Published in J Immunol on June 01, 1970
X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect. J Exp Med (1975) 3.03
Radioresistance of the enhancing effect of cells from carrier-immunized mice in an in vitro primary immune response. Proc Natl Acad Sci U S A (1971) 2.79
The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J Exp Med (1978) 2.00
Immune response to a hapten coupled to a nonimmunogenic carrier. Influence of lipopolysaccharide. J Exp Med (1972) 1.95
Immunoglobulins on the surface of thymus-derived cells engaged in the initiation of a humoral immune response. J Exp Med (1971) 1.73
Selective priming of T cells by chemically altered cell antigens. J Exp Med (1972) 1.69
Mode of action of a supernatant activity from T-cell cultures that nonspecifically stimulates the humoral immune response. Proc Natl Acad Sci U S A (1974) 1.57
B-cell tolerance. II. Trinitrophenyl human gamma globulin-induced tolerance in adult and neonatal murine B cells responsive to thymus-dependent and independent forms of the same hapten. J Exp Med (1977) 1.57
Cell surface immunoglobulin. XX. Antibody responsiveness of subpopulations of B lymphocytes bearing different isotypes. J Exp Med (1977) 1.57
Regulation of the immune response. II. Qualitative and quantitative differences between thymus- and bone marrow-derived lymphocytes in the recognition of antigen. J Exp Med (1973) 1.57
B-lymphocytes activation by the Fc region of IgG. J Exp Med (1977) 1.51
Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance. J Exp Med (1976) 1.50
The role of H-2-linked genes in helper T-cell function. I. In vitro expression in B cells of immune response genes controlling helper T-cell activity. J Exp Med (1977) 1.49
Subclass-restricted IgG polyclonal antibody production in mice injected with lipid A-rich lipopolysaccharides. J Exp Med (1981) 1.48
Immunological adjuvants and the mechanism of cell cooperation. J Exp Med (1972) 1.42
On the number and nature of antigen-sensitive lymphocytes in the blood of delayed-hypersensitive human donors. J Exp Med (1971) 1.42
T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response. Immunology (1975) 1.39
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. J Exp Med (1977) 1.37
B-cell tolerance. III. Effect of papain-mediated cleavage of cell surface IgD on tolerance susceptibility of murine B cells. J Exp Med (1977) 1.32
Antigen-specific, H-2-restricted helper T cell hybridomas. J Exp Med (1982) 1.29
Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med (1971) 1.23
Changes in suppressor mechanisms during postnatal development in mice. J Exp Med (1978) 1.22
Immunological tolerance to a hapten. I. Induction and maintenance of tolerance to trinitrophenyl with trinitrobenzene sulfonic acid. J Exp Med (1973) 1.19
Direct blockade of antigen-reactive B lymphocytes by immune complexes. An 'off' signal for precursors of IgM-producing cells provided by the linkage of antigen-and Fc-receptors. Immunology (1978) 1.16
Virus-replicating T cells in the immune response of mice. I. Virus plaque assay of the lymphocytes reactive to sheep erythrocytes. J Exp Med (1977) 1.15
Antigen-specific induction and regulation of antibody synthesis in cultures of human peripheral blood mononuclear cells. Proc Natl Acad Sci U S A (1980) 1.13
Functional characteristics of Peyer's patch cells. III. Carrier priming of T cells by antigen feeding. J Exp Med (1975) 1.13
Age-dependent variations of antibody avidity. Immunology (1978) 1.13
Blocking of primary in vitro antibody responses to thymus-independent and thymus-dependent antigens with antiserum specific for IgM or IgD. Proc Natl Acad Sci U S A (1978) 1.10
Thymic requirement for cyclical idiotypic and reciprocal anti-idiotypic immune responses to a T-independent antigen. J Exp Med (1980) 1.06
Effect of lipid A-associated protein and lipid A on the expression of lipopolysaccharide activity. I. Immunological activity. Immunology (1980) 1.03
Virus-replicating T cells in the immune response of mice. II. Characterization of T cells capable of replicating vesicular stomatitis virus. J Exp Med (1978) 1.02
Definition of conditions that enable antigen-specific activation of the majority of isolated trinitrophenol-binding B cells. J Exp Med (1982) 1.01
Kinetics of humoral responsiveness in severe thermal injury. Ann Surg (1976) 0.97
Carrier-directed anti-hapten responses by B-cell subsets. J Exp Med (1977) 0.95
Regulation of the immune response. 3. Kinetic differences between thymus- and bone marrow- derived lymphocytes in the proliferative response to heterologous erythrocytes. J Exp Med (1973) 0.95
Effect of azathioprine on in vitro antibody response. Differential effect on B cells involved in thymus-dependent and independent responses. Clin Exp Immunol (1975) 0.95
T-cell helper response to antigens of Schistosoma mansoni in CBA mice. Clin Exp Immunol (1976) 0.93
Cellular and humoral immune responses in mice. II. Effect of intraperitoneal or subcutaneous injection of carrier of anti-hapten antibody and delayed hypersensitivity responses. Immunology (1975) 0.91
Cell interactions in the suppression of in vitro antibody responses. J Exp Med (1976) 0.89
Thymocytotoxic autoantibodies found in mice infected with Schistosoma japonicum. Infect Immun (1981) 0.89
The effect of adult thymectomy upon helper function in Xenopus laevis, the South African clawed toad. Immunology (1979) 0.88
Effect of carrier priming on antibody avidity in the in vivo and in vitro immune response. Immunology (1977) 0.88
Isolation and identification of a biologically active peptide derived from the CH3 domain of human IgG1. Proc Natl Acad Sci U S A (1982) 0.86
B-lymphocyte activation with an extract of Nocardia brasiliensis. Infect Immun (1979) 0.84
A dichotomy between the expression of IgD on B cells and its requirement for triggering such cells with two T-independent antigens. J Exp Med (1979) 0.83
The 'intrinsic adjuvanticity' and immunogenicity of trinitrophenylated lipopolysaccharide. Immunology (1975) 0.83
The induction of hapten-specific immunological tolerance and immunity in B lymphocytes. VI. Differential tolerance susceptibility in adult spleen as a function of B-cell maturation level. J Exp Med (1979) 0.82
The potentiality of antibody-producing cells. I Bispecific cell occurrence in double stimulated cultures of syngeneic or allogeneic spleen cells of the mouse. Immunology (1975) 0.80
Lymphokine-induced suppressor B cells. Immunology (1982) 0.79
An in vivo primary response to 2,4,6-trinitrophenyl substituted erythrocytes. Immunology (1973) 0.79
T cell regulation of polyclonal B cell responsiveness. III. Overt T helper and latent T suppressor activities from distinct subpopulations of unstimulated splenic T cells. J Exp Med (1981) 0.78
Differential effects of glucocorticosteroids on the functions of helper and suppressor T lymphocytes. Proc Natl Acad Sci U S A (1981) 0.78
Effect of synthetic thymic humoral factor (THF-gamma 2) on T cell activities in immunodeficient ageing mice. Clin Exp Immunol (1992) 0.78
In vitro immune response of spleen cells from mice genetically selected for high or low antibody production. Immunology (1978) 0.75
Further study on the humoral response of a highly-purified spleen-derived immunosuppressive peptide (SDIP). Immunology (1981) 0.75
Rapid loss of feedback suppressor T-cell activity after priming in vivo. Immunology (1986) 0.75
Immunological activities of purified preparations of enterobacterial common antigen. Infect Immun (1982) 0.75
Antibody response to a protein antigen (ovalbumin) in dissociated spleen cell cultures from primed mice. Evidence for a suppressive effect of antigen. Immunology (1973) 0.75
Immunization of dissociated spleen cell cultures from normal mice. J Exp Med (1967) 30.93
Immunization of normal mouse spleen cell suspensions in vitro. Science (1966) 6.47
Cell populations and cell proliferation in the in vitro response of normal mouse spleen to heterologous erythrocytes. Analysis by the hot pulse technique. J Exp Med (1967) 5.78
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. I. Characterization of the inhibitory cell activity. J Exp Med (1972) 3.80
Activated antigen-specific CD8+ T cells persist in the lungs following recovery from respiratory virus infections. J Immunol (2001) 3.68
Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen. Proc Natl Acad Sci U S A (1981) 3.28
Helper T-cell subsets: phenotype, function and the role of lymphokines in regulating their development. Immunol Rev (1991) 3.21
Cellular events in the immune response : analysis and in vitro response of mouse spleen cell populations separated by differential flotation in albumin gradients. J Exp Med (1968) 3.12
Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles. J Exp Med (1994) 3.02
Radioresistance of the enhancing effect of cells from carrier-immunized mice in an in vitro primary immune response. Proc Natl Acad Sci U S A (1971) 2.79
Unequal death in T helper cell (Th)1 and Th2 effectors: Th1, but not Th2, effectors undergo rapid Fas/FasL-mediated apoptosis. J Exp Med (1997) 2.59
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J Exp Med (1983) 2.56
Delayed hypersensitivity: is the same population of thymus-derived cells responsible for cellular immunity reactions and the carrier effect? Immunol Commun (1972) 2.42
Immune response restoration with macrophage culture supernatants. Science (1971) 2.37
Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. II. Evidence for separate stimulatory and inhibitory cells. J Exp Med (1973) 2.33
Separate signals for the initiation of proliferation and differentiation in the b cell response to antigen. Transplant Rev (1975) 2.32
Suppressor T cells. Transplant Rev (1975) 2.28
Production of a B cell growth-promoting activity, (DL)BCGF, from a cloned T cell line and its assay on the BCL1 B cell tumor. J Exp Med (1982) 2.22
Differential stimulation of precursor cells and carrier-specific thymus-derived cell activity in the in vivo reponse to heterologous erythrocytes in mice. J Immunol (1972) 2.21
Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection. J Exp Med (1999) 2.09
Naive, effector, and memory CD8 T cells in protection against pulmonary influenza virus infection: homing properties rather than initial frequencies are crucial. J Immunol (1999) 1.99
Cell components in the immune response. II. Cell attachment separation of immune cells. Cell Immunol (1970) 1.94
Inhibition of spleen cell DNA synthesis by autologous macrophages. J Immunol (1966) 1.84
Induction of B cell differentiation by T cell factors. I. Stimulation of IgM secretion by products of a T cell hybridoma and a T cell line. J Immunol (1981) 1.73
Immunoglobulins on the surface of thymus-derived cells engaged in the initiation of a humoral immune response. J Exp Med (1971) 1.73
The Lyt phenotype of a long-term allospecific T cell line. Both helper and killer activities to IA are mediated by Ly-1 cells. Eur J Immunol (1981) 1.72
Radioresistance of cells responsible for delayed hypersensitivity reactions in the mouse. J Immunol (1975) 1.72
Cell components in the immune response. 3. Neonatal thymectomy: restoration in culture. Cell Immunol (1970) 1.66
Further studies of the stimulation of DNA synthesis in cultures of spleen cell suspensions by homologous cells in inbred strains of mice and rats. J Exp Med (1965) 1.63
Production of interferon-gamma by influenza hemagglutinin-specific CD8 effector T cells influences the development of pulmonary immunopathology. Am J Pathol (2001) 1.63
Type 1 and type 2: a fundamental dichotomy for all T-cell subsets. Curr Opin Immunol (1996) 1.60
Xenogeneic human anti-mouse T cell responses are due to the activity of the same functional T cell subsets responsible for allospecific and major histocompatibility complex-restricted responses. J Exp Med (1983) 1.56
Continuously proliferating allospecific T cells. I. Specificity of cooperation with allogeneic B cells in the humoral antibody response to sheep erythrocytes. J Exp Med (1979) 1.54
Localization of antigenic determinants in the polypeptide chains of collagen. Science (1969) 1.51
Antigen receptor molecules: inhibition by antiserum against kappa light chains. Science (1970) 1.46
The significance of T-B collaboration across haplotype barriers. Cold Spring Harb Symp Quant Biol (1977) 1.44
The role of IL4 and IL5: characterization of a distinct helper T cell subset that makes IL4 and IL5 (Th2) and requires priming before induction of lymphokine secretion. Immunol Rev (1988) 1.44
T cell replacing factors in the B cell response to antigen. Immunol Rev (1982) 1.44
In vivo persistence of CD8 polarized T cell subsets producing type 1 or type 2 cytokines. J Immunol (1998) 1.43
Spleen cell proliferation in response to homologous antigens studied in congenic resistant strains of mice. J Exp Med (1966) 1.39
Separation of helper and suppressor T lymphocytes. II. Ly phenotypes and lack of DNA synthesis requirement for the generation of concanavalin A helper and suppressor cells. J Exp Med (1977) 1.39
Separation of helper and suppressor T lymphocytes on a ficoll velocity sedimentation gradient. J Exp Med (1976) 1.36
Cell components in the immune response. IV. Relationships and possible interactions. Cell Immunol (1970) 1.36
Symposium on in vitro studies of the immune response. II. Significance of the reaction of lymphoid cells to homologous tissue. Bacteriol Rev (1966) 1.36
Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response. J Immunol (1977) 1.30
The properties of plaque-forming cells from autoimmune and normal strains of mice with specificity for autologous erythrocyte antigens. J Immunol (1975) 1.25
Regulation of the immune response. I. Differential effect of passively administered antibody on the thymus-derived and bone marrow-derived lymphocytes. J Exp Med (1971) 1.23
Production of Con A-induced helper T cell replacing factor requires a T cell and an Ia-positive non-T cells. J Immunol (1980) 1.23
In vitro studies of immunological responses of lymphoid cells. Adv Immunol (1967) 1.20
Stimulation of DNA synthesis in cultures of mouse spleen cell suspensions by bovine transferrin. Exp Cell Res (1969) 1.18
B cell stimulatory factor 1 (interleukin 4) is sufficient for the proliferation and differentiation of lectin-stimulated cytolytic T lymphocyte precursors. J Exp Med (1987) 1.17
Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection. J Exp Med (1980) 1.14
Partial purification and characterization of a BCGFII from EL4 culture supernatants. J Immunol (1984) 1.13
Alloantigen-induced T helper activity. I. Minimal genetic differences necessary to induce a positive allogeneic effect. J Immunol (1978) 1.10
Ly phenotypes and MHC recognition: the allohelper that recognizes K or D is a mature Ly123 cell. J Immunol (1979) 1.06
Fine specificity mapping of two allospecific T cell lines: recognition of private specificities in the H-2 IA subregion. Eur J Immunol (1981) 1.04
Therapeutic effects of tumor-reactive type 1 and type 2 CD8+ T cell subpopulations in established pulmonary metastases. J Immunol (1999) 1.03
Competition between concanavalin A-induced stimulatory and inhibitory effects in the in vitro immune response to antigen. J Exp Med (1975) 1.02
Role of effector cell-derived IL-4, IL-5, and perforin in early and late stages of type 2 CD8 effector cell-mediated tumor rejection. J Immunol (2001) 1.01
Antibody synthesis in vitro, a marker of B cell differentiation. J Immunol Methods (1980) 0.99
Evidence that Con A induces cytotoxicity in the same subclass of T cells as does alloimmunization. J Immunol (1977) 0.98
In vitro induction of specific unresponsiveness against the 2,4,6-trinitrophenyl determinant. I. The induction of unresponsiveness. J Immunol (1974) 0.98
Evidence for two distinct activation states available to B lymphocytes. J Immunol (1984) 0.98
Improving geometric model construction for blood flow modeling. IEEE Eng Med Biol Mag (1999) 0.97
Toward an objective classification of cells in the immune system. Proc Natl Acad Sci U S A (1988) 0.96
Regulation of the immune response T-cell interactions. CRC Crit Rev Immunol (1982) 0.96
CD28, IL-2-independent costimulatory pathways for CD8 T lymphocyte activation. J Immunol (1999) 0.96
Alloreactivity, the development of the T cell repertoire and the understanding of T cell function. Immunol Rev (1978) 0.95
Cellular cooperation in hapten-carrier responses in the newt, Triturus viridescens. Cell Immunol (1973) 0.94
Relative perforin- and Fas-mediated lysis in T1 and T2 CD8 effector populations. J Immunol (1995) 0.93
Cell components in the immune response. I. Gradient separation of immune cells. Cell Immunol (1970) 0.93
The humoral response of mouse spleen cells to two types of sheep erythrocytes. I. Genetic control of the response to H and L SRBC. J Immunol (1975) 0.91
Immunopotentiating role of IFN-gamma in early and late stages of type 1 CD8 effector cell-mediated tumor rejection. Clin Immunol (2001) 0.91
The humoral response of mouse spleen cells to two types of sheep erythrocytes. III. A new VH region marker. J Immunol (1975) 0.91
The structure of the mouse immunoglobulin in gamma 3 membrane gene segment. Nucleic Acids Res (1983) 0.90
Purification and partial sequence analysis of murine B cell growth factor II (interleukin 5). J Immunol (1987) 0.90
Negative allogeneic effects in vitro. II. Mapping of histocompatibility differences leading to allosuppression. J Immunol (1977) 0.89
A monoclonal T cell-replacing activity can act directly on B cells to enhance clonal expansion. J Exp Med (1982) 0.89
An attempt to assess the overall diversity of murine T cells using two-dimensional gel electrophoresis. Eur J Immunol (1984) 0.89
Consequences of the direct interaction of helper T cells with B cells presenting antigen. Immunol Rev (1987) 0.89
Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for unresponsiveness in the B cells. Eur J Immunol (1974) 0.89
Changes in the protein pattern of murine B cells after mitogenic stimulation. Eur J Immunol (1984) 0.88
Type 1 and type 2 CD8+ effector T cell subpopulations promote long-term tumor immunity and protection to progressively growing tumor. J Immunol (2000) 0.88
Frequency of allogeneic helper T cells responding to whole H-2 differences and to an H-2K difference alone. J Immunol (1979) 0.87
An approach to molecular analysis of T-cell clones by two-dimensional gel electrophoresis: is there interclonal and intraclonal heterogeneity? Clin Chem (1984) 0.86
Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion. J Immunol (1988) 0.86
Antigen suppression of the in vitro development of plaque-forming cells to autologous erythrocyte antigens. J Immunol (1975) 0.86
Characterization of the target antigen of F1 anti-parent cytotoxic lympholysis: analysis of the spontaneous in vitro F1 cytotoxic T lymphocytes. J Immunol (1980) 0.85
Induction of the H-2 D antigen during B cell activation. J Immunol (1989) 0.84
Precursor cell division during the immune response in vitro: antigen-induced and "spontaneous" antibody-forming cells. Eur J Immunol (1973) 0.84
Suppressor T cells in the regulation of the immune response. J Reticuloendothel Soc (1975) 0.83
Primary in vitro cytotoxic response of F1 T lymphocytes against parental antigens. J Immunol (1979) 0.82
Separation of helper and suppressor T lymphocytes. III. Positive and negative effects of mixed lymphocyte reaction-activated T cells. J Immunol (1978) 0.82
Independent analysis of T helper and T killer cell function in young and old NZB mice. J Immunol (1978) 0.82
The allogeneic effect: bystander effect in the primary immune response in vitro. Eur J Immunol (1974) 0.81
Monoclonal antibody that distinguishes between a phosphorylated, beta 2-microglobulin-associated, and a free, nonphosphorylated, chain of MHC class I. J Immunol (1993) 0.81