Published in Cell on August 01, 1980
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
DNA sequence and genome organization of genital human papillomavirus type 6b. EMBO J (1983) 5.42
Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids. Mol Cell Biol (1983) 3.63
Structure of a human histone cDNA: evidence that basally expressed histone genes have intervening sequences and encode polyadenylylated mRNAs. Proc Natl Acad Sci U S A (1985) 3.51
Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene. J Virol (1987) 3.36
Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site. Mol Cell Biol (1984) 3.09
Nucleotide and deduced amino acid sequences of Torpedo californica acetylcholine receptor gamma subunit. Proc Natl Acad Sci U S A (1983) 3.01
Multiple polyadenylation sites in a mouse alpha-amylase gene. Nucleic Acids Res (1981) 2.96
Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA. Proc Natl Acad Sci U S A (1983) 2.84
Identification of peroxisomal targeting signals located at the carboxy terminus of four peroxisomal proteins. J Cell Biol (1988) 2.77
Characterization of four outer membrane proteins that play a role in utilization of starch by Bacteroides thetaiotaomicron. J Bacteriol (1997) 2.72
Skeletal muscle actin mRNA. Characterization of the 3' untranslated region. Nucleic Acids Res (1981) 2.67
The complete amino acid sequence of human complement factor H. Biochem J (1988) 2.63
Constitutively expressed rat mRNA encoding a 70-kilodalton heat-shock-like protein. Mol Cell Biol (1985) 2.51
Structure and expression of cloned murine IFN-alpha genes. Nucleic Acids Res (1983) 2.35
Unusual evolutionary conservation and frequent DNA segment exchange in class I genes of the major histocompatibility complex. Proc Natl Acad Sci U S A (1983) 2.21
The nucleotide sequence of the chicken thymidine kinase gene and the relationship of its predicted polypeptide to that of the vaccinia virus thymidine kinase. Nucleic Acids Res (1984) 1.96
Three dimensional structure of porcine pancreatic alpha-amylase at 2.9 A resolution. Role of calcium in structure and activity. EMBO J (1987) 1.87
Nucleotide sequence of the Bacillus stearothermophilus alpha-amylase gene. J Bacteriol (1985) 1.81
Differential regulation of trypsinogen mRNA translation: full-length mRNA sequences encoding two oppositely charged trypsinogen isoenzymes in the dog pancreas. Mol Cell Biol (1985) 1.70
Comparative analysis of the 5'-end regions of two repressible acid phosphatase genes in Saccharomyces cerevisiae. Mol Cell Biol (1983) 1.68
Structure and expression of mouse VL30 genes. Mol Cell Biol (1983) 1.62
Multiple 3' ends of the chicken pro alpha 2(I) collagen gene. Nucleic Acids Res (1983) 1.61
Analysis in Cos-1 cells of processing and polyadenylation signals by using derivatives of the herpes simplex virus type 1 thymidine kinase gene. Mol Cell Biol (1983) 1.58
Mouse beta-globin and adenovirus-2 major late transcripts are initiated at the cap site in vitro. Proc Natl Acad Sci U S A (1981) 1.57
The alpha-amylase gene in Drosophila melanogaster: nucleotide sequence, gene structure and expression motifs. Nucleic Acids Res (1986) 1.56
Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids. Mol Cell Biol (1986) 1.49
Detailed analysis of the mRNAs mapping in the short unique region of herpes simplex virus type 1. Nucleic Acids Res (1985) 1.48
Nucleotide sequence of the extracellular glucoamylase gene STA1 in the yeast Saccharomyces diastaticus. J Bacteriol (1985) 1.45
Rat prostatic steroid binding protein: DNA sequence and transcript maps of the two C3 genes. EMBO J (1983) 1.35
Tissue-specific and insulin-dependent expression of a pancreatic amylase gene in transgenic mice. Mol Cell Biol (1987) 1.35
Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism. Nucleic Acids Res (1985) 1.33
A 3' co-terminus of two early herpes simplex virus type 1 mRNAs. Nucleic Acids Res (1982) 1.33
Molecular cloning of alpha-amylase genes from Drosophila melanogaster. I. Clone isolation by use of a mouse probe. Genetics (1985) 1.32
Isolation and analysis of genomic DNA clones encoding the third component of mouse complement. Proc Natl Acad Sci U S A (1982) 1.30
Characterization of a mouse interferon gene locus I. Isolation of a cluster of four alpha interferon genes. Nucleic Acids Res (1985) 1.27
alpha-Amylase gene of Streptomyces limosus: nucleotide sequence, expression motifs, and amino acid sequence homology to mammalian and invertebrate alpha-amylases. J Bacteriol (1987) 1.27
Identification of cDNA clones encoding secretory isoenzyme forms: sequence determination of canine pancreatic prechymotrypsinogen 2 mRNA. Proc Natl Acad Sci U S A (1983) 1.25
Primary structure of the immunoglobulin J chain from the mouse. Proc Natl Acad Sci U S A (1982) 1.24
Nucleotide sequence of the constant region of a chicken mu heavy chain immunoglobulin mRNA. Nucleic Acids Res (1983) 1.22
Concerted evolution of human amylase genes. Mol Cell Biol (1988) 1.18
Polyadenylation of the Xenopus beta 1 globin mRNA at a downstream minor site in the absence of the major site and utilization of an AAUACA polyadenylation signal. EMBO J (1985) 1.16
Expression of tissue-specific Ren-1 and Ren-2 genes of mice: comparative analysis of 5'-proximal flanking regions. Mol Cell Biol (1984) 1.16
The ovalbumin gene family: complete sequence and structure of the Y gene. Nucleic Acids Res (1982) 1.16
Cloned cDNA to cholecystokinin mRNA predicts an identical preprocholecystokinin in pig brain and gut. Proc Natl Acad Sci U S A (1984) 1.12
Sequence of rat alpha- and gamma-casein mRNAs: evolutionary comparison of the calcium-dependent rat casein multigene family. Nucleic Acids Res (1982) 1.10
Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res (1986) 1.09
Preparation of a "functional library" of African green monkey DNA fragments which substitute for the processing/polyadenylation signal in the herpes simplex virus type 1 thymidine kinase gene. Mol Cell Biol (1983) 1.07
A single element of the elastase I enhancer is sufficient to direct transcription selectively to the pancreas and gut. Mol Cell Biol (1994) 1.07
The DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse development. Mol Cell Biol (1990) 1.06
Multiple polyadenylation sites in a Drosophila tropomyosin gene are used to generate functional mRNAs. Nucleic Acids Res (1985) 1.04
Tissue specific and non-specific changes in gene expression by aging and by early stage CR. Mech Ageing Dev (2006) 1.04
Selective amplification of polymorphic dihydrofolate reductase gene loci in Chinese hamster lung cells. Proc Natl Acad Sci U S A (1982) 1.03
Molecular cloning of mouse PSP mRNA. Nucleic Acids Res (1985) 1.03
Heterogeneous initiation regions for transcription of the chicken ovomucoid gene. Nucleic Acids Res (1982) 1.03
The nucleotide sequence of the very low density lipoprotein II mRNA from chicken. Nucleic Acids Res (1981) 0.99
Reverse transcription of avian myeloblastosis virus 35S RNA. Early synthesis of plus strand DNA of discrete size in reconstructed reactions. Nucleic Acids Res (1982) 0.99
Primary sequence domains required for the retention of rotavirus VP7 in the endoplasmic reticulum. J Cell Biol (1988) 0.98
Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA. Proc Natl Acad Sci U S A (1986) 0.96
Characterization of ribosome binding on Rous sarcoma virus RNA in vitro. J Virol (1985) 0.94
A 78-kilobase region of mouse chromosome 3 contains salivary and pancreatic amylase genes and a pseudogene. Proc Natl Acad Sci U S A (1985) 0.94
Abundant androgen regulated mRNAs in mouse submandibular gland: cell-free translation of renin precursor mRNA. Nucleic Acids Res (1981) 0.93
Human aldolase isozyme gene: the structure of multispecies aldolase B mRNAs. Nucleic Acids Res (1985) 0.92
Selection of sequence elements that substitute for the standard AATAAA motif which signals 3' processing and polyadenylation of late simian virus 40 mRNAs. Nucleic Acids Res (1985) 0.91
Two distinct pancreatic amylase genes are active in YBR mice. Genetics (1982) 0.91
Structure of amylase genes in populations of Pacific Cupped oyster ( Crassostrea gigas): tissue expression and allelic polymorphism. Mar Biotechnol (NY) (2004) 0.90
An experimental model of autoimmune pancreatitis in the rat. Am J Pathol (2005) 0.88
Close physical linkage of the murine Ren-1 and Ren-2 loci. Nucleic Acids Res (1988) 0.88
Simultaneous expression of salivary and pancreatic amylase genes in cultured mouse hepatoma cells. Mol Cell Biol (1986) 0.85
Variation in amylase haplotypes among congenic lines of the house mouse. Genetics (1982) 0.84
Interstrain variation in amylase gene copy number and mRNA abundance in three mouse tissues. Genetics (1986) 0.83
Physical characterization of genetic rearrangements at the mouse renin loci. Genetics (1990) 0.81
Structural and functional analysis of an alternatively spliced chicken TK messenger RNA. Nucleic Acids Res (1986) 0.80
Multiple non-allelic genes encoding pancreatic alpha-amylase of mouse are expressed in a strain-specific fashion. EMBO J (1984) 0.80
Nucleotide sequence upstream of a glucose-repressible Drosophila gene. Nucleic Acids Res (1987) 0.80
Glucocorticoid and developmental regulation of amylase mRNAs in mouse liver cells. Mol Cell Biol (1988) 0.80
Effect of C-domain N-glycosylation and deletion on rat pancreatic alpha-amylase secretion and activity. Biochem J (2002) 0.79
A novel yeast secretion signal isolated from 28K killer precursor protein encoded on the linear DNA plasmid pGKL1. Nucleic Acids Res (1988) 0.79
Purification and characterization of alpha-amylase from rat pancreatic acinar carcinoma. Comparison with pancreatic alpha-amylase. Biochem J (1987) 0.77
Expression and Localization of α-amylase in the Submandibular and Sublingual Glands of Mice. Acta Histochem Cytochem (2014) 0.76
A BamHI RFLP at the Pim-1 locus on mouse chromosome 17. Nucleic Acids Res (1987) 0.75
Proteomic analysis of pancreas in miniature pigs according to developmental stages using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Lab Anim Res (2014) 0.75
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
Genome-wide location and function of DNA binding proteins. Science (2000) 31.25
Dissecting the regulatory circuitry of a eukaryotic genome. Cell (1998) 23.62
Yeast RNA polymerase II genes: isolation with antibody probes. Science (1983) 17.91
Remodeling of yeast genome expression in response to environmental changes. Mol Biol Cell (2001) 9.63
Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells. Cell (1978) 8.98
Serial regulation of transcriptional regulators in the yeast cell cycle. Cell (2001) 7.99
Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus. J Virol (1990) 7.90
Dissection of Mycobacterium tuberculosis antigens using recombinant DNA. Proc Natl Acad Sci U S A (1985) 7.46
Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae. Nature (1985) 6.54
Epitope tagging and protein surveillance. Methods Enzymol (1991) 6.47
An RNA polymerase II holoenzyme responsive to activators. Nature (1994) 6.22
Transcription of eukaryotic protein-coding genes. Annu Rev Genet (2000) 6.12
Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science (2001) 6.06
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc Natl Acad Sci U S A (1992) 5.94
Stress proteins are immune targets in leprosy and tuberculosis. Proc Natl Acad Sci U S A (1988) 5.68
The plasticity of dendritic cell responses to pathogens and their components. Science (2001) 5.58
Efficient mapping of protein antigenic determinants. Proc Natl Acad Sci U S A (1986) 5.38
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell (1993) 5.35
Two promoters of different strengths control the transcription of the mouse alpha-amylase gene Amy-1a in the parotid gland and the liver. Cell (1983) 5.22
A single mouse alpha-amylase gene specifies two different tissue-specific mRNAs. Cell (1981) 5.03
A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature (1995) 4.93
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev (2001) 4.91
Complementary sequences 1700 nucleotides apart form a ribonuclease III cleavage site in Escherichia coli ribosomal precursor RNA. Proc Natl Acad Sci U S A (1978) 4.90
Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast. Nature (1999) 4.71
The ribonuclease III site flanking 23S sequences in the 30S ribosomal precursor RNA of E. coli. Cell (1980) 4.19
Sequence of the 16 S-23 s spacer region in two ribosomal RNA operons of Escherichia coli. J Biol Chem (1979) 4.19
Functional redundancy and structural polymorphism in the large subunit of RNA polymerase II. Cell (1987) 4.15
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol Cell (1998) 4.09
RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell (1996) 4.03
Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks. Pac Symp Biocomput (2001) 3.97
Prokaryotic and eukaryotic RNA polymerases have homologous core subunits. Proc Natl Acad Sci U S A (1987) 3.80
Oxpentifylline treatment of venous ulcers of the leg. BMJ (1990) 3.75
Human T-cell clones recognize a major M. leprae protein antigen expressed in E. coli. Nature (1986) 3.51
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev (1998) 3.42
Tandem promoters direct E. coli ribosomal RNA synthesis. Cell (1979) 3.36
RNA polymerase II subunit RPB4 is essential for high- and low-temperature yeast cell growth. Mol Cell Biol (1989) 3.21
Redundant roles for the TFIID and SAGA complexes in global transcription. Nature (2000) 3.21
Lambda gt 11: gene isolation with antibody probes and other applications. Methods Enzymol (1987) 3.17
Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics (1989) 3.04
Multiple polyadenylation sites in a mouse alpha-amylase gene. Nucleic Acids Res (1981) 2.96
The RNA polymerase II holoenzyme and its implications for gene regulation. Trends Biochem Sci (1995) 2.96
Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res (2000) 2.91
General requirement for RNA polymerase II holoenzymes in vivo. Proc Natl Acad Sci U S A (1995) 2.88
The Fibres of Retiform Tissue. J Physiol (1892) 2.87
Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature (1995) 2.87
Humoral and cell-mediated immune responses to live recombinant BCG-HIV vaccines. Nature (1991) 2.83
Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1. J Exp Med (1994) 2.81
Genes for the major protein antigens of Mycobacterium tuberculosis: the etiologic agents of tuberculosis and leprosy share an immunodominant antigen. Proc Natl Acad Sci U S A (1987) 2.79
Two dissociable subunits of yeast RNA polymerase II stimulate the initiation of transcription at a promoter in vitro. J Biol Chem (1991) 2.76
Mouse liver and salivary gland alpha-amylase mRNAs differ only in 5' non-translated sequences. Nature (1981) 2.73
The etiologic agents of leprosy and tuberculosis share an immunoreactive protein antigen with the vaccine strain Mycobacterium bovis BCG. Infect Immun (1987) 2.66
The primary transcription product of a silkworm alanine tRNA gene: identification of in vitro sites of initiation, termination and processing. Cell (1979) 2.66
Gene replacement and expression of foreign DNA in mycobacteria. J Bacteriol (1990) 2.65
Association of an activator with an RNA polymerase II holoenzyme. Genes Dev (1995) 2.61
BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A (1997) 2.55
Transposition of the Escherichia coli insertion element gamma generates a five-base-pair repeat. Proc Natl Acad Sci U S A (1979) 2.47
RNA polymerase II C-terminal repeat influences response to transcriptional enhancer signals. Nature (1990) 2.46
Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site. Cell (1984) 2.44
RNA polymerase II holoenzymes and subcomplexes. J Biol Chem (1998) 2.39
An activator target in the RNA polymerase II holoenzyme. Mol Cell (1998) 2.37
The ankle injury--indications for the selective use of X-rays. Injury (1983) 2.35
Characterization of antibody-reactive epitopes on the 65-kilodalton protein of Mycobacterium leprae. Infect Immun (1987) 2.30
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J (1996) 2.28
Stress proteins may provide a link between the immune response to infection and autoimmunity. Int Immunol (1989) 2.21
Gene isolation by screening lambda gt11 libraries with antibodies. Methods Enzymol (1987) 2.20
Human T cell clones recognize two abundant Mycobacterium tuberculosis protein antigens expressed in Escherichia coli. J Immunol (1987) 2.19
T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection. J Immunol (1997) 2.18
A mammalian SRB protein associated with an RNA polymerase II holoenzyme. Nature (1996) 2.16
An unusual eukaryotic protein phosphatase required for transcription by RNA polymerase II and CTD dephosphorylation in S. cerevisiae. Mol Cell (1999) 2.14
Regulation of gene expression by TBP-associated proteins. Genes Dev (1998) 2.12
Mapping of T cell epitopes using recombinant antigens and synthetic peptides. EMBO J (1987) 2.09
Subunits shared by eukaryotic nuclear RNA polymerases. Genes Dev (1990) 2.09
The yeast A kinases differentially regulate iron uptake and respiratory function. Proc Natl Acad Sci U S A (2000) 1.98
A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell (1992) 1.98
The mouse alpha-amylase multigene family. Sequence organization of members expressed in the pancreas, salivary gland and liver. J Mol Biol (1982) 1.96
Increased antimycobacterial immunity in interleukin-10-deficient mice. Infect Immun (1999) 1.95
T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein. J Immunol (1989) 1.94
Conditional mutations occur predominantly in highly conserved residues of RNA polymerase II subunits. Mol Cell Biol (1990) 1.92
Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution. J Mol Biol (1975) 1.90
The nucleotide sequence of two silk gland alanine tRNAs: implications for fibroin synthesis and for initiator tRNA structure. Cell (1977) 1.86
RNA polymerase II subunit composition, stoichiometry, and phosphorylation. Mol Cell Biol (1990) 1.85
A portion of RNA polymerase II molecules has a component essential for stress responses and stress survival. Mol Cell Biol (1993) 1.83
RNA polymerase II subunit RPB3 is an essential component of the mRNA transcription apparatus. Mol Cell Biol (1989) 1.81
Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas. Mol Cell Biol (1989) 1.80
The uraA locus and homologous recombination in Mycobacterium bovis BCG. J Bacteriol (1993) 1.75
Regulation of specific DNA binding by p53: evidence for a role for O-glycosylation and charged residues at the carboxy-terminus. Oncogene (1996) 1.75
Screening of a recombinant mycobacterial DNA library with polyclonal antiserum and molecular weight analysis of expressed antigens. Infect Immun (1987) 1.74
RPB7, one of two dissociable subunits of yeast RNA polymerase II, is essential for cell viability. Yeast (1993) 1.71
Transcription termination in the Escherichia coli ribosomal RNA operon rrnC. J Biol Chem (1979) 1.70
Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme. Mol Cell Biol (1998) 1.69
Yeast RNA polymerase II subunit RPB9 is essential for growth at temperature extremes. J Biol Chem (1991) 1.67
A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis. Proc Natl Acad Sci U S A (1997) 1.67
Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin. Infect Immun (1999) 1.65
In vivo and in vitro characterization of murine T-cell clones reactive to Mycobacterium tuberculosis. Infect Immun (1987) 1.63