Published in Diabetes on August 01, 1966
Induction and acceleration of insulitis/diabetes in mice with a viral mimic (polyinosinic-polycytidylic acid) and an insulin self-peptide. Proc Natl Acad Sci U S A (2002) 1.40
Diabetes mellitus, Addison's disease and pernicious anaemia. Postgrad Med J (1968) 1.10
Cell-mediated immunity in diabetes mellitus. Proc R Soc Med (1974) 1.03
The histopathology of immune diabetes in the rabbit. Am J Pathol (1968) 0.85
Insulin-specific antibodies and insulitis in mice immunized with purified porcine insulin. Clin Exp Immunol (1982) 0.79
Insulin antibodies. Postgrad Med J (1969) 0.75
The pancreas and diabetes mellitus. Postgrad Med J (1967) 0.75
Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet (2000) 24.22
The transcriptional program in the response of human fibroblasts to serum. Science (1999) 19.19
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci U S A (1999) 14.16
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett (1995) 9.62
Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature (1996) 5.44
Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol Biol Cell (2000) 5.19
Polymersomes: tough vesicles made from diblock copolymers. Science (1999) 4.76
Epidemiology of Norwalk gastroenteritis and the role of Norwalk virus in outbreaks of acute nonbacterial gastroenteritis. Ann Intern Med (1982) 4.54
Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen. Science (1999) 4.08
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem (1998) 3.88
The frequency of a Norwalk-like pattern of illness in outbreaks of acute gastroenteritis. Am J Public Health (1982) 3.78
Interstitial cells of Cajal generate a rhythmic pacemaker current. Nat Med (1998) 3.62
Preparation of tubulin from brain. Methods Enzymol (1982) 3.39
The stabilization of proteins by sucrose. J Biol Chem (1981) 3.34
Dynamics of insulin secretion by the perfused rat pancreas. Endocrinology (1968) 3.23
Rapid penicillinase paper strip test for detection of beta-lactamase-producing Haemophilus influenzae and Neisseria gonorrhoeae. Antimicrob Agents Chemother (1977) 3.02
Vitamin D deficiency inhibits pancreatic secretion of insulin. Science (1980) 3.00
Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus. Int J Cancer (1999) 2.95
Adherence of Candida albicans and other Candida species to mucosal epithelial cells. Infect Immun (1980) 2.91
Social class and racial differences in blood pressure. Am J Public Health (1974) 2.91
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. Am J Hum Genet (1999) 2.88
The association of cancer and the nephrotic syndrome. Ann Intern Med (1966) 2.88
Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma. Cancer Res (1999) 2.87
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J Pharmacol Exp Ther (1989) 2.78
Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null mice. Hum Mol Genet (1997) 2.69
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J (1996) 2.64
Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function. J Pharmacol Exp Ther (1996) 2.63
Helicobacter pylori in dental plaque. Lancet (1993) 2.62
The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes. Microbiology (1997) 2.61
Missense mutations in the adhalin gene linked to autosomal recessive muscular dystrophy. Cell (1994) 2.60
Identification of mitogen-activated protein (MAP) kinase-activated protein kinase-3, a novel substrate of CSBP p38 MAP kinase. J Biol Chem (1996) 2.55
Insulin within islets is a physiologic glucagon release inhibitor. J Clin Invest (1984) 2.52
Hemoccult screening in detecting colorectal neoplasm: sensitivity, specificity, and predictive value. Long-term follow-up in a large group practice setting. Ann Intern Med (1990) 2.48
Reversion of the glycopeptide resistance phenotype in Staphylococcus aureus clinical isolates. Antimicrob Agents Chemother (2000) 2.48
Binding sites in Escherichia coli dihydrofolate reductase communicate by modulating the conformational ensemble. Proc Natl Acad Sci U S A (2000) 2.47
The effect of market structure on HMO premiums. J Health Econ (1995) 2.44
Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Multiple Sclerosis Collaborative Research Group. Neurology (1999) 2.40
Use of alternative techniques of hysterectomy in Ohio, 1988-1994. N Engl J Med (1996) 2.40
Cost analysis of a multiphasic screening program. N Engl J Med (1969) 2.37
Virulence of Staphylococcus aureus mutants altered in type 5 capsule production. Infect Immun (1991) 2.29
Staphylococcus aureus serotype 5 capsular polysaccharide is antiphagocytic and enhances bacterial virulence in a murine bacteremia model. Infect Immun (1998) 2.29
Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site. J Biol Chem (1997) 2.28
Constitutive production of a unique lymphokine (IL 3) by the WEHI-3 cell line. J Immunol (1982) 2.22
Smoking habits and the leukocyte count. Arch Environ Health (1973) 2.22
Cation requirements for insulin secretion in the isolated perfused pancreas. Diabetes (1966) 2.21
A threshold distribution hypothesis for packet storage of insulin and its mathematical modeling. J Clin Invest (1972) 2.20
Cytolysis induced by human lymphotoxin. Am J Pathol (1972) 2.14
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J Biol Chem (1998) 2.12
Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis. J Immunol (2000) 2.11
Characterization of Candida albicans adherence to human vaginal epithelial cells in vitro. Infect Immun (1983) 2.07
Application of fluorescence energy transfer and polarization to monitor Escherichia coli cAMP receptor protein and lac promoter interaction. Proc Natl Acad Sci U S A (1990) 2.05
Partial specific volumes and interactions with solvent components of proteins in guanidine hydrochloride. Biochemistry (1974) 2.03
The reconstitution of microtubules from purified calf brain tubulin. Biochemistry (1975) 2.02
The response of human leucocyte cultures to stimulation by tuberculin and phytohaemagglutinin measured by the uptake of radioactive thymidine. Clin Exp Immunol (1967) 2.01
In vitro reconstitution of calf brain microtubules: effects of solution variables. Biochemistry (1977) 1.99
Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun (1997) 1.99
A new nomenclature for the cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Nucleic Acids Res (1997) 1.99
The kinetics of interleukin 1 secretion from activated monocytes. Differences between interleukin 1 alpha and interleukin 1 beta. J Biol Chem (1988) 1.95
Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion. Circulation (1999) 1.93
Integration of synthetic globin genes into an E. coli plasmid. Nucleic Acids Res (1976) 1.85
A tale of four cities: Medicare reform and competitive pricing. Health Aff (Millwood) (2000) 1.83
Quantitative and temporal correlation between circulating cell-free Epstein-Barr virus DNA and tumor recurrence in nasopharyngeal carcinoma. Cancer Res (1999) 1.82
Requirement for calcium ion in insulin secretion by the perfused rat pancreas. Am J Physiol (1968) 1.82
Establishment of continuous cultures of thy1.2+, Lyt1+, 2-T cells with purified interleukin 3. Cell (1981) 1.80
The role of staphylococcal polysaccharide microcapsule expression in septicemia and septic arthritis. Infect Immun (1997) 1.80
Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase. Biochem Biophys Res Commun (1999) 1.80
SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol (2000) 1.75
Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue. J Biol Chem (1996) 1.74
Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis. Arthritis Rheum (2000) 1.72
Multiphasic checkup evaluation study. 4. Preliminary cost benefit analysis for middle-aged men. Prev Med (1973) 1.70
Development and characterization of a Staphylococcus aureus nasal colonization model in mice. Infect Immun (1999) 1.69
Employer-sponsored health insurance in 1991. Health Aff (Millwood) (1992) 1.69
The QUinapril Ischemic Event Trial (QUIET): evaluation of chronic ACE inhibitor therapy in patients with ischemic heart disease and preserved left ventricular function. Am J Cardiol (2001) 1.68
Adherence of Staphylococcus aureus to endothelial cells: influence of capsular polysaccharide, global regulator agr, and bacterial growth phase. Infect Immun (2000) 1.68
Evaluation of an ambulatory medical-care delivery system. N Engl J Med (1976) 1.68
Scale and scope economies among health maintenance organizations. J Health Econ (1996) 1.68
Phagocytic killing of encapsulated and microencapsulated Staphylococcus aureus by human polymorphonuclear leukocytes. Infect Immun (1992) 1.67
The chemical characterization of calf brain microtubule protein subunits. J Biol Chem (1973) 1.65
Staphylococcus aureus microcapsule expression attenuates bacterial virulence in a rat model of experimental endocarditis. J Infect Dis (1992) 1.64
Structural rationale for the modulation of abscess formation by Staphylococcus aureus capsular polysaccharides. Proc Natl Acad Sci U S A (2001) 1.64
Selection experiences in Medicare HMOs: pre-enrollment expenditures. Health Care Financ Rev (1999) 1.64
Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels. J Immunol (1997) 1.64
Uncovering the missing Medicaid cases and assessing their bias for estimates of the uninsured. Inquiry (2002) 1.62
Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy. J Biol Chem (2000) 1.60
Factors associated with attendance in a voluntary nutrition education program. Am J Health Promot (1999) 1.59
Capsule production and growth phase influence binding of complement to Staphylococcus aureus. Infect Immun (2001) 1.59
Effectiveness of a continuous quality improvement program aiming to reduce unplanned extubation: a prospective study. Intensive Care Med (1996) 1.58
Glycolysis and methylaminoisobutyrate uptake in rat-1 cells transfected with ras or myc oncogenes. Proc Natl Acad Sci U S A (1985) 1.58
Identification of ribosomal protein autoantigens. J Immunol (1985) 1.57
The in vitro perfused pancreas. Methods Enzymol (1975) 1.56
Characterization of the effects of arginine and glucose on glucagon and insulin release from the perfused rat pancreas. J Clin Invest (1974) 1.55
AA.AG@helix.ends: A:A and A:G base-pairs at the ends of 16 S and 23 S rRNA helices. J Mol Biol (2001) 1.54
Pelvic support defects and visceral and sexual function in women treated with sacrospinous ligament suspension and pelvic reconstruction. Am J Obstet Gynecol (1996) 1.54
Laryngeal chemosensitivity: a possible mechanism for sudden infant death. Pediatrics (1975) 1.54
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. J Pharmacol Exp Ther (2001) 1.54
The effect of acute hypoxia and hypercapnia on the ultrastructure of the central nervous system. Brain (1968) 1.52
Preferential solvent interactions between proteins and polyethylene glycols. J Biol Chem (1981) 1.52
Disseminated mixed Mycobacterium simiae-Mycobacterium avium complex infection in acquired immunodeficiency syndrome. J Infect Dis (1991) 1.52