Published in Cell on August 01, 1983
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol (2000) 5.28
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol Cell Biol (2002) 2.66
Coding sequence and growth regulation of the human vimentin gene. Mol Cell Biol (1986) 2.34
Keratins as markers that distinguish normal and tumor-derived mammary epithelial cells. Proc Natl Acad Sci U S A (1990) 1.81
Asbestos-associated chromosomal changes in human mesothelial cells. Proc Natl Acad Sci U S A (1985) 1.60
Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling. Am J Pathol (2005) 1.60
Differential control of cytokeratins and vimentin synthesis by cell-cell contact and cell spreading in cultured epithelial cells. J Cell Biol (1984) 1.57
Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney. Am J Pathol (1987) 1.53
Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma. Am J Pathol (1989) 1.51
Cloning of the human keratin 18 gene and its expression in nonepithelial mouse cells. Mol Cell Biol (1988) 1.43
Vimentin is preferentially expressed in human breast carcinomas with low estrogen receptor and high Ki-67 growth fraction. Am J Pathol (1990) 1.40
Suprabasal 40 kd keratin (K19) expression as an immunohistologic marker of premalignancy in oral epithelium. Am J Pathol (1989) 1.36
Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment. Proc Natl Acad Sci U S A (1992) 1.34
Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro. Am J Physiol Lung Cell Mol Physiol (2009) 1.27
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The gene encoding human vimentin is located on the short arm of chromosome 10. Am J Hum Genet (1987) 1.17
Evaluation of an attenuated vesicular stomatitis virus vector expressing interferon-beta for use in malignant pleural mesothelioma: heterogeneity in interferon responsiveness defines potential efficacy. Hum Gene Ther (2010) 1.14
The anti-adhesive mucin podocalyxin may help initiate the transperitoneal metastasis of high grade serous ovarian carcinoma. Clin Exp Metastasis (2012) 1.13
Villin--a marker of brush border differentiation and cellular origin in human renal cell carcinoma. Am J Pathol (1986) 1.11
Co-expression of cytokeratins and neurofilament proteins in a permanent cell line: cultured rat PC12 cells combine neuronal and epithelial features. J Cell Biol (1986) 1.08
Mesosecrin: a secreted glycoprotein produced in abundance by human mesothelial, endothelial, and kidney epithelial cells in culture. J Cell Biol (1987) 1.08
Evidence of a role for mesothelial cell-derived interleukin 8 in the pathogenesis of asbestos-induced pleurisy in rabbits. J Clin Invest (1992) 1.07
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells. Biochem J (1992) 1.06
Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations. Am J Pathol (1994) 1.06
Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells. J Cell Biol (1988) 1.05
The intermediate filament cytoskeleton of malignant mesotheliomas and its diagnostic significance. Am J Pathol (1985) 1.01
Regulation of the terminal event in cellular differentiation: biological mechanisms of the loss of proliferative potential. J Cell Biol (1986) 1.00
Regulation of human mesothelial cell differentiation: opposing roles of retinoids and epidermal growth factor in the expression of intermediate filament proteins. J Cell Biol (1987) 0.98
Metalloproteinases and tissue inhibitor of metalloproteinases in mesothelial cells. Cellular differentiation influences expression. J Clin Invest (1993) 0.97
GAS5 long non-coding RNA in malignant pleural mesothelioma. Mol Cancer (2014) 0.97
Anaplastic carcinoma associated with a mucinous cystic neoplasm of the pancreas during pregnancy: report of a case and a review of the literature. World J Gastroenterol (2008) 0.96
An unusual strain of human keratinocytes which do not stratify or undergo terminal differentiation in culture. J Cell Biol (1988) 0.93
Sequence and expression of a human type II mesothelial keratin. J Cell Biol (1985) 0.92
Changes in expression of differentiation markers between normal ovarian cells and derived tumors. Am J Pathol (1993) 0.92
To grow mouse mammary epithelial cells in culture. J Cell Biol (1984) 0.92
Transgenic expression of the muscle-specific intermediate filament protein desmin in nonmuscle cells. J Cell Biol (1989) 0.91
Polarized secretion of interleukin-8 by human mesothelial cells: a role in neutrophil migration. Immunology (1995) 0.90
Chordomas with malignant spindle cell components. A DNA flow cytometric and immunohistochemical study with histogenetic implications. Am J Pathol (1990) 0.89
Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers. Dig Dis Sci (2007) 0.89
Mesothelial cells stimulate the anchorage-independent growth of human ovarian tumour cells. Br J Cancer (1989) 0.85
Phenotypic change and accumulation of smooth muscle cells in strictures in Crohn's disease: relevance to local angiotensin II system. J Gastroenterol (2010) 0.84
Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes. J Clin Invest (1990) 0.83
Chlamydia trachomatis infection of human mesothelial cells alters proinflammatory, procoagulant, and fibrinolytic responses. Infect Immun (1998) 0.82
Inhibition of vimentin synthesis and disruption of intermediate filaments in simian virus 40-infected monkey kidney cells. Mol Cell Biol (1984) 0.82
Routes of Ca2+ Shuttling during Ca2+ Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca2+ HANDLING AND CYTOSOLIC Ca2+ BUFFERS. J Biol Chem (2015) 0.79
Bacterial induction of early response genes and activation of proapoptotic factors in pleural mesothelial cells. Lung (2007) 0.79
Establishment of immortalized murine mesothelial cells and a novel mesothelioma cell line. In Vitro Cell Dev Biol Anim (2015) 0.79
Normal and SV40 transfected human peritoneal mesothelial cells produce IL-6 and IL-8: implication for gynaecological disease. Clin Exp Immunol (2002) 0.78
AMA1-deficient Toxoplasma gondii parasites transiently colonize mice and trigger an innate immune response that leads to long-lasting protective immunity. Infect Immun (2015) 0.77
Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum. PLoS One (2016) 0.76
Establishment and characterisation of two cell lines derived from a primary adenocarcinoma of the duodenum. Clin Mol Pathol (1996) 0.75
Overexpression or absence of calretinin in mouse primary mesothelial cells inversely affects proliferation and cell migration. Respir Res (2015) 0.75
In vitro experimental models of mesothelioma revisited. Transl Lung Cancer Res (2017) 0.75
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell (1975) 15.93
Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proc Natl Acad Sci U S A (1997) 15.25
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol (2000) 5.28
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas. Cancer Res (1981) 5.08
Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes. Nature (1977) 4.90
A transmissible plasmid controlling camphor oxidation in Pseudomonas putida. Proc Natl Acad Sci U S A (1973) 4.57
The mesothelial keratins: a new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia. Cell (1982) 4.17
Characterization of the phylogenetic distribution and chromosomal insertion sites of five IS6110 elements in Mycobacterium tuberculosis: non-random integration in the dnaA-dnaN region. Tuber Lung Dis (1998) 3.15
A new small (40 kd) keratin filament protein made by some cultured human squamous cell carcinomas. Cell (1981) 2.87
Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteins. Biol Reprod (1997) 2.74
Hyaluronic acid capsule and the role of streptococcal entry into keratinocytes in invasive skin infection. J Clin Invest (1996) 2.57
Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell (1980) 2.39
Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma. Cell (1975) 2.06
Tissue specificity of epithelial keratins: differential expression of mRNAs from two multigene families. Mol Cell Biol (1983) 1.75
Polycyclic aromatic hydrocarbon mutagenesis of human epidermal keratinocytes in culture. Proc Natl Acad Sci U S A (1984) 1.74
Serial cultivation of normal human epidermal keratinocytes. Methods Cell Biol (1980) 1.71
Intraperitoneal injection of genetically modified, human mesothelial cells for systemic gene therapy. Hum Gene Ther (1997) 1.49
In vitro propagation of human ocular surface epithelial cells for transplantation. Invest Ophthalmol Vis Sci (1993) 1.37
Suprabasal 40 kd keratin (K19) expression as an immunohistologic marker of premalignancy in oral epithelium. Am J Pathol (1989) 1.36
Abnormal expression of retinoic acid receptors and keratin 19 by human oral and epidermal squamous cell carcinoma cell lines. Cancer Res (1991) 1.32
Failure of hydrocortisone or growth factors to influence the senescence of fibroblasts in a new culture system for assessing replicative lifespan. J Cell Physiol (1981) 1.19
Three distinct keratinocyte subtypes identified in human oral epithelium by their patterns of keratin expression in culture and in xenografts. Differentiation (1990) 1.16
Coexpression of simple epithelial keratins and vimentin by human mesothelium and mesothelioma in vivo and in culture. Cancer Res (1984) 1.15
Properties of an epithelial cell type in culture: the epidermal keratinocyte and its dependence on products of the fibroblast. Prog Clin Biol Res (1977) 1.14
Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Blood (1989) 1.12
A peptide permease mutant of Mycobacterium bovis BCG resistant to the toxic peptides glutathione and S-nitrosoglutathione. Infect Immun (2000) 1.11
Mesosecrin: a secreted glycoprotein produced in abundance by human mesothelial, endothelial, and kidney epithelial cells in culture. J Cell Biol (1987) 1.08
Human sweat gland myoepithelial cells express a unique set of cytokeratins and reveal the potential for alternative epithelial and mesenchymal differentiation states in culture. J Cell Sci (1999) 1.04
A limited role for retinoic acid and retinoic acid receptors RAR alpha and RAR beta in regulating keratin 19 expression and keratinization in oral and epidermal keratinocytes. J Invest Dermatol (1996) 1.02
Cellular X-ray repair parameters of early passage squamous cell carcinoma lines derived from patients with known responses to radiotherapy. Br J Cancer (1984) 1.00
Environment-dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor-beta. J Cell Physiol (1989) 0.98
Variable expression of retinoic acid receptor (RAR beta) mRNA in human oral and epidermal keratinocytes; relation to keratin 19 expression and keratinization potential. Differentiation (1991) 0.98
Effects of Mycobacterium bovis BCG infection on regulation of L-arginine uptake and synthesis of reactive nitrogen intermediates in J774.1 murine macrophages. Infect Immun (2001) 0.98
A monoclonal antibody recognizing a keratin filament protein in a subset of transitional and glandular epithelia. Differentiation (1984) 0.97
Interruption of the phosphoglucose isomerase gene results in glucose auxotrophy in Mycobacterium smegmatis. J Bacteriol (1997) 0.97
Normal human mesothelial cells and fibroblasts transfected with the EJras oncogene become EGF-independent, but are not malignantly transformed. Oncogene Res (1988) 0.95
Amino acid transport and metabolism in mycobacteria: cloning, interruption, and characterization of an L-Arginine/gamma-aminobutyric acid permease in Mycobacterium bovis BCG. J Bacteriol (2000) 0.93
Novel p53 splice site mutations in three families with Li-Fraumeni syndrome. Oncogene (2000) 0.92
Intermediate filament proteins as distinguishing markers of cell type and differentiated state in cultured human urinary tract epithelia. Ann N Y Acad Sci (1985) 0.90
Anchorage-independent growth of normal human mesothelial cells: a sensitive bioassay for EGF which discloses the absence of this factor in fetal calf serum. In Vitro Cell Dev Biol (1985) 0.87
Specific effects of ras oncogene expression on the growth and histogenesis of human epidermal keratinocytes. Oncogene (1990) 0.85
The role of terminal differentiation in the finite culture lifetime of the human epidermal keratinocyte. Int Rev Cytol Suppl (1979) 0.83
Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes. J Clin Invest (1990) 0.83
Cloned cDNA sequence for the human mesothelial protein 'mesosecrin' discloses its identity as a plasminogen activator inhibitor (PAI-1) and a recent evolutionary change in transcript processing. J Cell Sci (1989) 0.83
Characterization of a Mycobacterium smegmatis mutant that is simultaneously resistant to D-cycloserine and vancomycin. Antimicrob Agents Chemother (2000) 0.82
A mutant of Mycobacterium smegmatis defective in dipeptide transport. J Bacteriol (1998) 0.81
Growth of cultured mammalian cells on secondary glucose sources. Cell (1974) 0.81
6-deoxy-D-glucose and D-xylose: analogs for the study of D-glucose transport by mouse 3T3 cells. J Cell Physiol (1982) 0.79
Human squamous cell carcinoma in culture: a defect in terminal differentiation and its relation to malignancy. Natl Cancer Inst Monogr (1982) 0.78
Recombinant BCG as a candidate oral vaccine vector. Res Microbiol (1991) 0.78
Effect of glucose uptake on growth rate of mouse 3T3 cells. J Cell Physiol (1982) 0.75
Transport of 6-deoxy-D-glucose and D-xylose by untransformed and SV40-transformed 3T3 cells. J Cell Physiol (1982) 0.75
D-glucose transport by membrane vesicles from quiescent, serum-stimulated, and SV40-transformed mouse 3T3 cells. Biochim Biophys Acta (1983) 0.75