Ethionine fatty liver.

PubWeight™: 1.26‹?› | Rank: Top 10%

🔗 View Article (PMID 4866070)

Published in Adv Lipid Res on January 01, 1967

Authors

E Farber

Articles citing this

Subcellular localization of B apoprotein of plasma lipoproteins in rat liver. J Cell Biol (1976) 1.81

Colchicine-induced inhibition of lipoprotein and protein secretion into the serum and lack of interference with secretion of biliary phospholipids and cholesterol by rat liver in vivo. J Cell Biol (1974) 1.46

Molecular aspects of the in vivo and in vitro effects of ethionine, an analog of methionine. Microbiol Rev (1982) 1.30

Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate. Am J Pathol (1975) 1.04

Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine. Biochem J (1971) 0.98

The biochemical pathology of liver cell necrosis. Am J Pathol (1975) 0.92

Influence of dietary factors on the pancreatotoxicity of ethionine. Am J Pathol (1976) 0.87

Therapeutic treatment with poly(ADP-ribose) polymerase inhibitors attenuates the severity of acute pancreatitis and associated liver and lung injury. Br J Pharmacol (2007) 0.87

The effect of ethionine on ribonucleic acid synthesis in rat liver. Biochem J (1975) 0.86

Some alterations in hepatic cytosome structure and acid phosphatase activity induced by DL-ethionine. Am J Pathol (1969) 0.85

Studies of the ethylation of rat liver transfer ribonucleic acid after administration of L-ethionine. Biochem J (1972) 0.85

Hg- and Cu-induced hepatocellular changes in the mummichog, Fundulus heteroclitus. Environ Health Perspect (1986) 0.81

Cerebral ribosomal protein phosphorylation in experimental hyperphenylalaninaemia. Biochem J (1980) 0.79

Natural resolution of hepatic ultrastructural changes induced by DL-ethionine. Am J Pathol (1970) 0.75

New modes of data partitioning based on PARS peak alignment for improved multivariate biomarker/biopattern detection in (1)H-NMR spectroscopic metabolic profiling of urine. Metabolomics (2006) 0.75

The metabolism of steroids in the fatty liver induced by orotic acid feeding. Biochem J (1976) 0.75

Dynamics of injury and repair in hepatic cells. II. Association of membranes with lipid during recovery from ethionine-induced fatty liver. Am J Pathol (1971) 0.75

Biochemical lesions in copper-deficient rats caused by secondary iron deficiency. Derangement of protein synthesis and impairment of energy metabolism. Biochem J (1980) 0.75

Articles by these authors

(truncated to the top 100)

Rapid emergence of carcinogen-induced hyperplastic lesions in a new model for the sequential analysis of liver carcinogenesis. Am J Pathol (1977) 2.45

The sequential analysis of cancer development. Adv Cancer Res (1980) 2.28

Cell proliferation is not a major risk factor for cancer. Mod Pathol (1996) 2.05

The multistep nature of cancer development. Cancer Res (1984) 1.93

Hepatocarcinogenesis: a dynamic cellular perspective. Lab Invest (1987) 1.82

Cellular biochemistry of the stepwise development of cancer with chemicals: G. H. A. Clowes memorial lecture. Cancer Res (1984) 1.70

The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens. Cancer Res (1976) 1.58

Studies on the proliferation and fate of oval cells in the liver of rats treated with 2-acetylaminofluorene and partial hepatectomy. Am J Pathol (1984) 1.48

The sequential analysis of liver cancer induction. Biochim Biophys Acta (1980) 1.46

Studies on DNA repair in human lymphocytes treated with proximate carcinogens and alkylating agents. Cancer Res (1971) 1.44

Induction of resistant hepatocytes as a new principle for a possible short-term in vivo test for carcinogens. Cancer Res (1980) 1.42

Chemical carcinogenesis. N Engl J Med (1981) 1.41

Carcinogenesis--cellular evolution as a unifying thread: Presidential address. Cancer Res (1973) 1.30

The inhibition of liver ribonucleic acid synthesis by ethionine. J Biol Chem (1966) 1.30

Patterns of transfer RNA in normal rat liver and during hepatic carcinogenesis. Proc Natl Acad Sci U S A (1967) 1.27

Chemical carcinogenesis: a biologic perspective. Am J Pathol (1982) 1.26

A relative deficiency of cytochrome P-450 and aryl hydrocarbon [benzo(a)pyrene] hydroxylase in hyperplastic nodules induced by 2-acetylaminofluorene in rat liver. Cancer Res (1976) 1.26

Initiation of chemical carcinogenesis requires cell proliferation. Nature (1978) 1.25

Gamma-glutamyltransferase in putative premalignant liver cell populations during hepatocarcinogenesis. Cancer Res (1978) 1.24

The rapid acceleration of hepatic nuclear ribonucleic acid breakdown by actinomycin but not by ethionine. J Biol Chem (1968) 1.21

Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas. Proc Natl Acad Sci U S A (1987) 1.21

Differences in growth of transplants of liver, liver hyperplastic nodules, and hepatocellular carcinomas in the mammary fat pad. Am J Pathol (1977) 1.20

On the molecular pathology of ischemic renal cell death. Reversible and irreversible cellular and mitochondrial metabolic alterations. Am J Pathol (1968) 1.19

On the mechanism of induction of hepatic adenosine triphosphate deficiency by ethionine. J Biol Chem (1966) 1.19

Reversal by adenine of the ethionine-induced lipid accumulation in the endoplasmic reticulum of the rat liver. A preliminary report. J Cell Biol (1965) 1.19

Role of acute hepatic necrosis in the induction of early steps in liver carcinogenesis by diethylnitrosamine. Cancer Res (1981) 1.17

Cycloheximide, an inhibitor of peptide chain termination or release in liver in vivo and in vitro. Biochem Biophys Res Commun (1971) 1.17

Pre-cancerous steps in carcinogenesis. Their physiological adaptive nature. Biochim Biophys Acta (1984) 1.16

Biochemistry of carcinogenesis. Cancer Res (1968) 1.15

Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene. Lab Invest (1985) 1.10

The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens. Carcinogenesis (1984) 1.08

Phenotypic diversity as an early property of putative preneoplastic hepatocyte populations in liver carcinogenesis. Cancer Res (1980) 1.08

Chemicals, evolution, and cancer development: Rous-Whipple Award Lecture. Am J Pathol (1982) 1.07

ATP and cell integrity. Fed Proc (1973) 1.07

The biochemistry of preneoplastic liver: a common metabolic pattern in hepatocyte nodules. Can J Biochem Cell Biol (1984) 1.06

Nonrandom nature of in vivo methylation of dimethylnitrosamine and the subsequent removal of methylated products from rat liver chromatin DNA. Cancer Res (1976) 1.06

Effect of cycloheximide on the cell cycle of the crypts of the small intestine of the rat. J Cell Biol (1967) 1.06

Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism. Cancer Res (1967) 1.04

Newer insights into the pathogenesis of liver cancer. Am J Pathol (1977) 1.04

Hyperplastic areas, hyperplastic nodules, and hyperbasophilic areas as putative precursor lesions. Cancer Res (1976) 1.03

Molecular pathology of in-vivo inhibition of protein synthesis. Electron microscopy of rat pancreatic acinar cells in puromycin-induced necrosis. Am J Pathol (1968) 1.02

A common biochemical pattern in preneoplastic hepatocyte nodules generated in four different models in the rat. Cancer Res (1985) 1.02

Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine. Biochem J (1971) 0.98

The cancer-initiating potential of the fumonisin B mycotoxins. Carcinogenesis (1992) 0.97

Biochemical pathology. Annu Rev Pharmacol (1971) 0.97

Promotion of liver cancer development by brief exposure to dietary 2-acetylaminofluorene plus partial hepatectomy or carbon tetrachloride. Cancer Res (1983) 0.97

The biochemical pathology of inhibition of protein synthesis in vivo. The effects of cycloheximide on hepatic parenchymal cell ultrastructure. Lab Invest (1969) 0.97

Choline deficiency, lipotrope deficiency and the development of liver disease including liver cancer: a new perspective. Lab Invest (1993) 0.96

The disorganization of hepatic cell nucleoli induced by ethionine and its reversal by adenine. J Cell Biol (1968) 0.96

Kinetics of phenotypic maturation of remodeling of hyperplastic nodules during liver carcinogenesis. Cancer Res (1982) 0.96

In vitro measurement of carcinogen-resistant liver cells during hepatocarcinogenesis. Int J Cancer (1978) 0.95

Redifferentiation as a basis for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver. Cancer Res (1983) 0.95

The effect of cycloheximide on the interaction between mitochondrial respiration and gluconeogenesis in guinea pig and rat liver. J Biol Chem (1973) 0.95

Acute pancreatic necrosis induced by puromycin. Lab Invest (1967) 0.95

Alternative methods of selecting rat hepatocellular nodules resistant to 2-acetylaminofluorene. Int J Cancer (1987) 0.95

Sequential analysis of hepatic carcinogenesis: a comparative study of the ultrastructure of preneoplastic, malignant, prenatal, postnatal, and regenerating liver. Lab Invest (1979) 0.94

Inhibition of protein synthesis in rat liver by D-galactosamine. Res Commun Chem Pathol Pharmacol (1973) 0.94

Cell cycle kinetics of rat hepatocytes in early putative preneoplastic lesions in hepatocarcinogenesis. Cancer Res (1984) 0.94

Distinctive biochemical pattern associated with resistance of hepatocytes in hepatocyte nodules during liver carcinogenesis. Environ Health Perspect (1983) 0.94

Nature of early appearing, carcinogen-induced liver lesions to iron accumulation. J Natl Cancer Inst (1976) 0.93

Sequential alterations in growth control and cell dynamics of rat hepatocytes in early precancerous steps in hepatocarcinogenesis. Cancer Res (1986) 0.93

Deoxyribonucleoside incorporation and the role of hydroxyurea in a model lymphocyte system for studying DNA repair in carcinogenesis. Cancer Res (1971) 0.93

A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation. Cancer Res (1970) 0.93

The biochemical pathology of ethionine-induced pancreatic damage: ethionine incorporation into proteins, and ATP levels in pancreas of rats. Arch Biochem Biophys (1968) 0.92

The binding of 2-acetylaminofluorene to rat liver ribonucleic acid in vivo. Cancer Res (1965) 0.92

Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionine. Cancer Lett (1984) 0.91

Effects of ethionine on adenosine triphosphate levels and ionic composition of liver cell nuclei. J Biol Chem (1968) 0.91

Chordoma: a case report. Surg Neurol (1997) 0.91

Initiation and selection of resistant hepatocyte nodules in rats given the pyrrolizidine alkaloids lasiocarpine and senecionine. Cancer Res (1985) 0.90

The effects of cycloheximide on energy transfer in rat and guinea pig liver mitochondria. J Biol Chem (1973) 0.90

Highly selective in vivo ethylation of rat liver nuclear protein by ethionine. Biochem Biophys Res Commun (1969) 0.90

Sequential analysis of hepatic carcinogenesis: the comparative architecture of preneoplastic, malignant, prenatal, postnatal and regenerating liver. Br J Cancer (1979) 0.90

Comparison of the blood supply to diethylnitrosamine-induced hyperplastic nodules and hepatomas and to the surrounding liver. Cancer Res (1977) 0.90

Multiplicity of induction patterns of rat liver microsomal mono-oxygenases and other polypeptides produced by administration of various xenobiotics. Biochem J (1979) 0.90

Putative precursor lesions: summary and some analytical considerations. Cancer Res (1976) 0.89

Morphologic and metabolic alterations in hepatic cell nucleoli induced by varying doses of actinomycin D. Cancer Res (1969) 0.89

Chemical carcinogenesis: persistence of bound forms of 2-fluorenylacetamide. Science (1968) 0.89

The effects of inosine and aminoimidazole carboxamide upon the ethionine fatty liver. Biochem Pharmacol (1965) 0.88

A new common marker for premalignant and malignant hepatocytes induced in the rat by chemical carcinogens. J Natl Cancer Inst (1975) 0.88

Interaction between ethionine and rat liver ribonucleic acid and protein in vivo. Cancer Res (1967) 0.88

Allogeneic hepatocyte transplantation in the rat spleen under cyclosporine immunosuppression. Transplantation (1986) 0.88

A characteristic electrophoretic pattern of cytosolic polypeptides from hepatocyte nodules generated during liver carcinogenesis in several models. Biochem Biophys Res Commun (1983) 0.88

Dynamics of liver cell injury and repair. I. Spontaneous reformation of the nucleolus and polyribosomes in the presence of extensive cytoplasmic damage induced by ethionine. Lab Invest (1970) 0.87

The rapid induction of liver cell death in rats fed a choline-deficient methionine-low diet. Am J Pathol (1983) 0.87

Localization of alpha-fetoprotein by immunofluorescence in hyperplastic nodules during hepatocarcinogenesis induced by 2-acetylaminofluorene. Cancer Res (1974) 0.86

Transitory DNA hypomethylation during liver cell proliferation induced by a single dose of lead nitrate. Arch Biochem Biophys (1991) 0.86

Resistant hepatocytes as early changes in liver induced by polycyclic aromatic hydrocarbons. Int J Cancer (1980) 0.86

Inverse relationship between epidermal growth factor induced proliferation and expression of high affinity surface epidermal growth factor receptors in rat hepatocytes. Lab Invest (1989) 0.86

Differential effects of hydroxyurea on survival of proliferating cells in vivo. Cancer Res (1969) 0.85

Chemical carcinogenesis: a current biological perspective. Carcinogenesis (1984) 0.85

Gamma-glutamyl transpeptidase: a positive marker for cultured rat liver cells derived from putative premalignant and malignant lesions. J Natl Cancer Inst (1978) 0.85

A choline-devoid diet, carcinogenic in the rat, induces DNA damage and repair. Carcinogenesis (1986) 0.84

Pathogenesis of liver cancer. Arch Pathol (1974) 0.84

Resistance of liver polysomes to ATP deficiency in the male rat. Biochim Biophys Acta (1969) 0.84

Identification of a characteristic cytosolic polypeptide of rat preneoplastic hepatocyte nodules as placental glutathione S-transferase. Biochem Biophys Res Commun (1987) 0.84

Preneoplastic antigen as a marker for endoplasmic reticulum of putative premalignant hepatocytes during liver carcinogenesis. Cancer Res (1977) 0.84

Cellular analysis of liver carcinogenesis. 3. Comparison of the ultrastructure of hyperplastic liver nodules and hepatocellular carcinomas induced in rat liver by 2-fluorenylacetamide. J Natl Cancer Inst (1969) 0.84

Transfer of viable putative preneoplastic hepatocytes to the livers of syngeneic host rats. J Natl Cancer Inst (1978) 0.84

Chemical carcinogenesis: the liver as a model. Pathol Immunopathol Res (1986) 0.84

Evidence for the hormone dependency of hepatic hyperplastic nodules: inhibition of malignant transformation after exogenous 17 beta-estradiol and tamoxifen. Hepatology (1983) 0.84