Published in Annu Rev Biochem on January 01, 1975
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Estimated rate of thromboxane secretion into the circulation of normal humans. J Clin Invest (1986) 1.15
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A role for endogenous mono-hydroxy-eicosatetraenoic acids (HETEs) in the regulation of human neutrophil migration. Immunology (1980) 1.10
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Release of arachidonic acid from human lymphocytes in response to mitogenic lectins. J Exp Med (1979) 0.98
Calcium-dependent action of osmolality on adenosine 3',5'-monophosphate accumulation in rat renal inner medulla: evidence for a relationship to calcium-responsive arachidonate release and prostaglandin synthesis. J Clin Invest (1980) 0.94
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Structural requirements for the activity of an immunologically generated lipid chemotactic factor. Immunology (1980) 0.93
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Effects of prostaglandins E2 and I2 on human lymphocyte transformation in the presence and absence of inhibitors of prostaglandin biosynthesis. Br J Pharmacol (1979) 0.86
The effect of omega-3 fatty acids on bronchial hyperresponsiveness, sputum eosinophilia, and mast cell mediators in asthma. Chest (2015) 0.84
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Purification, cDNA cloning and expression of 15-oxoprostaglandin 13-reductase from pig lung. Biochem J (1998) 0.81
Acute phase reactants ceruloplasmin and haptoglobin and their relationship to plasma prostaglandins in rabbits bearing the VS2 carcinoma. J Exp Med (1978) 0.80
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Phosphatidylinositol-specific phospholipase C in fetal membranes and uterine decidua. J Clin Invest (1981) 0.79
The arachidonic acid cascade. The prostaglandins, thromboxanes and leukotrienes. Inflammation (1984) 0.79
Regulation of mammary and adipose tissue lipoprotein lipase and blood triacylglycerol in rats during late pregnancy. Effect of prostaglandins. J Clin Invest (1977) 0.79
The effects of cyclooxygenase and nitric oxide synthase inhibition on cardiodynamic parameters and coronary flow in isolated rat hearts. Exp Clin Cardiol (2013) 0.76
PAMAM dendrimers as nano carriers to investigate inflammatory responses induced by pulmonary exposure of PCB metabolites in Sprague-Dawley rats. Environ Sci Pollut Res Int (2015) 0.75
Effect of histamine, acetylcholine and compound 48/80 on bronchoconstriction and release of eicosanoids in the dog. Agents Actions (1984) 0.75
Biomarkers for the Phenotyping and Monitoring of Asthma in Children. Curr Treat Options Allergy (2016) 0.75
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 10.82
Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science (1983) 9.51
Invasive group A streptococcal infections in Ontario, Canada. Ontario Group A Streptococcal Study Group. N Engl J Med (1996) 8.41
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science (1987) 8.36
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci U S A (1974) 8.30
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187. Proc Natl Acad Sci U S A (1979) 6.34
Leukotriene C: a slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci U S A (1979) 5.33
Submarine thermal sprirngs on the galapagos rift. Science (1979) 5.18
Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1973) 4.43
Titration of antibodies to salmonella O antigens by enzyme-linked immunosorbent assay. Infect Immun (1972) 4.13
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A (1974) 4.10
Leukotrienes are potent constrictors of human bronchi. Nature (1980) 4.04
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases. J Biol Chem (1976) 3.82
Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci U S A (1999) 3.61
Prostaglandins and thromboxanes. Annu Rev Biochem (1978) 3.47
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U S A (1981) 3.42
Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem (1968) 3.41
On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase. J Biol Chem (1967) 3.30
Sequence of the fourth gene of human rotaviruses recovered from asymptomatic or symptomatic infections. J Virol (1988) 3.20
Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid. J Biol Chem (1979) 3.16
Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. Proc Natl Acad Sci U S A (1979) 3.14
Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds. J Biol Chem (1979) 3.08
Utility of the housekeeping genes 18S rRNA, beta-actin and glyceraldehyde-3-phosphate-dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytes. Scand J Immunol (2004) 3.03
The evolution of methicillin-resistant Staphylococcus aureus in Canadian hospitals: 5 years of national surveillance. CMAJ (2001) 2.99
Oxygenation of unsaturated fatty acids by the vesicular gland of sheep. J Biol Chem (1967) 2.93
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature (1976) 2.83
Leukotriene D: a slow reacting substance from rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1980) 2.77
Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis. Proc Natl Acad Sci U S A (1975) 2.75
Antigen from colon of germfree rats and antibodies in human ulcerative colitis. Ann N Y Acad Sci (1965) 2.72
Prostaglandin endoperoxides. VII. Novel transformations of arachidonic acid in guinea pig lung. Biochem Biophys Res Commun (1974) 2.56
Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc Natl Acad Sci U S A (1984) 2.46
Conservation of the fourth gene among rotaviruses recovered from asymptomatic newborn infants and its possible role in attenuation. J Virol (1986) 2.42
Structure of leukotriene C. Identification of the amino acid part. Biochem Biophys Res Commun (1979) 2.30
Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res (1999) 2.25
Biosynthesis of prostaglandins. Fed Proc (1972) 2.23
Biosynthesis of prostaglandins from arachidonic acid in guinea pig lung. Prostaglandins and related factors. 38. J Biol Chem (1965) 2.23
Haemolytic activity of human blood monocytes. Lysis of human erythrocytes treated with anti-A serum. Clin Exp Immunol (1973) 2.21
On the formation of thromboxane B2 and 12l-hydroxy-5,8,10,14-eicosatetraenoic acid (12 ho-20:4) in tissues from the guinea pig. Biochim Biophys Acta (1976) 2.12
Immunological studies in ulcerative colitis. 3. Incidence of antibodies to colon-antigen in ulcerative colitis and other gastro-intestinal diseases. Clin Exp Immunol (1966) 2.11
Steric analysis of hydroperoxides formed by lipoxygenase oxygenation of linoleic acid. Anal Biochem (1971) 2.09
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proc Natl Acad Sci U S A (1984) 2.05
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence. Blood (1981) 2.05
Identification and biological activity of novel omega-oxidized metabolites of leukotriene B4 from human leukocytes. FEBS Lett (1981) 2.04
On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha. J Biol Chem (1967) 2.02
Immunological studies in ulcerative colitis. IV. Origin of autoantibodies. J Exp Med (1968) 2.02
Allergen challenge of lung tissue from asthmatics elicits bronchial contraction that correlates with the release of leukotrienes C4, D4, and E4. Proc Natl Acad Sci U S A (1983) 2.01
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc Natl Acad Sci U S A (1986) 1.97
The chemical composition of the cytoplasmic membrane of Bacillus subtilis. Eur J Biochem (1967) 1.96
Improved experimental limit on the electric dipole moment of the neutron. Phys Rev Lett (2006) 1.96
Metabolism of prostaglandin E2 in guinea pig liver. I. Identification of seven metabolites. J Biol Chem (1970) 1.92
Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. Ontario Group A Streptococcal Study Group. Pediatrics (2000) 1.91
On the nature of the 5-lipoxygenase reaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors. Proc Natl Acad Sci U S A (1985) 1.91
Prostaglandins in human seminal plasma. Prostaglandins and related factors 46. J Biol Chem (1966) 1.91
CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range. J Mol Biol (1995) 1.90
Phospholipid precursors of prostaglandins. Biochim Biophys Acta (1968) 1.90
Prostaglandin endoperoxides IV. Effects on smooth muscle. Life Sci (1975) 1.89
Autoantibodies to colon in rats and human ulcerative colitis: cross reactivity with Escherichia coli O:14 antigen. Proc Soc Exp Biol Med (1967) 1.86
Relationship between homocysteine and superoxide dismutase in homocystinuria: possible relevance to cardiovascular risk. Arterioscler Thromb Vasc Biol (2000) 1.86
Thromboxane A2: effects on airway and vascular smooth muscle. Prostaglandins (1977) 1.82
Gap junction protein phenotypes of the human heart and conduction system. J Cardiovasc Electrophysiol (1995) 1.79
Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency. Proc Natl Acad Sci U S A (1975) 1.74
Molecular cloning of allene oxide cyclase. The enzyme establishing the stereochemistry of octadecanoids and jasmonates. J Biol Chem (2000) 1.72
On the metabolism of prostaglandins E 1 and E 2 in man. J Biol Chem (1971) 1.71
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem (1984) 1.70
Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis. Clin Exp Immunol (2003) 1.70
Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. Biochem Biophys Res Commun (1982) 1.69
Quantitation of Salmonella O-antibodies in human sera by enzyme-linked immunosorbent assay (ELISA). Int Arch Allergy Appl Immunol (1975) 1.66
Synthesis and biological properties of a 9,11-azo-prostanoid: highly active biochemical mimic of prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 1.64
Inhibition of leukotriene C and leukotriene D biosynthesis. J Biol Chem (1980) 1.64
Sudden death in individuals in hobble restraints during paramedic transport. Ann Emerg Med (1995) 1.62