Published in Annu Rev Biophys Bioeng on January 01, 1983
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO J (1985) 20.39
DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein. Nucleic Acids Res (1985) 4.84
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J (1986) 4.47
Characterization of two genes required for the position-effect control of yeast mating-type genes. EMBO J (1984) 3.30
Distinct binding sites for zinc and double-stranded RNA in the reovirus outer capsid protein sigma 3. Mol Cell Biol (1988) 1.96
Molecular cloning of cDNA coding for rat proliferating cell nuclear antigen (PCNA)/cyclin. EMBO J (1987) 1.75
TFIIIA and homologous genes. The 'finger' proteins. Nucleic Acids Res (1986) 1.74
Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes. Mol Cell Biol (1988) 1.52
Extrinsic interactions dominate helical propensity in coupled binding and folding of the lactose repressor protein hinge helix. Biochemistry (2006) 1.02
A gene that encodes a protein consisting solely of zinc finger domains is preferentially expressed in transformed mouse cells. Mol Cell Biol (1990) 0.94
Structure, expression and chromosomal localization of Zfp-1, a murine zinc finger protein gene. Nucleic Acids Res (1989) 0.93
Asp-286----Asn-286 in polyomavirus large T antigen relaxes the specificity of binding to the polyomavirus origin. J Virol (1989) 0.91
Solvent content of protein crystals. J Mol Biol (1968) 106.07
Comparison of the predicted and observed secondary structure of T4 phage lysozyme. Biochim Biophys Acta (1975) 17.03
The helix-turn-helix DNA binding motif. J Biol Chem (1989) 6.87
Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect. Science (1992) 6.51
Structural origins of high-affinity biotin binding to streptavidin. Science (1989) 5.37
Structure of the cro repressor from bacteriophage lambda and its interaction with DNA. Nature (1981) 5.24
Structural basis of amino acid alpha helix propensity. Science (1993) 4.36
Enhancement of the method of molecular replacement by incorporation of known structural information. Acta Crystallogr D Biol Crystallogr (1994) 4.26
Structural basis of DNA-protein recognition. Trends Biochem Sci (1989) 3.95
Three-dimensional structure of tosyl-alpha-chymotrypsin. Nature (1967) 3.57
DNA-binding proteins. Science (1983) 3.56
The molecular basis of DNA-protein recognition inferred from the structure of cro repressor. Nature (1982) 3.56
Three-dimensional structure of beta-galactosidase from E. coli. Nature (1994) 3.46
A relationship between protein stability and protein function. Proc Natl Acad Sci U S A (1995) 3.44
A mutant T4 lysozyme displays five different crystal conformations. Nature (1990) 3.07
Structure of bacteriophage T4 lysozyme refined at 1.7 A resolution. J Mol Biol (1987) 3.02
Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. Proc Natl Acad Sci U S A (1992) 2.89
Structural similarity in the DNA-binding domains of catabolite gene activator and cro repressor proteins. Proc Natl Acad Sci U S A (1982) 2.84
Structure of thermolysin refined at 1.6 A resolution. J Mol Biol (1982) 2.84
Structure of crystalline -chymotrypsin. II. A preliminary report including a hypothesis for the activation mechanism. J Mol Biol (1968) 2.72
Accurate calculation of the density of proteins. Acta Crystallogr D Biol Crystallogr (2000) 2.70
Control of enzyme activity by an engineered disulfide bond. Science (1989) 2.70
Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme. J Mol Biol (1995) 2.55
Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences. J Mol Biol (1993) 2.50
Structure and X-ray amino acid sequence of a bacteriochlorophyll A protein from Prosthecochloris aestuarii refined at 1.9 A resolution. J Mol Biol (1986) 2.45
Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3. Nature (1988) 2.32
Protein-DNA interaction. No code for recognition. Nature (1988) 2.31
Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme. Biochemistry (1991) 2.31
Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme. Proc Natl Acad Sci U S A (2000) 2.25
The conformation of thermolysin. J Biol Chem (1974) 2.25
Structural analysis of zinc substitutions in the active site of thermolysin. Protein Sci (1995) 2.24
Stabilization of phage T4 lysozyme by engineered disulfide bonds. Proc Natl Acad Sci U S A (1989) 2.17
Covalent structure of a group-specific protease from rat small intestine. Appendix: crystallographic data for a group specific protease from rat intestine. Biochemistry (1978) 2.17
Ancestral lysozymes reconstructed, neutrality tested, and thermostability linked to hydrocarbon packing. Nature (1990) 2.14
Toroidal structure of lambda-exonuclease. Science (1997) 2.14
Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein. Biochemistry (1987) 2.12
Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry (1995) 2.10
A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene. Nature (1992) 2.10
Structure of the DNA-binding region of lac repressor inferred from its homology with cro repressor. Proc Natl Acad Sci U S A (1982) 2.09
Structure and function of the methionine aminopeptidases. Biochim Biophys Acta (2000) 2.09
Substantial increase of protein stability by multiple disulphide bonds. Nature (1989) 2.08
Second-site revertants of an inactive T4 lysozyme mutant restore activity by restructuring the active site cleft. Biochemistry (1991) 2.03
The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect. Protein Sci (1998) 2.02
Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature (1987) 2.01
Intrahelical hydrogen bonding of serine, threonine and cysteine residues within alpha-helices and its relevance to membrane-bound proteins. J Mol Biol (1984) 2.00
Crystal structure of the superantigen staphylococcal enterotoxin type A. EMBO J (1995) 1.99
Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme. J Mol Biol (1994) 1.95
Three-dimensional structure of human basic fibroblast growth factor. Proc Natl Acad Sci U S A (1991) 1.94
Enhanced protein thermostability from designed mutations that interact with alpha-helix dipoles. Nature (1988) 1.89
Kinetic studies on Cro repressor-operator DNA interaction. J Mol Biol (1987) 1.85
A structural basis for processivity. Protein Sci (2001) 1.85
Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme. Biochemistry (1993) 1.80
Many gene-regulatory proteins appear to have a similar alpha-helical fold that binds DNA and evolved from a common precursor. J Mol Evol (1983) 1.80
Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry (1991) 1.79
Type II restriction endonucleases: structural, functional and evolutionary relationships. Curr Opin Chem Biol (1999) 1.79
The structure of thermolysin: an electron density map at 2-3 A resolution. J Mol Biol (1972) 1.77
Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes. Proc Natl Acad Sci U S A (1995) 1.76
Thiol-disulfide exchange is involved in the catalytic mechanism of peptide methionine sulfoxide reductase. Proc Natl Acad Sci U S A (2000) 1.76
Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry (1991) 1.76
Energetic origins of specificity of ligand binding in an interior nonpolar cavity of T4 lysozyme. Biochemistry (1995) 1.75
Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme. J Mol Biol (1992) 1.73
Structure-based design of a lysozyme with altered catalytic activity. Nat Struct Biol (1995) 1.73
Structure and mechanism of peptide methionine sulfoxide reductase, an "anti-oxidation" enzyme. Biochemistry (2000) 1.72
Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive. Protein Eng (1995) 1.68
Atomic co-ordinates for tosyl-alpha-chymotrypsin. Biochem Biophys Res Commun (1969) 1.67
Molecular basis of thermostability in the lysozyme from bacteriophage T4. Nature (1979) 1.66
A crystallographic study of the complex of phosphoramidon with thermolysin. A model for the presumed catalytic transition state and for the binding of extended substances. J Mol Biol (1977) 1.65
Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b. Protein Sci (1997) 1.64
Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex. Proc Natl Acad Sci U S A (1990) 1.63
Reversible lattice repacking illustrates the temperature dependence of macromolecular interactions. J Mol Biol (2001) 1.60
An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides. Biochemistry (1984) 1.59
Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths. Proteins (1991) 1.57
A test of the "jigsaw puzzle" model for protein folding by multiple methionine substitutions within the core of T4 lysozyme. Proc Natl Acad Sci U S A (1996) 1.56
Structure of Escherichia coli exonuclease I suggests how processivity is achieved. Nat Struct Biol (2000) 1.55
Structure of a bacteriochlorophyll a-protein from the green photosynthetic bacterium Prosthecochloris aestuarii. J Mol Biol (1979) 1.54
The three dimensional structure of the lysozyme from bacteriophage T4. Proc Natl Acad Sci U S A (1974) 1.52
A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme. Science (1993) 1.50
Hydrophobic packing in T4 lysozyme probed by cavity-filling mutants. Proc Natl Acad Sci U S A (1989) 1.50
Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc Natl Acad Sci U S A (1992) 1.49
Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator. Proc Natl Acad Sci U S A (2001) 1.49
Comparison of the structures of cro and lambda repressor proteins from bacteriophage lambda. J Mol Biol (1983) 1.48
Relation between hen egg white lysozyme and bacteriophage T4 lysozyme: evolutionary implications. J Mol Biol (1981) 1.46
Comparison of the structures of carboxypeptidase A and thermolysin. J Biol Chem (1977) 1.46
Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis. Biochemistry (1981) 1.46
A systematic approach to the comparison of protein structures. J Mol Biol (1980) 1.45
Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J Mol Biol (1995) 1.43
Structure of toxic shock syndrome toxin 1. Biochemistry (1993) 1.43
Size versus polarizability in protein-ligand interactions: binding of noble gases within engineered cavities in phage T4 lysozyme. J Mol Biol (2000) 1.43
Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59. Biochemistry (1992) 1.42
Toward a simplification of the protein folding problem: a stabilizing polyalanine alpha-helix engineered in T4 lysozyme. Biochemistry (1991) 1.42
Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues. Biochemistry (1987) 1.42
Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases. Biochemistry (1984) 1.40
Determination of molecular weight from protein crystals. J Mol Biol (1974) 1.40