Published in Science on May 30, 1980
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc Natl Acad Sci U S A (1990) 4.06
A primary genetic map of chromosome 13q. Am J Hum Genet (1986) 4.01
Homozygous deletion of the alpha- and beta 1-interferon genes in human leukemia and derived cell lines. Proc Natl Acad Sci U S A (1988) 3.67
Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas. Proc Natl Acad Sci U S A (1986) 2.30
Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants. Proc Natl Acad Sci U S A (1988) 2.22
Assignment of the gene for Wilson disease to chromosome 13: linkage to the esterase D locus. Proc Natl Acad Sci U S A (1985) 2.00
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Molecular etiology of low-penetrance retinoblastoma in two pedigrees. Am J Hum Genet (1993) 1.29
Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79. Proc Natl Acad Sci U S A (1988) 1.27
Mapping the Wilson disease locus to a cluster of linked polymorphic markers on chromosome 13. Am J Hum Genet (1987) 1.24
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Location of the retinoblastoma susceptibility gene(s) and the human esterase D locus. J Med Genet (1984) 1.15
Evidence for the close linkage between lymphocyte cytosol polypeptide with molecular weight of 64,000 (LCP1) and esterase D. Am J Hum Genet (1985) 1.12
Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome. Am J Hum Genet (1982) 1.10
Purification, biochemical characterization, and biological function of human esterase D. Proc Natl Acad Sci U S A (1986) 1.09
Eight closely linked loci place the Wilson disease locus within 13q14-q21. Am J Hum Genet (1988) 1.07
Application of intragenic DNA probes in prenatal screening for retinoblastoma gene carriers in the United Kingdom. Arch Dis Child (1990) 1.07
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Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma. Proc Natl Acad Sci U S A (1986) 1.04
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The need to screen all retinoblastoma patients for esterase D activity: detection of submicroscopic chromosome deletions. Arch Dis Child (1987) 0.98
Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line. Mol Cell Biol (1989) 0.98
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Lack of expression of aminoacylase-1 in small cell lung cancer. Evidence for inactivation of genes encoded by chromosome 3p. J Clin Invest (1989) 0.95
An assessment of the usefulness of electrophoretic variants of esterase-D in the antenatal diagnosis of retinoblastoma in the United Kingdom. Br J Cancer (1987) 0.93
Restriction fragment length polymorphism studies show consistent loss of chromosome 3p alleles in small cell lung cancer patients' tumors. J Clin Invest (1988) 0.90
A sialic acid-specific O-acetylesterase in human erythrocytes: possible identity with esterase D, the genetic marker of retinoblastomas and Wilson disease. Proc Natl Acad Sci U S A (1986) 0.90
Application of linkage analysis to genetic counselling in families with hereditary retinoblastoma. J Med Genet (1988) 0.89
Mapping the gene for X-linked cataracts and microcornea with facial, dental, and skeletal features to Xp22: an appraisal of the Nance-Horan syndrome. Trans Am Ophthalmol Soc (1989) 0.88
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Family studies on the chromosomal location of the retinoblastoma gene (Rb-1). J Med Genet (1982) 0.87
Retinoblastoma gene mutations in primary human bladder cancer. Br J Cancer (1995) 0.87
Colonic aberrant crypts in azoxymethane-treated F344 rats have decreased hexosaminidase activity. Am J Pathol (1990) 0.84
Application of PCR amplification of DNA from paraffin embedded tissue sections to linkage analysis in familial retinoblastoma. J Med Genet (1991) 0.82
Trilateral retinoblastoma in transgenic mice. Trans Am Ophthalmol Soc (1989) 0.81
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Translocation X;13 in a patient with retinoblastoma. J Med Genet (1987) 0.79
Aniridia and mental retardation with deletion of the short arm of chromosome 11. Trans Am Ophthalmol Soc (1981) 0.79
Two types of putative preneoplastic lesions identified by hexosaminidase activity in whole-mounts of colons from F344 rats treated with carcinogen. Am J Pathol (1993) 0.79
Amplification and characterization of the retinoblastoma gene VNTR by PCR. Am J Hum Genet (1992) 0.78
An appraisal of the application of recombinant DNA techniques to chromosome defects. Biochem J (1985) 0.77
Retinoblastoma--clinical and genetic aspects: a review. J R Soc Med (1988) 0.75
Systematic identification of phenotypically enriched loci using a patient network of genomic disorders. BMC Genomics (2016) 0.75
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature (1983) 11.57
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Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell (1993) 5.37
Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science (1981) 5.28
Structural evidence for the authenticity of the human retinoblastoma gene. Science (1987) 4.67
Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D. Science (1983) 4.43
The chromosomal basis of human neoplasia. Science (1983) 4.26
The origin of man: a chromosomal pictorial legacy. Science (1982) 4.02
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Distinctive chromosomal abnormalities in histologic subtypes of non-Hodgkin's lymphoma. N Engl J Med (1982) 3.82
Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science (1989) 3.63
Retinoblastoma: clues to human oncogenesis. Science (1984) 3.43
Constitutive fragile sites and cancer. Science (1984) 3.30
Effect of Aluminum Hydroxide Sedimentation, Sand Filtration and Chlorination on the Virus of Poliomyelitis. Am J Public Health Nations Health (1942) 3.26
The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity. Am J Hum Genet (1983) 3.23
Retinoblastoma and subband deletion of chromosome 13. Am J Dis Child (1978) 3.11
Mental retardation associated with "balanced" chromosome rearrangements. Am J Hum Genet (1977) 3.06
Expression and amplification of the N-myc gene in primary retinoblastoma. Nature (1984) 2.99
Structural rearrangement of the retinoblastoma gene in human breast carcinoma. Science (1988) 2.83
Patient with 13 chromosome deletion: evidence that the retinoblastoma gene is a recessive cancer gene. Science (1983) 2.78
Cellulose acetate electrophoresis of human glucose-6-phosphate dehydrogenase. J Lab Clin Med (1969) 2.49
The human retinal degeneration slow (RDS) gene: chromosome assignment and structure of the mRNA. Genomics (1991) 2.39
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Direct evidence for a bone marrow origin of the alveolar macrophage in man. Science (1976) 2.23
Regional assignment of the steroid sulfatase-X-linked ichthyosis locus: implications for a noninactivated region on the short arm of human X chromosome. Proc Natl Acad Sci U S A (1979) 2.13
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The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J Biol Chem (1987) 2.13
Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease. Genomics (1989) 2.10
Expression of an X-linked gene from an inactive human X chromosome in mouse-human hybrid cells: further evidence for the noninactivation of the steroid sulfatase locus in man. Proc Natl Acad Sci U S A (1980) 2.00
Multiple recurrent genomic defects in follicular lymphoma. A possible model for cancer. N Engl J Med (1987) 1.94
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New chromosome techniques in the study of human neoplasia. Hum Pathol (1981) 1.82
Juvenile myoclonic epilepsy (JME) may be linked to the BF and HLA loci on human chromosome 6. Am J Med Genet (1988) 1.82
The characterization of high-resolution G-banded chromosomes of man. Chromosoma (1978) 1.79
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A high resolution in situ hybridization technique for the direct visualization of labeled G-banded early metaphase and prophase chromosomes. Cytogenet Cell Genet (1978) 1.75
A simple G-banding technique. Lancet (1973) 1.72
Familial retinoblastoma and chromosome 13 deletion transmitted via an insertional translocation. Science (1981) 1.70
Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3. Science (1988) 1.69
Heterochromatin, satellite DNA, and cell function. Structural DNA of eucaryotes may support and protect genes and aid in speciation. Science (1971) 1.67
Retinoblastoma and deletion D (14) syndrome. J Med Genet (1969) 1.65
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Anal atresia, eye anomalies, and an additional small abnormal acrocentric chromosome (47,XX,mar+): report of a case. J Pediatr (1970) 1.58
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Genetic and clinical studies in 13 patients with the Wolf-Hirschhorn syndrome [del(4p)]. Hum Genet (1981) 1.55
Bone marrow origin of hepatic macrophages (Kupffer cells) in humans. Science (1978) 1.53
Pericentric inversion of a number 15 chromosome in nine members of one family. Cytogenetics (1970) 1.51
Linkage of an autosomal dominant clefting syndrome (Van der Woude) to loci on chromosome Iq. Am J Hum Genet (1990) 1.48
De novo interstitial deletion in the long arm of chromosome 9: a new chromosome syndrome. J Med Genet (1982) 1.48
Huntington disease: linkage analysis with age-of-onset corrections. Am J Med Genet (1980) 1.46
Inherited partial duplication of chromosome No. 15. J Med Genet (1974) 1.45
Putative non-Mendelian transmission of retinoblastoma in males: a phenotypic segregation analysis of 150 pedigrees. Hum Genet (1994) 1.43
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D2 dopamine receptor gene and cigarette smoking: a reward gene? Med Hypotheses (1994) 1.42
Observation of a centrality-dependent dijet asymmetry in lead-lead collisions at sqrt[S(NN)] =2.76 TeV with the ATLAS detector at the LHC. Phys Rev Lett (2010) 1.41
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Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
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Cloning, expression and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3. Nucleic Acids Res (1992) 1.38
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Confirmation of linkage between juvenile myoclonic epilepsy locus and the HLA region of chromosome 6. Am J Med Genet (1991) 1.36
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A familial syndrome of deafness, alopecia, and hypogonadism. J Pediatr (1973) 1.34
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Satellite DNA in constitutive heterochromatin of the guinea pig. Science (1970) 1.32
Inherited pericentric inversion of chromosome no. 4. Am J Hum Genet (1970) 1.31
D2 dopamine receptor gene and obesity. Int J Eat Disord (1994) 1.30
Close genetic linkage between diabetes mellitus and kidd blood group. Lancet (1981) 1.30
All patients with acute nonlymphocytic leukemia may have a chromosomal defect. N Engl J Med (1981) 1.29
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Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Features of trisomy 18 and 18p- syndromes in an infant with 45,XY,i(18q). Clin Genet (1979) 1.27
Characterization of banding patterns of metaphase-prophase G-banded chromosomes and their use in gene mapping. Cytogenet Cell Genet (1978) 1.26
Fibrin overlay methods for the detection of single transformed cells and colonies of transformed cells. Cell (1975) 1.25
Late replication studies in a human X/13 translocation: correlation with autosomal gene expression. Cytogenet Cell Genet (1981) 1.25
Familial hypogonadotropic hypogonadism with anosmia. Arch Intern Med (1968) 1.24