Published in Mol Immunol on February 01, 1982
T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins. Proc Natl Acad Sci U S A (1991) 2.32
Fc epsilon RI-mediated association of 6-micron beads with RBL-2H3 mast cells results in exclusion of signaling proteins from the forming phagosome and abrogation of normal downstream signaling. J Cell Biol (1996) 1.60
Aggregation of the high-affinity IgE receptor and enhanced activity of p53/56lyn protein-tyrosine kinase. Proc Natl Acad Sci U S A (1994) 1.47
Depolarization of rat basophilic leukemia cells inhibits calcium uptake and exocytosis. J Cell Biol (1987) 1.44
Crosslinking of the receptors for immunoglobulin E depolarizes the plasma membrane of rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1983) 1.41
Clustering, mobility, and triggering activity of small oligomers of immunoglobulin E on rat basophilic leukemia cells. J Cell Biol (1986) 1.40
Identification of the low affinity receptor for immunoglobulin E on mouse mast cells and macrophages as Fc gamma RII and Fc gamma RIII. J Exp Med (1992) 1.40
Small oligomers of immunoglobulin E (IgE) cause large-scale clustering of IgE receptors on the surface of rat basophilic leukemia cells. J Cell Biol (1984) 1.35
Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E. Proc Natl Acad Sci U S A (1988) 1.32
Identification of an IgE-binding protein by molecular cloning. Proc Natl Acad Sci U S A (1985) 1.13
The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH(2)-terminal kinase 1. J Exp Med (2000) 1.11
Dynamics of signal transduction after aggregation of cell-surface receptors: studies on the type I receptor for IgE. Proc Natl Acad Sci U S A (1994) 1.09
Modeling multivalent ligand-receptor interactions with steric constraints on configurations of cell-surface receptor aggregates. Biophys J (2010) 1.09
Early expression of high-affinity receptor for immunoglobulin E (Fc epsilon RI) during differentiation of mouse mast cells and human basophils. J Clin Invest (1990) 1.03
Interaction of aggregated native and mutant IgE receptors with the cellular skeleton. Proc Natl Acad Sci U S A (1992) 1.03
Unexpected signals in a system subject to kinetic proofreading. Proc Natl Acad Sci U S A (2001) 1.03
Transmembrane signaling by the high-affinity IgE receptor on membrane preparations. Proc Natl Acad Sci U S A (1992) 1.02
Quantifying aggregation of IgE-FcepsilonRI by multivalent antigen. Biophys J (1999) 0.93
Shuttling of initiating kinase between discrete aggregates of the high affinity receptor for IgE regulates the cellular response. Proc Natl Acad Sci U S A (1997) 0.90
Isoprenoid pathway activity is required for IgE receptor-mediated, tyrosine kinase-coupled transmembrane signaling in permeabilized RBL-2H3 rat basophilic leukemia cells. Cell Regul (1991) 0.89
Characterization of the ion channel activity in planar bilayers containing IgE-Fc epsilon receptor and the cromolyn-binding protein. EMBO J (1986) 0.80
Comparative evaluation of the effect of pharmacological agents on endocytosis and coendocytosis of IgE by rat basophilic leukaemia cells. Immunology (1986) 0.78
Membrane-bound IgE receptor complexes fused with rat basophilic leukemia cells mediate degranulation. J Cell Biol (1987) 0.75
Affinity labeling of a phosphorylcholine binding mouse myeloma protein. Biochemistry (1972) 4.26
Characterization of a human macroglobulin. II. Distribution of the disulfide bonds. J Biol Chem (1965) 3.64
The receptor with high affinity for immunoglobulin E. Annu Rev Immunol (1986) 3.53
Structural basis of antibody function. Annu Rev Immunol (1983) 3.41
The interaction of IgE with rat basophilic leukemia cells. II. Quantitative aspects of the binding reaction. J Exp Med (1974) 3.33
Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate. Science (1988) 3.07
Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation. Proc Natl Acad Sci U S A (1977) 3.07
Complete structure and expression in transfected cells of high affinity IgE receptor. Nature (1989) 2.97
Affinity labeling of a mouse myeloma protein which binds nitrophenyl ligands. Kinetics of labeling and isolation of a labeled peptide. Biochemistry (1970) 2.88
Compartmentalized activation of the high affinity immunoglobulin E receptor within membrane domains. J Biol Chem (1997) 2.83
Interaction between proteins localized in membranes. Proc Natl Acad Sci U S A (1986) 2.74
Quantitative analysis of phospholipids in functionally important membrane domains from RBL-2H3 mast cells using tandem high-resolution mass spectrometry. Biochemistry (1999) 2.71
Lateral motion and valence of Fc receptors on rat peritoneal mast cells. Nature (1976) 2.69
The influence of polyvalency on the binding properties of antibodies. Immunochemistry (1972) 2.67
Crosslinking a lipid raft component triggers liquid ordered-liquid disordered phase separation in model plasma membranes. Proc Natl Acad Sci U S A (2005) 2.60
Molecular crowding on the cell surface. Science (1988) 2.47
Critical role for cholesterol in Lyn-mediated tyrosine phosphorylation of FcepsilonRI and their association with detergent-resistant membranes. J Cell Biol (1999) 2.30
The interaction of IgE with rat basophilic leukemia cells. I. Evidence for specific binding of IgE. J Exp Med (1974) 2.30
Assessment of compositional relatedness between proteins. Nature (1968) 2.30
Fc epsilon RI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling. Proc Natl Acad Sci U S A (1995) 2.30
Characterization of gene expression in resting and activated mast cells. J Exp Med (1998) 2.24
Large-scale co-aggregation of fluorescent lipid probes with cell surface proteins. J Cell Biol (1994) 2.11
Structural studies on the membrane-bound immunoglobulin E-receptor complex. 1. Characterization of large plasma membrane vesicles from rat basophilic leukemia cells and insertion of amphipathic fluorescent probes. Biochemistry (1983) 2.08
Signal transduction by Fc receptors: the Fc epsilon RI case. Immunol Today (1993) 2.04
Larger oligomers of IgE are more effective than dimers in stimulating rat basophilic leukemia cells. J Immunol (1980) 1.92
Membrane organization in immunoglobulin E receptor signaling. Curr Opin Chem Biol (1999) 1.85
A cDNA presumptively coding for the alpha subunit of the receptor with high affinity for immunoglobulin E. Biochemistry (1987) 1.81
Distribution and valency of receptor for IgE on rodent mast cells and related tumour cells. Nature (1976) 1.78
Fluorescence anisotropy measurements of lipid order in plasma membranes and lipid rafts from RBL-2H3 mast cells. Biochemistry (2001) 1.75
Structure and function of gamma M macroglobulins. Adv Immunol (1970) 1.73
Characterization of a human macroglobulin. 3. The products of tryptic digestion. J Biol Chem (1966) 1.72
An unusual mechanism for ligand antagonism. Science (1998) 1.69
The IgE-mast cell system as a paradigm for the study of antibody mechanisms. Immunol Rev (1978) 1.68
Cross-linking of IgE-receptor complexes at the cell surface: a fluorescence method for studying the binding of monovalent and bivalent haptens to IgE. Mol Immunol (1986) 1.65
The effect of receptor density on the forward rate constant for binding of ligands to cell surface receptors. Biophys J (1987) 1.65
Medical problems of civil disorders. Organization of a volunteer group of health professionals to provide medical services in a riot. N Engl J Med (1969) 1.63
Cross-linking of receptor-bound IgE to aggregates larger than dimers leads to rapid immobilization. J Cell Biol (1986) 1.61
Fc epsilon RI-mediated association of 6-micron beads with RBL-2H3 mast cells results in exclusion of signaling proteins from the forming phagosome and abrogation of normal downstream signaling. J Cell Biol (1996) 1.60
Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation. Proc Natl Acad Sci U S A (1994) 1.58
Characterization of a human macroglobulin. V. A Waldenström macroglobulin with antibody activity. Proc Natl Acad Sci U S A (1967) 1.56
Electron spin resonance characterization of liquid ordered phase of detergent-resistant membranes from RBL-2H3 cells. Biophys J (1999) 1.55
Effect of antigen binding on the properties of antibody. Adv Immunol (1974) 1.55
Surface IgE on human basophils during histamine release. J Exp Med (1973) 1.48
Competition between solution and cell surface receptors for ligand. Dissociation of hapten bound to surface antibody in the presence of solution antibody. Biophys J (1989) 1.47
Aggregation of the high-affinity IgE receptor and enhanced activity of p53/56lyn protein-tyrosine kinase. Proc Natl Acad Sci U S A (1994) 1.47
Cross-correlation analysis of inner-leaflet-anchored green fluorescent protein co-redistributed with IgE receptors and outer leaflet lipid raft components. Biophys J (2001) 1.41
Crosslinking of the receptors for immunoglobulin E depolarizes the plasma membrane of rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1983) 1.41
Triggering of cultured neoplastic mast cells by antibodies to the receptor for IgE. J Immunol (1978) 1.40
Clustering, mobility, and triggering activity of small oligomers of immunoglobulin E on rat basophilic leukemia cells. J Cell Biol (1986) 1.40
The positive inotropic-acting forskolin, a potent adenylate cyclase activator. Arzneimittelforschung (1981) 1.40
Expression of high-affinity binding of human immunoglobulin E by transfected cells. Science (1989) 1.36
Small oligomers of immunoglobulin E (IgE) cause large-scale clustering of IgE receptors on the surface of rat basophilic leukemia cells. J Cell Biol (1984) 1.35
Studies with a monoclonal antibody to the beta subunit of the receptor with high affinity for immunoglobulin E. Mol Immunol (1988) 1.35
Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E. Proc Natl Acad Sci U S A (1988) 1.32
Cell cycle-associated changes in receptors for IgE during growth and differentiation of a rat basophilic leukemia cell line. J Exp Med (1975) 1.29
A Waldenström macroglobulin which binds nitrophenyl ligands. J Biol Chem (1969) 1.26
Aggregation of IgE-receptor complexes on rat basophilic leukemia cells does not change the intrinsic affinity but can alter the kinetics of the ligand-IgE interaction. Biochemistry (1992) 1.23
Kinetics of multivalent antigen DNP-BSA binding to IgE-Fc epsilon RI in relationship to the stimulated tyrosine phosphorylation of Fc epsilon RI. J Immunol (1998) 1.22
Noncytotoxic IgE-mediated release of histamine and serotonin from murine mastocytoma cells. J Immunol (1977) 1.22
Structural aspects of the association of FcepsilonRI with detergent-resistant membranes. J Biol Chem (1999) 1.20
Quantitative relationships between aggregation of IgE receptors, generation of intracellular signals, and histamine secretion in rat basophilic leukemia (2H3) cells. Enhanced responses with heavy water. J Biol Chem (1986) 1.20
The receptor on mast cells and related cells with high affinity for IgE. Contemp Top Mol Immunol (1983) 1.19
Myeloma proteins and antibodies. Am J Med (1969) 1.18
Binding properties of a Waldenström macroglobulin antibody. J Biol Chem (1968) 1.18
Initial characterization of the calcium channel activated by the cross-linking of the receptors for immunoglobulin E. J Biol Chem (1984) 1.17
Affinity labeling of a mouse myeloma protein which binds nitrophenyl ligands. Sequence and position of a labeled tryptic peptide. Biochemistry (1970) 1.17
The chemistry of the immunoglobulins. JAMA (1967) 1.17
Electron microscopic localization of immunoglobulin E on the surface membrane of human basophils. J Exp Med (1971) 1.15
Phospholipids stabilize the interaction between the alpha and beta subunits of the solubilized receptor for immunoglobulin E. Biochemistry (1982) 1.15
Interaction of IgE with rat basophilic leukemia cells. IV. Antibody-induced redistribution of IgE receptors. J Immunol (1974) 1.15
Isolation of IgE from reaginic rat serum. J Immunol (1974) 1.14
How does the plasma membrane participate in cellular signaling by receptors for immunoglobulin E? Biophys Chem (1999) 1.14
Qualitative characteristics of histamine release from human basophils by covalently cross-linked IgE. J Immunol (1981) 1.13
The unique domain as the site on Lyn kinase for its constitutive association with the high affinity receptor for IgE. J Biol Chem (1997) 1.12
Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives. J Med Chem (1983) 1.12
Analysis of the rate-limiting step in a ligand-cell receptor interaction: the immunoglobulin E system. Biochemistry (1983) 1.12
A previously unrecognized subunit of the receptor for immunoglobulin E. Biochemistry (1983) 1.12
The Fc segment of IgE influences the kinetics of dissociation of a symmetrical bivalent ligand from cyclic dimeric complexes. Biochemistry (1996) 1.11
Reconstitution of the receptor for immunoglobulin E into liposomes. Conditions for incorporation of the receptor into vesicles. J Biol Chem (1982) 1.11
Cross-linking of IgE-receptor complexes at the cell surface: synthesis and characterization of a long bivalent hapten that is capable of triggering mast cells and rat basophilic leukemia cells. Mol Immunol (1986) 1.11
Catalytic unit of adenlyate cyclase: purification and identification by affinity crosslinking. Proc Natl Acad Sci U S A (1985) 1.10
Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors. J Immunol (1988) 1.10
Cross-linking of immunoglobulin E-receptor complexes induces their interaction with the cytoskeleton of rat basophilic leukemia cells. J Immunol (1986) 1.10
The effect of antigen on antibodies: recent studies. Contemp Top Mol Immunol (1978) 1.10
Dynamics of signal transduction after aggregation of cell-surface receptors: studies on the type I receptor for IgE. Proc Natl Acad Sci U S A (1994) 1.09
Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading. Proc Natl Acad Sci U S A (2001) 1.09
Ionophore A-23187 induced histamine release from rat mast cells and rat basophil leukemia (RBL-1) cells. J Immunol (1975) 1.09
Phase separation of the receptor for immunoglobulin E and its subunits in Triton X-114. J Biol Chem (1984) 1.07
Simultaneous cross-linking by two nontriggering bivalent ligands causes synergistic signaling of IgE Fc epsilon RI complexes. J Immunol (1995) 1.07
Secretion from rat basophilic leukaemia cells induced by calcium ionophores. Effect of pH and metabolic inhibition. Biochim Biophys Acta (1981) 1.05
Isolation of homologous and heterologous complexes between catalytic and regulatory components of adenylate cyclase by forskolin-Sepharose. FEBS Lett (1983) 1.04
[Ultrastructure of the luminal surface of Fallopian tube in the scanning electron microscope]. Arch Gynakol (1972) 1.04
Evidence supporting a role for microfilaments in regulating the coupling between poorly dissociable IgE-Fc epsilonRI aggregates downstream signaling pathways. Biochemistry (1997) 1.04
Cross-linking of IgE-receptor complexes by rigid bivalent antigens greater than 200 A in length triggers cellular degranulation. J Cell Biol (1988) 1.04
Interaction of aggregated native and mutant IgE receptors with the cellular skeleton. Proc Natl Acad Sci U S A (1992) 1.03
Mutant RBL mast cells defective in Fc epsilon RI signaling and lipid raft biosynthesis are reconstituted by activated Rho-family GTPases. Mol Biol Cell (2000) 1.03
Unexpected signals in a system subject to kinetic proofreading. Proc Natl Acad Sci U S A (2001) 1.03
Bivalent ligand dissociation kinetics from receptor-bound immunoglobulin E: evidence for a time-dependent increase in ligand rebinding at the cell surface. Biochemistry (1991) 1.03
Cholera toxin increases the rate of antigen-stimulated calcium influx in rat basophilic leukemia cells. J Biol Chem (1988) 1.03
Transmembrane signaling by the high-affinity IgE receptor on membrane preparations. Proc Natl Acad Sci U S A (1992) 1.02