Published in J Exp Med on September 01, 1965
Endocytosis and the recycling of plasma membrane. J Cell Biol (1983) 10.24
The isolation and selected properties of blood monocytes. J Exp Med (1966) 7.78
Membrane flow during pinocytosis. A stereologic analysis. J Cell Biol (1976) 7.20
Pinocytosis in fibroblasts. Quantitative studies in vitro. J Cell Biol (1974) 5.15
The in vitro differentiation of mononuclear phagocytes. V. The formation of macrophage lysosomes. J Exp Med (1966) 4.84
Cellular hypersensitivity and cellular immunity in the pathogensis of tuberculosis: specificity, systemic and local nature, and associated macrophage enzymes. Bacteriol Rev (1968) 4.25
Characterization of a lymphocyte factor which alters macrophage functions. J Exp Med (1973) 3.98
The uptake and digestion of iodinated human serum albumin by macrophages in vitro. J Exp Med (1967) 3.70
The uptake, storage, and intracellular hydrolysis of carbohydrates by macrophages. J Exp Med (1969) 3.66
The in vitro differentiation of mononuclear phagocytes. IV. The ultrastructure of macrophage differentiation in the peritoneal cavity and in culture. J Exp Med (1966) 3.41
In vitro induction of lysosomal enzymes by phagocytosis. J Exp Med (1970) 3.11
Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation. J Cell Biol (1981) 3.02
Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes. J Cell Biol (1984) 2.71
The fate of peptides pinocytosed by macrophages in vitro. J Exp Med (1969) 2.49
Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis. J Cell Biol (1983) 2.49
Cholesterol metabolism in the macrophage. 3. Ingestion and intracellular fate of cholesterol and cholesterol esters. J Exp Med (1972) 1.92
Cavitary tuberculosis produced in rabbits by aerosolized virulent tubercle bacilli. Infect Immun (1996) 1.68
Fate of hemoglobin pincytosed by macrophages in vitro. J Cell Biol (1968) 1.57
Killing and lysis of gram-negative bacteria through the synergistic effect of hydrogen peroxide, ascorbic acid, and lysozyme. J Bacteriol (1969) 1.51
Endocytosis: a review of mechanisms and plasma membrane dynamics. Biochem J (1983) 1.33
Autoradiographic evidence for the impermeability of mouse peritoneal macrophages to tritiated streptomycin. J Bacteriol (1967) 1.27
Differential and sequential delivery of fluorescent lysosomal probes into phagosomes in mouse peritoneal macrophages. J Cell Biol (1987) 1.24
Structure-function relationships in the adipose cell. II. Pinocytosis and factors influencing its activity in the isolated adipose cell. J Cell Biol (1970) 1.14
Purine excretion by mouse peritoneal macrophages lacking adenosine deaminase activity. Proc Natl Acad Sci U S A (1979) 1.11
Selective release of lysosomal hydrolases from phagocytic cells by cytochalasin B. Biochem J (1973) 1.04
The course and nature of acinar cell death following pancreatic ligation in the guinea pig. Am J Pathol (1975) 1.01
Zymosan-induced glycerylprostaglandin and prostaglandin synthesis in resident peritoneal macrophages: roles of cyclo-oxygenase-1 and -2. Biochem J (2006) 0.97
Zanvil Alexander Cohn 1926-1993. J Exp Med (1994) 0.91
A sensitive assay for cellular hypersensitivity based on the uptake of radioactive colloidal gold. Immunology (1974) 0.85
Blood feeding induces hemocyte proliferation and activation in the African malaria mosquito, Anopheles gambiae Giles. J Exp Biol (2013) 0.85
Hg2 plus-induced kidney necrosis. Subcellular localization and structure-linked lysosomal enzyme changes. Am J Pathol (1970) 0.81
Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine. Biochemistry (2008) 0.79
THE DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES. MORPHOLOGY, CYTOCHEMISTRY, AND BIOCHEMISTRY. J Exp Med (1965) 21.86
The isolation and properties of the specific cytoplasmic granules of rabbit polymorphonuclear leucocytes. J Exp Med (1960) 21.07
Isothiocyanate compounds as fluorescent labeling agents for immune serum. Am J Pathol (1959) 15.60
THE PARTICULATE HYDROLASES OF MACROPHAGES. I. COMPARATIVE ENZYMOLOGY, ISOLATION, AND PROPERTIES. J Exp Med (1963) 8.79
THE IN VITRO DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES. II. THE INFLUENCE OF SERUM ON GRANULE FORMATION, HYDROLASE PRODUCTION, AND PINOCYTOSIS. J Exp Med (1965) 7.97
THE IN VITRO DIFFERENTIATION OF MONONUCLEAR PHAGOCYTES. I. THE INFLUENCE OF INHIBITORS AND THE RESULTS OF AUTORADIOGRAPHY. J Exp Med (1965) 4.91
The in vitro uptake of fluorescein labelled plasma proteins. I. Mature cells. C R Trav Lab Carlsberg (1960) 2.70
Electron microscopy of HeLa cells after the ingestion of colloidal gold. J Biophys Biochem Cytol (1957) 2.42
The uptake of radiocolloids by macrophages in vitro; a kinetic analysis with radioactive colloidal gold. J Gen Physiol (1956) 1.42
The origin and kinetics of mononuclear phagocytes. J Exp Med (1968) 14.96
Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med (1973) 13.88
Endocytosis. Annu Rev Biochem (1977) 11.42
Endocytosis and the recycling of plasma membrane. J Cell Biol (1983) 10.24
The enzymatic iodination of the red cell membrane. J Cell Biol (1972) 8.62
Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J Exp Med (1979) 8.32
The isolation and selected properties of blood monocytes. J Exp Med (1966) 7.78
Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro. J Exp Med (1974) 7.58
In vitro synthesis and secretion of lysozyme by mononuclear phagocytes. J Exp Med (1974) 7.43
Membrane flow during pinocytosis. A stereologic analysis. J Cell Biol (1976) 7.20
The interaction of soluble horseradish peroxidase with mouse peritoneal macrophages in vitro. J Cell Biol (1972) 6.64
Identification of a novel cell type in peripheral lymphoid organs of mice. 3. Functional properties in vivo. J Exp Med (1974) 6.60
Increased superoxide anion production by immunologically activated and chemically elicited macrophages. J Exp Med (1978) 6.50
Activation of mononuclear phagocytes: fact, fancy, and future. J Immunol (1978) 6.22
Externally disposed plasma membrane proteins. I. Enzymatic iodination of mouse L cells. J Cell Biol (1975) 5.82
Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity. J Exp Med (1979) 5.38
Pinocytosis in fibroblasts. Quantitative studies in vitro. J Cell Biol (1974) 5.15
The regulation of pinocytosis in mouse macrophages. I. Metabolic requirements as defined by the use of inhibitors. J Exp Med (1966) 5.10
The structure and function of monocytes and macrophages. Adv Immunol (1968) 5.06
The in vitro differentiation of mononuclear phagocytes. V. The formation of macrophage lysosomes. J Exp Med (1966) 4.84
Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages. J Exp Med (1983) 4.68
The separation, long-term cultivation, and maturation of the human monocyte. J Exp Med (1977) 4.46
Hydrogen peroxide metabolism in human monocytes during differentiation in vitro. J Clin Invest (1981) 4.46
Induction of macrophage plasminogen activator by endotoxin stimulation and phagocytosis: evidence for a two-stage process. J Exp Med (1974) 4.45
Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med (1991) 4.43
Studies of the cell surface of mouse dendritic cells and other leukocytes. J Exp Med (1981) 4.36
The macrophage as an effector cell. N Engl J Med (1980) 4.30
Trypanosoma cruzi: in vitro induction of macrophage microbicidal activity. J Exp Med (1978) 4.29
The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells. Bull World Health Organ (1972) 4.25
The regulation of pinocytosis in mouse macrophages. II. Factors inducing vesicle formation. J Exp Med (1967) 4.17
Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. N Engl J Med (1986) 4.05
Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes. J Exp Med (1980) 3.88
Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates. J Exp Med (1979) 3.72
The uptake and digestion of iodinated human serum albumin by macrophages in vitro. J Exp Med (1967) 3.70
The uptake, storage, and intracellular hydrolysis of carbohydrates by macrophages. J Exp Med (1969) 3.66
Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide. J Exp Med (1979) 3.61
The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin. J Exp Med (1987) 3.61
A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J Exp Med (1989) 3.58
Effects of concanavalin A on mouse peritoneal macrophages. I. Stimulation of endocytic activity and inhibition of phago-lysosome formation. J Exp Med (1974) 3.52
The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes. N Engl J Med (1982) 3.52
Macrophage oxygen-dependent antimicrobial activity. III. Enhanced oxidative metabolism as an expression of macrophage activation. J Exp Med (1980) 3.43
The in vitro differentiation of mononuclear phagocytes. IV. The ultrastructure of macrophage differentiation in the peritoneal cavity and in culture. J Exp Med (1966) 3.41
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules. Proc Natl Acad Sci U S A (1985) 3.31
In vitro induction of lysosomal enzymes by phagocytosis. J Exp Med (1970) 3.11
Plasma membrane synthesis in the macrophage following phagocytosis of polystyrene latex particles. J Biol Chem (1972) 3.10
Identification of a novel cell type in peripheral lymphoid organs of mice. IV. Identification and distribution in mouse spleen. J Exp Med (1975) 3.03
Regulation of arachidonic acid metabolites in macrophages. J Exp Med (1980) 3.00
The pinocytic rate of activated macrophages. J Exp Med (1975) 2.97
Macrophage oxygen-dependent antimicrobial activity. I. Susceptibility of Toxoplasma gondii to oxygen intermediates. J Exp Med (1979) 2.93
Selective iodination and polypeptide composition of pinocytic vesicles. J Cell Biol (1980) 2.91
Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages. J Cell Biol (1980) 2.83
Mouse spleen lymphoblasts generated in vitro. Recovery in high yield and purity after floatation in dense bovine plasma albumin solutions. J Exp Med (1978) 2.75
The membrane proteins of the vacuolar system. II. Bidirectional flow between secondary lysosomes and plasma membrane. J Cell Biol (1980) 2.69
Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus. Proc Natl Acad Sci U S A (1980) 2.53
The macrophage. Int Rev Cytol (1973) 2.52
The selective inhibition of macrophage phagocytic receptors by anti-membrane antibodies. J Exp Med (1972) 2.51
Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections. Proc Natl Acad Sci U S A (1989) 2.50
The fate of peptides pinocytosed by macrophages in vitro. J Exp Med (1969) 2.49
Prostaglandin synthesis by macrophages requires a specific receptor-ligand interaction. Proc Natl Acad Sci U S A (1980) 2.49
Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis. J Cell Biol (1983) 2.49
The membrane proteins of the vacuolar system I. Analysis of a novel method of intralysosomal iodination. J Cell Biol (1980) 2.48
The interaction of particulate horseradish peroxidase (HRP)-anti HRP immune complexes with mouse peritoneal macrophages in vitro. J Cell Biol (1972) 2.48
Neutrophil-activating protein 1/interleukin 8 stimulates the binding activity of the leukocyte adhesion receptor CD11b/CD18 on human neutrophils. J Exp Med (1990) 2.42
Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature (1986) 2.41
The induction of macrophage spreading: role of coagulation factors and the complement system. J Exp Med (1976) 2.41
Externally disposed plasma membrane proteins. II. Metabolic fate of iodinated polypeptides of mouse L cells. J Cell Biol (1975) 2.39
Aggregation of complement receptors on human neutrophils in the absence of ligand. J Cell Biol (1987) 2.38
Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell (1986) 2.38
Liver macrophages in murine listeriosis. Cell-mediated immunity is correlated with an influx of macrophages capable of generating reactive oxygen intermediates. J Exp Med (1985) 2.37
Bacterial lipopolysaccharides prime macrophages for enhanced release of arachidonic acid metabolites. J Exp Med (1986) 2.34
The regulation of pinocytosis in mouse macrophages. IV. The immunological induction of pinocytic vesicles, secondary lysosomes, and hydrolytic enzymes. J Exp Med (1967) 2.29
Mycobacterium leprae antigen-induced suppression of T cell proliferation in vitro. J Immunol (1987) 2.27
Isolation and characterization of the human pulmonary surfactant apoprotein gene. Nature (1985) 2.27
Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures. J Exp Med (1983) 2.24
5'-Nucleotidase activity of mouse peritoneal macrophages. I. Synthesis and degradation in resident and inflammatory populations. J Exp Med (1976) 2.21
The alveolar macrophage. J Appl Physiol (1985) (1986) 2.21
Stimulus-dependent myristoylation of a major substrate for protein kinase C. Nature (1988) 2.21
The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities. Science (1986) 2.21
Properties of the major outer membrane protein from Neisseria gonorrhoeae incorporated into model lipid membranes. Proc Natl Acad Sci U S A (1983) 2.20
Cellular responses to the intradermal injection of recombinant human gamma-interferon in lepromatous leprosy patients. Am J Pathol (1987) 2.18
Vesicle fusion and formation at the surface of pinocytic vacuoles in macrophages. J Cell Biol (1968) 2.15
Autophagic vacuoles produced in vitro. I. Studies on cultured macrophages exposed to chloroquine. J Cell Biol (1968) 2.15
Influence of delayed immune reactions on human epidermal keratinocytes. Proc Natl Acad Sci U S A (1986) 2.11
Murine Kupffer cells. Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates. J Exp Med (1985) 2.03
Response of endocytosis to altered fatty acyl composition of macrophage phospholipids. Proc Natl Acad Sci U S A (1977) 2.01
Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor. Proc Natl Acad Sci U S A (1987) 1.96
Functional assembly of gap junction conductance in lipid bilayers: demonstration that the major 27 kd protein forms the junctional channel. Cell (1987) 1.94
Dynamics of leukotriene C production by macrophages. J Exp Med (1980) 1.93
Cholesterol metabolism in the macrophage. 3. Ingestion and intracellular fate of cholesterol and cholesterol esters. J Exp Med (1972) 1.92
Autophagic vacuoles produced in vitro. II. Studies on the mechanism of formation of autophagic vacuoles produced by chloroquine. J Cell Biol (1968) 1.91
Characterization of a membrane pore-forming protein from Entamoeba histolytica. J Exp Med (1982) 1.85
The increase in intracellular free calcium associated with IgG gamma 2b/gamma 1 Fc receptor-ligand interactions: role in phagocytosis. Proc Natl Acad Sci U S A (1984) 1.83
Fc-receptor variants of a mouse macrophage cell line. Proc Natl Acad Sci U S A (1979) 1.80
Peroxidase-mediated mammalian cell cytotoxicity. J Exp Med (1973) 1.77
Distribution and turnover of Langerhans cells during delayed immune responses in human skin. J Exp Med (1987) 1.74
Defective production of monocyte-activating cytokines in lepromatous leprosy. J Exp Med (1984) 1.74
Secretion of leukotriene C and other arachidonic acid metabolites by macrophages challenged with immunoglobulin E immune complexes. J Exp Med (1982) 1.73
Tumor cell anti-oxidant defenses. Inhibition of the glutathione redox cycle enhances macrophage-mediated cytolysis. J Exp Med (1981) 1.71
Macrophage membrane potential changes associated with gamma 2b/gamma 1 Fc receptor-ligand binding. Proc Natl Acad Sci U S A (1983) 1.70
Regulation of arachidonic acid metabolism by macrophage activation. J Exp Med (1982) 1.69