Published in Nucleic Acids Res on May 25, 1981
The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini. Nucleic Acids Res (1985) 7.18
cDNA cloning and induction of the alcohol dehydrogenase gene (Adh1) of maize. Proc Natl Acad Sci U S A (1982) 4.88
Degeneracy and complexity in biological systems. Proc Natl Acad Sci U S A (2001) 3.81
Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA. Proc Natl Acad Sci U S A (1986) 3.16
Identification of two human beta-tubulin isotypes. Mol Cell Biol (1983) 3.15
Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site. Mol Cell Biol (1984) 3.09
Requirement for the 3' flanking region of the bovine growth hormone gene for accurate polyadenylylation. Proc Natl Acad Sci U S A (1984) 2.58
Identification of sequences involved in the polyadenylation of higher plant nuclear transcripts using Agrobacterium T-DNA genes as models. EMBO J (1983) 2.53
Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA. Proc Natl Acad Sci U S A (1985) 2.44
Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites. Mol Cell Biol (1984) 2.35
Construction of a modular dihydrofolate reductase cDNA gene: analysis of signals utilized for efficient expression. Mol Cell Biol (1982) 2.33
The primary structure of a plant storage protein: zein. Nucleic Acids Res (1981) 2.27
The Drosophila melanogaster tropomyosin II gene produces multiple proteins by use of alternative tissue-specific promoters and alternative splicing. Mol Cell Biol (1988) 2.08
Human dopamine beta-hydroxylase gene: two mRNA types having different 3'-terminal regions are produced through alternative polyadenylation. Nucleic Acids Res (1989) 2.08
Sequence analysis of zein cDNAs obtained by an efficient mRNA cloning method. Nucleic Acids Res (1983) 2.05
GABAA receptor beta subunit heterogeneity: functional expression of cloned cDNAs. EMBO J (1989) 2.05
Characterization of the chicken vimentin gene: single copy gene producing multiple mRNAs. Proc Natl Acad Sci U S A (1983) 1.99
Isolation of an auxin-regulated gene cDNA expressed during the transition from G0 to S phase in tobacco mesophyll protoplasts. Proc Natl Acad Sci U S A (1989) 1.99
Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1. EMBO J (1986) 1.94
Proto-oncogene c-ros codes for a molecule with structural features common to those of growth factor receptors and displays tissue specific and developmentally regulated expression. Mol Cell Biol (1986) 1.88
Identification of sequences in the herpes simplex virus thymidine kinase gene required for efficient processing and polyadenylation. Mol Cell Biol (1985) 1.79
Multiple 3' ends of the chicken pro alpha 2(I) collagen gene. Nucleic Acids Res (1983) 1.61
The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species. Mol Cell Biol (1986) 1.54
Termination of the ovalbumin gene transcription. EMBO J (1984) 1.53
Structure of mouse major urinary protein genes: different splicing configurations in the 3'-non-coding region. EMBO J (1984) 1.41
The murine immunoglobulin alpha gene expresses multiple transcripts from a unique membrane exon. EMBO J (1983) 1.34
A 3' co-terminus of two early herpes simplex virus type 1 mRNAs. Nucleic Acids Res (1982) 1.33
Kinetics and efficiency of polyadenylation of late polyomavirus nuclear RNA: generation of oligomeric polyadenylated RNAs and their processing into mRNA. Mol Cell Biol (1984) 1.32
One of the tightly clustered genes of the mouse surfeit locus is a highly expressed member of a multigene family whose other members are predominantly processed pseudogenes. Mol Cell Biol (1988) 1.32
Molecular characterization of the testis specific c-abl mRNA in mouse. EMBO J (1987) 1.31
Genomic and cDNA actin sequences from a virulent strain of Entamoeba histolytica. Proc Natl Acad Sci U S A (1987) 1.30
Amino acid sequence of S-adenosyl-L-homocysteine hydrolase from rat liver as derived from the cDNA sequence. Proc Natl Acad Sci U S A (1987) 1.28
gamma Heavy chain disease in man: cDNA sequence supports partial gene deletion model. Proc Natl Acad Sci U S A (1982) 1.27
Molecular cloning and characterization of the glucoamylase gene of Aspergillus awamori. Mol Cell Biol (1984) 1.23
Human J chain gene. Structure and expression in B lymphoid cells. J Exp Med (1985) 1.23
Phenotypic expression in Escherichia coli and nucleotide sequence of two Chinese hamster lung cell cDNAs encoding different dihydrofolate reductases. Mol Cell Biol (1984) 1.21
Cloning and cDNA sequence of a bovine submaxillary gland mucin-like protein containing two distinct domains. Proc Natl Acad Sci U S A (1990) 1.20
Molecular cloning and expression of cDNA encoding the enzyme that controls conversion of high-mannose to hybrid and complex N-glycans: UDP-N-acetylglucosamine: alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I. Proc Natl Acad Sci U S A (1991) 1.19
Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide. Proc Natl Acad Sci U S A (1985) 1.19
Polyadenylation of the Xenopus beta 1 globin mRNA at a downstream minor site in the absence of the major site and utilization of an AAUACA polyadenylation signal. EMBO J (1985) 1.16
A multigene family of intron lacking and containing genes, encoding for mouse ribosomal protein L7. Nucleic Acids Res (1984) 1.08
Multiple polyadenylation sites in a Drosophila tropomyosin gene are used to generate functional mRNAs. Nucleic Acids Res (1985) 1.04
The suffix sequence is involved in processing the 3' ends of different mRNAs in Drosophila melanogaster. EMBO J (1986) 1.04
Human Cu/Zn superoxide dismutase gene: molecular characterization of its two mRNA species. Nucleic Acids Res (1984) 1.00
Barley alpha-amylase genes and the thiol protease gene Aleurain: use of a single poly(A) addition signal associated with a conserved pentanucleotide at the cleavage site. Proc Natl Acad Sci U S A (1989) 0.99
A complex repeated DNA sequence within the Drosophila transposable element copia. Nucleic Acids Res (1981) 0.98
Duplication of functional polyadenylation signals in polyomavirus DNA does not alter efficiency of polyadenylation or transcription termination. J Virol (1986) 0.98
Polyadenylation at a cryptic site in the pBR322 portion of pSV2-neo: prevention of its utilization by the SV40 late poly(A) signal. Nucleic Acids Res (1987) 0.96
Discrimination among multiple AATAAA sequences correlates with interspecies conservation of select 3' untranslated nucleotides. Nucleic Acids Res (1986) 0.94
Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene. Nucleic Acids Res (1987) 0.94
Human aldolase isozyme gene: the structure of multispecies aldolase B mRNAs. Nucleic Acids Res (1985) 0.92
Selection of sequence elements that substitute for the standard AATAAA motif which signals 3' processing and polyadenylation of late simian virus 40 mRNAs. Nucleic Acids Res (1985) 0.91
Structural characterization of a heterogeneous family of rat brain mRNAs. Mol Cell Biol (1986) 0.91
A genetic polymorphism within the third poly(A) signal of the DHFR gene alters the polyadenylation pattern of DHFR transcripts in CHL cells. Nucleic Acids Res (1994) 0.88
Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone. Proc Natl Acad Sci U S A (1986) 0.84
Multiple non-allelic genes encoding pancreatic alpha-amylase of mouse are expressed in a strain-specific fashion. EMBO J (1984) 0.80
Complete nucleotide sequence of mRNA for caerulein precursor from Xenopus skin: the mRNA contains an unusual repetitive structure. Nucleic Acids Res (1985) 0.79
Identification and expression profiles of IL-8 in bighead carp (Aristichthys nobilis) in response to microcystin-LR. Arch Environ Contam Toxicol (2013) 0.75
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes. Proc Natl Acad Sci U S A (1977) 40.24
3' non-coding region sequences in eukaryotic messenger RNA. Nature (1976) 39.12
A simple method for DNA restriction site mapping. Nucleic Acids Res (1976) 22.24
Methylmercury as a reversible denaturing agent for agarose gel electrophoresis. Anal Biochem (1976) 21.07
The ovalbumin gene-sequence of putative control regions. Nucleic Acids Res (1980) 18.04
Two mRNAs can be produced from a single immunoglobulin mu gene by alternative RNA processing pathways. Cell (1980) 9.86
Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase. Nature (1978) 8.76
Sequence of chicken ovalbumin mRNA. Nature (1978) 6.73
Steps in the processing of Ad2 mRNA: poly(A)+ nuclear sequences are conserved and poly(A) addition precedes splicing. Cell (1978) 6.36
The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA. Cell (1980) 5.80
Processing of RNA. Annu Rev Biochem (1976) 5.28
Tissue-specific expression of mouse-alpha-amylase genes: nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland. Cell (1980) 5.25
Tissue-specific expression of mouse alpha-amylase genes. J Mol Biol (1980) 4.30
Structure and genomic organization of the mouse dihydrofolate reductase gene. Cell (1980) 4.25
Size heterogeneity in the 3' end of dihydrofolate reductase messenger RNAs in mouse cells. Cell (1980) 4.23
Eukaryotic messenger RNA. Annu Rev Biochem (1974) 2.43
Structure of two adenovirus type 12 transforming polypeptides and their evolutionary implications. Nature (1980) 2.38
Transcription units of adenovirus type 2. Termination of transcription beyond the poly(A) addition site in early regions 2 and 4. J Mol Biol (1980) 2.11
The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site. J Mol Biol (1979) 2.04
Comparison of mRNA precursors in plasmacytomas producing closely related kappa chains. Proc Natl Acad Sci U S A (1979) 1.26
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
Genome-wide location and function of DNA binding proteins. Science (2000) 31.25
Dissecting the regulatory circuitry of a eukaryotic genome. Cell (1998) 23.62
Yeast RNA polymerase II genes: isolation with antibody probes. Science (1983) 17.91
A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell (1998) 10.92
Tissue-specific in vitro transcription from the mouse albumin promoter. Cell (1986) 10.54
Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell (2001) 9.63
Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells. Cell (1978) 8.98
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev (2000) 8.19
Serial regulation of transcriptional regulators in the yeast cell cycle. Cell (2001) 7.99
Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus. J Virol (1990) 7.90
A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell (1991) 7.64
Dissection of Mycobacterium tuberculosis antigens using recombinant DNA. Proc Natl Acad Sci U S A (1985) 7.46
Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science (2000) 6.55
Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae. Nature (1985) 6.54
Epitope tagging and protein surveillance. Methods Enzymol (1991) 6.47
An RNA polymerase II holoenzyme responsive to activators. Nature (1994) 6.22
The interplay of DNA-binding proteins on the promoter of the mouse albumin gene. Cell (1987) 6.14
Transcription of eukaryotic protein-coding genes. Annu Rev Genet (2000) 6.12
Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science (2001) 6.06
Stress proteins are immune targets in leprosy and tuberculosis. Proc Natl Acad Sci U S A (1988) 5.68
The plasticity of dendritic cell responses to pathogens and their components. Science (2001) 5.58
Efficient mapping of protein antigenic determinants. Proc Natl Acad Sci U S A (1986) 5.38
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell (1993) 5.35
Tissue-specific expression of mouse-alpha-amylase genes: nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland. Cell (1980) 5.25
Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver. Cell (1983) 5.22
A single mouse alpha-amylase gene specifies two different tissue-specific mRNAs. Cell (1981) 5.03
LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein. Genes Dev (1990) 4.98
A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature (1995) 4.93
The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells. Cell (1978) 4.92
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev (2001) 4.91
Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA. Proc Natl Acad Sci U S A (1978) 4.90
Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast. Nature (1999) 4.71
Tissue-specific expression of mouse alpha-amylase genes. J Mol Biol (1980) 4.30
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli. Cell (1980) 4.19
Sequence of the 16 S-23 s spacer region in two ribosomal RNA operons of Escherichia coli. J Biol Chem (1979) 4.19
Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell (1987) 4.15
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol Cell (1998) 4.09
RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell (1996) 4.03
Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks. Pac Symp Biocomput (2001) 3.97
Prokaryotic and eukaryotic RNA polymerases have homologous core subunits. Proc Natl Acad Sci U S A (1987) 3.80
Oxpentifylline treatment of venous ulcers of the leg. BMJ (1990) 3.75
Human T-cell clones recognize a major M. leprae protein antigen expressed in E. coli. Nature (1986) 3.51
DBP, a liver-enriched transcriptional activator, is expressed late in ontogeny and its tissue specificity is determined posttranscriptionally. Cell (1990) 3.44
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev (1998) 3.42
Tandem promoters direct E. coli ribosomal RNA synthesis. Cell (1979) 3.36
RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Mol Cell Biol (1989) 3.21
Redundant roles for the TFIID and SAGA complexes in global transcription. Nature (2000) 3.21
Lambda gt 11: gene isolation with antibody probes and other applications. Methods Enzymol (1987) 3.17
Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts. Curr Biol (2000) 3.12
Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics (1989) 3.04
CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Proc Natl Acad Sci U S A (1993) 2.98
Circadian transcription of the cholesterol 7 alpha hydroxylase gene may involve the liver-enriched bZIP protein DBP. Genes Dev (1993) 2.96
The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem Sci (1995) 2.96
Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res (2000) 2.91
General requirement for RNA polymerase II holoenzymes in vivo. Proc Natl Acad Sci U S A (1995) 2.88
The Fibres of Retiform Tissue. J Physiol (1892) 2.87
Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature (1995) 2.87
The role of cis-acting promoter elements in tissue-specific albumin gene expression. Science (1989) 2.86
CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. Genes Dev (2000) 2.84
Humoral and cell-mediated immune responses to live recombinant BCG-HIV vaccines. Nature (1991) 2.83
Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1. J Exp Med (1994) 2.81
Genes for the major protein antigens of Mycobacterium tuberculosis: the etiologic agents of tuberculosis and leprosy share an immunodominant antigen. Proc Natl Acad Sci U S A (1987) 2.79
Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro. J Biol Chem (1991) 2.76
Mouse liver and salivary gland alpha-amylase mRNAs differ only in 5' non-translated sequences. Nature (1981) 2.73
The etiologic agents of leprosy and tuberculosis share an immunoreactive protein antigen with the vaccine strain Mycobacterium bovis BCG. Infect Immun (1987) 2.66
The primary transcription product of a silkworm alanine tRNA gene: identification of in vitro sites of initiation, termination and processing. Cell (1979) 2.66
Gene replacement and expression of foreign DNA in mycobacteria. J Bacteriol (1990) 2.65
Association of an activator with an RNA polymerase II holoenzyme. Genes Dev (1995) 2.61
BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A (1997) 2.55
Transposition of the Escherichia coli insertion element gamma generates a five-base-pair repeat. Proc Natl Acad Sci U S A (1979) 2.47
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals. Nature (1990) 2.46
Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site. Cell (1984) 2.44
A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Cell (1995) 2.41
RNA polymerase II holoenzymes and subcomplexes. J Biol Chem (1998) 2.39
An activator target in the RNA polymerase II holoenzyme. Mol Cell (1998) 2.37
The ankle injury--indications for the selective use of X-rays. Injury (1983) 2.35
Physical isolation of nascent RNA chains transcribed by RNA polymerase II: evidence for cotranscriptional splicing. Mol Cell Biol (1994) 2.35
Characterization of antibody-reactive epitopes on the 65-kilodalton protein of Mycobacterium leprae. Infect Immun (1987) 2.30
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J (1996) 2.28
Glucocorticoid hormones inhibit food-induced phase-shifting of peripheral circadian oscillators. EMBO J (2001) 2.24
Selective suppression of the transcription of ribosomal genes in mouse-human hybrid cells. J Cell Physiol (1979) 2.21
Stress proteins may provide a link between the immune response to infection and autoimmunity. Int Immunol (1989) 2.21
Gene isolation by screening lambda gt11 libraries with antibodies. Methods Enzymol (1987) 2.20
Expression of the liver-enriched transcriptional activator protein DBP follows a stringent circadian rhythm. Cell (1990) 2.19
Human T cell clones recognize two abundant Mycobacterium tuberculosis protein antigens expressed in Escherichia coli. J Immunol (1987) 2.19
T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection. J Immunol (1997) 2.18
The DBP gene is expressed according to a circadian rhythm in the suprachiasmatic nucleus and influences circadian behavior. EMBO J (1997) 2.17
A mammalian SRB protein associated with an RNA polymerase II holoenzyme. Nature (1996) 2.16
An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae. Mol Cell (1999) 2.14
Regulation of gene expression by TBP-associated proteins. Genes Dev (1998) 2.12