PubRank

D Colquhoun

Author PubWeight™ 177.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 On the stochastic properties of single ion channels. Proc R Soc Lond B Biol Sci 1981 11.30
2 Relaxation and fluctuations of membrane currents that flow through drug-operated channels. Proc R Soc Lond B Biol Sci 1977 10.37
3 Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. J Physiol 1985 9.25
4 On the stochastic properties of bursts of single ion channel openings and of clusters of bursts. Philos Trans R Soc Lond B Biol Sci 1982 7.45
5 Fluctuations in the microsecond time range of the current through single acetylcholine receptor ion channels. Nature 1981 7.16
6 Inward current channels activated by intracellular Ca in cultured cardiac cells. Nature 1981 6.62
7 A P2X purinoceptor expressed by a subset of sensory neurons. Nature 1995 4.86
8 ATP receptor-mediated synaptic currents in the central nervous system. Nature 1992 4.57
9 The actions of tubocurarine at the frog neuromuscular junction. J Physiol 1979 3.69
10 Conductance of channels opened by acetylcholine-like drugs in muscle end-plate. Nature 1975 3.64
11 The binding of labelled tetrodotoxin to non-myelinated nerve fibres. J Physiol 1972 3.60
12 Acetylcholine receptors: too many channels, too few functions. Science 1995 3.55
13 Ion channel block by acetylcholine, carbachol and suberyldicholine at the frog neuromuscular junction. Proc R Soc Lond B Biol Sci 1985 2.64
14 Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proc Biol Sci 1992 2.49
15 Asymptotic distributions of apparent open times and shut times in a single channel record allowing for the omission of brief events. Philos Trans R Soc Lond B Biol Sci 1992 2.32
16 An analysis of the action of a false transmitter at the neuromuscular junction. J Physiol 1977 2.29
17 A note on correlations in single ion channel records. Proc R Soc Lond B Biol Sci 1987 2.26
18 Single-channel activations and concentration jumps: comparison of recombinant NR1a/NR2A and NR1a/NR2D NMDA receptors. J Physiol 1998 2.26
19 Activation of N-methyl-D-aspartate receptors by L-glutamate in cells dissociated from adult rat hippocampus. J Physiol 1992 2.24
20 Properties of the human muscle nicotinic receptor, and of the slow-channel myasthenic syndrome mutant epsilonL221F, inferred from maximum likelihood fits. J Physiol 2003 1.99
21 Re-analysis of clinical trial of homoeopathic treatment in fibrositis. Lancet 1990 1.81
22 Complementary medicine in the medical curriculum. J R Soc Med 1997 1.75
23 The binding of tetrodotoxin and alpha-bungarotoxin to normal and denervated mammalian muscle. J Physiol 1974 1.73
24 Rectification of currents activated by nicotinic acetylcholine receptors in rat sympathetic ganglion neurones. J Physiol 1990 1.71
25 Single-channel currents from recombinant NMDA NR1a/NR2D receptors expressed in Xenopus oocytes. Proc Biol Sci 1996 1.65
26 Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour. J Physiol 1997 1.60
27 The interaction at equilibrium between tetrodotoxin and mammalian non-myelinated nerve fibres. J Physiol 1972 1.58
28 Effects of pravastatin in 3260 patients with unstable angina: results from the LIPID study. Lancet 2000 1.56
29 Mechanisms of activation of muscle nicotinic acetylcholine receptors and the time course of endplate currents. Annu Rev Physiol 1995 1.55
30 On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons. Proc R Soc Lond B Biol Sci 1988 1.52
31 Mechanisms of activation of glutamate receptors and the time course of excitatory synaptic currents. Annu Rev Physiol 1995 1.51
32 Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells. J Physiol 1991 1.51
33 Conductances of single ion channels opened by nicotinic agonists are indistinguishable. Nature 1984 1.50
34 Mechanisms of drug action at the voluntary muscle endplate. Annu Rev Pharmacol 1975 1.49
35 Desensitization of the acetylcholine receptor of frog end-plates measured in a Vaseline-gap voltage clamp. J Physiol 1989 1.48
36 Block of acetylcholine-activated ion channels by an uncharged local anaesthetic. Nature 1981 1.47
37 The action of ganglionic blocking drugs on the synaptic responses of rat submandibular ganglion cells. Br J Pharmacol 1982 1.46
38 The modes of action of gallamine. Proc R Soc Lond B Biol Sci 1981 1.45
39 Single-channel and whole-cell currents evoked by acetylcholine in dissociated sympathetic neurons of the rat. Proc R Soc Lond B Biol Sci 1987 1.40
40 The kinetics of the interaction between tetrodotoxin and mammalian nonmyelinated nerve fibers. Mol Pharmacol 1972 1.39
41 The ion channel properties of a rat recombinant neuronal nicotinic receptor are dependent on the host cell type. J Physiol 1997 1.36
42 Effects of inhibitors of the binding of iodinated alpha-bungarotoxin to acetylcholine receptors in rat muscle. Mol Pharmacol 1976 1.36
43 Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors. Proc Biol Sci 1995 1.35
44 Glutamate activation of a single NMDA receptor-channel produces a cluster of channel openings. Proc Biol Sci 1991 1.34
45 Conductance and kinetic properties of single nicotinic acetylcholine receptor channels in rat sympathetic neurones. J Physiol 1991 1.33
46 Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors. J Neurosci 1998 1.32
47 Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes. J Physiol 1994 1.27
48 Deactivation and desensitization of non-NMDA receptors in patches and the time course of EPSCs in rat cerebellar granule cells. J Physiol 1996 1.26
49 The efficacy of agonists at the frog neuromuscular junction studied with single channel recording. Pflugers Arch 1983 1.23
50 Expression of cloned receptor subunits produces multiple receptors. Proc Biol Sci 1990 1.21
51 A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor. J Biol Chem 1998 1.21
52 Properties of human glycine receptors containing the hyperekplexia mutation alpha1(K276E), expressed in Xenopus oocytes. J Physiol 1998 1.20
53 Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat. J Physiol 1991 1.17
54 Rapid decay of averaged single-channel NMDA receptor activations recorded at low agonist concentration. Proc Biol Sci 1992 1.17
55 Rapid histamine assays: a method and some theoretical considerations. Br J Pharmacol 1970 1.14
56 Single channel properties of cloned NMDA receptors in a human cell line: comparison with results from Xenopus oocytes. J Physiol 1994 1.14
57 Long-term risk stratification for survivors of acute coronary syndromes. Results from the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study. LIPID Study Investigators. J Am Coll Cardiol 2001 1.14
58 Passive sensitization of skin and lung by guinea-pig immunoglobulins. Immunology 1965 1.13
59 Adsorption and diffusion of gamma-globulin during passive sensitization of chopped guinea-pig lung. J Physiol 1965 1.12
60 The action of tubocurarine at the neuromuscular junction [proceedings]. J Physiol 1978 1.05
61 Recessive inheritance and variable penetrance of slow-channel congenital myasthenic syndromes. Neurology 2002 1.04
62 The binding of labelled tetrodotoxin and cobra toxin by the rat diaphragm. Br J Pharmacol 1973 1.03
63 Molecular pharmacology. The binding issue. Nature 1993 1.02
64 The rate of equilibration in a competitive n drug system and the auto-inhibitory equations of enzyme kinetics: some properties of simple models for passive sensitization. Proc R Soc Lond B Biol Sci 1968 1.01
65 Activation of ion channels in the frog endplate by several analogues of acetylcholine. J Physiol 1991 1.00
66 Kinetics of acetylcholine activated ion channels in chick ciliary ganglion neurones grown in tissue culture. Pflugers Arch 1984 0.98
67 Single channel analysis of a novel NMDA channel from Xenopus oocytes expressing recombinant NR1a, NR2A and NR2D subunits. J Physiol 2000 0.92
68 Single-channel analysis of an NMDA receptor possessing a mutation in the region of the glutamate binding site. J Physiol 2000 0.92
69 Heterogeneity of neuronal nicotinic acetylcholine receptors in thin slices of rat medial habenula. J Physiol 1995 0.91
70 The effect of tubocurarine competition on the kinetics of agonist action on the nicotinic receptor. Br J Pharmacol 1982 0.89
71 Single channel analysis costs time. Trends Pharmacol Sci 1988 0.88
72 The actions of suxamethonium (succinyldicholine) as an agonist and channel blocker at the nicotinic receptor of frog muscle. J Physiol 1990 0.88
73 Leptin, but not adiponectin, is a predictor of recurrent cardiovascular events in men: results from the LIPID study. Int J Obes (Lond) 2008 0.87
74 Squash racquets. A review of physiology and medicine. Sports Med 1997 0.85
75 Competitive block and ion channel block as mechanisms of antagonist action on the skeletal muscle end-plate. Adv Biochem Psychopharmacol 1980 0.82
76 Voluntary partial retraction of: Recessive inheritance and variable penetrance of slow-channel congenital myasthenic syndromes. Neurology 2009 0.81
77 Molecular neurobiology. A new type of ion-channel block. Nature 1987 0.81
78 Modes of action of gallamine at the neuromuscular junction [proceedings]. Br J Pharmacol 1979 0.80
79 A comparative study of the efficacy of simvastatin and gemfibrozil in combined hyperlipoproteinemia: prediction of response by baseline lipids, apo E genotype, lipoprotein(a) and insulin. Atherosclerosis 1997 0.80
80 Unravelling the paradox. Trends Pharmacol Sci 1992 0.78
81 Is NADH effective in the treatment of chronic fatigue syndrome? Ann Allergy Asthma Immunol 2000 0.78
82 Neher and Sakmann win Nobel Prize for patch-clamp work. Trends Pharmacol Sci 1991 0.78
83 Kinetic effects of tubocurarine on skeletal muscle at high agonist concentrations [proceedings]. Br J Pharmacol 1980 0.78
84 Atlantic salmon bath challenged with Moritella viscosa--pathogen invasion and host response. Fish Shellfish Immunol 2009 0.77
85 The binding of tritium-labelled tetrodotoxin to non-myelinated nerve. J Physiol 1972 0.75
86 Proceedings: Tetrodotoxin binding to innervated and denervated rat diaphragm homogenates. Br J Pharmacol 1974 0.75
87 Analysis of end-plate current fluctuations produced by acetylcholine and acetylmonoethylcholine in rat muscle [proceedings]. Br J Pharmacol 1976 0.75
88 Proceedings: The inhibition of alpha-bungarotoxin binding to denervated rat muscle by tubocurarine and other drugs. Br J Pharmacol 1974 0.75
89 Health education, health promotion or drugs? Cholesterol and coronary heart disease. Med J Aust 1990 0.75
90 GABA and the single oocyte: relating binding to gating. Nat Neurosci 1999 0.75
91 Ion channels: this year's Nobel prize in physiology or medicine. BMJ 1991 0.75
92 Skin test reactivity and cellular immune responses to Mycobacterium avium sensitin in AIDS patients at risk for disseminated M. avium infection. Clin Diagn Lab Immunol 2001 0.75
93 How long does a molecule stay on the receptor? Explanation of a paradox. Br J Pharmacol 1970 0.75
94 Better Health Commission. Med J Aust 1985 0.75
95 Persistence: a new statistic for characterizing ion-channel activity. Philos Trans R Soc Lond B Biol Sci 1995 0.75
96 Molecular pharmacology: structure and function of acetylcholine-receptor ion channels. Nature 1986 0.75
97 Real-time PCR detection of Moritella viscosa, the likely causal agent of winter-ulcer in Atlantic salmon Salmo salar and rainbow trout Oncorhynchus mykiss. Dis Aquat Organ 2008 0.75
98 Vitamin use in clinical medicine. Med J Aust 1987 0.75
99 Modification of cardiovascular risk factors. Med J Aust 1988 0.75
100 Management of hypercholesterolaemia in postmenopausal women. Med J Aust 1989 0.75