Published in Ann Hum Genet on May 01, 1976
Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet (1998) 40.97
Robust variance-components approach for assessing genetic linkage in pedigrees. Am J Hum Genet (1994) 10.58
Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet (2001) 7.53
Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet (2006) 7.13
Genetic determination of telomere size in humans: a twin study of three age groups. Am J Hum Genet (1994) 7.04
Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage (2009) 3.66
Maximum likelihood estimation by counting methods under polygenic and mixed models in human pedigrees. Am J Hum Genet (1979) 3.36
Genetic determinants of bone mass in adults. A twin study. J Clin Invest (1987) 3.23
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results. Am J Hum Genet (1999) 2.88
Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components. Am J Hum Genet (2000) 2.40
An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians. J Clin Invest (1998) 2.18
A major quantitative-trait locus for mole density is linked to the familial melanoma gene CDKN2A: a maximum-likelihood combined linkage and association analysis in twins and their sibs. Am J Hum Genet (1999) 2.15
Broad and narrow heritabilities of quantitative traits in a founder population. Am J Hum Genet (2001) 2.12
Type 2 diabetes: evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. Proc Natl Acad Sci U S A (1999) 1.91
Heritability of subcortical and limbic brain volume and shape in multiplex-multigenerational families with schizophrenia. Biol Psychiatry (2014) 1.57
The genetic and environmental sources of body mass index variability: the Muscatine Ponderosity Family Study. Am J Hum Genet (1991) 1.37
Using the realized relationship matrix to disentangle confounding factors for the estimation of genetic variance components of complex traits. Genet Sel Evol (2010) 1.27
Assessment of parent-of-origin effects in linkage analysis of quantitative traits. Am J Hum Genet (2001) 1.26
Comparison of sequential and fixed-structure sampling of pedigrees in complex segregation analysis of a quantitative trait. Am J Hum Genet (1988) 1.23
Genotype-phenotype relationships in fragile X syndrome: a family study. Am J Hum Genet (1993) 1.18
Quantitative trait locus analysis of longitudinal quantitative trait data in complex pedigrees. Genetics (2005) 1.17
Etiological heterogeneity in the development of antisocial behavior: the Virginia Twin Study of Adolescent Behavioral Development and the Young Adult Follow-Up. Psychol Med (2007) 1.08
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. IV. Separation of polygene from common environment effects. Am J Hum Genet (1978) 1.08
Imputation methods for missing data for polygenic models. BMC Genet (2003) 1.06
Age-stratified heritability estimation in the Framingham Heart Study families. BMC Genet (2003) 1.04
Mapping quantitative traits in unselected families: algorithms and examples. Genet Epidemiol (2009) 1.00
Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population: Mexican Americans from San Antonio, TX. BMC Res Notes (2011) 0.99
Inheritance of total serum IgE (basal levels) in man. Am J Hum Genet (1987) 0.95
XM: association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol (2012) 0.93
Estimation of environmental and genetic components of quantitative traits with application to serum cholesterol levels. Am J Hum Genet (1981) 0.93
Path analysis of family resemblance with temporal trends: applications to height, weight, and Quetelet index in northeastern Brazil. Am J Hum Genet (1985) 0.90
A nonsynonymous SNP within PCDH15 is associated with lipid traits in familial combined hyperlipidemia. Hum Genet (2009) 0.89
A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. PLoS One (2012) 0.89
Sample-size guidelines for linkage analysis of a dominant locus for a quantitative trait by the method of lod scores. Am J Hum Genet (1990) 0.87
The mediating effect of parental neglect on adolescent and young adult anti-sociality: a longitudinal study of twins and their parents. Behav Genet (2010) 0.86
Timing and genetic rapport between growth in skeletal maturity and height around puberty: similarities and differences between girls and boys. Am J Hum Genet (1995) 0.86
Autosome-wide linkage analysis of hip structural phenotypes in the Old Order Amish. Bone (2008) 0.84
Testing separate families of segregation hypotheses: bootstrap methods. Am J Hum Genet (1989) 0.84
Does the PI polymorphism alone control alpha-1-antitrypsin expression? Am J Hum Genet (1987) 0.82
Genomewide scans of red cell indices suggest linkage on chromosome 6q23. J Med Genet (2006) 0.82
Models of population-based analyses for data collected from large extended families. Eur J Epidemiol (2010) 0.82
Fixed and random effects in the variation of the finger ridge count: a study of fragile-X families. Am J Hum Genet (1992) 0.82
Evidence for a major dominance component in the variation of serum pepsinogen I levels. Am J Hum Genet (1982) 0.79
A defense of path analysis in genetic epidemiology. Am J Hum Genet (1983) 0.79
Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood-ratio test and conditional score statistic. BMC Proc (2009) 0.78
Variable expression of familial dysbetalipoproteinemia in apolipoprotein E*2 (Lys146-->Gln) Allele carriers. J Clin Invest (1994) 0.78
Testing Models for the Contributions of Genes and Environment to Developmental Change in Adolescent Depression. Behav Genet (2015) 0.77
Family-based association test using normal approximation to gene dropping null distribution. BMC Proc (2014) 0.76
A Variance-Component Framework for Pedigree Analysis of Continuous and Categorical Outcomes. Stat Biosci (2009) 0.75
An Effective Method to Identify Heritable Components from Multivariate Phenotypes. PLoS One (2015) 0.75
Exploration of non-hierarchical classification methods combined with linkage analysis to identify loci influencing clusters of co-regulated transcripts. BMC Proc (2007) 0.75
Heritability estimation of osteoarthritis in the pig-tailed macaque (Macaca nemestrina) with a look toward future data collection. PeerJ (2014) 0.75
Including endophenotypes as covariates in variance component heritability and linkage analysis. BMC Genet (2005) 0.75
Quantitative trait locus analysis of hybrid pedigrees: variance-components model, inbreeding parameter, and power. BMC Genet (2007) 0.75
Heritability Estimation using Regression Models for Correlation. J Biom Biostat (2011) 0.75
Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data. Genet Epidemiol (2016) 0.75
Variance components linkage analysis with repeated measurements. Hum Hered (2008) 0.75
Genetic and environmental architecture of changes in episodic memory from middle to late middle age. Psychol Aging (2015) 0.75
Linkage analysis of systolic blood pressure: a score statistic and computer implementation. BMC Genet (2003) 0.75
Environmental index in genetic epidemiology: an investigation of its role, adequacy, and limitations. Am J Hum Genet (1990) 0.75
Twin birth changes DNA methylation of subsequent siblings. Sci Rep (2017) 0.75
Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet (1996) 17.95
Extensions to pedigree analysis I. Likehood calculations for simple and complex pedigrees. Hum Hered (1975) 16.67
Programs for Pedigree Analysis: MENDEL, FISHER, and dGENE. Genet Epidemiol (1988) 13.73
The affected-pedigree-member method of linkage analysis. Am J Hum Genet (1988) 13.67
Report of the Committee on the Genetic Constitution of Chromosomes 7, 8 and 9. Cytogenet Cell Genet (1985) 7.28
EM reconstruction algorithms for emission and transmission tomography. J Comput Assist Tomogr (1984) 6.54
Statistical analysis of multilocus recombination. Biometrics (1983) 6.49
An alternative model of recombination and interference. Ann Hum Genet (1979) 6.26
Estimating kinetic constants from single channel data. Biophys J (1983) 6.14
A conditional inference framework for extending the transmission/disequilibrium test. Hum Hered (1998) 5.70
How many polymorphic genes will it take to span the human genome? Am J Hum Genet (1982) 5.11
Loss of information due to ambiguous haplotyping of SNPs. Nat Genet (1999) 4.90
Computer programs for multilocus haplotyping of general pedigrees. Am J Hum Genet (1995) 4.51
Use of population isolates for mapping complex traits. Nat Rev Genet (2000) 4.28
An algorithm for automatic genotype elimination. Am J Hum Genet (1987) 4.18
Metropolis sampling in pedigree analysis. Stat Methods Med Res (1993) 4.04
Prostate cancer susceptibility locus on chromosome 1q: a confirmatory study. J Natl Cancer Inst (1997) 3.92
Localization of an ataxia-telangiectasia gene to chromosome 11q22-23. Nature (1988) 3.82
The role of early HIV infection in the spread of HIV through populations. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 3.75
Extensions to pedigree analysis. V. Optimal calculation of Mendelian likelihoods. Hum Hered (1983) 3.74
The affected sib-pair method using identity by state relations. Am J Hum Genet (1986) 3.63
Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers. Proc Natl Acad Sci U S A (1989) 3.50
The prior probability of autosomal linkage. Ann Hum Genet (1975) 3.45
A multipoint method for detecting genotyping errors and mutations in sibling-pair linkage data. Am J Hum Genet (2000) 3.22
Extensions to pedigree analysis. IV. Covariance components models for multivariate traits. Am J Med Genet (1983) 3.10
Mental retardation associated with "balanced" chromosome rearrangements. Am J Hum Genet (1977) 3.06
Statistical analysis of single sodium channels. Effects of N-bromoacetamide. Biophys J (1984) 3.01
Genetic heterogeneity of hyperpepsinogenemic I and normopepsinogenemic I duodenal ulcer disease. Ann Intern Med (1979) 2.61
EM algorithms without missing data. Stat Methods Med Res (1997) 2.39
The calcium scare--what would Austin Bradford Hill have thought? Osteoporos Int (2011) 2.35
The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. Am J Hum Genet (2004) 2.21
A single dominant gene can account for eye tracking dysfunctions and schizophrenia in offspring of discordant twins. Arch Gen Psychiatry (1988) 2.21
Statistical methods for multipoint radiation hybrid mapping. Am J Hum Genet (1991) 2.16
Fast computation of genetic likelihoods on human pedigree data. Hum Hered (1992) 2.15
Linkage analysis of neurofibromatosis (von Recklinghausen disease). J Med Genet (1983) 2.13
Localization of an ataxia-telangiectasia gene to an approximately 500-kb interval on chromosome 11q23.1: linkage analysis of 176 families by an international consortium. Am J Hum Genet (1995) 2.07
Application of a recombination model in calculating the variance of sib pair genetic identity. Ann Hum Genet (1979) 2.01
Autism and genetics. A decade of research. Arch Gen Psychiatry (1988) 2.00
Affecteds-only linkage methods are not a panacea. Am J Hum Genet (1996) 1.90
Ataxia-telangiectasia: an interdisciplinary approach to pathogenesis. Medicine (Baltimore) (1991) 1.89
Ascertainment and goodness of fit of variance component models for pedigree data. Prog Clin Biol Res (1984) 1.89
The process of tholin formation in Titan's upper atmosphere. Science (2007) 1.88
Nephritis caused by Streptococcus zooepidemicus (Lancefield group C). Lancet (1983) 1.86
Accurate and superaccurate gene mapping. Am J Hum Genet (1985) 1.85
Stimulation of human leukocyte thromboplastic activity by endotoxin. Proc Soc Exp Biol Med (1971) 1.79
Multipoint linkage map of the human pseudoautosomal region, based on single-sperm typing: do double crossovers occur during male meiosis? Am J Hum Genet (1994) 1.78
Some epistatic two-locus models of disease. II. The confounding of linkage and association. Am J Hum Genet (1981) 1.73
Quantitative-trait-locus analysis of body-mass index and of stature, by combined analysis of genome scans of five Finnish study groups. Am J Hum Genet (2001) 1.72
Genetics of essential hypertension. Am J Med (1993) 1.70
Routine immunohistology in renal diseases. Ann Intern Med (1966) 1.69
Ordering three DNA polymorphisms on human chromosome 3 by sperm typing. Genomics (1991) 1.69
The genetic transmission of schizophrenia: application of Mendelian latent structure analysis to eye tracking dysfunctions in schizophrenia and affective disorder. J Psychiatr Res (1986) 1.65
A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc Natl Acad Sci U S A (2001) 1.64
Autism and the serotonin transporter: the long and short of it. Mol Psychiatry (2005) 1.62
Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention. Proc Natl Acad Sci U S A (2000) 1.53
Evidence for multiple loci from a genome scan of autism kindreds. Mol Psychiatry (2006) 1.52
A new betaA1-crystallin splice junction mutation in autosomal dominant cataract. Invest Ophthalmol Vis Sci (2000) 1.50
Genetic analyses of pyloric stenosis suggesting a specific maternal effect. J Med Genet (1976) 1.49
Linkage of an autosomal dominant clefting syndrome (Van der Woude) to loci on chromosome Iq. Am J Hum Genet (1990) 1.48
Sensor-augmented pump therapy from the diagnosis of childhood type 1 diabetes: results of the Paediatric Onset Study (ONSET) after 12 months of treatment. Diabetologia (2010) 1.48
A theoretical study of some maximum likelihood algorithms for emission and transmission tomography. IEEE Trans Med Imaging (1987) 1.48
Genetic analysis of cleft lip with or without cleft palate in Danish kindreds. Am J Med Genet (1984) 1.48
HLA and the inheritance of multiple sclerosis: linkage analysis of 72 pedigrees. Am J Hum Genet (1980) 1.46
Huntington disease: linkage analysis with age-of-onset corrections. Am J Med Genet (1980) 1.46
Dopamine genes and ADHD. Neurosci Biobehav Rev (2000) 1.46
Preliminary ranking procedures for multilocus ordering. Genomics (1987) 1.45
Putative non-Mendelian transmission of retinoblastoma in males: a phenotypic segregation analysis of 150 pedigrees. Hum Genet (1994) 1.43
Multilocus ordering strategies based on sperm typing. Ann Hum Genet (1990) 1.40
Guidelines for human gene nomenclature. An international system for human gene nomenclature (ISGN, 1987). Cytogenet Cell Genet (1987) 1.40
Cleft lip with or without cleft palate in Shanghai, China: evidence for an autosomal major locus. Am J Hum Genet (1992) 1.38
Two models for a maternal factor in the inheritance of Huntington disease. Am J Hum Genet (1983) 1.37
A goodness-of-fit test for the polygenic threshold model: application to pyloric stenosis. Am J Med Genet (1978) 1.37
Application of the lod method to the detection of linkage between a quantitative trait and a qualitative marker: a simulation experiment. Am J Hum Genet (1976) 1.37
Confirmation of linkage between juvenile myoclonic epilepsy locus and the HLA region of chromosome 6. Am J Med Genet (1991) 1.36
Major gene determination of liability to cleft lip with or without cleft palate: a multiracial view. J Craniofac Genet Dev Biol Suppl (1986) 1.36
Possible heterogeneity in the segregation pattern of breast cancer in families with bilateral breast cancer. Genet Epidemiol (1988) 1.33
Approximate confidence intervals for risk prediction in genetic counseling. Am J Hum Genet (1986) 1.31
Close genetic linkage between diabetes mellitus and kidd blood group. Lancet (1981) 1.30
Gamete-competition models. Am J Hum Genet (2000) 1.28
A multilocus extension of the affected-pedigree-member method of linkage analysis. Am J Hum Genet (1992) 1.26
A genetic linkage map of the rat derived from recombinant inbred strains. Mamm Genome (1996) 1.25
A primary linkage map of the human chromosome 11q22-23 region. Genomics (1990) 1.25
Trials, tribulations, and triumphs of the EM algorithm in pedigree analysis. IMA J Math Appl Med Biol (1989) 1.25
Experimental design and error detection for polyploid radiation hybrid mapping. Genome Res (1995) 1.24
High prevalence of rare dopamine receptor D4 alleles in children diagnosed with attention-deficit hyperactivity disorder. Mol Psychiatry (2003) 1.24
A new class of organic nitrates: investigations on bioactivation, tolerance and cross-tolerance phenomena. Br J Pharmacol (2009) 1.24
Partial characterization of antigenic streptococcal plasma membrane components in acute glomerulonephritis. J Clin Invest (1970) 1.20
Effects of reproductive compensation and genetic drift on X-linked lethals. Am J Hum Genet (1978) 1.20
Ethanol stimulates formation of leukotriene C4 in rat gastric mucosa. Prostaglandins (1986) 1.19
Grouped-coordinate ascent algorithms for penalized-likelihood transmission image reconstruction. IEEE Trans Med Imaging (1997) 1.18
Penalized regression for genome-wide association screening of sequence data. Pac Symp Biocomput (2011) 1.17
Multipoint mapping calculations for sperm-typing data. Am J Hum Genet (1994) 1.16
Evidence for the in situ origin of poststreptococcal glomerulonephritis: glomerular localization of endostreptosin and the clinical significance of the subsequent antibody response. Clin Nephrol (1983) 1.16
Cleft lip with or without cleft palate: reanalysis of a three-generation family study from England. Genet Epidemiol (1986) 1.15
Genetic linkage analysis of autosomal dominant congenital cataracts. Am J Ophthalmol (1986) 1.15
Comments on lack of interference in the four strand model of crossing over. J Math Biol (1977) 1.15
Computational advances in maximum likelihood methods for molecular phylogeny. Genome Res (1998) 1.15
Relative-to-relative transition probabilities for two linked genes. Theor Popul Biol (1974) 1.13