Published in Lancet on October 24, 1981
The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity. Am J Hum Genet (1983) 3.23
Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am J Hum Genet (1995) 1.42
Simulation studies of segregation analysis: application to two-locus models. Am J Hum Genet (1984) 1.36
Heterozygous expression of insulin-dependent diabetes mellitus (IDDM) determinants in the HLA system. Am J Hum Genet (1983) 1.25
Genetic heterogeneity of insulin-dependent (type I) diabetes mellitus: evidence from a study of extended haplotypes. Am J Hum Genet (1984) 0.89
The use of association data to identify family members at high risk for marker-linked diseases. Am J Hum Genet (1984) 0.80
Detection of genetic heterogeneity between families of insulin-dependent diabetes mellitus patients using linkage analysis. Am J Hum Genet (1985) 0.75
A combined segregation and linkage analysis of insulin-dependent diabetes mellitus. Am J Hum Genet (1987) 0.75
HLA-associated diseases: a new method for performing linkage analysis with other markers than HLA. Am J Hum Genet (1984) 0.75
A new methodology for analysis of HLA-associated diseases? Am J Hum Genet (1983) 0.75
High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med (1973) 9.90
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Serotyping for homotransplantation. 18. Refinement of microdroplet lymphocyte cytotoxicity test. Transplantation (1968) 8.51
The use of cyclosporin A and prednisone in cadaver kidney transplantation. Surg Gynecol Obstet (1980) 7.40
Report of the Committee on the Genetic Constitution of Chromosomes 7, 8 and 9. Cytogenet Cell Genet (1985) 7.28
Microdroplet testing for HLA-A, -B, -C, and -D antigens. The Phillip Levine Award Lecture. Am J Clin Pathol (1978) 6.88
Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility. Nature (1991) 6.17
Extensions to pedigree analysis. III. Variance components by the scoring method. Ann Hum Genet (1976) 5.86
Significance of the positive crossmatch test in kidney transplantation. N Engl J Med (1969) 5.50
HLA-DR effects in a large German IDDM dataset. Genet Epidemiol Suppl (1986) 5.41
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell (1993) 5.37
Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science (1981) 5.28
Loss of information due to ambiguous haplotyping of SNPs. Nat Genet (1999) 4.90
Autologous stimulation of human lymphocyte subpopulation. J Exp Med (1975) 4.80
Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness. Nat Genet (1993) 4.49
Some epistatic two-locus models of disease. I. Relative risks and identity-by-descent distributions in affected sib pairs. Am J Hum Genet (1981) 4.49
Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D. Science (1983) 4.43
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet (2000) 4.42
Cytotoxins in disease. Autocytotoxins in lupus. N Engl J Med (1970) 4.40
Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor. Ann Intern Med (1986) 4.18
Serotyping for homotransplantation. X. Survival of 196 grafted kidneys subsequent to typing. Transplantation (1967) 4.16
Shwartzman reaction after human renal homotransplantation. N Engl J Med (1968) 4.05
Kidney preservation for transportation. Initial perfusion and 30 hours' ice storage. Lancet (1969) 3.67
Beta glucuronidase deficiency: report of clinical, radiologic, and biochemical features of a new mucopolysaccharidosis. J Pediatr (1973) 3.44
Effect of blood transfusions on subsequent kidney transplants. Transplant Proc (1973) 3.42
Chimerism after liver transplantation for type IV glycogen storage disease and type 1 Gaucher's disease. N Engl J Med (1993) 3.36
The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity. Am J Hum Genet (1983) 3.23
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
Effect of pravastatin on outcomes after cardiac transplantation. N Engl J Med (1995) 3.11
The information contained in multiple sibling pairs. Genet Epidemiol (1984) 3.10
Perinuclear antineutrophil cytoplasmic antibodies in patients with Crohn's disease define a clinical subgroup. Gastroenterology (1996) 3.08
Mental retardation associated with "balanced" chromosome rearrangements. Am J Hum Genet (1977) 3.06
Relationships among serum pepsinogen I, serum pepsinogen II, and gastric mucosal histology. A study in relatives of patients with pernicious anemia. Gastroenterology (1982) 3.05
Chronic survival after human renal homotransplantation. Lymphocyte-antigen matching, pathology and influence of thymectomy. Ann Surg (1965) 3.00
Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3. Nat Genet (1995) 2.93
Genetic and clinical heterogeneity in the oral-facial-digital syndromes. J Pediatr (1967) 2.92
Adequacy of single-locus approximations for linkage analyses of oligogenic traits. Genet Epidemiol (1992) 2.89
Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11q. Nature (1994) 2.82
Family history: a comprehensive genetic risk assessment method for the chronic conditions of adulthood. Am J Med Genet (1997) 2.79
Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science (1983) 2.78
The power to detect linkage in complex disease by means of simple LOD-score analyses. Am J Hum Genet (1998) 2.74
Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14. Science (1980) 2.72
Familial expression of anti-Saccharomyces cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease. Gut (2000) 2.71
A simple method to detect linkage for rare recessive diseases: an application to juvenile diabetes. Clin Genet (1979) 2.70
Pachydermoperiostosis: an update. Clin Genet (2005) 2.65
Genetic heterogeneity of hyperpepsinogenemic I and normopepsinogenemic I duodenal ulcer disease. Ann Intern Med (1979) 2.61
Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest (1997) 2.57
Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene. Nat Genet (1995) 2.55
Intestinal permeability in patients with Crohn's disease and their healthy relatives. Gastroenterology (1989) 2.55
Improvement of kidney-graft survival with increased numbers of blood transfusions. N Engl J Med (1978) 2.52
Cellulose acetate electrophoresis of human glucose-6-phosphate dehydrogenase. J Lab Clin Med (1969) 2.49
Transplantation of kidneys from donors whose hearts have stopped beating. N Engl J Med (1998) 2.48
Association of primary sclerosing cholangitis with HLA-DRw52a. N Engl J Med (1990) 2.40
The human retinal degeneration slow (RDS) gene: chromosome assignment and structure of the mRNA. Genomics (1991) 2.39
Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. Gut (1993) 2.35
Thoracic duct drainage before and after cadaveric kidney transplantation. Surg Gynecol Obstet (1979) 2.33
Heterologous antilymphocyte glubulin, histoincompatiblity matching, and human renal homotransplantation. Surg Gynecol Obstet (1968) 2.23
Direct evidence for a bone marrow origin of the alveolar macrophage in man. Science (1976) 2.23
Wolfram syndrome: a mitochondrial-mediated disorder? Lancet (1993) 2.22
The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. Am J Hum Genet (2004) 2.21
PARP alleles within the linked chromosomal region are associated with systemic lupus erythematosus. J Clin Invest (1999) 2.14
The relative effects of FK506 and cyclosporine on short- and long-term kidney graft survival. Transplantation (1995) 2.13
Regional assignment of the steroid sulfatase-X-linked ichthyosis locus: implications for a noninactivated region on the short arm of human X chromosome. Proc Natl Acad Sci U S A (1979) 2.13
Linkage analysis of neurofibromatosis (von Recklinghausen disease). J Med Genet (1983) 2.13
The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J Biol Chem (1987) 2.13
Equitable allocation of HLA-compatible kidneys for local pools and minorities. N Engl J Med (1994) 2.12
Reactivity of lymphocytes from normal persons on cultured tumor cells. Cancer Res (1973) 2.11
A robust method for the detection of linkage in familial disease. Am J Hum Genet (1978) 2.10
Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease. Genomics (1989) 2.10
Survival of nationally shared, HLA-matched kidney transplants from cadaveric donors. The UNOS Scientific Renal Transplant Registry. N Engl J Med (1992) 2.09
The G deletion syndromes. J Pediatr (1970) 2.09
Association mapping of disease loci, by use of a pooled DNA genomic screen. Am J Hum Genet (1997) 2.07
Metaphyseal chondrodysplasia, Schmid type. Clinical and radiographic delineation with a review of the literature. Pediatr Radiol (1988) 2.06
Human renal transplants. I. Glomerular changes. Lab Invest (1967) 2.06
Characterization of sialosylated Lewisx as a new tumor-associated antigen. Cancer Res (1984) 2.02
The probability of obtaining compatible blood from related directed donors. Arch Pathol Lab Med (1990) 2.01
Autism and genetics. A decade of research. Arch Gen Psychiatry (1988) 2.00
Expression of an X-linked gene from an inactive human X chromosome in mouse-human hybrid cells: further evidence for the noninactivation of the steroid sulfatase locus in man. Proc Natl Acad Sci U S A (1980) 2.00
Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis. Hum Mol Genet (1996) 1.93
Inherent intractability of the ascertainment problem for pedigree data: a general likelihood framework. Am J Hum Genet (1995) 1.92
Inter- and intrafamilial heterogeneity: effective sampling strategies and comparison of analysis methods. Am J Hum Genet (1992) 1.91
Affecteds-only linkage methods are not a panacea. Am J Hum Genet (1996) 1.90
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89