolerance to trinitrophenyl with trinitrobenzene sulfonic acid. J Exp Med (1973) 1.19
Histocompatibility-linked immune response genes. Science (1972) 16.79
The regulatory influence of activated T cells on B cell responses to antigen. Adv Immunol (1972) 9.43
Genetic control of specific immune responses. Adv Immunol (1969) 8.81
Properties of antibodies cytophilic for macrophages. J Exp Med (1966) 8.64
Binding of immunogenic peptides to Ia histocompatibility molecules. Nature (1985) 8.39
Requirement of thymus (T) lymphocytes for resistance to listeriosis. J Exp Med (1972) 8.25
Immunoglobulins on the surface of lymphocytes. I. Distribution and quantitation. J Exp Med (1971) 8.22
Antigen-presenting function of the macrophage. Annu Rev Immunol (1984) 7.83
Cell interactions between histoincompatible T and B lymphocytes. VII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex. J Exp Med (1975) 7.64
Monoclonal dinitrophenyl-specific murine IgE antibody: preparation, isolation, and characterization. J Immunol (1980) 6.69
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. Proc Natl Acad Sci U S A (1993) 6.33
Cell selection by antigen in the immune response. Adv Immunol (1969) 6.05
The function and interrelationships of T-cell receptors, Ir genes and other histocompatibility gene products. Transplant Rev (1975) 5.88
Carrier function in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization. J Exp Med (1970) 5.71
Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid 60-L-alanine 30-L-tyrosine 10 (GAT). J Exp Med (1974) 5.55
Immunoglobulins on the surface of lymphocytes. II. The bone marrow as the main source of lymphocytes with detectable surface-bound immunoglobulin. J Exp Med (1971) 5.43
Critical role of determinant presentation in the induction of specific responses in immunocompetent lymphocytes. J Exp Med (1973) 5.30
The allogeneic effect on immune responses: model for regulatory influences of T lymphocytes on the immune system. Transplant Rev (1972) 5.23
A hypothesis to relate the specificity of T lymphocytes and the activity of I region-specific Ir genes in macrophages and B lymphocytes. J Immunol (1978) 5.07
New procedures for preparation and isolation of conjugates of proteins and a synthetic copolymer of D-amino acids and immunochemical characterization of such conjugates. Biochemistry (1979) 5.02
Ligand-induced movement of lymphocyte membrane macromolecules. I. Analysis by immunofluorescence and ultrastructural radioautography. J Exp Med (1972) 5.01
Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon. J Exp Med (1983) 4.92
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells. Proc Natl Acad Sci U S A (1982) 4.85
Role of MHC gene products in immune regulation. Science (1981) 4.84
The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages. Adv Immunol (1981) 4.72
The allogeneic effect in inbred mice. II. Establishment of the cellular interactions required for enhancement of antibody production by the graft-versus-host reaction. J Exp Med (1972) 4.70
Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice. J Immunol (1989) 4.70
The regulatory role of macrophages in antigenic stimulation. Adv Immunol (1972) 4.69
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature (1990) 4.59
The behavior of hapten-poly-L-lysine conjugates as complete antigens in genetic responder and as haptens in nonresponder guinea pigs. J Exp Med (1966) 4.58
The basis for the immunoregulatory role of macrophages and other accessory cells. Science (1987) 4.51
Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proc Natl Acad Sci U S A (1984) 4.43
Functional specificity of thymus- dependent lymphocytes. Science (1977) 4.31
Carrier function in anti-hapten antibody responses. 3. Stimulation of antibody synthesis and facilitation of hapten-specific secondary antibody responses by graft-versus-host reactions. J Exp Med (1971) 4.29
Membrane and cytoplasmic changes in B lymphocytes induced by ligand-surface immunoglobulin interaction. Adv Immunol (1976) 4.18
Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli. Infect Immun (1991) 4.18
Cell interactions between histoincompatible T and B lymphocytes. The H-2 gene complex determines successful physiologic lymphocyte interactions. Proc Natl Acad Sci U S A (1973) 4.12
Cell interactions between histoincompatible T and B lymphocytes. IV. Involvement of the immune response (Ir) gene in the control of lymphocyte interactions in responses controlled by the gene. J Exp Med (1973) 4.05
Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes. J Immunol (1981) 3.94
A single major pathway of T-lymphocyte interactions in antigen-specific immune suppression. Scand J Immunol (1981) 3.85
Prostaglandins modulate macrophage Ia expression. Nature (1982) 3.83
Experimental glomerulonephritis: immunological events and pathogenetic mechanisms. Adv Immunol (1967) 3.83
Activated macrophages induce vascular proliferation. Nature (1977) 3.74
Antigen presentation: comments on its regulation and mechanism. J Immunol (1984) 3.68
Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT). J Immunol (1976) 3.64
Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production. J Immunol (1982) 3.61
The immune response genes of the major histocompatibility complex. Immunol Rev (1978) 3.61
A T cell-independent mechanism of macrophage activation by interferon-gamma. J Immunol (1987) 3.55
Activation of T and B lymphocytes in vitro. II. Biological and biochemical properties of an allogeneic effect factor (AEF) active in triggering specific B lymphocytes. J Exp Med (1974) 3.54
The effect of the amount of mycobacterial adjuvants on the immune response of strain 2, strain 13 and Hartley strain guinea pigs to DNP-PLL and DNP-GL. J Immunol (1969) 3.53
Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma. J Immunol (1994) 3.50
Natural immunity: a T-cell-independent pathway of macrophage activation, defined in the scid mouse. Immunol Rev (1991) 3.49
Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli. J Immunol (1980) 3.46
Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas. J Immunol (1984) 3.41
Identification of a membrane-associated interleukin 1 in macrophages. Proc Natl Acad Sci U S A (1985) 3.39
Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice. Infect Immun (1993) 3.38
Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. J Exp Med (1984) 3.36
Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor. J Exp Med (1974) 3.29
Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci U S A (1993) 3.27
Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2. J Exp Med (1981) 3.27
Antigen- and receptor-driven regulatory mechanisms. IV. Idiotype-bearing I-J+ suppressor T cell factors induce second-order suppressor T cells which express anti-idiotypic receptors. J Exp Med (1980) 3.21
Genetic control of specific immune suppression. II. H-2-linked dominant genetic control of immune suppression by the random copolymer L-glutamic acid50-L-tyrosine50 (GT). J Exp Med (1975) 3.17
Regulation by the H-2 gene complex of macrophage-lymphoid cell interactions in secondary antibody responses in vitro. J Exp Med (1976) 3.10
Interleukin 1 is processed and released during apoptosis. Proc Natl Acad Sci U S A (1991) 3.09
Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope. Nature (1987) 3.08
A mononuclear cell component in experimental immunological glomerulonephritis. J Exp Med (1978) 3.02
Secondary antibody responses in haptenic systems: cell population selection by antigen. J Immunol (1967) 3.01
Genetic control of immune responses in vitro. 3. Tolerogenic properties of the terpolymer L-glutamic acid 60-L-alanine30-L-tyrosine10 (GAT) for spleen cells from nonresponder (H-2s and H-2q) mice. J Exp Med (1974) 3.01
Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J Immunol (1981) 2.94
Macrophage-T cell interactions involving Listeria monocytogenes--role of the H-2 gene complex. J Immunol (1979) 2.93
Persistence of immunogenicity of antigen after uptake by macrophages. J Exp Med (1968) 2.93
Activation of T and B lymphocytes in vitro. I. Regulatory influence of bacterial lipopolysaccharide (LPS) on specific T-cell helper function. J Exp Med (1974) 2.90
Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proc Natl Acad Sci U S A (1997) 2.89
Linkage between the poly-L-lysine gene and the locus controlling the major histocompatibility antigens in strain 2 guinea pigs. Proc Natl Acad Sci U S A (1970) 2.89
Complementation of H-2-linked Ir genes in the mouse. Proc Natl Acad Sci U S A (1975) 2.88
Genetic control of specific immune suppression. I. Experimental conditions for the stimulation of suppressor cells by the copolymer L-glutamic acid50-L-tyrosine50 (GT) in nonresponder BALB/c mice. J Exp Med (1975) 2.78
Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. J Immunol (1993) 2.73
The costimulatory function of antigen-presenting cells. Immunol Today (1990) 2.71
The binding of clathrin triskelions to membranes from coated vesicles. Cell (1981) 2.70
The immune response of mice to antigen in macrophages. Immunology (1968) 2.67
An ultrastructural study of lymphocytes with surface-bound immunoglobulin. J Exp Med (1972) 2.65
The histocompatibility-linked immune response genes. Adv Cancer Res (1975) 2.64
Suppressor cells and immunoregulation. Annu Rev Immunol (1984) 2.63
Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon. J Immunol (1983) 2.61
Genetic control of immune responsiveness to a glutamic acid, alanine, tyrosine copolymer in mice. I. Linkage of responsiveness to H-2 genotype. J Immunol (1971) 2.60