Published in Biochim Biophys Acta on November 24, 1977
Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. Biochem J (1988) 0.90
Antipsychotic drug action on SREBPs-related lipogenesis and cholesterogenesis in primary rat hepatocytes. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.90
The effect of acute and chronic ethanol intake on hepatic glycerolipid biosynthesis in the hamster. J Clin Invest (1979) 0.88
Selective channelling of arachidonic and linoleic acids into glycerolipids of rat hepatocytes in primary culture. Biochem J (1988) 0.80
Effects of acetaldehyde on hepatocyte glycerol uptake and cell size: implication of aquaporin 9. Alcohol Clin Exp Res (2011) 0.79
Effects of hormones on changes in cytochrome P-450, prolyl hydroxylase, and glycerol phosphate acyltransferase in primary monolayer cultures of parenchymal cells from adult rat liver. Yale J Biol Med (1979) 0.75
Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. Ann Intern Med (1989) 4.07
Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature (2000) 3.41
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. J Clin Invest (1987) 2.70
Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes Dev (2000) 2.15
Phenotypic stability of adult rat hepatocytes in primary monolayer culture. Ann N Y Acad Sci (1980) 1.96
Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix. J Cell Physiol (1988) 1.76
Fluoxetine treatment of depression caused by interferon-alpha. Am J Gastroenterol (1993) 1.62
Identification of an inducible form of cytochrome P-450 in human liver. Proc Natl Acad Sci U S A (1985) 1.62
Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. J Clin Invest (1989) 1.59
Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p. Biochemistry (1985) 1.57
Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver. Proc Natl Acad Sci U S A (1986) 1.57
Trans-species gene transfer for analysis of glucocorticoid-inducible transcriptional activation of transiently expressed human CYP3A4 and rabbit CYP3A6 in primary cultures of adult rat and rabbit hepatocytes. Mol Pharmacol (1996) 1.55
Liver structure and function in print workers exposed to toluene. J Occup Med (1988) 1.53
Treatment of chlordecone (Kepone) toxicity with cholestyramine. Results of a controlled clinical trial. N Engl J Med (1978) 1.47
Comparative toxicology of chlordecone (Kepone) in humans and experimental animals. Annu Rev Pharmacol Toxicol (1982) 1.45
Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P-450 by a nonclassical receptor mechanism. J Biol Chem (1984) 1.37
Drug metabolism in adult rat hepatocytes in primary monolayer culture. Gastroenterology (1977) 1.35
Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile. J Biol Chem (1980) 1.31
Down regulation of insulin receptors in primary cultures of adult rat hepatocytes in monolayer. Endocrinology (1978) 1.27
Characterization of human liver cytochromes P-450 involved in theophylline metabolism. Drug Metab Dispos (1992) 1.24
Effect of cobalt on synthesis of heme and cytochrome P-450 in the liver. Studies of adult rat hepatocytes in primary monolayer culture and in vivo. J Biol Chem (1976) 1.24
Isolation and characterization of cloned cDNAs encoding human liver chlordecone reductase. Biochemistry (1990) 1.21
Alcoholic hepatitis. Natural history and evaluation of prednisolone therapy. Ann Intern Med (1971) 1.21
A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids. J Biol Chem (1995) 1.21
Degradation of endogenous hepatic heme by pathways not yielding carbon monoxide. Studies in normal rat liver and in primary hepatocyte culture. J Clin Invest (1980) 1.21
Collagen formation by the hepatocyte in primary monolayer culture and in vivo. Science (1983) 1.21
An enzymatic explanation for dietary induced alterations in hepatic glycerolipid metabolism. Biochim Biophys Acta (1974) 1.20
Glycerolipid synthesis in rat adipose tissue. II. Properties and distribution of phosphatidate phosphatase. J Lipid Res (1973) 1.20
Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture. J Biol Chem (1986) 1.20
Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes. Drug Metab Dispos (1995) 1.19
Phosphatidate phosphohydrolase and the regulation of glycerolipid biosynthesis. Biochem Soc Trans (1977) 1.18
Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents. Mol Pharmacol (1982) 1.16
Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver. Pharmacogenetics (1994) 1.14
Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes. Hepatology (1993) 1.11
Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo. Biochemistry (1986) 1.10
Glycerolipid formation from sn-glycerol-3-phosphate by rat liver cell fractions. The role of phosphatidate phosphohydrolase. Biochim Biophys Acta (1974) 1.08
Changes in the concentration of seven forms of cytochrome P-450 in primary cultures of adult rat hepatocytes. Mol Pharmacol (1985) 1.07
Distribution and excretion of chlordecone (Kepone) in the rat. Drug Metab Dispos (1978) 1.06
Two enzymes of serine metabolism in rat liver and hepatomas. Cancer Res (1970) 1.04
Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes. Toxicol Appl Pharmacol (1993) 1.04
Coinduction of multiple hepatic cytochrome P-450 proteins and their mRNAs in rats treated with imidazole antimycotic agents. Mol Pharmacol (1989) 1.04
Effects of diet on hepatic triglyceride synthesis. J Clin Invest (1968) 1.04
Cyp3A regulation: from pharmacology to nuclear receptors. Drug Metab Dispos (2001) 1.03
In vitro effect of fluoroquinolones on theophylline metabolism in human liver microsomes. Antimicrob Agents Chemother (1990) 1.03
Inhibition of monoacylglycerophosphate formation by chlorophenoxyisobutyrate and -benzalbutyrate. J Biol Chem (1972) 1.02
Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clin Pharmacol Ther (1992) 1.00
Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes. Proc Natl Acad Sci U S A (1992) 0.99
Stimulation of de novo synthesis of cytochrome P-450 by phenobarbital in primary nonproliferating cultures of adult rat hepatocytes. Proc Natl Acad Sci U S A (1982) 0.98
Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1. Proc Natl Acad Sci U S A (1990) 0.98
Glycerolipid biosynthesis in rat adipose tissue. I. Properties and distribution of glycerophosphate acyltransferase and effect of divalent cations on neutral lipid formation. J Lipid Res (1973) 0.96
Regulation of cytochrome P-450b/e and P-450p gene expression by growth hormone in adult rat hepatocytes cultured on a reconstituted basement membrane. J Biol Chem (1990) 0.96
Induction of cytochrome P-450 by pregnenolone-16 alpha-carbonitrile in primary monolayer cultures of adult rat hepatocytes and in a cell-free translation system. J Biol Chem (1981) 0.95
A review of studies on the mode of action of clofibrate and betabenzalbutyrate. Lipids (1972) 0.95
Hepatocellular phenotype in vitro is influenced by biophysical features of the collagenous substratum. Hepatology (1991) 0.95
Suitability of primary monolayer cultures of adult rat hepatocytes for studies of cholesterol and bile acid metabolism. J Biol Chem (1985) 0.95
Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol. Clin Pharmacol Ther (1992) 0.95
Reduction in the body content of DDE in the Mongolian gerbil treated with sucrose polyester and caloric restriction. Toxicol Appl Pharmacol (1988) 0.94
Triacylglycerol biosynthesis in the adipose tissue of the obese-hyperglycaemic mouse. Biochem J (1976) 0.94
Changes in cytochromes P-450, 2E1, 2B1, and 4A, and phospholipases A and C in the intragastric feeding rat model for alcoholic liver disease: relationship to dietary fats and pathologic liver injury. Alcohol Clin Exp Res (1994) 0.93
Studies of rat liver microsomal diglyceride acyltransferase and cholinephosphotransferase using microsomal-bound substrate: effects of high fructose intake. J Lipid Res (1975) 0.93
Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. J Clin Invest (1993) 0.93
Response of hyperlipoproteinemia to cholestyramine resin. JAMA (1968) 0.93
Induction of digitoxigenin monodigitoxoside UDP-glucuronosyltransferase activity by glucocorticoids and other inducers of cytochrome P-450p in primary monolayer cultures of adult rat hepatocytes and in human liver. J Biol Chem (1986) 0.92
Inhibition of hepatic triglyceride formation by clofibrate. J Clin Invest (1971) 0.91
Treatment of alcoholic hepatitis with encephalopathy. Comparison of prednisolone with caloric supplements. Gastroenterology (1978) 0.91
Liver structure and function in patients poisoned with chlordecone (Kepone). Gastroenterology (1980) 0.91
2-phosphoglyceric acid phosphatase: identification and properties of the beef-liver enzyme. Biochim Biophys Acta (1965) 0.90
The acute effects of streptozotocin-induced diabetes on rat liver glycerolipid biosynthesis. Biochim Biophys Acta (1981) 0.89
Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver. Arch Biochem Biophys (1989) 0.89
Serine biosynthesis in rat liver. Regulation of enzyme concentration by dietary factors. J Biol Chem (1966) 0.89
The effect of acute and chronic ethanol intake on hepatic glycerolipid biosynthesis in the hamster. J Clin Invest (1979) 0.88
Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat. Biochem J (1987) 0.88
Cholestyramine: use as a new therapeutic approach for chlordecone (kepone) poisoning. Science (1978) 0.88
The effect of high-carbohydrate diets on liver triglyceride formation in the rat. J Clin Invest (1973) 0.87
Effects of ethanol on hepatic microsomal drug-metabolizing enzymes in the rat. Biochem Pharmacol (1975) 0.87
Collagen synthesis by the hepatocyte: studies in primary cultures of parenchymal cells from adult rat liver. Coll Relat Res (1981) 0.87
A quantitative morphological analysis of ethanol effect upon rat liver. Gastroenterology (1972) 0.86
Developmental regulation of the plant mitochondrial matrix located HSP70 chaperone and its role in protein import. FEBS Lett (1997) 0.86
Inhibition by cycloheximide of degradation of cytochrome P-450 in primary cultures of adult rat liver parenchymal cells and in vivo. Biochem J (1979) 0.85
Corticosterone 6 beta-hydroxylase in A6 epithelia: a steroid-inducible cytochrome P-450. Am J Physiol (1990) 0.84
Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. Mol Pharmacol (1990) 0.84
The effect of ethanol on glycerolipid biosynthesis by primary monolayer cultures of adult rat hepatocytes. Biochim Biophys Acta (1979) 0.84
Purification and characterization of chlordecone reductase from human liver. J Biol Chem (1986) 0.84
Purification of a human liver cytochrome P-450 immunochemically related to several cytochromes P-450 purified from untreated rats. J Clin Invest (1987) 0.84
Hypolipidemic activity of in vitro inhibitors of hepatic and intestinal sn-glycerol-3-phosphate acyltransferase and phosphatidate phosphohydrolase. Atherosclerosis (1977) 0.84
Identification of a reduced form of chlordecone (Kepone) in human stool. Bull Environ Contam Toxicol (1978) 0.84
Induction of hepatic heme oxygenase activity by bromobenzene. Arch Biochem Biophys (1979) 0.83
Divergent effects of cycloheximide on the induction of class II and class III cytochrome P450 mRNAs in cultures of adult rat hepatocytes. Arch Biochem Biophys (1990) 0.83
The formation of monoacylglycerophosphate from sn-glycerol 3-phosphate by a rat liver particulate preparation. J Biol Chem (1970) 0.83
Regulatory phenomena in mammalian serine metabolism. Adv Enzyme Regul (1967) 0.83