Published in Cell on February 01, 1981
A catalogue of splice junction sequences. Nucleic Acids Res (1982) 39.41
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles. Microbiol Rev (1983) 24.58
In vitro mutagenesis of the promoter region for a vaccinia virus gene: evidence for tandem early and late regulatory signals. J Virol (1985) 5.77
A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome. EMBO J (1988) 3.69
Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids. Mol Cell Biol (1983) 3.63
Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression. Proc Natl Acad Sci U S A (1988) 3.11
Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA. Mol Cell Biol (1983) 3.00
Novel transcription map for the B19 (human) pathogenic parvovirus. J Virol (1987) 2.74
A measure of the similarity of sets of sequences not requiring sequence alignment. Proc Natl Acad Sci U S A (1986) 2.68
Amino acid sequence of the mRNA cap-binding protein from human tissues. Proc Natl Acad Sci U S A (1987) 2.61
Arrangement of late RNAs transcribed from a 7.1-kilobase EcoRI vaccinia virus DNA fragment. J Virol (1984) 2.48
Factors influencing alternative splice site utilization in vivo. Mol Cell Biol (1987) 2.39
Nucleotide sequence of the human parathyroid hormone gene. Proc Natl Acad Sci U S A (1983) 2.35
The genes coding for the cytoskeletal proteins actin and vimentin in warm-blooded vertebrates. EMBO J (1982) 2.30
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J (1996) 2.28
Complex regulation of simian virus 40 early-region transcription from different overlapping promoters. Mol Cell Biol (1984) 2.28
Relationship between the total size of exons and introns in protein-coding genes of higher eukaryotes. Proc Natl Acad Sci U S A (1982) 2.25
Analysis of the 5' regulatory region of the gene for delta-aminolevulinic acid synthetase of Rhizobium meliloti. Nucleic Acids Res (1985) 2.19
Characterization of the alpha-Amylases Synthesized by Aleurone Layers of Himalaya Barley in Response to Gibberellic Acid. Plant Physiol (1982) 2.15
Analysis of the mouse dhfr promoter region: existence of a divergently transcribed gene. Mol Cell Biol (1985) 2.02
Structure of transcripts from the homeotic Antennapedia gene of Drosophila melanogaster: two promoters control the major protein-coding region. Mol Cell Biol (1986) 2.00
A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon. Proc Natl Acad Sci U S A (1984) 2.00
The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters. EMBO J (1985) 1.95
Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. Proc Natl Acad Sci U S A (1989) 1.84
Alternative RNA splicing generates transcripts encoding a thorax-specific isoform of Drosophila melanogaster myosin heavy chain. Mol Cell Biol (1986) 1.69
Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression. Proc Natl Acad Sci U S A (1985) 1.62
Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis. J Clin Invest (1988) 1.60
Apocytochrome b and other mitochondrial DNA sequences are differentially expressed during the life cycle of Trypanosoma brucei. Nucleic Acids Res (1985) 1.57
The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species. Mol Cell Biol (1986) 1.54
Myosin light-chain 1 and 3 gene has two structurally distinct and differentially regulated promoters evolving at different rates. Mol Cell Biol (1985) 1.51
Structural features and restricted expression of a human alpha-tubulin gene. Nucleic Acids Res (1985) 1.51
Glucocorticoids and chromosomal position modulate murine mammary tumor virus transcription by affecting efficiency of promoter utilization. Mol Cell Biol (1983) 1.48
Enzymic mechanism of starch breakdown in germinating rice seeds : 12. Biosynthesis of alpha-amylase in relation to protein glycosylation. Plant Physiol (1982) 1.48
Epsilon globin gene transcripts originating upstream of the mRNA cap site in K562 cells and normal human embryos. Nucleic Acids Res (1982) 1.47
Effect of intron size on splicing efficiency in retroviral transcripts. Nucleic Acids Res (1982) 1.46
Differential expression of two distinct forms of mRNA encoding members of a dipeptidyl aminopeptidase family. Proc Natl Acad Sci U S A (1992) 1.43
Repeated consensus sequence and pseudopromoters in the four coordinately regulated tubulin genes of Chlamydomonas reinhardi. Mol Cell Biol (1984) 1.43
A new site of integration for mouse mammary tumor virus proviral DNA common to BALB/cf(C3H) mammary and kidney adenocarcinomas. EMBO J (1986) 1.39
Link protein cDNA sequence reveals a tandemly repeated protein structure. Proc Natl Acad Sci U S A (1986) 1.36
Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice. Mol Cell Biol (1987) 1.35
Differential expression of alternative 5' untranslated regions in mRNAs encoding rat insulin-like growth factor I. Proc Natl Acad Sci U S A (1987) 1.33
Xenopus laevis serum albumins are encoded in two closely related genes. Nucleic Acids Res (1981) 1.32
Chick pro alpha 2 (I) collagen gene: exon location and coding potential for the prepropeptide. Nucleic Acids Res (1983) 1.32
Sequence structures of a mouse major urinary protein gene and pseudogene compared. EMBO J (1985) 1.31
Isolation and characterization of the human parathyroid hormone-like peptide gene. Proc Natl Acad Sci U S A (1989) 1.31
Characterization of two atypical promoters and alternate mRNA processing in the mouse Thy-1.2 glycoprotein gene. Mol Cell Biol (1986) 1.28
Exogenous mouse mammary tumor virus proviral DNA isolated from a kidney adenocarcinoma cell line contains alterations in the U3 region of the long terminal repeat. J Virol (1986) 1.28
Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing. Proc Natl Acad Sci U S A (1986) 1.28
An unusual structure of a putative T cell oncogene which allows production of similar proteins from distinct mRNAs. EMBO J (1990) 1.27
Alternative processing of RNA transcribed from NMYC. Mol Cell Biol (1987) 1.26
Differential expression of mitochondrial genes between life cycle stages of Trypanosoma brucei. Proc Natl Acad Sci U S A (1985) 1.25
Calcitonin mRNA polymorphism: peptide switching associated with alternative RNA splicing events. Proc Natl Acad Sci U S A (1982) 1.22
Characterization of a genomic clone for rat seminal vesicle secretory protein IV. Nucleic Acids Res (1983) 1.22
Diverse patterns of expression of the cytochrome c oxidase subunit I gene and unassigned reading frames 4 and 5 during the life cycle of Trypanosoma brucei. Mol Cell Biol (1985) 1.22
Discrete human dihydrofolate reductase gene transcripts present in polysomal RNA map with their 5' ends several hundred nucleotides upstream of the main mRNA start site. Mol Cell Biol (1985) 1.20
Concerted evolution of human amylase genes. Mol Cell Biol (1988) 1.18
The nucleotide sequence of the chicken apo very low density lipoprotein II gene. Nucleic Acids Res (1983) 1.18
Sequence specificity of the post-translational proteolytic cleavage of vicilin, a seed storage protein of pea (Pisum sativum L.). Biochem J (1983) 1.16
Molecular cloning of a mouse submaxillary gland renin cDNA fragment. Proc Natl Acad Sci U S A (1981) 1.15
Cloning of two genes that are specifically expressed in activated cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1986) 1.14
Cloning exons of mapping of transcription: characterization of the Drosophila melanogaster alcohol dehydrogenase gene. Nucleic Acids Res (1983) 1.11
Tissue-specific expression of mRNAs for dipeptidyl carboxypeptidase isoenzymes. Proc Natl Acad Sci U S A (1982) 1.10
Human interferon gamma is encoded by a single class of mRNA. Nucleic Acids Res (1982) 1.10
Expression of pro-opiomelanocortin-like gene in the testis and epididymis. Proc Natl Acad Sci U S A (1984) 1.07
Construction of novel cytochrome b genes in yeast mitochondria by subtraction or addition of introns. EMBO J (1983) 1.07
Molecular cloning and the nucleotide sequence of cDNA to mRNA for non-neuronal enolase (alpha alpha enolase) of rat brain and liver. Nucleic Acids Res (1985) 1.06
Alternative 5' exons either provide or deny an initiator methionine codon to the same alpha-tubulin coding region. Nucleic Acids Res (1987) 1.05
Regulated expression of multiple chicken erythroid membrane skeletal protein 4.1 variants is governed by differential RNA processing and translational control. Proc Natl Acad Sci U S A (1987) 1.03
The mouse carbonic anhydrase I gene contains two tissue-specific promoters. Mol Cell Biol (1989) 1.03
Identification of two molecular-mass forms of phenylalanine hydroxylase that segregate independently in rats. Specific association of each form with certain rat strains. Biochem J (1984) 1.02
Positional and developmental regulation of glutamine synthetase expression in mouse liver. Mol Cell Biol (1988) 1.02
DNA sequence polymorphism in an androgen-regulated gene is associated with alteration in the encoded RNAs. Proc Natl Acad Sci U S A (1983) 1.01
Mammalian glutaminase Gls2 gene encodes two functional alternative transcripts by a surrogate promoter usage mechanism. PLoS One (2012) 1.01
Human Cu/Zn superoxide dismutase gene: molecular characterization of its two mRNA species. Nucleic Acids Res (1984) 1.00
Testis-specific transcription initiation sites of rat farnesyl pyrophosphate synthetase mRNA. Mol Cell Biol (1990) 1.00
Coordinate developmental regulation of high and low molecular weight mRNAs for rat insulin-like growth factor II. Proc Natl Acad Sci U S A (1986) 0.96
Identification and cell type specificity of the tyrosine hydroxylase gene promoter. Nucleic Acids Res (1987) 0.95
Coordination of murine parotid secretory protein and salivary amylase expression. EMBO J (1986) 0.94
Organisation of feather keratin genes in the chick genome. Nucleic Acids Res (1982) 0.91
Cytoplasmic RNA sequences complementary to cloned chick delta-crystallin cDNA show size heterogeneity. Biochem J (1982) 0.91
Structural characterization of a heterogeneous family of rat brain mRNAs. Mol Cell Biol (1986) 0.91
Isolation of an insulin-like growth factor II cDNA with a unique 5' untranslated region from human placenta. Proc Natl Acad Sci U S A (1988) 0.91
Alternative processing of bovine growth hormone mRNA: nonsplicing of the final intron predicts a high molecular weight variant of bovine growth hormone. Proc Natl Acad Sci U S A (1987) 0.90
Molecular cloning and nucleotide sequences of the complementary DNAs to chicken skeletal muscle myosin two alkali light chain mRNAs. Nucleic Acids Res (1982) 0.89
Transcription initiation sites and structural organization of the extreme 5' region of the rat neural cell adhesion molecule gene. Mol Cell Biol (1990) 0.88
Transduction of c-src coding and intron sequences by a transformation-defective deletion mutant of Rous sarcoma virus. J Virol (1986) 0.88
Different tissue-specific expression of the amylase gene Amy-1 in mice and rats. Mol Cell Biol (1986) 0.87
Different exon-intron organization at the 5' part of a mouse class I gene is used to generate a novel H-2Kd-related mRNA. Proc Natl Acad Sci U S A (1983) 0.87
Mouse brain CD4 transcripts encode only the COOH-terminal half of the protein. Mol Cell Biol (1988) 0.86
Alpha-amanitin insensitive transcription of the human epsilon-globin gene. Nucleic Acids Res (1985) 0.86
Simultaneous expression of salivary and pancreatic amylase genes in cultured mouse hepatoma cells. Mol Cell Biol (1986) 0.85
Differences in rates of tyrosine aminotransferase deinduction with cyclic AMP and glucocorticoids. Proc Natl Acad Sci U S A (1982) 0.85
Variation in amylase haplotypes among congenic lines of the house mouse. Genetics (1982) 0.84
Gene duplications in the TL region of the mouse major histocompatibility complex. EMBO J (1985) 0.83
A salivary amylase transgene is efficiently expressed in liver but not in parotid gland of transgenic mice. Nucleic Acids Res (1989) 0.81
Gene expression of the chondroitin sulfate proteoglycan core protein PG19. Mol Cell Biol (1987) 0.81
Two chicken erythrocyte band 3 mRNAs are generated by alternative transcriptional initiation and differential RNA splicing. Mol Cell Biol (1989) 0.81
Glucocorticoid and developmental regulation of amylase mRNAs in mouse liver cells. Mol Cell Biol (1988) 0.80
Multiple non-allelic genes encoding pancreatic alpha-amylase of mouse are expressed in a strain-specific fashion. EMBO J (1984) 0.80
Phosphoglucomutase 1: a gene with two promoters and a duplicated first exon. Biochem J (1993) 0.78
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
Genome-wide location and function of DNA binding proteins. Science (2000) 31.25
Dissecting the regulatory circuitry of a eukaryotic genome. Cell (1998) 23.62
Yeast RNA polymerase II genes: isolation with antibody probes. Science (1983) 17.91
A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell (1998) 10.92
Tissue-specific in vitro transcription from the mouse albumin promoter. Cell (1986) 10.54
Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell (2001) 9.63
Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells. Cell (1978) 8.98
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev (2000) 8.19
Serial regulation of transcriptional regulators in the yeast cell cycle. Cell (2001) 7.99
Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus. J Virol (1990) 7.90
A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell (1991) 7.64
Dissection of Mycobacterium tuberculosis antigens using recombinant DNA. Proc Natl Acad Sci U S A (1985) 7.46
Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science (2000) 6.55
Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae. Nature (1985) 6.54
Epitope tagging and protein surveillance. Methods Enzymol (1991) 6.47
An RNA polymerase II holoenzyme responsive to activators. Nature (1994) 6.22
The interplay of DNA-binding proteins on the promoter of the mouse albumin gene. Cell (1987) 6.14
Transcription of eukaryotic protein-coding genes. Annu Rev Genet (2000) 6.12
Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science (2001) 6.06
Stress proteins are immune targets in leprosy and tuberculosis. Proc Natl Acad Sci U S A (1988) 5.68
The plasticity of dendritic cell responses to pathogens and their components. Science (2001) 5.58
Efficient mapping of protein antigenic determinants. Proc Natl Acad Sci U S A (1986) 5.38
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell (1993) 5.35
Tissue-specific expression of mouse-alpha-amylase genes: nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland. Cell (1980) 5.25
Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver. Cell (1983) 5.22
LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein. Genes Dev (1990) 4.98
A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature (1995) 4.93
The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells. Cell (1978) 4.92
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev (2001) 4.91
Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA. Proc Natl Acad Sci U S A (1978) 4.90
Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast. Nature (1999) 4.71
Tissue-specific expression of mouse alpha-amylase genes. J Mol Biol (1980) 4.30
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli. Cell (1980) 4.19
Sequence of the 16 S-23 s spacer region in two ribosomal RNA operons of Escherichia coli. J Biol Chem (1979) 4.19
Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell (1987) 4.15
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol Cell (1998) 4.09
RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell (1996) 4.03
Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks. Pac Symp Biocomput (2001) 3.97
Prokaryotic and eukaryotic RNA polymerases have homologous core subunits. Proc Natl Acad Sci U S A (1987) 3.80
Oxpentifylline treatment of venous ulcers of the leg. BMJ (1990) 3.75
Human T-cell clones recognize a major M. leprae protein antigen expressed in E. coli. Nature (1986) 3.51
DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally. Cell (1990) 3.44
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev (1998) 3.42
Tandem promoters direct E. coli ribosomal RNA synthesis. Cell (1979) 3.36
RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Mol Cell Biol (1989) 3.21
Redundant roles for the TFIID and SAGA complexes in global transcription. Nature (2000) 3.21
Lambda gt 11: gene isolation with antibody probes and other applications. Methods Enzymol (1987) 3.17
Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts. Curr Biol (2000) 3.12
Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics (1989) 3.04
CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Proc Natl Acad Sci U S A (1993) 2.98
Multiple polyadenylation sites in a mouse alpha-amylase gene. Nucleic Acids Res (1981) 2.96
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP. Genes Dev (1993) 2.96
The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem Sci (1995) 2.96
Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res (2000) 2.91
General requirement for RNA polymerase II holoenzymes in vivo. Proc Natl Acad Sci U S A (1995) 2.88
The Fibres of Retiform Tissue. J Physiol (1892) 2.87
Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature (1995) 2.87
The role of cis-acting promoter elements in tissue-specific albumin gene expression. Science (1989) 2.86
CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. Genes Dev (2000) 2.84
Humoral and cell-mediated immune responses to live recombinant BCG-HIV vaccines. Nature (1991) 2.83
Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1. J Exp Med (1994) 2.81
Genes for the major protein antigens of Mycobacterium tuberculosis: the etiologic agents of tuberculosis and leprosy share an immunodominant antigen. Proc Natl Acad Sci U S A (1987) 2.79
Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro. J Biol Chem (1991) 2.76
Mouse liver and salivary gland alpha-amylase mRNAs differ only in 5' non-translated sequences. Nature (1981) 2.73
The etiologic agents of leprosy and tuberculosis share an immunoreactive protein antigen with the vaccine strain Mycobacterium bovis BCG. Infect Immun (1987) 2.66
The primary transcription product of a silkworm alanine tRNA gene: identification of in vitro sites of initiation, termination and processing. Cell (1979) 2.66
Gene replacement and expression of foreign DNA in mycobacteria. J Bacteriol (1990) 2.65
Association of an activator with an RNA polymerase II holoenzyme. Genes Dev (1995) 2.61
BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A (1997) 2.55
Transposition of the Escherichia coli insertion element gamma generates a five-base-pair repeat. Proc Natl Acad Sci U S A (1979) 2.47
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals. Nature (1990) 2.46
Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site. Cell (1984) 2.44
A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell (1995) 2.41
RNA polymerase II holoenzymes and subcomplexes. J Biol Chem (1998) 2.39
An activator target in the RNA polymerase II holoenzyme. Mol Cell (1998) 2.37
The ankle injury--indications for the selective use of X-rays. Injury (1983) 2.35
Physical isolation of nascent RNA chains transcribed by RNA polymerase II: evidence for cotranscriptional splicing. Mol Cell Biol (1994) 2.35
Characterization of antibody-reactive epitopes on the 65-kilodalton protein of Mycobacterium leprae. Infect Immun (1987) 2.30
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J (1996) 2.28
Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators. EMBO J (2001) 2.24
Selective suppression of the transcription of ribosomal genes in mouse-human hybrid cells. J Cell Physiol (1979) 2.21
Stress proteins may provide a link between the immune response to infection and autoimmunity. Int Immunol (1989) 2.21
Gene isolation by screening lambda gt11 libraries with antibodies. Methods Enzymol (1987) 2.20
Human T cell clones recognize two abundant Mycobacterium tuberculosis protein antigens expressed in Escherichia coli. J Immunol (1987) 2.19
Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm. Cell (1990) 2.19
T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection. J Immunol (1997) 2.18
The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior. EMBO J (1997) 2.17
A mammalian SRB protein associated with an RNA polymerase II holoenzyme. Nature (1996) 2.16
An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae. Mol Cell (1999) 2.14
Regulation of gene expression by TBP-associated proteins. Genes Dev (1998) 2.12
Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4. Genes Dev (1991) 2.10
Mapping of T cell epitopes using recombinant antigens and synthetic peptides. EMBO J (1987) 2.09