Published in J Gen Physiol on February 01, 1971
Permeability of muscle capillaries to small heme-peptides. Evidence for the existence of patent transendothelial channels. J Cell Biol (1975) 3.42
Osmotic extraction of hypotonic fluid from the lungs. J Clin Invest (1974) 1.02
Paracellular permeability of extracellular space markers across rat jejunum in vitro. Indication of a transepithelial fluid circuit. J Physiol (1977) 1.02
Solute flux coupling in a homopore membrane. J Gen Physiol (1974) 1.01
Role of solute drag in intestinal transport. J Gen Physiol (1985) 0.91
Convective paracellular solute flux. A source of ion-ion interaction in the epithelial transport equations. J Gen Physiol (1987) 0.87
Lysine transport across rat jejunum: distribution between the transcellular and the paracellular routes. J Physiol (1979) 0.86
Transport across homoporous and heteroporous membranes in nonideal, nondilute solutions. II. Inequality of phenomenological and tracer solute permeabilities. Biophys J (1981) 0.75
Thermodynamic analysis of the permeability of biological membranes to non-electrolytes. Biochim Biophys Acta (1958) 12.97
A physical interpretation of the phenomenological coefficients of membrane permeability. J Gen Physiol (1961) 7.23
Anomalous transport of electrolytes and sucrose through the isolated frog skin induced by hypertonicity of the outside bathing solution. Ann N Y Acad Sci (1966) 2.24
Hyperosmolarity and the net transport of nonelectrolytes in frog skin. J Gen Physiol (1967) 1.54
Thermodynamics of flow processes in biological systems. Biophys J (1962) 1.53
Tracer diffusion and unidirectional fluxes. Biophys J (2008) 1.39
Further observations on asymmetrical solute movement across membranes. J Gen Physiol (1968) 1.15
The interpretation of tracer fluxes in terms of membrane structure. Q Rev Biophys (1969) 1.11
Anomalous transport of sucrose and urea in toad skin. Nephron (1969) 1.07
The coupling of solute fluxes in membranes. J Gen Physiol (1970) 0.96
Coupled solute fluxes in toad skin. J Gen Physiol (1968) 0.93
Convection, diffusion, and electric current through a membrane. Acta Physiol Scand (1966) 0.83
The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem (1977) 11.55
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab (1983) 9.59
Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Generalizations. J Cereb Blood Flow Metab (1985) 5.99
Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome. JAMA (2001) 5.13
The flow of solute and solvent across a two-membrane system. J Theor Biol (1963) 4.70
Some relations between changes in the linear electrical properties of striated muscle fibers and changes in ultrastructure. J Gen Physiol (1967) 4.53
The effect of white matter hyperintensity volume on brain structure, cognitive performance, and cerebral metabolism of glucose in 51 healthy adults. Neurology (1995) 3.95
Method for quantification of brain, ventricular, and subarachnoid CSF volumes from MR images. J Comput Assist Tomogr (1992) 3.62
Dissociation of object and spatial visual processing pathways in human extrastriate cortex. Proc Natl Acad Sci U S A (1991) 3.15
Increasing annual incidence of primary malignant brain tumors in the elderly. J Natl Cancer Inst (1990) 2.34
Face encoding and recognition in the human brain. Proc Natl Acad Sci U S A (1996) 2.31
Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease. Neurology (1998) 2.24
Network analysis of cortical visual pathways mapped with PET. J Neurosci (1994) 2.14
Kinetics of neutral amino acid transport across the blood-brain barrier. J Neurochem (1987) 2.09
Altered brain functional connectivity and impaired short-term memory in Alzheimer's disease. Brain (2001) 2.05
Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism. J Neurochem (1991) 2.01
Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem (1996) 1.96
X-chromosome effects on female brain: a magnetic resonance imaging study of Turner's syndrome. Lancet (1993) 1.93
Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch Gen Psychiatry (1996) 1.90
An in situ brain perfusion technique to study cerebrovascular transport in the rat. Am J Physiol (1984) 1.87
The cerebral metabolic landscape in autism. Intercorrelations of regional glucose utilization. Arch Neurol (1988) 1.86
Critical analysis of the use of computer-assisted transverse axial tomography to study human brain in aging and dementia of the Alzheimer type. Neurology (1990) 1.84
Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes. J Cereb Blood Flow Metab (1983) 1.80
Osmotic opening of tight junctions in cerebral endothelium. J Comp Neurol (1973) 1.75
Age-related differences in volumes of subcortical nuclei, brain matter, and cerebrospinal fluid in healthy men as measured with magnetic resonance imaging. Arch Neurol (1992) 1.70
Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Revisualization during pharmacotherapy. Arch Gen Psychiatry (1992) 1.69
Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. Mol Psychiatry (2009) 1.64
Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. Neuropharmacology (1998) 1.63
Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type. Arch Neurol (1990) 1.62
Efflux of radiolabeled polyethylene glycols and albumin from rat brain. Am J Physiol (1981) 1.62
Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex. Mol Psychiatry (2006) 1.60
Drainage of interstitial fluid from different regions of rat brain. Am J Physiol (1984) 1.58
Measurements of dog blood-brain transfer constants by ventriculocisternal perfusion. Am J Physiol (1975) 1.56
Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Arch Gen Psychiatry (1989) 1.56
Premutation female carriers of fragile X syndrome: a pilot study on brain anatomy and metabolism. J Am Acad Child Adolesc Psychiatry (1999) 1.55
Striatal 18F-dopa uptake: absence of an aging effect. J Cereb Blood Flow Metab (1993) 1.52
Positron emission tomography in Alzheimer's disease. Neurology (1986) 1.52
A quantitative method for measuring regional in vivo fatty-acid incorporation into and turnover within brain phospholipids: review and critical analysis. Brain Res Brain Res Rev (1993) 1.51
Intercorrelations of glucose metabolic rates between brain regions: application to healthy males in a state of reduced sensory input. J Cereb Blood Flow Metab (1984) 1.51
Local cerebral glucose utilization in controlled graded levels of hyperglycemia in the conscious rat. J Cereb Blood Flow Metab (1988) 1.49
Mechanical properties of the sarcolemma and myoplasm in frog muscle as a function of sarcomere length. J Gen Physiol (1972) 1.48
Volumes of medial temporal lobe structures in patients with Alzheimer's disease and mild cognitive impairment (and in healthy controls). Biol Psychiatry (1998) 1.44
Effects of postnatal dexamethasone on blood-brain barrier permeability and brain water content in newborn lambs. Am J Physiol Regul Integr Comp Physiol (2001) 1.44
Neuroimaging and affective disorder in late life: a review. Can J Psychiatry (1990) 1.44
Quantitative CT analysis of brain morphometry in adult Down's syndrome at different ages. Neurology (1987) 1.43
Characteristics of p-aminohippurate transport in proximal renal tubules. Am J Physiol (1969) 1.43
n-3 polyunsaturated fatty acid deprivation in rats decreases frontal cortex BDNF via a p38 MAPK-dependent mechanism. Mol Psychiatry (2006) 1.43
Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am J Physiol (1978) 1.43
Vascular dementia: stroke prevention takes on new urgency. Geriatrics (1993) 1.42
Model for drug uptake by brain tumors: effects of osmotic treatment and of diffusion in brain. J Cereb Blood Flow Metab (1990) 1.42
Age-related changes in regional cerebral blood flow during working memory for faces. Neuroimage (1998) 1.42
Brain atrophy in hypertension. A volumetric magnetic resonance imaging study. Hypertension (1992) 1.42
Longitudinal changes in lateral ventricular volume in patients with dementia of the Alzheimer type. Neurology (1992) 1.39
Metabolic correlates of fatigue and of recovery from fatigue in single frog muscle fibers. J Gen Physiol (1978) 1.37
Loss of proteins regulating synaptic plasticity in normal aging of the human brain and in Alzheimer disease. J Neuropathol Exp Neurol (1999) 1.37
Brain metabolite concentration and dementia severity in Alzheimer's disease: a (1)H MRS study. Neurology (2001) 1.35
Quantitative aspects of reversible osmotic opening of the blood-brain barrier. Am J Physiol (1980) 1.33
Sucrose and inulin space measurements of cerebral cortex in four mammalian species. Am J Physiol (1970) 1.32
Swelling of the transverse tubular system in frog sartorius. J Gen Physiol (1969) 1.31
Epigenetic modifications in frontal cortex from Alzheimer's disease and bipolar disorder patients. Transl Psychiatry (2012) 1.31
Cerebrospinal fluid production is reduced in healthy aging. Neurology (1990) 1.31
Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. Neuropharmacology (1999) 1.29
Relations between neuropsychological and cerebral metabolic asymmetries in early Alzheimer's disease. J Cereb Blood Flow Metab (1985) 1.26
Modification of the blood-brain barrier in the chemotherapy of malignant brain tumors. Fed Proc (1984) 1.25
Testing of a hypothesis for osmotic opening of the blood-brain barrier. Am J Physiol (1972) 1.25
Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Arch Neurol (1998) 1.25
Albumin outflow into deep cervical lymph from different regions of rabbit brain. Am J Physiol (1991) 1.23
Visual cortical dysfunction in Alzheimer's disease evaluated with a temporally graded "stress test" during PET. Am J Psychiatry (1996) 1.23
A fixed charge model of the transverse tubular system of frog sartorius. J Gen Physiol (1969) 1.22
Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? Mol Psychiatry (2008) 1.21
A two-dimensional, finite element analysis of vasogenic brain edema. Neurol Med Chir (Tokyo) (1990) 1.21
Longitudinal study of the early neuropsychological and cerebral metabolic changes in dementia of the Alzheimer type. J Clin Exp Neuropsychol (1988) 1.20
Impairment in mitochondrial cytochrome oxidase gene expression in Alzheimer disease. Brain Res Mol Brain Res (1994) 1.18
Effect of task difficulty on cerebral blood flow during perceptual matching of faces. Hum Brain Mapp (1996) 1.18
Heterogeneous anterior-posterior metabolic patterns in dementia of the Alzheimer type. Neurology (1988) 1.18
Isolation and quantitation of long-chain acyl-coenzyme A esters in brain tissue by solid-phase extraction. Anal Biochem (1994) 1.17
A method to obtain infusion schedules for prescribed blood concentration time courses. J Appl Physiol (1976) 1.15
Intercorrelations of regional cerebral glucose metabolic rates in Alzheimer's disease. Brain Res (1987) 1.15
Altered arachidonic acid cascade enzymes in postmortem brain from bipolar disorder patients. Mol Psychiatry (2009) 1.14
Disease and anatomic specificity of ethanolamine plasmalogen deficiency in Alzheimer's disease brain. Brain Res (1995) 1.14
The aging human brain. Ann Neurol (1985) 1.13
A component of fluid absorption linked to passive ion flows in the superficial pars recta. J Gen Physiol (1975) 1.13
Ontogeny of blood-brain barrier function in ovine fetuses, lambs, and adults. Am J Physiol (1996) 1.11
Nutritional deprivation of alpha-linolenic acid decreases but does not abolish turnover and availability of unacylated docosahexaenoic acid and docosahexaenoyl-CoA in rat brain. J Neurochem (2000) 1.11
The significance of age-related enlargement of the cerebral ventricles in healthy men and women measured by quantitative computed X-ray tomography. J Am Geriatr Soc (1992) 1.11
Osmotic opening of the blood-brain barrier in the monkey without associated neurological deficits. Science (1973) 1.11
Reversible osmotic opening of the blood-brain barrier. Science (1971) 1.11
Arecoline-stimulated brain incorporation of intravenously administered fatty acids in unanesthetized rats. J Neurochem (1991) 1.11
Relation between free fatty acid and acyl-CoA concentrations in rat brain following decapitation. Neurochem Res (1997) 1.10
Extracellular volume decreases while cell volume is maintained by ion uptake in rat brain during acute hypernatremia. J Physiol (1991) 1.10
Regulation of the microenvironment of peripheral nerve: role of the blood-nerve barrier. Prog Neurobiol (1987) 1.10
Neocortical metabolic abnormalities precede nonmemory cognitive defects in early Alzheimer's-type dementia. Arch Neurol (1986) 1.09
Activation of cerebral blood flow during a visuoperceptual task in patients with Alzheimer-type dementia. Neurobiol Aging (1993) 1.09
Phospholipid composition and levels are altered in Down syndrome brain. Brain Res (2000) 1.08
Saturable transport of manganese(II) across the rat blood-brain barrier. J Neurochem (1991) 1.08
Volumetric magnetic resonance imaging in men with dementia of the Alzheimer type: correlations with disease severity. Biol Psychiatry (1993) 1.08
Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer's disease brain. Transl Psychiatry (2011) 1.08
In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EEG and PET. J Neural Transm (Vienna) (2002) 1.07
The anisotropic elastic properties of the sarcolemma of the frog semitendinosus muscle fiber. Biophys J (1973) 1.07
Examination of blood-brain barrier permeability in dementia of the Alzheimer type with [68Ga]EDTA and positron emission tomography. J Cereb Blood Flow Metab (1987) 1.07