Published in Cancer Res on October 01, 1980
Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release. J Clin Invest (1983) 1.16
A re-assessment of the role of protein kinase C in glucose-stimulated insulin secretion. Biochem J (1987) 1.10
Effects of protein kinase C activation on the regulation of the stimulus-secretion coupling in pancreatic beta-cells. Biochem J (1989) 1.06
Phorbol ester stimulation of insulin release and secretory-granule protein phosphorylation in a transplantable rat insulinoma. Biochem J (1984) 0.97
Comparison of effects of phorbol esters and glucose on protein kinase C activation and insulin secretion in pancreatic islets. Biochem J (1989) 0.92
Evidence that phorbol ester interferes with stimulated Ca2+ redistribution by activating Ca2+ efflux in neutrophil leucocytes. Biochem J (1985) 0.92
An inhibitory role for polyamines in protein kinase C activation and insulin secretion in mouse pancreatic islets. Biochem J (1986) 0.91
Effects of a phorbol ester and clomiphene on protein phosphorylation and insulin secretion in rat pancreatic islets. Biochem J (1988) 0.90
Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells. Biochem J (1985) 0.88
Phorbol-ester-induced down-regulation of protein kinase C in mouse pancreatic islets. Potentiation of phase 1 and inhibition of phase 2 of glucose-induced insulin secretion. Biochem J (1990) 0.81
Comparison of the inhibition of insulin release by activation of adenosine and alpha 2-adrenergic receptors in rat beta-cells. Biochem J (1989) 0.81
Stimulation by glucose of cyclic AMP accumulation in mouse pancreatic islets is mediated by protein kinase C. Biochem J (1988) 0.80
Effects of the phorbol ester phorbol 12-myristate 13-acetate (PMA) on islet-cell responsiveness. Biochem J (1991) 0.79
Autocrine Signaling Underlies Fast Repetitive Plasma Membrane Translocation of Conventional and Novel Protein Kinase C Isoforms in β Cells. J Biol Chem (2016) 0.76
Regulation of Na+/Ca2+ exchange in the rat pancreatic B cell. Biochem J (1992) 0.76
Activation of protein kinase C partially alleviates noradrenaline inhibition of insulin secretion. Biochem J (1993) 0.75
Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem (1982) 16.71
Pancreatic beta-cell web: its possible role in insulin secretion. Science (1972) 2.63
A possible role for the adenylcyclase system in insulin secretion. J Clin Invest (1967) 2.54
Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol (2007) 2.13
Synergistic functions of phorbol ester and calcium in serotonin release from human platelets. Biochem Biophys Res Commun (1983) 2.03
The stimulus-secretion coupling of glucose-induced insulin release. 3. Uptake of 45 calcium by isolated islets of Langerhans. Endocrinology (1971) 2.01
Insulin release: the fuel hypothesis. Metabolism (1979) 1.84
The pharmacokinetics of oxybutynin in man. Eur J Clin Pharmacol (1988) 1.83
L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase. Nature (1980) 1.81
The stimulus-secretion coupling of glucose-induced insulin release. V. The participation of a microtubular-microfilamentous system. Diabetes (1971) 1.66
The stimulus-secretion coupling of glucose-induced insulin release. VII. A proposed site of action for adenosine-3',5'-cyclic monophosphate. J Clin Invest (1972) 1.62
Insulin secretion: multifactorial regulation for a single process of release. The Minkowski award lecture delivered on September 7, 1972 before the European Association for the study of Diabetes at Madrid, Spain. Diabetologia (1973) 1.62
Calmodulin activation of adenylate cyclase in pancreatic islets. Science (1979) 1.58
Stimulus-secretion coupling of glucose-induced insulin release. X. Effect of glucose on 45 Ca efflux from perifused islets. Am J Physiol (1973) 1.57
The stimulus-secretion coupling of glucose-induced insulin release. Effect of exogenous pyruvate on islet function. Biochem J (1978) 1.52
The stimulus-secretion coupling of glucose-induced insulin release. XXXV. The links between metabolic and cationic events. Diabetologia (1979) 1.52
The stimulus-secretion coupling of glucose-induced insulin release. I. Interaction of epinephrine and alkaline earth cations. J Lab Clin Med (1970) 1.49
Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line. Diabetologia (2006) 1.43
Stimulation of insulin secretion by noncarbohydrate metabolites. J Lab Clin Med (1968) 1.38
The stimulus-secretion coupling of glucose-induced insulin release. Metabolic effects of menadione in isolated islets. Eur J Biochem (1978) 1.36
The stimulus-secretion coupling of glucose-induced insulin release. XIV. Glucose regulation of insular biosynthetic activity. Endocrinology (1973) 1.33
Determinants of the selective toxicity of alloxan to the pancreatic B cell. Proc Natl Acad Sci U S A (1982) 1.32
Patterns of calcium localization in pancreatic endocrine cells. J Cell Sci (1976) 1.30
Effect of adrenaline and glucose on release of glucagon and insulin in vitro. Nat New Biol (1971) 1.29
Effect of fasting upon insulin secretion in the rat. Am J Physiol (1967) 1.27
Effect of glucose on K+ handling by pancreatic islets. FEBS Lett (1977) 1.27
Dynamics of O2 consumption in rat pancreatic islets. Diabetologia (1980) 1.24
Nutrient and hormone-neurotransmitter stimuli induce hydrolysis of polyphosphoinositides in rat pancreatic islets. Endocrinology (1984) 1.24
Glucose-induced changes in cytosolic ATP content in pancreatic islets. Biochim Biophys Acta (1987) 1.24
Regulation of calcium fluxes and their regulatory roles in pancreatic islets. Ann N Y Acad Sci (1978) 1.23
Pleiotropic effects of fatty acids on pancreatic beta-cells. J Cell Physiol (2003) 1.21
Insulin secretion by isolated islets in presence of glucose, insulin and anti-insulin serum. Proc Soc Exp Biol Med (1967) 1.21
A computational strategy for the deconvolution of NMR spectra with multiplet structures and constraints: analysis of overlapping 13C-2H multiplets of 13C enriched metabolites from cell suspensions incubated in deuterated media. Magn Reson Med (1996) 1.21
Hexose metabolism in pancreatic islets. Absence of glucose-6-phosphatase in rat islet cells. Mol Cell Endocrinol (1987) 1.19
Enteropathy precedes type 1 diabetes in the BB rat. Gut (2004) 1.19
The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets. Mol Cell Endocrinol (1980) 1.19
Role of microtubules in the phasic pattern of insulin release. Ann N Y Acad Sci (1975) 1.19
Kinetics and subcellular localization of specific [3H]phorbol 12, 13-dibutyrate binding by mouse brain. Cancer Res (1981) 1.18
Insulinotropic action of methyl pyruvate: enzymatic and metabolic aspects. Arch Biochem Biophys (1996) 1.17
Interference of glycogenolysis with glycolysis in pancreatic islets from glucose-infused rats. J Clin Invest (1993) 1.17
Stimulation of pancreatic islet metabolism and insulin release by a nonmetabolizable amino acid. Proc Natl Acad Sci U S A (1981) 1.16
Role of electrothrombosis in aneurysm treatment with Guglielmi detachable coils: an in vitro scanning electron microscopic study. AJNR Am J Neuroradiol (2001) 1.15
The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state. Biochem J (1984) 1.15
Alloxan toxicity to the pancreatic B-cell. A new hypothesis. Biochem Pharmacol (1982) 1.13
Differences in glucose handling by pancreatic A- and B-cells. J Biol Chem (1984) 1.13
Multiple effects of leucine on glucagon, insulin, and somatostatin secretion from the perfused rat pancreas. Endocrinology (1985) 1.12
Regulation of calcium fluxes in rat pancreatic islets: calcium extrusion by sodium-calcium countertransport. J Membr Biol (1980) 1.11
The stimulus-secretion coupling of glucose-induced insulin release: fuel metabolism in islets deprived of exogenous nutrient. Arch Biochem Biophys (1983) 1.11
The effect of mannoheptulose on the phosphorylation of glucose and the secretion of insulin by islets of Langerhans. Metabolism (1968) 1.11
Calcium antagonists and islet function. XI. Effect of nifedipine. Horm Res (1977) 1.10
Pancreatic polypeptide: a possible role in the regulation of food intake in the mouse. Hypothesis. Experientia (1977) 1.10
The stimulus-secretion coupling of amino acid-induced insulin release: metabolism and cationic effects of leucine. Diabetes (1980) 1.10
Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood. Metabolism (1999) 1.10
Distribution and cellular localization of the serotonin type 2C receptor messenger RNA in human brain. Neuroscience (1999) 1.09
Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells. Endocrinology (2009) 1.09
The stimulus-secretion coupling of glucose-induced insulin release. Insulin release due to glycogenolysis in glucose-deprived islets. Biochem J (1977) 1.08
Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats. Diabetologia (1993) 1.08
Perturbation of pancreatic islet function in glucose-infused rats. Metabolism (1990) 1.07
Cytochalasin B-induced impariment of glucose metabolism in islets of Langerhans. Endocrinology (1976) 1.07
Dynamics of insulin release and microtubular-microfilamentous system. VII. Do microfilaments provide the motive force for the translocation and extrusion of beta granules? Diabetes (1975) 1.07
Effects of glucose and glucagon on the fructose 2,6-bisphosphate content of pancreatic islets and purified pancreatic B-cells. A comparison with isolated hepatocytes. Biochem J (1984) 1.07
The stimulus secretion coupling of glucose-induced insulin release. XXVII. Effect of glucose on K+ fluxes in isolated islets. Pflugers Arch (1978) 1.07
Synergistic effect of a tumor-promoting phorbol ester and a hypoglycemic sulfonylurea upon insulin release. Endocrinology (1983) 1.07
The stimulus-secretion coupling of glucose-induced insulin release. Sorbitol metabolism in isolated islets. Eur J Biochem (1974) 1.07
Calcium antagonists and islet function: VII. Effect of calcium deprivation. J Membr Biol (1978) 1.07