Published in Proc Natl Acad Sci U S A on April 09, 2002
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TLR2 signaling improves immunoregulation to prevent type 1 diabetes. Eur J Immunol (2011) 0.89
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99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: immune therapies of type 1 diabetes: new opportunities based on the hygiene hypothesis. Clin Exp Immunol (2010) 0.87
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: viruses, autoimmunity and immunoregulation. Clin Exp Immunol (2010) 0.85
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A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet (2004) 12.25
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes. Proc Natl Acad Sci U S A (2007) 6.44
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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature (2005) 5.39
Timing of initial cereal exposure in infancy and risk of islet autoimmunity. JAMA (2003) 4.00
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA (2013) 3.65
Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA (2005) 3.61
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration. Gastroenterology (2005) 3.56
Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol (2006) 3.55
A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity (2005) 3.07
O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding. Science (2010) 2.98
Infant exposures and development of type 1 diabetes mellitus: The Diabetes Autoimmunity Study in the Young (DAISY). JAMA Pediatr (2013) 2.92
Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care (2009) 2.91
Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice. J Clin Invest (2007) 2.81
Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis. J Am Soc Nephrol (2008) 2.74
Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia. J Clin Endocrinol Metab (2010) 2.70
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The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results. Pediatr Diabetes (2008) 2.60
Signature microRNA expression profile of essential hypertension and its novel link to human cytomegalovirus infection. Circulation (2011) 2.60
A prospective study of the incidence of childhood celiac disease. J Pediatr (2003) 2.50
Elimination of maternally transmitted autoantibodies prevents diabetes in nonobese diabetic mice. Nat Med (2002) 2.29
Dystroglycan function requires xylosyl- and glucuronyltransferase activities of LARGE. Science (2012) 2.22
Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY). J Clin Endocrinol Metab (2004) 2.19
A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes. Diabetes (2008) 2.09
The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension. Cardiovasc Res (2013) 2.08
Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes. JAMA (2007) 2.04
Insulin as an autoantigen in NOD/human diabetes. Curr Opin Immunol (2008) 1.95
A report on the International Transglutaminase Autoantibody Workshop for Celiac Disease. Am J Gastroenterol (2009) 1.94
Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screening. Diabetes (2008) 1.90
Extreme genetic risk for type 1A diabetes. Proc Natl Acad Sci U S A (2006) 1.90
Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A (2010) 1.87
Age of islet autoantibody appearance and mean levels of insulin, but not GAD or IA-2 autoantibodies, predict age of diagnosis of type 1 diabetes: diabetes autoimmunity study in the young. Diabetes Care (2011) 1.86
Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex. Diabetes (2007) 1.84
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol (2006) 1.82
Resveratrol prevents the development of pathological cardiac hypertrophy and contractile dysfunction in the SHR without lowering blood pressure. Am J Hypertens (2009) 1.82
MRI findings of primary CNS lymphoma in 26 immunocompetent patients. Korean J Radiol (2010) 1.79
Investigation of the role of B-cells in type 1 diabetes in the NOD mouse. Diabetes (2004) 1.76
Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse. Proc Natl Acad Sci U S A (2003) 1.75
Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays. Clin Immunol (2007) 1.75
How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes (2011) 1.74
Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention. Immunity (2002) 1.74
Therapeutic targeting of Syk in autoimmune diabetes. J Immunol (2010) 1.69
Network for Pancreatic Organ Donors with Diabetes (nPOD): developing a tissue biobank for type 1 diabetes. Diabetes Metab Res Rev (2012) 1.68
Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY). Diabetes (2010) 1.67
Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up. Diabetes Care (2004) 1.65
Impact of celiac autoimmunity on children with type 1 diabetes. J Pediatr (2007) 1.64
Absence of transfusion-associated microchimerism in pediatric and adult recipients of leukoreduced and gamma-irradiated blood components. Transfusion (2011) 1.59
Celiac autoimmunity in children with type 1 diabetes: a two-year follow-up. J Pediatr (2011) 1.57
SGK196 is a glycosylation-specific O-mannose kinase required for dystroglycan function. Science (2013) 1.57
Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes. J Clin Endocrinol Metab (2003) 1.55
Distinguishing persistent insulin autoantibodies with differential risk: nonradioactive bivalent proinsulin/insulin autoantibody assay. Diabetes (2011) 1.53
Structure of the N-terminal RNA-binding domain of the SARS CoV nucleocapsid protein. Biochemistry (2004) 1.53
Concordance for islet autoimmunity among monozygotic twins. N Engl J Med (2008) 1.53
Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J Exp Med (2003) 1.52
Enhanced ascertainment of microchimerism with real-time quantitative polymerase chain reaction amplification of insertion-deletion polymorphisms. Transfusion (2006) 1.50
WD40 repeat propellers define a ubiquitin-binding domain that regulates turnover of F box proteins. Mol Cell (2010) 1.50
In utero dietary exposures and risk of islet autoimmunity in children. Diabetes Care (2003) 1.49
Analysis of T-cell assays to measure autoimmune responses in subjects with type 1 diabetes: results of a blinded controlled study. Diabetes (2006) 1.49
Persistently autoantibody negative (PAN) type 1 diabetes mellitus in children. Pediatr Diabetes (2010) 1.48
Prevalence of autoantibody-negative diabetes is not rare at all ages and increases with older age and obesity. J Clin Endocrinol Metab (2006) 1.47
The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings. Pediatr Diabetes (2013) 1.46
Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis. J Clin Invest (2014) 1.46
Zinc transporter-8 autoantibodies improve prediction of type 1 diabetes in relatives positive for the standard biochemical autoantibodies. Diabetes Care (2012) 1.45
Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity. J Clin Invest (2007) 1.44
Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups. Diabetes Care (2005) 1.43
The role of transplacental microtransfusions of maternal lymphocytes in HIV transmission to newborns. AIDS (2008) 1.42
Analysis of pathogenesis of juvenile new-onset diabetes. J Diabetes (2011) 1.42