Published in Am J Med on January 01, 1984
Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging. J Clin Invest (1989) 3.92
Persistent infection of chimpanzees with human T-lymphotropic virus type III/lymphadenopathy-associated virus: a potential model for acquired immunodeficiency syndrome. J Virol (1986) 2.65
Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack. Proc Natl Acad Sci U S A (1987) 2.53
Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men. J Clin Invest (1990) 2.51
Laboratory control values for CD4 and CD8 T lymphocytes. Implications for HIV-1 diagnosis. Clin Exp Immunol (1992) 2.27
Mycobacterial disease, immunosuppression, and acquired immunodeficiency syndrome. Clin Microbiol Rev (1989) 2.20
The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value. Clin Exp Immunol (1992) 1.98
Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro. Proc Natl Acad Sci U S A (1986) 1.90
Human immunodeficiency virus infection induces both polyclonal and virus-specific B cell activation. J Clin Invest (1992) 1.84
Optimal conditions for recovery of the human immunodeficiency virus from peripheral blood mononuclear cells. J Clin Microbiol (1988) 1.78
Depletion of the surface CD4 molecule by the envelope protein of human immunodeficiency virus expressed in a human CD4+ monocytoid cell line. J Virol (1989) 1.73
Apoptosis induced in CD4+ cells expressing gp160 of human immunodeficiency virus type 1. J Virol (1994) 1.67
Cryptococcal meningitis and cerebral toxoplasmosis in a patient with acquired immune deficiency syndrome. J Neurol Neurosurg Psychiatry (1986) 1.67
The Vancouver Lymphadenopathy-AIDS Study: 3. Relation of HTLV-III seropositivity, immune status and lymphadenopathy. Can Med Assoc J (1985) 1.59
T4 lymphopenia in patients with active pulmonary tuberculosis. Clin Exp Immunol (1985) 1.50
Methylation as a modulator of expression of human immunodeficiency virus. J Virol (1987) 1.47
Impairment of polymorphonuclear leucocyte function in patients with acquired immunodeficiency syndrome and with lymphadenopathy syndrome. Clin Exp Immunol (1986) 1.37
Inactivation of suppressor T-cell activity by nontoxic monophosphoryl lipid A. Infect Immun (1988) 1.31
Cytokine interactions in human immunodeficiency virus-infected individuals: roles of interleukin (IL)-2, IL-12, and IL-15. J Exp Med (1995) 1.25
Influence of the murine MHC (H-2) on Friend leukemia virus-induced immunosuppression. J Exp Med (1986) 1.15
Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions. Microbiol Rev (1996) 1.13
Defective in vitro growth of the hemopoietic progenitor cells in the acquired immunodeficiency syndrome. J Clin Invest (1987) 1.13
Recent clinical isolates of cytomegalovirus suppress human cytomegalovirus-specific human leukocyte antigen-restricted cytotoxic T-lymphocyte activity. J Virol (1986) 1.13
Beta 2-microglobulin and neopterin: predictive markers for human immunodeficiency virus type 1 infection in children? J Clin Microbiol (1990) 1.11
Elevated soluble CD8 levels in sera of human immunodeficiency virus-infected populations. J Clin Microbiol (1989) 1.03
HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression. J Clin Invest (1996) 1.02
The acquired immunodeficiency syndrome (AIDS). J Clin Invest (1985) 1.00
Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guérin (BCG) vaccine in HIV-uninfected infants. Immunology (2009) 0.99
Clonal analysis of T lymphocytes in the acquired immunodeficiency syndrome. Evidence for an abnormality affecting individual helper and suppressor T cells. J Clin Invest (1985) 0.99
Presence of CD3+CD8+Bcl-2(low) lymphocytes undergoing apoptosis and activated macrophages in lymph nodes of HIV-1+ patients. Am J Pathol (1995) 0.95
Demonstration of defective C3-receptor-mediated clearance by the reticuloendothelial system in patients with acquired immunodeficiency syndrome. J Clin Invest (1987) 0.92
Immune response in shipyard workers with x ray abnormalities consistent with asbestos exposure. Br J Ind Med (1988) 0.91
Abnormalities of interleukin 2 receptor expression associated with decreased antigen-induced lymphocyte proliferation in patients with AIDS and related disorders. Clin Exp Immunol (1987) 0.89
Lysis of CD4+ lymphocytes by non-HLA-restricted cytotoxic T lymphocytes from HIV-infected individuals. Clin Exp Immunol (1993) 0.89
Downregulation of interferon alpha but not gamma receptor expression in vivo in the acquired immunodeficiency syndrome. J Clin Invest (1988) 0.88
Defective T-cell colony formation and IL-2 receptor expression at all stages of HIV infection. Clin Exp Immunol (1988) 0.86
Elevated levels of CD4 antigen in sera of human immunodeficiency virus-infected populations. J Clin Microbiol (1990) 0.83
Antigen-specific primary cytotoxic T lymphocyte (CTL) responses in acquired immune deficiency syndrome (AIDS) and AIDS-related complexes (ARC). Clin Exp Immunol (1985) 0.82
Delay in cART initiation results in persistent immune dysregulation and poor recovery of T-cell phenotype despite a decade of successful HIV suppression. PLoS One (2014) 0.80
Dichotomy of two CD8+ lymphocyte subsets in HIV infection. Depletion of CD8+ CD3- and expansion of CD8+ CD3+ subsets: consequence on the CD4/CD8 ratio. Clin Exp Immunol (1991) 0.79
Translational HIV-1 research: from routine diagnostics to new virology insights in Amsterdam, the Netherlands during 1983-2013. Retrovirology (2013) 0.76
Progressive cellular immune impairment leading to development of AIDS: two-year prospective study of HIV infection in drug addicts. Clin Exp Immunol (1988) 0.75
Diagnostic utility of lymphocyte subset analysis in AIDS case finding. CMAJ (1986) 0.75
T-lymphocyte subsets in apparently healthy nigerian children. Int J Pediatr (2010) 0.75
Preservation of clonal heterogeneity of the Pneumocystis carinii-specific CD4 T cell repertoire in HIV infected, asymptomatic individuals. Clin Exp Immunol (2002) 0.75
Hepatitis B immune globulin as treatment of CMV infections in patients with AIDS. J Natl Med Assoc (1986) 0.75
The Multicenter AIDS Cohort Study: rationale, organization, and selected characteristics of the participants. Am J Epidemiol (1987) 17.36
Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med (1997) 16.44
Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat Med (1996) 10.49
Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis (1999) 9.81
Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression. J Virol (1989) 9.37
Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation (2001) 7.47
The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N Engl J Med (1990) 6.94
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med (1996) 5.96
Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 5.30
Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy. Nat Genet (1999) 5.04
Risk factors for seroconversion to human immunodeficiency virus among male homosexuals. Results from the Multicenter AIDS Cohort Study. Lancet (1987) 4.33
Spinal manipulative therapy is an independent risk factor for vertebral artery dissection. Neurology (2003) 4.32
The risk of Pneumocystis carinii pneumonia among men infected with human immunodeficiency virus type 1. Multicenter AIDS Cohort Study Group. N Engl J Med (1990) 4.25
Human immunodeficiency virus type 1 infection in homosexual men who remain seronegative for prolonged periods. N Engl J Med (1989) 4.20
Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma. N Engl J Med (1996) 4.13
Elevated levels of CD38+ CD8+ T cells in HIV infection add to the prognostic value of low CD4+ T cell levels: results of 6 years of follow-up. The Los Angeles Center, Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr (1993) 3.91
A novel mutation in the potassium channel gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome. Nat Genet (1997) 3.79
Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1989) 3.78
Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Multicenter AIDS Cohort Study. J Infect Dis (2000) 3.73
A deletion in the PHYD gene of the Arabidopsis Wassilewskija ecotype defines a role for phytochrome D in red/far-red light sensing. Plant Cell (1997) 3.66
Predictors of the acquired immunodeficiency syndrome developing in a cohort of seropositive homosexual men. N Engl J Med (1987) 3.58
AIDS--an immunologic reevaluation. N Engl J Med (1984) 3.53
The acquired immunodeficiency syndrome. Ann Intern Med (1983) 3.49
Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology (1993) 3.37
The effects on survival of early treatment of human immunodeficiency virus infection. N Engl J Med (1992) 3.32
Mutations in the laminin alpha 2-chain gene (LAMA2) cause merosin-deficient congenital muscular dystrophy. Nat Genet (1995) 3.05
Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II). J Clin Invest (1965) 3.00
T-cell subset alterations in HIV-infected homosexual men: NIAID Multicenter AIDS cohort study. Clin Immunol Immunopathol (1989) 3.00
Prevalence of HIV infection among former commercial plasma donors in rural eastern China. Health Policy Plan (2001) 2.94
A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the Multicenter AIDS Cohort Study. Lancet (1990) 2.89
Myosin isoenzyme redistribution in chronic heart overload. Nature (1979) 2.89
Three myosin heavy-chain isozymes appear sequentially in rat muscle development. Nature (1981) 2.88
The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. J Clin Invest (1999) 2.77
Limited periods of gene expression in immunoglobulin-synthesizing cells. Science (1969) 2.77
Myoblast transplantation for heart failure. Lancet (2001) 2.71
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice. Hum Mol Genet (2000) 2.67
Thalidomide for the treatment of oral aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group. N Engl J Med (1997) 2.55
Identification of mutations in the gene encoding lamins A/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD1B). Hum Mol Genet (2000) 2.52
Cardiac myosin binding protein-C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy. Nat Genet (1995) 2.52
Determinants of heterogeneous adherence to HIV-antiretroviral therapies in the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr (2001) 2.51
Relation between sexual practices and T-cell subsets in homosexually active men. Lancet (1983) 2.46
CD8+ T-lymphocyte activation in HIV-1 disease reflects an aspect of pathogenesis distinct from viral burden and immunodeficiency. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 2.45
HIV-1, HIV-2, and HTLV-I infection in high-risk groups in Brazil. N Engl J Med (1989) 2.45
HIV-1 infection in commercial plasma donors in China. Lancet (1995) 2.42
Accelerated course of human immunodeficiency virus infection in gay men who conceal their homosexual identity. Psychosom Med (1996) 2.40
Children's health and the environment: a new agenda for prevention research. Environ Health Perspect (1998) 2.40
Malignant melanoma. Effects of an early structured psychiatric intervention, coping, and affective state on recurrence and survival 6 years later. Arch Gen Psychiatry (1993) 2.38
Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals. J Clin Invest (1987) 2.37
Prognostic significance of plasma markers of immune activation, HIV viral load and CD4 T-cell measurements. AIDS (1998) 2.33
THE METABOLISM OF NORMAL PLASMA PROTEINS AND GAMMA-MYELOMA PROTEIN IN MICE BEARING PLASMA-CELL TUMORS. J Clin Invest (1961) 2.32
Factors associated with prevalent human immunodeficiency virus (HIV) infection in the Multicenter AIDS Cohort Study. Am J Epidemiol (1987) 2.29
Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV. J Immunol (1989) 2.27
Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle. Proc Natl Acad Sci U S A (1984) 2.26
Guidelines for the study of familial dilated cardiomyopathies. Collaborative Research Group of the European Human and Capital Mobility Project on Familial Dilated Cardiomyopathy. Eur Heart J (1999) 2.24
The effects of establishment practices, knowledge and attitudes on condom use among Filipina sex workers. AIDS Care (1998) 2.23
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse. Hum Mol Genet (1999) 2.20
Diagnostic value of electrocardiography and echocardiography for familial hypertrophic cardiomyopathy in genotyped children. Eur Heart J (1998) 2.20
Imagery rehearsal therapy for chronic nightmares in sexual assault survivors with posttraumatic stress disorder: a randomized controlled trial. JAMA (2001) 2.20
Myosin isoenzyme changes in several models of rat cardiac hypertrophy. Circ Res (1981) 2.20
Neuropsychological performance in HIV-1-infected homosexual men: The Multicenter AIDS Cohort Study (MACS) Neurology (1990) 2.17
Cervical dystonia: clinical findings and associated movement disorders. Neurology (1991) 2.16
Variables that affect assays for plasma cytokines and soluble activation markers. Clin Diagn Lab Immunol (1999) 2.15
Association of race and gender with HIV-1 RNA levels and immunologic progression. J Acquir Immune Defic Syndr (2000) 2.13
The Vancouver Lymphadenopathy-AIDS Study: 4. Effects of exposure factors, cofactors and HTLV-III seropositivity on number of helper T cells. Can Med Assoc J (1985) 2.11
Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity. J Immunol (1987) 2.11
Antibodies and immunoglobulins. II. Normal development and changes in disease. JAMA (1965) 2.10
CD4 percentage, CD4 number, and CD4:CD8 ratio in HIV infection: which to choose and how to use. J Acquir Immune Defic Syndr (1989) 2.10
Topical treatment of cutaneous lesions of acquired immunodeficiency syndrome-related Kaposi sarcoma using alitretinoin gel: results of phase 1 and 2 trials. Arch Dermatol (2000) 2.09
The immunoglobulins of mice. VI. Response to immunization. J Immunol (1965) 2.08
Development of a compact fast CCD camera and resonant soft x-ray scattering endstation for time-resolved pump-probe experiments. Rev Sci Instrum (2011) 2.05
Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy. J Cell Sci (2001) 2.05
Clinical features and prognostic implications of familial hypertrophic cardiomyopathy related to the cardiac myosin-binding protein C gene. Circulation (1998) 2.04
A study of sexual behavior among rural residents of China. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 2.02
Medical care costs of AIDS in Massachusetts. JAMA (1986) 1.94
Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure. J Clin Invest (1990) 1.94
Transmission of HIV from injecting drug users to their wives in India. Int J STD AIDS (2000) 1.94
Familial hypertrophic cardiomyopathy: from mutations to functional defects. Circ Res (1998) 1.92
Saccades in presymptomatic and early stages of Huntington disease. Neurology (2006) 1.92
Immunological studies of homosexual men with immunodeficiency and Kaposi's sarcoma. Clin Immunol Immunopathol (1983) 1.91
Norepinephrine accelerates HIV replication via protein kinase A-dependent effects on cytokine production. J Immunol (1998) 1.90
Alpha-skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts. Circ Res (1986) 1.90
Pim-1: a serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis. J Vet Sci (2001) 1.89
Effect of zidovudine and Pneumocystis carinii pneumonia prophylaxis on progression of HIV-1 infection to AIDS. The Multicenter AIDS Cohort Study. Lancet (1991) 1.89
Computerized and conventional neuropsychological assessment of HIV-1-infected homosexual men. Neurology (1991) 1.88
Subacute sclerosing panencephalitis: a zoonosis following aberrant measles. Lancet (1970) 1.88
Early effects of HIV on CD4 lymphocytes in vivo. J Immunol (1987) 1.87
Elevated IFN-gamma and decreased IL-2 gene expression are associated with HIV infection. J Immunol (1993) 1.86
Clinical and molecular genetic spectrum of autosomal dominant Emery-Dreifuss muscular dystrophy due to mutations of the lamin A/C gene. Ann Neurol (2000) 1.84
Different mutations in the LMNA gene cause autosomal dominant and autosomal recessive Emery-Dreifuss muscular dystrophy. Am J Hum Genet (2000) 1.84
Contractile protein isozymes in muscle development: identification of an embryonic form of myosin heavy chain. Proc Natl Acad Sci U S A (1979) 1.80