Published in N Engl J Med on September 11, 1980
Secretory products of macrophages. J Clin Invest (1987) 10.33
Expression and secretion of type beta transforming growth factor by activated human macrophages. Proc Natl Acad Sci U S A (1987) 6.76
Antibiotic entry into human polymorphonuclear leukocytes. Antimicrob Agents Chemother (1982) 3.62
Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy. Am J Pathol (1991) 2.92
Multiple biological activities of human recombinant interleukin 1. J Clin Invest (1986) 2.16
Granulomatous inflammation--a review. J Clin Pathol (1983) 2.15
Spontaneous expression of the c-sis gene and release of a platelet-derived growth factorlike molecule by human alveolar macrophages. J Clin Invest (1986) 1.80
Function and regulation of a murine macrophage-specific IgG Fc receptor, Fc gamma R-alpha. J Exp Med (1988) 1.72
IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers. J Clin Invest (2008) 1.71
Macrophage membrane potential changes associated with gamma 2b/gamma 1 Fc receptor-ligand binding. Proc Natl Acad Sci U S A (1983) 1.70
Human arterial wall cells secrete factors that are chemotactic for monocytes. Proc Natl Acad Sci U S A (1983) 1.64
Mouse macrophage Fc receptor for IgG gamma 2b/gamma 1 in artificial and plasma membrane vesicles functions as a ligand-dependent ionophore. Proc Natl Acad Sci U S A (1983) 1.64
Role of platelets and fibrin in the healing sequence: an in vivo study of angiogenesis and collagen synthesis. Ann Surg (1982) 1.62
Intracellular antimicrobial activity in the absence of interferon-gamma: effect of interleukin-12 in experimental visceral leishmaniasis in interferon-gamma gene-disrupted mice. J Exp Med (1997) 1.59
The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes. Proc Natl Acad Sci U S A (1993) 1.57
Human monocyte-endothelial cell interaction in vitro. Proc Natl Acad Sci U S A (1985) 1.54
Interaction of human leukocytes and Entamoeba histolytica. Killing of virulent amebae by the activated macrophage. J Clin Invest (1985) 1.49
Alveolar macrophages release an insulin-like growth factor I-type molecule. J Clin Invest (1988) 1.46
Activation-induced apoptosis in human macrophages: developmental regulation of a novel cell death pathway by macrophage colony-stimulating factor and interferon gamma. J Exp Med (1995) 1.42
Th1 CD4+ lymphocytes delete activated macrophages through the Fas/APO-1 antigen pathway. Proc Natl Acad Sci U S A (1995) 1.40
Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes. A possible mechanism of foam cell formation. J Exp Med (1988) 1.34
Chronic inflammatory bowel disease--increased plasminogen activator secretion by mononuclear phagocytes. Clin Exp Immunol (1982) 1.33
Inhibitors of monocyte responses to chemotaxins are present in human cancerous effusions and react with monoclonal antibodies to the P15(E) structural protein of retroviruses. J Clin Invest (1981) 1.31
A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury. J Neurosci (1992) 1.30
Relative contribution of leukotriene B4 to the neutrophil chemotactic activity produced by the resident human alveolar macrophage. J Clin Invest (1987) 1.28
Interaction of Legionella micdadei with human monocytes. Infect Immun (1984) 1.26
Lipoprotein lipase secretion by human monocyte-derived macrophages. J Clin Invest (1982) 1.26
Natural and recombinant interferons inhibit epithelial cell invasion by Shigella spp. Infect Immun (1986) 1.26
Nonphagocytic clearance of Staphylococcus aureus from murine lungs. Infect Immun (1982) 1.23
Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations. Am J Pathol (1987) 1.20
Lipoprotein lipase secretion by human monocytes and rabbit alveolar macrophages in culture. Proc Natl Acad Sci U S A (1982) 1.13
In vitro inhibition of murine macrophage migration by Bordetella pertussis lymphocytosis-promoting factor. Infect Immun (1984) 1.12
Effects of Histoplasma capsulatum on murine macrophage functions: inhibition of macrophage priming, oxidative burst, and antifungal activities. Infect Immun (1989) 1.10
Modulation of fibronectin gene expression in human mononuclear phagocytes. J Clin Invest (1987) 1.09
Stimulated arachidonate metabolism during foam cell transformation of mouse peritoneal macrophages with oxidized low density lipoprotein. J Clin Invest (1988) 1.09
Ionic channels in murine macrophages. J Cell Biol (1987) 1.08
Human erythroid burst-forming units. Growth in vitro is dependent on monocytes, but not T lymphocytes. J Clin Invest (1981) 1.07
Cartilage ultrastructure after high pressure freezing, freeze substitution, and low temperature embedding. I. Chondrocyte ultrastructure--implications for the theories of mineralization and vascular invasion. J Cell Biol (1984) 1.06
Histiocytosis X. Purified (T6+) cells from bone granuloma produce interleukin 1 and prostaglandin E2 in culture. J Clin Invest (1986) 1.01
Neurotrophic factors regulate cathepsin S in macrophages and microglia: A role in the degradation of myelin basic protein and amyloid beta peptide. Mol Med (1999) 1.00
African trypanosomiasis alters prostaglandin production by murine peritoneal macrophages. Clin Exp Immunol (1984) 1.00
Complement-subcomponent-C1-inhibitor synthesis by human monocytes. Biochem J (1985) 0.99
Antioxidants can prevent cerebral malaria in Plasmodium berghei-infected mice. Br J Exp Pathol (1989) 0.99
Characterization of a human blood monocyte subset with low peroxidase activity. J Clin Invest (1983) 0.96
Immune response to Nocardia brasiliensis antigens in an experimental model of actinomycetoma in BALB/c mice. Infect Immun (1999) 0.95
Murine peritoneal macrophages support murine cytomegalovirus replication. Infect Immun (1983) 0.95
Staphylococcal clearance and pulmonary macrophage function during influenza infection. Infect Immun (1982) 0.92
Zanvil Alexander Cohn 1926-1993. J Exp Med (1994) 0.91
Enhancement of inflammatory reactions in a non-immunological air pouch model in rats. Br J Exp Pathol (1989) 0.90
Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ. J Exp Clin Cancer Res (2014) 0.89
Comparison of the neovascular effects of stimulated macrophages and neutrophils in autologous rabbit corneas. Am J Pathol (1985) 0.88
Complement-mediated binding of monocytes to intermediate filaments in vitro. Am J Pathol (1983) 0.87
Monocyte chemoattractants in pigeon aortic atherosclerosis. Am J Pathol (1987) 0.87
Effect of interferon on chemiluminescence and hydroxyl radical production in murine macrophages stimulated by PMA. Immunology (1985) 0.87
Ingestion of Giardia lamblia trophozoites by human mononuclear phagocytes. Infect Immun (1987) 0.86
Macrophages: progress and problems. Clin Exp Immunol (1981) 0.85
Establishment of long-term monocyte suspension cultures from normal human peripheral blood. J Exp Med (1982) 0.85
Chemiluminescence of asbestos-activated macrophages. Br J Exp Pathol (1984) 0.85
The chemiluminescent response of human phagocytic cells to mineral dusts. Br J Exp Pathol (1985) 0.84
Activation of jird (Meriones unguiculatus) macrophages by the filarial parasite Brugia pahangi. Infect Immun (1984) 0.84
Inability of tumour cells to elicit the respiratory burst in cytotoxic, activated macrophages. Immunology (1982) 0.84
Collagen biosynthesis. Environ Health Perspect (1984) 0.84
In vitro effect of (3-amino-1-hydroxypropylidene)-1,1-bisphosphonic acid (APD) on the function of mononuclear phagocytes in lymphocyte proliferation. Immunology (1982) 0.83
Lysozyme as a measure of cellular dynamics in the lesions of leprosy. Br J Exp Pathol (1985) 0.83
Diminished activity of tartrate resistant acid phosphatase in alveolar macrophages from patients with active sarcoidosis. Thorax (1988) 0.83
Effects of ethanol and acetaldehyde on phagocytic functions. Arch Dermatol Res (1985) 0.83
Phagocytes, toxic oxygen metabolites and inflammatory bowel disease: implications for treatment. Ann R Coll Surg Engl (1990) 0.82
Pulmonary alveolar macrophages from patients with active sarcoidosis express type IV collagenolytic proteinase. An enzymatic mechanism for influx of mononuclear phagocytes at sites of disease activity. J Clin Invest (1989) 0.81
Species-related innate resistance to Schistosoma mansoni. Role of mononuclear phagocytes in schistosomula killing in vitro. J Clin Invest (1983) 0.81
Selective induction of phospholipase D1 in pathogen-activated human monocytes. Biochem J (2001) 0.81
Monocyte superoxide anion production in rheumatoid arthritis: preliminary evidence for enhanced rates of superoxide anion production by monocytes from patients receiving penicillamine, sodium aurothiomalate and corticosteroids. Ann Rheum Dis (1984) 0.81
Association of basal-lamina defects with epidermal and dermal T6-positive cells: evidence of Langerhans-cell migration. Arch Dermatol Res (1985) 0.80
Alveolar macrophage dysfunction in malignant lung tumours. Thorax (1984) 0.80
Analysis of lymphocyte subsets of bone marrow in patients with rheumatoid arthritis by two colour immunofluorescence and flow cytometry. Ann Rheum Dis (1990) 0.80
Activation of bovine monocytes and neutrophils by the Bb fragment of complement factor B: demonstration by the uptake of 3H-deoxyglucose. Can J Vet Res (1990) 0.80
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. Clin Exp Nephrol (2014) 0.79
Effects of human immunodeficiency virus sera and macrophage supernatants on mesangial cell proliferation and matrix synthesis. Am J Pathol (1993) 0.79
Effects of inhibitors of tumoricidal activity upon schistosomulum killing by activated macrophages. Infect Immun (1987) 0.79
Mononuclear phagocytes. BMJ (1989) 0.79
Primary in vitro plaque-forming cell response to DAGG-Ficoll: LPS-induced enhancement mediated by interleukin-1. Immunology (1984) 0.78
Bb fragment of bovine complement factor B: stimulation of the oxidative burst in bovine monocytes. Can J Vet Res (1990) 0.78
The 95000-Mr gelatin-binding protein in human serum and plasma. Biochem J (1985) 0.78
Fragment Bb of bovine complement factor B: stimulatory effect on the microbicidal activity of bovine monocytes. Can J Vet Res (1990) 0.77
Modulation of pulmonary clearance of bacteria by antioxidants. Infect Immun (1985) 0.77
Suppressor cell activity of human alveolar macrophages in interstitial lung diseases. Clin Exp Immunol (1988) 0.77
Complement components in relation to macrophage function. Agents Actions (1983) 0.77
Lack of biological significance of in vitro Brugia malayi microfilarial cytotoxicity mediated by Propionibacterium acnes ("Corynebacterium parvum")-and Mycobacterium bovis BCG-activated macrophages. Infect Immun (1986) 0.77
The biology of acute transplant rejection. Ann Surg (1991) 0.77
Relationship between macrophage infiltration and epidermopoiesis in delayed-type hypersensitivity. Arch Dermatol Res (1988) 0.75
Natural macrophage cytotoxicity against Trichomonas vaginalis is mediated by soluble lytic factors. Infect Immun (1983) 0.75
Modulation of Microglial Cell Fcγ Receptor Expression Following Viral Brain Infection. Sci Rep (2017) 0.75
Suppression of the neutral protease activity of macrophages treated with asbestos in vitro. Environ Health Perspect (1983) 0.75
Collagenase production by human mononuclear cells in culture: inhibition by gold containing compounds and other antirheumatic agents. Ann Rheum Dis (1986) 0.75
Regulation of the metabolism of lipoprotein-proteoglycan complexes in human monocyte-derived macrophages. Biochem J (1994) 0.75
Crystal-phagocyte interaction in calcinosis interstitialis. Arch Dermatol Res (1984) 0.75
Functional droplets that recognize, collect, and transport debris on surfaces. Sci Adv (2016) 0.75
Analysis of effects of lipopolysaccharide and interferon on murine macrophages: modulation of elastase secretion in vitro. Infect Immun (1985) 0.75
Opportunistic infections and impaired cell-mediated immune responses in patients with the acquired immune deficiency syndrome. Trans Am Clin Climatol Assoc (1984) 0.75
Interaction of lipoproteins with the artery wall. Drugs (1988) 0.75
The origin and kinetics of mononuclear phagocytes. J Exp Med (1968) 14.96
Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J Immunol (1988) 14.21
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med (1983) 14.08
Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J Exp Med (1973) 13.88
Endocytosis. Annu Rev Biochem (1977) 11.42
Secretory products of macrophages. J Clin Invest (1987) 10.33
Endocytosis and the recycling of plasma membrane. J Cell Biol (1983) 10.24
The enzymatic iodination of the red cell membrane. J Cell Biol (1972) 8.62
Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J Exp Med (1979) 8.32
Alterations of macrophage functions by mediators from lymphocytes. J Exp Med (1971) 7.95
Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc Natl Acad Sci U S A (1997) 7.90
The isolation and selected properties of blood monocytes. J Exp Med (1966) 7.78
Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp Med (1989) 7.72
Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro. J Exp Med (1974) 7.58
In vitro synthesis and secretion of lysozyme by mononuclear phagocytes. J Exp Med (1974) 7.43
An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction. N Engl J Med (1981) 7.35
Membrane flow during pinocytosis. A stereologic analysis. J Cell Biol (1976) 7.20
Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res (1991) 6.99
The interaction of soluble horseradish peroxidase with mouse peritoneal macrophages in vitro. J Cell Biol (1972) 6.64
Identification of a novel cell type in peripheral lymphoid organs of mice. 3. Functional properties in vivo. J Exp Med (1974) 6.60
Increased superoxide anion production by immunologically activated and chemically elicited macrophages. J Exp Med (1978) 6.50
Activation of mononuclear phagocytes: fact, fancy, and future. J Immunol (1978) 6.22
Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine. J Clin Invest (1983) 5.88
Externally disposed plasma membrane proteins. I. Enzymatic iodination of mouse L cells. J Cell Biol (1975) 5.82
Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering. J Exp Med (1977) 5.44
Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity. J Exp Med (1979) 5.38
Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J Exp Med (1988) 5.16
Pinocytosis in fibroblasts. Quantitative studies in vitro. J Cell Biol (1974) 5.15
The regulation of pinocytosis in mouse macrophages. I. Metabolic requirements as defined by the use of inhibitors. J Exp Med (1966) 5.10
The structure and function of monocytes and macrophages. Adv Immunol (1968) 5.06
The in vitro differentiation of mononuclear phagocytes. V. The formation of macrophage lysosomes. J Exp Med (1966) 4.84
Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. Ann Intern Med (1984) 4.73
Specific antimononuclear phagocyte monoclonal antibodies. Application to the purification of dendritic cells and the tissue localization of macrophages. J Exp Med (1983) 4.68
The separation, long-term cultivation, and maturation of the human monocyte. J Exp Med (1977) 4.46
Hydrogen peroxide metabolism in human monocytes during differentiation in vitro. J Clin Invest (1981) 4.46
Induction of macrophage plasminogen activator by endotoxin stimulation and phagocytosis: evidence for a two-stage process. J Exp Med (1974) 4.45
Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med (1991) 4.43
Studies of the cell surface of mouse dendritic cells and other leukocytes. J Exp Med (1981) 4.36
Trypanosoma cruzi: in vitro induction of macrophage microbicidal activity. J Exp Med (1978) 4.29
The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cells. Bull World Health Organ (1972) 4.25
The regulation of pinocytosis in mouse macrophages. II. Factors inducing vesicle formation. J Exp Med (1967) 4.17
Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy. N Engl J Med (1986) 4.05
Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein. Proc Natl Acad Sci U S A (1991) 4.01
Characterization of a lymphocyte factor which alters macrophage functions. J Exp Med (1973) 3.98
The in vitro differentiation of mononuclear phagocytes. 3. The reversibility of granule and hydrolytic enzyme formation and the turnover of granule constituents. J Exp Med (1965) 3.92
Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes. J Exp Med (1980) 3.88
Activation of mouse peritoneal macrophages in vitro and in vivo by interferon-gamma. J Immunol (1985) 3.85
Impaired production of lymphokines and immune (gamma) interferon in the acquired immunodeficiency syndrome. N Engl J Med (1984) 3.73
Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates. J Exp Med (1979) 3.72
Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic. Clin Infect Dis (2000) 3.72
The uptake and digestion of iodinated human serum albumin by macrophages in vitro. J Exp Med (1967) 3.70
The uptake, storage, and intracellular hydrolysis of carbohydrates by macrophages. J Exp Med (1969) 3.66
Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide. J Exp Med (1979) 3.61
The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin. J Exp Med (1987) 3.61
A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J Exp Med (1989) 3.58
Rapid accurate field diagnosis of Indian visceral leishmaniasis. Lancet (1998) 3.55
Macrophage deactivating factor and transforming growth factors-beta 1 -beta 2 and -beta 3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-gamma. J Immunol (1990) 3.55
Effects of concanavalin A on mouse peritoneal macrophages. I. Stimulation of endocytic activity and inhibition of phago-lysosome formation. J Exp Med (1974) 3.52
The cutaneous infiltrates of leprosy: cellular characteristics and the predominant T-cell phenotypes. N Engl J Med (1982) 3.52
Gamma-interferon is the factor in lymphokine that activates human macrophages to inhibit intracellular Chlamydia psittaci replication. J Immunol (1983) 3.49
Macrophage oxygen-dependent antimicrobial activity. III. Enhanced oxidative metabolism as an expression of macrophage activation. J Exp Med (1980) 3.43
Gram-negative endotoxin: an extraordinary lipid with profound effects on eukaryotic signal transduction. FASEB J (1991) 3.41
The in vitro differentiation of mononuclear phagocytes. IV. The ultrastructure of macrophage differentiation in the peritoneal cavity and in culture. J Exp Med (1966) 3.41
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules. Proc Natl Acad Sci U S A (1985) 3.31
Reduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophages. J Biol Chem (1989) 3.31
In vitro induction of lysosomal enzymes by phagocytosis. J Exp Med (1970) 3.11
Plasma membrane synthesis in the macrophage following phagocytosis of polystyrene latex particles. J Biol Chem (1972) 3.10
Killing of intracellular Leishmania donovani by human mononuclear phagocytes. Evidence for oxygen-dependent and -independent leishmanicidal activity. J Clin Invest (1983) 3.06
The protean manifestations of Mycoplasma pneumoniae infection in adults. Am J Med (1975) 3.06
Identification of a novel cell type in peripheral lymphoid organs of mice. IV. Identification and distribution in mouse spleen. J Exp Med (1975) 3.03
Activation of human macrophages. Comparison of other cytokines with interferon-gamma. J Exp Med (1984) 3.02
Regulation of arachidonic acid metabolites in macrophages. J Exp Med (1980) 3.00
Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide. J Exp Med (1989) 2.99
Suppression of arthritis by an inhibitor of nitric oxide synthase. J Exp Med (1993) 2.98
The pinocytic rate of activated macrophages. J Exp Med (1975) 2.97
Macrophage oxygen-dependent antimicrobial activity. I. Susceptibility of Toxoplasma gondii to oxygen intermediates. J Exp Med (1979) 2.93
Selective iodination and polypeptide composition of pinocytic vesicles. J Cell Biol (1980) 2.91
Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages. J Cell Biol (1980) 2.83
Mouse spleen lymphoblasts generated in vitro. Recovery in high yield and purity after floatation in dense bovine plasma albumin solutions. J Exp Med (1978) 2.75
A simple method for counting adherent cells: application to cultured human monocytes, macrophages and multinucleated giant cells. J Immunol Methods (1983) 2.75
The membrane proteins of the vacuolar system. II. Bidirectional flow between secondary lysosomes and plasma membrane. J Cell Biol (1980) 2.69
Serious infections from Bacillus sp. JAMA (1979) 2.67
Antibiotic proteins of human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A (1989) 2.59
Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs. FASEB J (1991) 2.57
Streptococcus bovis bacteremia and underlying gastrointestinal disease. Arch Intern Med (1978) 2.54
Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus. Proc Natl Acad Sci U S A (1980) 2.53
The macrophage. Int Rev Cytol (1973) 2.52
Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani. J Exp Med (1999) 2.51
The selective inhibition of macrophage phagocytic receptors by anti-membrane antibodies. J Exp Med (1972) 2.51