Published in Nucleic Acids Res on July 11, 1979
Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence. Proc Natl Acad Sci U S A (1980) 10.27
Directed mutagenesis of DNA cloned in filamentous phage: influence of hemimethylated GATC sites on marker recovery from restriction fragments. Nucleic Acids Res (1982) 5.72
Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function. Proc Natl Acad Sci U S A (1982) 4.64
Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA. Nucleic Acids Res (1981) 3.87
Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformation. Proc Natl Acad Sci U S A (1982) 3.12
Further improvements on the phosphotriester synthesis of deoxyribooligonucleotides and the oligonucleotide directed site-specific mutagenesis of E. coli lipoprotein gene. Nucleic Acids Res (1983) 2.05
Biological activities of EGF-receptor mutants with individually altered autophosphorylation sites. EMBO J (1988) 1.92
Oligonucleotide-directed mutagenesis of gene IX of bacteriophage M13. Nucleic Acids Res (1982) 1.29
Release of a phorbol ester-induced mitogenic block by mutation at Thr-654 of the epidermal growth factor receptor. Mol Cell Biol (1988) 1.25
Genetic control of capsid length in bacteriophage T4: DNA sequence analysis of petite and petite/giant mutants. J Virol (1987) 0.89
Construction and properties of a ribosome-binding site mutation in gene E of phi X174 bacteriophage. J Virol (1984) 0.83
Mutational mechanisms by which an inactive replication origin of bacteriophage M13 is turned on are similar to mechanisms of activation of ras proto-oncogenes. J Virol (1985) 0.83
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Nucleotide sequence of the rightward operator of phage lambda. Proc Natl Acad Sci U S A (1975) 56.75
The use of thin acrylamide gels for DNA sequencing. FEBS Lett (1978) 40.52
Reversal of bacteriophage T4 induced polynucleotide kinase action. Biochemistry (1973) 21.41
DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping. Nucleic Acids Res (1974) 19.42
Chromatography of 32P-labelled oligonucleotides on thin layers of DEAE-cellulose. Eur J Biochem (1969) 15.21
The nucleotide sequence of bacteriophage phiX174. J Mol Biol (1978) 13.55
Purification and further properties of single-strand-specific nuclease from Aspergillus oryzae. Eur J Biochem (1973) 13.54
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase. Biochemistry (1973) 11.45
Mutagenesis at a specific position in a DNA sequence. J Biol Chem (1978) 7.56
Overlapping genes in bacteriophage phiX174. Nature (1976) 4.35
Selective elimination of the exonuclease activity of the deoxyribonucleic acid polymerase from Escherichia coli B by limited proteolysis. Proc Natl Acad Sci U S A (1970) 4.25
Efficient correction of a mutation by use of chemically synthesized DNA. Proc Natl Acad Sci U S A (1978) 4.13
Proteolytic cleavage fo native DNA polymerase into two different catalytic fragments. Influence of assay condtions on the change of exonuclease activity and polymerase activity accompanying cleavage. Eur J Biochem (1971) 3.16
The base-pairing specificity of cellulose-pdT9. Nucleic Acids Res (1975) 3.11
Enzymatic synthesis of DNA, XXIV. Synthesis of infectious phage phi-X174 DNA. Proc Natl Acad Sci U S A (1967) 3.09
An active fragment of DNA polymerase produced by proteolytic cleavage. Biochem Biophys Res Commun (1969) 2.96
The sequence of a region of bacteriophage phiX174 DNA coding for parts of genes A and B. J Mol Biol (1977) 2.33
Mutagenesis during in vitro DNA synthesis. Proc Natl Acad Sci U S A (1978) 2.05
Recognition site of Escherichia coli B restriction enzyme on phi XsB1 and simian virus 40 DNAs: an interrupted sequence. Proc Natl Acad Sci U S A (1978) 1.51
Enzymatic synthesis of oligonucleotides of defined sequence: synthesis of a segment of yeast iso-1-cytochrome c gene. Proc Natl Acad Sci U S A (1977) 1.09
On the origin of bacteriophage phiX174 replicative form DNA replication. Virology (1976) 1.09
Lysis inhibition of phi-X174-, M12-, and Q-beta-infected Escherichia coli bacteria by magnesium ions. Biochim Biophys Acta (1969) 1.08
Enzymatic synthesis of oligodeoxyribonucleotides of defined sequence. J Biol Chem (1978) 1.02
DNA sequence of a region of the phi X174 genome coding for a ribosome binding site. Nature (1977) 0.82
Nucleotide sequence of bacteriophage phi X174 DNA. Nature (1977) 95.69
The minimal gene complement of Mycoplasma genitalium. Science (1995) 32.41
Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors. Methods Enzymol (1983) 17.47
Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. Curr Top Microbiol Immunol (1990) 16.31
Oligonucleotide-directed mutagenesis: a simple method using two oligonucleotide primers and a single-stranded DNA template. DNA (1984) 14.55
The nucleotide sequence of bacteriophage phiX174. J Mol Biol (1978) 13.55
Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA. Nucleic Acids Res (1982) 13.52
A general method for defining restriction enzyme cleavage and recognition sites. Methods Enzymol (1980) 13.26
Sequence of the gene for iso-1-cytochrome c in Saccharomyces cerevisiae. Cell (1979) 10.86
Specific cleavage analysis of mammalian mitochondrial DNA. Proc Natl Acad Sci U S A (1975) 9.65
Specific fragments of phi X174 deoxyribonucleic acid produced by a restriction enzyme from Haemophilus aegyptius, endonuclease Z. J Virol (1972) 8.22
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Lancet (2009) 7.96
Mutagenesis at a specific position in a DNA sequence. J Biol Chem (1978) 7.56
Report of the Committee on the Genetic Constitution of Chromosomes 7, 8 and 9. Cytogenet Cell Genet (1985) 7.28
The specific non-symmetrical sequence recognized by restriction endonuclease MboII. J Mol Biol (1980) 6.36
E-CELL: software environment for whole-cell simulation. Bioinformatics (1999) 6.29
Deletion mapping of sequences essential for in vivo transcription of the iso-1-cytochrome c gene. Proc Natl Acad Sci U S A (1981) 6.26
Specific endonuclease R fragments of bacteriophage phiX174 deoxyribonucleic acid. J Virol (1972) 5.98
The process of infection with bacteriophage phi-X174. X. Mutations in a phi-X Lysis gene. J Mol Biol (1966) 5.64
Environmental lead and children's intelligence: a systematic review of the epidemiological evidence. BMJ (1994) 5.55
The sequence of the DNAs coding for the mating-type loci of Saccharomyces cerevisiae. Cell (1981) 5.23
A position effect in the control of transcription at yeast mating type loci. Nature (1981) 5.23
Complete mutagenesis of the HIV-1 protease. Nature (1989) 5.16
The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence. Cell (1984) 5.10
The alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability of alcohol and drug modules in a clinical sample. Drug Alcohol Depend (1997) 5.10
Four mating-type genes control sexual differentiation in the fission yeast. EMBO J (1988) 5.00
Site-specific mutagenesis using synthetic oligodeoxyribonucleotide primers: II. In vitro selection of mutant DNA. Gene (1979) 4.99
The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons. Mol Cell Biol (1986) 4.83
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature (2000) 4.68
Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron (1999) 4.68
Maternal inheritance of mammalian mitochondrial DNA. Nature (1974) 4.46
Overlapping genes in bacteriophage phiX174. Nature (1976) 4.35
HIV-1 protease inhibitors. A review for clinicians. JAMA (1997) 4.34
Work system design for patient safety: the SEIPS model. Qual Saf Health Care (2006) 4.21
How biomedical investigators use library books. Bull Med Libr Assoc (1966) 4.20
The nucleotide sequence recognized by the Escherichia coli K12 restriction and modification enzymes. J Mol Biol (1979) 4.06
Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB. Diabetes (2001) 3.83
Report of the committee on the genetic constitution of chromosomes 9 and 10. Cytogenet Cell Genet (1989) 3.79
Genetic assay for small fragments of bacteriophage phi X174 deoxyribonucleic acid. J Virol (1971) 3.78
Isolation and sequence of the gene for iso-2-cytochrome c in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1980) 3.62
Expression and processing of the AIDS virus reverse transcriptase in Escherichia coli. Science (1987) 3.46
Undergraduate research. Genomics Education Partnership. Science (2008) 3.45
Identification and isolation of the yeast cytochrome c gene. Cell (1978) 3.39
The mapping and sequence determination of the single site in phiX174am3 replicative form DNA cleaved by restriction endonuclease Pst I. FEBS Lett (1976) 3.31
Tn554--a site-specific repressor-controlled transposon in Staphylococcus aureus. Nature (1979) 3.27
A determination of mutagen specificity in bacteria using nonsense mutants of bacteriophage T4. J Mol Biol (1967) 3.26
Prostate Testing for Cancer and Treatment (ProtecT) feasibility study. Health Technol Assess (2003) 3.25
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nat Genet (1999) 3.25
Mutations of the yeast SUP4 tRNATyr locus: transcription of the mutant genes in vitro. Cell (1980) 3.24
Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis. Proc Natl Acad Sci U S A (1989) 3.13
Master genes in mammalian repetitive DNA amplification. Trends Genet (1992) 3.11
The base-pairing specificity of cellulose-pdT9. Nucleic Acids Res (1975) 3.11
The Epstein-Barr virus BMLF1 promoter contains an enhancer element that is responsive to the BZLF1 and BRLF1 transactivators. J Virol (1989) 3.11
In vitro mutation analysis of the mating-type locus in yeast. Cell (1981) 3.09
Site-specific mutagenesis using synthetic oligodeoxyribonucleotide primers: I. Optimum conditions and minimum ologodeoxyribonucleotide length. Gene (1979) 3.05
Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients. Nat Genet (1994) 2.93
Characterization of a short, cis-acting DNA sequence which conveys cell cycle stage-dependent transcription in Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.91
Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis. Am J Med (1973) 2.88
Genetic Map of Bacteriophage phiX174. J Virol (1971) 2.84
Nucleotide sequence of the yeast alcohol dehydrogenase II gene. J Biol Chem (1983) 2.82
Structure of the 3' hairpin termini of four rodent parvovirus genomes: nucleotide sequence homology at origins of DNA replication. Cell (1979) 2.78
In vitro mutagenesis. Annu Rev Genet (1985) 2.72
Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol Cell Biol (1988) 2.70
Hormone replacement therapy and breast cancer: what are the facts? Med J Aust (1995) 2.66
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding. Nature (1982) 2.63
Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2+)-activated K+ channel from smooth muscle. J Biol Chem (1994) 2.62
Cleavage of HIV-1 gag polyprotein synthesized in vitro: sequential cleavage by the viral protease. AIDS Res Hum Retroviruses (1989) 2.62
The mechanisms of reovirus uncoating and gene activation in vivo. Virology (1972) 2.60
Treatment decision-making at the end of life: a survey of Australian doctors' attitudes towards patients' wishes and euthanasia. Med J Aust (1996) 2.59
Oligonucleotide-directed mutagenesis: a simple method using two oligonucleotide primers and a single-stranded DNA template. Methods Enzymol (1987) 2.59
Isolation and genetic localization of three phi-X174 promoter regions. Nat New Biol (1973) 2.55
DNA sequences of two yeast promoter-up mutants. Nature (1983) 2.50
Regional gene assignment of human porphobilinogen deaminase and esterase A4 to chromosome 11q23 leads to 11qter. Proc Natl Acad Sci U S A (1981) 2.50
How white and African Americans view their health and social problems. Different experiences, different expectations. JAMA (1995) 2.48
Psychiatric Research Interview for Substance and Mental Disorders (PRISM): reliability for substance abusers. Am J Psychiatry (1996) 2.47
Nucleotide sequence of salmon testes and salmon liver cytoplasmic initiator tRNA. Cell (1975) 2.46
Cryptosporidiosis in hospital patients with gastroenteritis. Am J Trop Med Hyg (1983) 2.45
The role of emotionality and regulation in children's social functioning: a longitudinal study. Child Dev (1995) 2.43
The DNA sequence and biological annotation of human chromosome 1. Nature (2006) 2.42
Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff. Mol Cell Biol (2000) 2.41