Published in J Biol Chem on October 10, 1970
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci U S A (1974) 8.30
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
Pathways of prostaglandin F2alpha metabolism in mammalian kidneys. Br J Pharmacol (1977) 1.40
Prostaglandins and the gastrointestinal tract. Gut (1973) 1.20
Carboxyethyllysine in a protein: native carbonyl reductase/NADP(+)-dependent prostaglandin dehydrogenase. Proc Natl Acad Sci U S A (1993) 1.11
Changes in bone and bone marrow of rabbits bearing the VX-2 carcinoma. A comparison of local and distant effects. Am J Pathol (1977) 0.91
Identification of 13,14-dihydro-15-oxo-prostaglandin F2 alpha in the circulation during infusions of bradykinin and prostaglandin E2 in man. Br J Pharmacol (1987) 0.88
The prostanoids in hemostasis and thrombosis: a review. Am J Pathol (1980) 0.83
Bradykinin-stimulated prostaglandin synthesis in conscious rabbits. Br J Pharmacol (1987) 0.82
Blood plasma influences anti-aggregatory potency of prostaglandins: effect of albumin. Inflammopharmacology (1999) 0.76
Proceedings: The reduction of prostaglandin E2 to prostaglandin F2alpha by various animal tissues. Br J Pharmacol (1974) 0.75
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 10.82
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci U S A (1974) 8.30
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1973) 4.43
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A (1974) 4.10
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases. J Biol Chem (1976) 3.82
Prostaglandins and thromboxanes. Annu Rev Biochem (1978) 3.47
On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase. J Biol Chem (1967) 3.30
Oxygenation of unsaturated fatty acids by the vesicular gland of sheep. J Biol Chem (1967) 2.93
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature (1976) 2.83
Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis. Proc Natl Acad Sci U S A (1975) 2.75
Prostaglandin endoperoxides. VII. Novel transformations of arachidonic acid in guinea pig lung. Biochem Biophys Res Commun (1974) 2.56
Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc Natl Acad Sci U S A (1984) 2.46
On the formation of thromboxane B2 and 12l-hydroxy-5,8,10,14-eicosatetraenoic acid (12 ho-20:4) in tissues from the guinea pig. Biochim Biophys Acta (1976) 2.12
Prostaglandins. Annu Rev Biochem (1975) 2.09
Steric analysis of hydroperoxides formed by lipoxygenase oxygenation of linoleic acid. Anal Biochem (1971) 2.09
On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha. J Biol Chem (1967) 2.02
Prostaglandins in human seminal plasma. Prostaglandins and related factors 46. J Biol Chem (1966) 1.91
Prostaglandin endoperoxides IV. Effects on smooth muscle. Life Sci (1975) 1.89
Thromboxane A2: effects on airway and vascular smooth muscle. Prostaglandins (1977) 1.82
Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency. Proc Natl Acad Sci U S A (1975) 1.74
Molecular cloning of allene oxide cyclase. The enzyme establishing the stereochemistry of octadecanoids and jasmonates. J Biol Chem (2000) 1.72
On the metabolism of prostaglandins E 1 and E 2 in man. J Biol Chem (1971) 1.71
Prostaglandin d2 as a potential antithrombotic agent. Prostaglandins (1975) 1.47
Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem (1995) 1.45
Inhibition of prostaglandin synthesis in man. Biochem Biophys Res Commun (1972) 1.43
Preparation, isolation, and characterization of a derivative of malonaldehyde. Anal Biochem (1968) 1.42
Identification of prostaglandin D2 as a major prostaglandin in homogenates of rat brain. Prostaglandins (1977) 1.26
Isomerization of prostaglandin H2 into prostaglandin D2 in the presence of serum albumin. Biochim Biophys Acta (1976) 1.25
Involvement of endoperoxides and thromboxanes in anaphylactic reactions. Adv Prostaglandin Thromboxane Res (1976) 1.24
On the formation and effects of thromboxane A2 in human platelets. Acta Physiol Scand (1976) 1.22
Metabolism of 8,11,14-eicosatrienoic acid in human platelets. Biochim Biophys Acta (1976) 1.22
Prostaglandin endoperoxides IX. Characterization of rabbit aorta contracting substance (RCS) from guinea pig lung and human platelets. Acta Physiol Scand (1975) 1.21
Trihydroxytetraenes: a novel series of compounds formed from arachidonic acid in human leukocytes. Biochem Biophys Res Commun (1984) 1.19
Extraction and chromatographic procedures for purification of prostaglandins, thromboxanes, prostacyclin, and their metabolites. Adv Prostaglandin Thromboxane Res (1978) 1.19
On the mechanism of the oxygenation of arachidonic acid by human platelet lipoxygenase. Biochem Biophys Res Commun (1980) 1.18
Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall. Biochim Biophys Acta (1985) 1.18
Identification of 15-hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE) as a major metabolite of arachidonic acid in human lung. Acta Physiol Scand (1980) 1.16
Decomposition of unsaturated fatty acid hydroperoxides by hemoglobin: Structures of major products of 13L-hydroperoxy-9,11-octadecadienoic acid. Lipids (1975) 1.13
The structure of a urinary metabolite of prostaglandin E2 in the guinea pig. Biochem Biophys Res Commun (1969) 1.12
The role of prostaglandin endoperoxides and thromboxanes in platelet aggregation. Adv Prostaglandin Thromboxane Res (1976) 1.12
Oxylipin profiling reveals the preferential stimulation of the 9-lipoxygenase pathway in elicitor-treated potato cells. J Biol Chem (2000) 1.10
Glucocorticoid in inflammatory proliferative skin disease reduces arachidonic and hydroxyeicosatetraenoic acids. Science (1977) 1.05
Spontaneous effect of increased stability of the lower lumbar spine in cases of severe chronic back pain. The answer of an external transpeduncular fixation test. Clin Orthop Relat Res (1986) 1.05
A linoleic acid (8R)-dioxygenase and hydroperoxide isomerase of the fungus Gaeumannomyces graminis. Biosynthesis of (8R)-hydroxylinoleic acid and (7S,8S)-dihydroxylinoleic acid from (8R)-hydroperoxylinoleic acid. J Biol Chem (1992) 1.04
Formation and action of prostaglandin endoperoxides in the isolated human umbilical artery. Acta Physiol Scand (1976) 1.04
Divinyl ether synthase from garlic (Allium sativum L.) bulbs: sub-cellular localization and substrate regio-and stereospecificity. FEBS Lett (1996) 1.04
Novel transformations of prostaglandin endoperoxides: formation of thromboxanes. Adv Prostaglandin Thromboxane Res (1976) 1.03
A comparison of the vasodepressor effects of the cyclic effects of the cyclic endoperoxides PGG, and PGH2 with those of PGD2 and PGE2 in hypertensive and normotensive rats. Eur J Pharmacol (1976) 1.00
Prostaglandins in human burn blister fluid. Acta Physiol Scand (1973) 1.00
Absolute configuration of the prostaglandins. Nature (1966) 1.00
Metabolism of prostaglandin E2 in guinea pig liver. II. Pathways in the formation of the major metabolites. J Biol Chem (1971) 0.99
On the mechanism of biosynthesis of leukotrienes and related compounds. FEBS Lett (1982) 0.98
Metabolism of prostaglandins in rat liver mitochondria. Eur J Biochem (1968) 0.97
Thromboxane a2: biosynthesis and effects on platelets. Adv Prostaglandin Thromboxane Leukot Res (1982) 0.97
Quantitative gas chromatography of prostaglandin E1 at the Nanogram level: use of deuterated carrier and multiple-ion analyzer. Anal Biochem (1970) 0.96
Stimulation of renin release from rabbit renal cortex by arachidonic acid and prostaglandin endoperoxides. Circ Res (1976) 0.96
Letter: Mechanism of the anti-aggregating effect of aspirin on human platelets. Lancet (1974) 0.96
Maintenance of the tone of the human umbilical artery by prostaglandin and thromboxane formation. Adv Prostaglandin Thromboxane Res (1976) 0.95
A novel transformation of 13-LS-hydroperoxy-9,11-octadecadienoic acid. Biochim Biophys Acta (1983) 0.94
Chemical instability of 15-keto-13,14-dihydro-PGE2: the reason for low assay reliability. Prostaglandins (1980) 0.94
The structure of the major urinary metabolite of prostaglandin E2 in man. J Am Chem Soc (1969) 0.94
Metabolism of prostaglandin E 2 in guinea pig liver. Ann N Y Acad Sci (1971) 0.94
Bis-allylic hydroxylation of polyunsaturated fatty acids by hepatic monooxygenases and its relation to the enzymatic and nonenzymatic formation of conjugated hydroxy fatty acids. Arch Biochem Biophys (1993) 0.93
On the stereochemistry and biosynthesis of lipoxin B. Proc Natl Acad Sci U S A (1986) 0.92
Prostaglandin biosynthesis in the human umbilical cord. Biol Neonate (1976) 0.92
On the specificity of allene oxide cyclase. Lipids (1999) 0.92
Stabilization of purified human 5-lipoxygenase with glutathione peroxidase and superoxide dismutase. Anal Biochem (1994) 0.92
On the metabolism of prostaglandins E 1 and E 2 in the guinea pig. J Biol Chem (1972) 0.91
Oxygenation of (3Z)-nonenal to (2E)-4-hydroxy-2-nonenal in the broad bean (Vicia faba L.). J Biol Chem (1993) 0.91
Novel biological transformations of 15-Ls-hydroperoxy-5,8,11,13-eicosatetraenoic acid. Biochim Biophys Acta (1986) 0.91
Icreased excretion of 5alpha, 7alpha-dihydroxy-11-keto-tetranor-prostanoic acid on anaphylaxis in the guinea-pig. Prostaglandins (1974) 0.90
15-Lipoxygenase in human platelets. J Biol Chem (1985) 0.90
Biosynthesis of conjugated triene-containing fatty acids by a novel isomerase from the red marine alga Ptilota filicina. Biochemistry (1994) 0.90
Measurement of prostaglandins, thromboxanes, prostacyclin and their metabolites by gas liquid chromatography--mass spectrometry. Adv Prostaglandin Thromboxane Res (1978) 0.89
Inhibition of basal and hormone-stimulated adenylate cyclase in adipocyte ghosts by the prostaglandin endoperoxide prostaglandin H2. J Biol Chem (1975) 0.89
The lipoxygenase activity of myoglobin. Oxidation of linoleic acid by the ferryl oxygen rather than protein radical. J Biol Chem (1994) 0.89
A gas-liquid chromatographic method for steric analysis of epoxy acids. Chem Phys Lipids (1989) 0.89
Omega-hydroxylation of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid in human polymorphonuclear leukocytes. J Biol Chem (1984) 0.87
Oxylipin metabolism in the red alga Gracilariopsis lemaneiformis: mechanism of formation of vicinal dihydroxy fatty acids. Arch Biochem Biophys (1991) 0.87
15(S)-hydroxyeicosatetraenoic acid is the major arachidonic acid metabolite in human bronchi: association with airway epithelium. Arch Biochem Biophys (1990) 0.87
Increased synthesis of prostaglandins in the guinea pig following scalding injury. Acta Physiol Scand (1973) 0.87
Formation of cyclopentenones from all-(E) hydroperoxides of linoleic acid via allene oxides. New insight into the mechanism of cyclization. FEBS Lett (2000) 0.86
Quantitative studies on prostaglandin synthesis in man. 3. Excretion of the major urinary metabolite of prostaglandins F 1 alpha and F 2 alpha during pregnancy. Life Sci (1974) 0.86
Biosynthesis of prostaglandin F2alpha from arachidonic acid and prostaglandin endoperoxides in the uterus. Biochim Biophys Acta (1976) 0.86
Thromboxane A2 and prostaglandin H2: potent stimulators of the swine coronary artery. Prostaglandins (1976) 0.86
Transformations of 5,8,11,14,17-eicosapentaenoic acid in human platelets. Biochim Biophys Acta (1980) 0.86
On the mechanism of biosynthesis of divinyl ether oxylipins by enzyme from garlic bulbs. Eur J Biochem (1997) 0.86
Circulating hydroxy fatty acids in familial Mediterranean fever. Proc Natl Acad Sci U S A (1985) 0.85
Biosynthesis of prostaglandin E1 by human seminal vesicles. Lipids (1976) 0.85
Stereochemistry in the formation of 9-hydroxy-10,12-octadecadienoic acid and 13-hydroxy-9,11-octadecadienoic acid from linoleic acid by fatty acid cyclooxygenase. Biochim Biophys Acta (1980) 0.84
-Oxidation of fatty acids. II. Enzymatic oxido-reduction of 17-hydroxystearic acid. J Biol Chem (1971) 0.83
Arachidonic acid metabolism in the human mast cell line HMC-1: 5-lipoxygenase gene expression and biosynthesis of thromboxane. Biochim Biophys Acta (1995) 0.83
The effect of eight new prostaglandins on human myometrium. Acta Physiol Scand (1967) 0.83
The lipoxygenase pathway in tulip (Tulipa gesneriana): detection of the ketol route. Biochem J (2000) 0.83
-Oxidation of fatty acids. I. Mechanism of microsomal 1- and 2-hydroxylation. J Biol Chem (1971) 0.82
On the specificity of the lipoxidase catalyzed oxygenation of unsaturated fatty acids. Biochem Biophys Res Commun (1965) 0.82
Metabolism and effect of prostaglandin H2 in adipose tissue. Prostaglandins (1976) 0.82
Properties of the soluble arachidonic acid 15-lipoxygenase and 15-hydroperoxide isomerase from the oomycete Saprolegnia parasitica. Prostaglandins (1987) 0.81