Published in Proc Natl Acad Sci U S A on January 01, 1970
Slippage synthesis of simple sequence DNA. Nucleic Acids Res (1992) 5.18
Insertional mutagenesis of Listeria monocytogenes with a novel Tn917 derivative that allows direct cloning of DNA flanking transposon insertions. J Bacteriol (1990) 4.82
Method for determining whether a gene of Escherichia coli is essential: application to the polA gene. J Bacteriol (1984) 4.36
Sequence of the C. elegans transposable element Tc1. Nucleic Acids Res (1983) 4.32
Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli. Proc Natl Acad Sci U S A (1983) 4.22
Synthesis of human fibroblast interferon by E. coli. Nucleic Acids Res (1980) 3.75
High sequence specificity of micrococcal nuclease. Nucleic Acids Res (1981) 3.66
Construction and properties of Tn917-lac, a transposon derivative that mediates transcriptional gene fusions in Bacillus subtilis. Proc Natl Acad Sci U S A (1986) 3.42
A conditional lethal mutant of Escherichia coli K12 defective in the 5' leads to 3' exonuclease associated with DNA polymerase I. Proc Natl Acad Sci U S A (1974) 3.42
Precise location of DNase I cutting sites in the nucleosome core determined by high resolution gel electrophoresis. Nucleic Acids Res (1979) 2.85
Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus. J Clin Invest (1980) 2.80
Characterization of the promoter region of the Bacillus subtilis spoIIE operon. J Bacteriol (1988) 2.60
Detection of the catalytic activities of DNA polymerases and their associated exonucleases following SDS-polyacrylamide gel electrophoresis. Nucleic Acids Res (1981) 2.56
A method for prediction of the locations of linker regions within large multifunctional proteins, and application to a type I polyketide synthase. J Mol Biol (2002) 2.41
DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism. EMBO J (1992) 2.15
Characterization of promoter-cloning plasmids: analysis of operon structure in the rif region of Escherichia coli and isolation of an enhanced internal promoter mutant. J Bacteriol (1980) 2.13
Site-specific mutagenesis on cloned DNAs: generation of a mutant of Escherichia coli tyrosine suppressor tRNA in which the sequence G-T-T-C corresponding to the universal G-T-pseudouracil-C sequence of tRNAs is changed to G-A-T-C. Proc Natl Acad Sci U S A (1981) 2.09
Defined transversion mutations at a specific position in DNA using synthetic oligodeoxyribonucleotides as mutagens. Nucleic Acids Res (1979) 1.99
Conformation takes precedence over sequence in adeno-associated virus DNA replication. Mol Cell Biol (1984) 1.96
Distinct characteristics of loop sequences of two Drosophila foldback transposable elements. Nucleic Acids Res (1985) 1.92
Nucleotide sequence preservation of human mitochondrial DNA. Proc Natl Acad Sci U S A (1985) 1.88
Insertion mutant of bacteriophage f1 sensitive to EcoRI. Proc Natl Acad Sci U S A (1979) 1.76
Genome organization of RNA tumor viruses. I. In vitro synthesis of full-genome-length single-stranded and double-stranded viral DNA transcripts. J Virol (1978) 1.68
Characterization of Lactococcus lactis UV-sensitive mutants obtained by ISS1 transposition. J Bacteriol (1997) 1.61
Sequence of 1060 3'-terminal nucleotides of poliovirus RNA as determined by a modification of the dideoxynucleotide method. Proc Natl Acad Sci U S A (1980) 1.61
New insights into the formation of fungal aromatic polyketides. Nat Rev Microbiol (2010) 1.59
Maize streak virus genes essential for systemic spread and symptom development. EMBO J (1989) 1.43
Macromolecular crowding increases binding of DNA polymerase to DNA: an adaptive effect. Proc Natl Acad Sci U S A (1987) 1.42
Structure of a Bacillus subtilis bacteriophage SPO1 gene encoding RNA polymerase sigma factor. Proc Natl Acad Sci U S A (1983) 1.36
Two Drosophila melanogaster tropomyosin genes: structural and functional aspects. Mol Cell Biol (1986) 1.35
A 5' to 3' exonuclease functionally interacts with calf DNA polymerase epsilon. Proc Natl Acad Sci U S A (1992) 1.31
Role of the Escherichia coli nucleotide excision repair proteins in DNA replication. J Bacteriol (2000) 1.18
Mutations in the lacY gene of Escherichia coli define functional organization of lactose permease. Proc Natl Acad Sci U S A (1981) 1.16
Rapid identification of genes encoding DNA polymerases by function-based screening of metagenomic libraries derived from glacial ice. Appl Environ Microbiol (2009) 1.14
Cleavage of supercoiled plasmid DNA by autoantibody Fab fragment: application of the flow linear dichroism technique. Proc Natl Acad Sci U S A (1995) 1.08
Structure of the promoter of the Dictyostelium discoideum prespore EB4 gene. Mol Cell Biol (1985) 1.08
Nucleoside diphosphokinase activity associated with DNA polymerases. Proc Natl Acad Sci U S A (1971) 1.04
Single-molecule microscopy reveals new insights into nucleotide selection by DNA polymerase I. Nucleic Acids Res (2012) 1.01
Requirement for the polymerization and 5'-->3' exonuclease activities of DNA polymerase I in initiation of DNA replication at oriK sites in the absence of RecA in Escherichia coli rnhA mutants. J Bacteriol (1993) 0.98
A complex repeated DNA sequence within the Drosophila transposable element copia. Nucleic Acids Res (1981) 0.98
Structure of cloned delta-globin genes from a normal subject and a patient with delta-thalassemia; sequence polymorphisms found in the delta-globin gene region of Japanese individuals. Nucleic Acids Res (1982) 0.97
Enzymes used in molecular biology: a useful guide. J Cell Commun Signal (2008) 0.95
Temperature dependence and thermodynamics of Klenow polymerase binding to primed-template DNA. Biophys J (2005) 0.94
Proteolytic footprinting of transcription factor TFIIIA reveals different tightly binding sites for 5S RNA and 5S DNA. Mol Cell Biol (1993) 0.94
On the influence of thymidine analogues on the activity of phage fd promoters in vitro. Nucleic Acids Res (1980) 0.93
Characterization of a new murine cellular DNA polymerase. Proc Natl Acad Sci U S A (1974) 0.92
Reconstitution of active catalytic trimer of aspartate transcarbamoylase from proteolytically cleaved polypeptide chains. Protein Sci (1993) 0.92
Catalytic editing properties of DNA polymerases. Proc Natl Acad Sci U S A (1995) 0.88
Demystified ... DNA nucleotide sequencing. Mol Pathol (1999) 0.87
The sequence of sequencers: The history of sequencing DNA. Genomics (2015) 0.86
Exonuclease IX of Escherichia coli. Nucleic Acids Res (1998) 0.85
DNA polymerase I in constitutive stable DNA replication in Escherichia coli. J Bacteriol (1997) 0.85
Boronic acid-modified DNA that changes fluorescent properties upon carbohydrate binding. Chem Commun (Camb) (2010) 0.83
Physical locus of the DNA polymerase gene and genetic maps of bacteriophage T5 mutants. J Virol (1985) 0.83
Sufficiency of the Klenow fragment for survival of polC(Ts) pcbA1 Escherichia coli at 43 degrees C. J Bacteriol (1988) 0.82
Research applications of proteolytic enzymes in molecular biology. Biomolecules (2013) 0.81
Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imaging. Biophys J (2014) 0.81
Molecular dynamics study of the opening mechanism for DNA polymerase I. PLoS Comput Biol (2014) 0.81
Enzyme screening with synthetic multifunctional pores: focus on biopolymers. Proc Natl Acad Sci U S A (2003) 0.79
Dinucleotides as products of an exonucleolytic activity association with the Micrococcus luteus DNA polymerase. Proc Natl Acad Sci U S A (1970) 0.79
The deletion of rnhB in Mycobacterium smegmatis does not affect the level of RNase HII substrates or influence genome stability. PLoS One (2015) 0.79
Sequencing of first-strand cDNA library reveals full-length transcriptomes. Nat Commun (2015) 0.79
Studying DNA-protein interactions with single-molecule Förster resonance energy transfer. Protoplasma (2013) 0.78
Multiple molecular species of Escherichia coli DNA polymerase. Proc Natl Acad Sci U S A (1971) 0.78
Influence of template inactivators on the binding of DNA polymerase to DNA. Nucleic Acids Res (1974) 0.77
The DNA Exonucleases of Escherichia coli. Ecosal Plus (2011) 0.77
Characterization of dark quencher chromophores as nonfluorescent acceptors for single-molecule FRET. Biophys J (2012) 0.77
The Closing Mechanism of DNA Polymerase I at Atomic Resolution. Structure (2015) 0.76
Enhancement of Polymerase Activity of the Large Fragment in DNA Polymerase I from Geobacillus stearothermophilus by Site-Directed Mutagenesis at the Active Site. Biomed Res Int (2016) 0.75
A frameshift addition causes silencing of the delta-globin gene in an old world monkey, an anubis (Papio doguera). Nucleic Acids Res (1983) 0.75
Re-engineering the polymerase domain of Klenow fragment and evaluation of overproduction and purification strategies. Nucleic Acids Res (1993) 0.75
Purification and characterization of a DNA polymerase from the cyanobacterium Anacystis nidulans R2. Nucleic Acids Res (1990) 0.75
Isolation of Haemophilus influenzae genes that suppress Escherichia coli polA mutations. J Bacteriol (1987) 0.75
Dynamics of DNA polymerase I (Klenow fragment) under external force. J Mol Model (2012) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Estimation of the molecular weights of proteins by Sephadex gel-filtration. Biochem J (1964) 35.63
Enzymatic synthesis of deoxyribonucleic acid. XXVI. Physical and chemical studies of a homogeneous deoxyribonucleic acid polymerase. J Biol Chem (1969) 10.45
Thermal conversion of nonpriming deoxyribonucleic acid to primer. J Biol Chem (1959) 9.41
Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme. J Biol Chem (1962) 7.30
Enzymatic synthesis of deoxyribonucleic acid. XXV. Purification and properties of deoxyribonucleic acid polymerase induced by infection with phage T4. J Biol Chem (1968) 6.42
Peptides obtained by tryptic hydrolysis of performic acid-oxidized ribonuclease. J Biol Chem (1956) 5.88
Active center of DNA polymerase. Science (1969) 4.47
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEIC ACID. XV. PURIFICATION AND PROPERTIES OF A POLYMERASE FROM BACILLUS SUBTILIS. J Biol Chem (1964) 3.82
An active fragment of DNA polymerase produced by proteolytic cleavage. Biochem Biophys Res Commun (1969) 2.96
Enzymatic synthesis of deoxyribonucleic acid. XXX. Binding of triphosphates to deoxyribonucleic acid polymerase. J Biol Chem (1969) 2.80
Examination of the dissociation of multichain proteins in guanidine hydrochloride by membrane osmometry. Biochemistry (1968) 2.18
Subtilisin BPN. VII. Isolation of cyanogen bromide peptides and the complete amino acid sequence. J Biol Chem (1967) 1.89
Enzymatic synthesis of deoxyribonucleic acid. 28. The pyrophosphate exchange and pyrophosphorolysis reactions of deoxyribonucleic acid polymerase. J Biol Chem (1969) 1.64
Enzymatic synthesis of deoxyribonucleic acid. XXXI. Binding of deoxyribonucleic acid to deoxyribonucleic acid polymerase. J Biol Chem (1969) 1.53
DNA polymerase: evidence for multiple molecular species. Proc Natl Acad Sci U S A (1968) 1.16
Studies on the synthesis of deoxyribonucleic acid. I. Further purification and properties of the deoxyribonucleic acid polymerase induced by infection of Escherichia coli with bacteriophage T5. J Biol Chem (1968) 1.13
Enzymatic synthesis of deoxyribonucleic acid. XXVII. Chemical modifications of deoxyribonucleic acid polymerase. J Biol Chem (1969) 1.12
Two species of DNA polymerase isolated from Escherichia coli. Eur J Biochem (1967) 1.10
[The determination of the molecular weight of D-glyceraldehyde-3-phosphate dehydrogenase. On molecular weight determination in multi-component systems and under the influence of activators]. Hoppe Seylers Z Physiol Chem (1960) 0.98
The degradation of the B-chain of oxidized insulin by two subtilisins and their succinylated and N-carbamylated derivatives. C R Trav Lab Carlsberg (1968) 0.95
Proteolytic cleavage fo native DNA polymerase into two different catalytic fragments. Influence of assay condtions on the change of exonuclease activity and polymerase activity accompanying cleavage. Eur J Biochem (1971) 3.16
The N-terminal amino-acid sequences of DNA polymerase I from Escherichia coli and of the large and the small fragments obtained by a limited proteolysis. Eur J Biochem (1974) 1.67
Abundant amounts of diadenosine 5',5"'-P1,P4-tetraphosphate are present and releasable, but metabolically inactive, in human platelets. Biochem J (1982) 1.59
Some properties of partially purified mammalian adenosine kinase. J Biol Chem (1967) 1.18
Differential inhibition of RNA synthesis by actinomycin. Biochem Biophys Res Commun (1964) 0.88
Effect of monovalent cations on the activity of the DNA polymerase of Escherichia coli B. Eur J Biochem (1969) 0.86
3-Aminobenzamide stimulates unscheduled DNA synthesis and rejoining of strand breaks in human lymphocytes. Biochem Biophys Res Commun (1981) 0.81
Involvement of Escherichia coli DNA polymerase-I-associated 5' in equilibrium 3' exonuclease in excision-repair of UV-damaged DNA. Basic Life Sci (1975) 0.80
Net uptake of orthophosphate in Ehrlich ascites tumor cells in the presence of purine riboside may be rate limiting for the expansion of the pool of ribonucleotides. Biochim Biophys Acta (1994) 0.80
On the mechanism of inhibition by fluoride ions of the DNA polymerase reaction. Biochim Biophys Acta (1969) 0.80
The unborn and newborn child. I. Risk factors predicting complicated delivery in a general population of 4,102 women. Acta Obstet Gynecol Scand (1989) 0.80
The selective innervation of guinea-pig superior cervical ganglion cells by sprouts from intact preganglionic axons. J Physiol (1985) 0.78
Both hypoxanthine and adenosine stimulate DNA synthesis independently in serum-starved L cells treated with platelet protein. Proc Natl Acad Sci U S A (1983) 0.78
Different relationships between cellular adenosine or 3'-deoxyadenosine phosphorylation and cellular adenine ribonucleotide catabolism may be obtained. J Cell Physiol (1993) 0.78
Platelet-derived growth factor stimulates chemotaxis and nucleic acid synthesis in the protozoan Tetrahymena. Biochim Biophys Acta (1984) 0.77
Effect of 3'-amino-3'-deoxyadenosine on nucleic acid synthesis in Ehrlich ascites tumor cells. Mol Pharmacol (1968) 0.77
Antenatal and perinatal conditions correlated to handicap among 4-year-old children. Am J Perinatol (1989) 0.77
The rate of catabolism of dATP to deoxyadenosine during the growth of different cell lines in vitro. FEBS Lett (1992) 0.75
Iolation and charcterization of a DNA-binding non-histone protein from Tetrahymena pyriformis. Biochim Biophys Acta (1975) 0.75
The unborn and newborn child. II. Risk factors predicting perinatal morbidity and mortality in 4,138 infants. Acta Obstet Gynecol Scand (1989) 0.75
Which types of perinatal events are predictable? A look at a risk score model. Acta Obstet Gynecol Scand (1990) 0.75
Expansion of the cellular content of ribonucleoside triphosphates induces cell shrinkage and KCl loss in Ehrlich ascites tumor cells and in Chinese hamster ovary cells. Biochim Biophys Acta (1997) 0.75
Diagnosis of storage pool deficiency by determination of diadenosine 5', 5'''-P1,P4-tetraphosphate in whole blood. Thromb Res (1986) 0.75
Differential effect of N-carboxymethylisatoylation on the DNA polymerase activity, the 5' leads to 3'-exonuclease activity and the 3' leads to 5'-exonuclease activity of DNA polymerase I of Escherichia coli. Biochim Biophys Acta (1981) 0.75
On the mechanism of action of free purine bases on DNA synthesis in serum-starved L-cells treated with platelet extract. Arch Biochem Biophys (1985) 0.75