Published in Arch Biochem Biophys on August 01, 1979
Cloning and expression of cDNA for rat heme oxygenase. Proc Natl Acad Sci U S A (1985) 2.18
Function and induction of the microsomal heme oxygenase. Mol Cell Biochem (1983) 1.31
Participation of altered upstream stimulatory factor in the induction of rat heme oxygenase-1 by cadmium. Nucleic Acids Res (1996) 0.82
Calcium-dependent changes in potassium currents in guinea-pig coronary artery smooth muscle cells after acute cobalt loading in vivo. Pflugers Arch (2004) 0.75
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 12.66
Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature (2000) 3.41
AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem (2001) 3.32
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14. Nature (1999) 3.20
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J Clin Invest (1987) 2.70
Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets. Proc Natl Acad Sci U S A (1985) 2.59
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes Dev (2000) 2.15
Phenotypic stability of adult rat hepatocytes in primary monolayer culture. Ann N Y Acad Sci (1980) 1.96
Human apolipoprotein E mRNA. cDNA cloning and nucleotide sequencing of a new variant. J Biol Chem (1984) 1.78
Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix. J Cell Physiol (1988) 1.76
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 1.75
Identification of an inducible form of cytochrome P-450 in human liver. Proc Natl Acad Sci U S A (1985) 1.62
Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin. Proc Natl Acad Sci U S A (1985) 1.61
Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. J Clin Invest (1989) 1.59
Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p. Biochemistry (1985) 1.57
Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver. Proc Natl Acad Sci U S A (1986) 1.57
Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. Mol Pharmacol (1996) 1.55
Treatment of chlordecone (Kepone) toxicity with cholestyramine. Results of a controlled clinical trial. N Engl J Med (1978) 1.47
Comparative toxicology of chlordecone (Kepone) in humans and experimental animals. Annu Rev Pharmacol Toxicol (1982) 1.45
Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR. Br J Pharmacol (1999) 1.38
Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P-450 by a nonclassical receptor mechanism. J Biol Chem (1984) 1.37
Drug metabolism in adult rat hepatocytes in primary monolayer culture. Gastroenterology (1977) 1.35
Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile. J Biol Chem (1980) 1.31
Down regulation of insulin receptors in primary cultures of adult rat hepatocytes in monolayer. Endocrinology (1978) 1.27
Characterization of human liver cytochromes P-450 involved in theophylline metabolism. Drug Metab Dispos (1992) 1.24
Effect of cobalt on synthesis of heme and cytochrome P-450 in the liver. Studies of adult rat hepatocytes in primary monolayer culture and in vivo. J Biol Chem (1976) 1.24
Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase. Biochemistry (1990) 1.21
A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids. J Biol Chem (1995) 1.21
Degradation of endogenous hepatic heme by pathways not yielding carbon monoxide. Studies in normal rat liver and in primary hepatocyte culture. J Clin Invest (1980) 1.21
Collagen formation by the hepatocyte in primary monolayer culture and in vivo. Science (1983) 1.21
Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture. J Biol Chem (1986) 1.20
Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes. Drug Metab Dispos (1995) 1.19
Structure and expression of the human apolipoprotein A-IV gene. J Biol Chem (1987) 1.17
A cDNA encoding the calcitonin gene-related peptide type 1 receptor. J Biol Chem (1996) 1.17
Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents. Mol Pharmacol (1982) 1.16
Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver. Pharmacogenetics (1994) 1.14
Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils. J Leukoc Biol (1997) 1.12
Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes. Hepatology (1993) 1.11
Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene. J Biol Chem (1988) 1.11
Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo. Biochemistry (1986) 1.10
Changes in the concentration of seven forms of cytochrome P-450 in primary cultures of adult rat hepatocytes. Mol Pharmacol (1985) 1.07
Distribution and excretion of chlordecone (Kepone) in the rat. Drug Metab Dispos (1978) 1.06
Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes. Toxicol Appl Pharmacol (1993) 1.04
Coinduction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents. Mol Pharmacol (1989) 1.04
Cyp3A regulation: from pharmacology to nuclear receptors. Drug Metab Dispos (2001) 1.03
In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes. Antimicrob Agents Chemother (1990) 1.03
Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. J Biol Chem (2000) 1.01
Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clin Pharmacol Ther (1992) 1.00
The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III. J Biol Chem (1986) 1.00
Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes. Proc Natl Acad Sci U S A (1992) 0.99
Stimulation of de novo synthesis of cytochrome P-450 by phenobarbital in primary nonproliferating cultures of adult rat hepatocytes. Proc Natl Acad Sci U S A (1982) 0.98
Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1. Proc Natl Acad Sci U S A (1990) 0.98
Regulation of cytochrome P-450b/e and P-450p gene expression by growth hormone in adult rat hepatocytes cultured on a reconstituted basement membrane. J Biol Chem (1990) 0.96
On computer-assisted analysis of biological sequences: proline punctuation, consensus sequences, and apolipoprotein repeats. J Lipid Res (1986) 0.96
Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E. J Biol Chem (1986) 0.96
Induction of cytochrome P-450 by pregnenolone-16 alpha-carbonitrile in primary monolayer cultures of adult rat hepatocytes and in a cell-free translation system. J Biol Chem (1981) 0.95
Suitability of primary monolayer cultures of adult rat hepatocytes for studies of cholesterol and bile acid metabolism. J Biol Chem (1985) 0.95
Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol. Clin Pharmacol Ther (1992) 0.95
Hepatocellular phenotype in vitro is influenced by biophysical features of the collagenous substratum. Hepatology (1991) 0.95
Reduction in the body content of DDE in the Mongolian gerbil treated with sucrose polyester and caloric restriction. Toxicol Appl Pharmacol (1988) 0.94
1,3-Diarylindan-2-carboxylic acids, potent and selective non-peptide endothelin receptor antagonists. J Med Chem (1994) 0.93
Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. J Clin Invest (1993) 0.93
Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins. J Biol Chem (1985) 0.93
Induction of digitoxigenin monodigitoxoside UDP-glucuronosyltransferase activity by glucocorticoids and other inducers of cytochrome P-450p in primary monolayer cultures of adult rat hepatocytes and in human liver. J Biol Chem (1986) 0.92
Liver structure and function in patients poisoned with chlordecone (Kepone). Gastroenterology (1980) 0.91
Studies of the formation and relase of glycerolipids by primary monolayer cultures of adult rat hepatocytes. Biochim Biophys Acta (1977) 0.90
Adenosine triphosphate citrate lyase mediates hypocitraturia in rats. J Clin Invest (1996) 0.90
Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver. Arch Biochem Biophys (1989) 0.89
Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat. Biochem J (1987) 0.88
Cholestyramine: use as a new therapeutic approach for chlordecone (kepone) poisoning. Science (1978) 0.88
Collagen synthesis by the hepatocyte: studies in primary cultures of parenchymal cells from adult rat liver. Coll Relat Res (1981) 0.87
Inhibition by cycloheximide of degradation of cytochrome P-450 in primary cultures of adult rat liver parenchymal cells and in vivo. Biochem J (1979) 0.85
Corticosterone 6 beta-hydroxylase in A6 epithelia: a steroid-inducible cytochrome P-450. Am J Physiol (1990) 0.84
Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats. J Clin Invest (1987) 0.84
Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. Mol Pharmacol (1990) 0.84
Identification of a reduced form of chlordecone (Kepone) in human stool. Bull Environ Contam Toxicol (1978) 0.84
Purification and characterization of chlordecone reductase from human liver. J Biol Chem (1986) 0.84
Nonpeptide tachykinin receptor antagonists: I. Pharmacological and pharmacokinetic characterization of SB 223412, a novel, potent and selective neurokinin-3 receptor antagonist. J Pharmacol Exp Ther (1997) 0.83
Expression of multiple forms of cytochrome P450 mRNAs in primary cultures of rat hepatocytes maintained on matrigel. Mol Pharmacol (1993) 0.83
Identification of a cytochrome P-450 in human fetal liver related to glucocorticoid-inducible cytochrome P-450HLp in the adult. Biochem Pharmacol (1988) 0.83
Synthesis and degradation of 3-methylcholanthrene-inducible cytochromes P-450 and their mRNAs in primary monolayer cultures of adult rat hepatocytes. Arch Biochem Biophys (1985) 0.83
Divergent effects of cycloheximide on the induction of class II and class III cytochrome P450 mRNAs in cultures of adult rat hepatocytes. Arch Biochem Biophys (1990) 0.83
Localization of collagen prolyl hydroxylase to the hepatocyte. Studies in primary monolayer cultures of parenchymal cells from adult rat liver. Exp Cell Res (1979) 0.83
Absence of negative feedback control of bile acid biosynthesis in cultured rat hepatocytes. J Biol Chem (1985) 0.83
Identification of a small-molecule, nonpeptide macrophage scavenger receptor antagonist. J Pharmacol Exp Ther (1999) 0.82
Benzo[a]pyrene differentially alters mitochondrial and nuclear DNA synthesis in primary hepatocyte cultures. Res Commun Chem Pathol Pharmacol (1983) 0.82
Ascorbic acid deficiency and cytochrome P-450 in adult rat hepatocytes in primary monolayer culture. Arch Biochem Biophys (1979) 0.82
Cloning and functional characterization of the human vasoactive intestinal peptide (VIP)-2 receptor. Biochem Biophys Res Commun (1995) 0.82
Expression of five forms of microsomal cytochrome P-450 in primary cultures of rabbit hepatocytes treated with various classes of inducers. Biochem Pharmacol (1987) 0.82
Role of heme in phenobarbital induction of cytochromes P450 and 5-aminolevulinate synthase in cultured rat hepatocytes maintained on an extracellular matrix. Arch Biochem Biophys (1990) 0.82
Preferential binding of chlordecone to the protein and high density lipoprotein fractions of plasma from humans and other species. J Toxicol Environ Health (1982) 0.81
Tyrosine kinase growth factor receptors but not seven-membrane-spanning receptors or phorbol esters activate mitogen-activated protein kinase in rat hepatocytes. Hepatology (1995) 0.81
Rapid loss of delta-aminolevulinic acid dehydratase activity in primary cultures of adult rat hepatocytes: a new model of zinc deficiency. Life Sci (1982) 0.81
Evaluation of chlordecone in a two-stage model of hepatocarcinogenesis: a significant sex difference in the hepatocellular carcinoma incidence. Carcinogenesis (1989) 0.80
Purification and characterization of aldo-keto reductases from gerbil liver: immunochemical evidence for related proteins in other mammalian species. Arch Biochem Biophys (1986) 0.80