Published in Proc Natl Acad Sci U S A on February 01, 1981
A polymer-dependent increase in phosphorylation of beta-tubulin accompanies differentiation of a mouse neuroblastoma cell line. J Cell Biol (1985) 2.35
Evidence that calcium may control neurite outgrowth by regulating the stability of actin filaments. J Cell Biol (1989) 1.04
Correlation of Ca2+-and calmodulin-dependent protein kinase activity with secretion of insulin from islets of Langerhans. Biochem J (1983) 1.04
Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive calcium channels in nerve terminal preparations. Proc Natl Acad Sci U S A (1984) 0.96
Interaction between metabotropic glutamate receptor 7 and alpha tubulin. J Neurochem (2002) 0.85
Separation of endogenous calmodulin- and cAMP-dependent kinases from microtubule preparations. Proc Natl Acad Sci U S A (1985) 0.85
The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic Paraplegias. Front Mol Neurosci (2016) 0.75
Calcium-ion and calmodulin-dependent kappa-casein kinase in rat mammary acini. Biochem J (1984) 0.75
High resolution two-dimensional electrophoresis of proteins. J Biol Chem (1975) 133.45
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
Microtubule assembly in the absence of added nucleotides. Proc Natl Acad Sci U S A (1973) 18.46
THE DEPENDENCE OF CONTRACTION AND RELAXATION OF MUSCLE FIBRES FROM THE CRAB MAIA SQUINADO ON THE INTERNAL CONCENTRATION OF FREE CALCIUM IONS. Biochim Biophys Acta (1964) 12.48
Microtubule formation in vitro in solutions containing low calcium concentrations. Science (1972) 10.60
The mechanism of action of colchicine. Binding of colchincine-3H to cellular protein. J Cell Biol (1967) 9.66
Calmodulin plays a pivotal role in cellular regulation. Science (1980) 8.20
Microtubules. Annu Rev Biochem (1973) 6.75
The role of calcium in the release of neurotransmitter substances and hormones. Pharmacol Rev (1970) 5.55
Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein. Proc Natl Acad Sci U S A (1975) 5.25
Cell communication, calcium ion, and cyclic adenosine monophosphate. Science (1970) 5.25
Relationships between calcium and cyclic nucleotides in cell activation. Physiol Rev (1977) 3.45
Control of microtubule assembly-disassembly by calcium-dependent regulator protein. Proc Natl Acad Sci U S A (1978) 3.15
Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable protein. Nature (1978) 2.06
Stimulation of Ca2+-dependent neurotransmitter release and presynaptic nerve terminal protein phosphorylation by calmodulin and a calmodulin-like protein isolated from synaptic vesicles. Proc Natl Acad Sci U S A (1979) 1.97
Isolation of postsynaptic densities from rat brain. J Cell Biol (1974) 1.77
Inhibition of microtubule assembly by phosphorylation of microtubule-associated proteins. Biochemistry (1980) 1.70
Colchicine-binding activity in particulate fractions of mouse brain. J Neurochem (1970) 1.69
Isolation and structural studies on synaptic complexes from rat brain. J Cell Biol (1972) 1.63
Muscle-like contractile proteins and tubulin in synaptosomes. Proc Natl Acad Sci U S A (1974) 1.60
Rat brain tubulin and protein kinase activity. J Biol Chem (1974) 1.36
Trophic functions of the neuron. 3. Mechanisms of neurotrophic interactions. Systems of material transport in nerve fibers (axoplasmic transport) related to nerve function and trophic control. Ann N Y Acad Sci (1974) 1.33
Immunohistochemical demonstration of tubulin associated with microtubules and synaptic junctions in mammalian brain. J Neurocytol (1975) 1.25
Endogenous protein kinase inhibitors. Purification, characterization, and distribution in different tissues. J Biol Chem (1977) 1.17
Regulation of the level of endogenous phosphorylation of specific brain proteins by diphenylhydantoin. J Neurochem (1977) 0.93
Role of calmodulin in neurotransmitter release and synaptic function. Ann N Y Acad Sci (1980) 0.92
Calcium-dependent phosphorylation of synaptic vesicle proteins and its possible role in mediating neurotransmitter release and vesicle function. Biochem Biophys Res Commun (1977) 0.92
Antagonistic action of diphenylhydantoin and calcium on the level of phosphorylation of particular rat and human brain proteins. Brain Res (1977) 0.86
Enzymatic acitivity in tubulin preparations: cyclic-AMP dependent protein kinase activity of brain microtubule protein. J Neurochem (1975) 0.86
Calcium and cAMP as interrelated intracellular messengers. Ann N Y Acad Sci (1975) 0.83
Tryptophanyl and carboxylic acid residues in the active centre of glucoamylase I from Aspergillus niger. Carbohydr Res (1976) 0.79
The calibration and use of a calcium ion-specific electrode for kinetic studies of mitochondrial calcium transport. Anal Biochem (1979) 0.77
The molecular structure of human erythrocyte spectrin. Biophysical and electron microscopic studies. J Mol Biol (1979) 5.36
Determinants of mortality in status epilepticus. Epilepsia (1994) 3.03
Prevalence of nonconvulsive status epilepticus in comatose patients. Neurology (2000) 2.86
Direct detection of nucleic acid hybridization on the surface of a charge coupled device. Nucleic Acids Res (1994) 2.38
Stimulation of Ca2+-dependent neurotransmitter release and presynaptic nerve terminal protein phosphorylation by calmodulin and a calmodulin-like protein isolated from synaptic vesicles. Proc Natl Acad Sci U S A (1979) 1.97
Glutamate oxalate transaminase (GOT) genetics in Mus musculus: linkage, polymorphism, and phenotypes of the Got-2 and Got-1 loci. Biochem Genet (1970) 1.96
Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet (1969) 1.69
Purification and characterization of a calmodulin-dependent kinase from rat brain cytosol able to phosphorylate tubulin and microtubule-associated proteins. J Biol Chem (1983) 1.69
The use of topiramate in refractory status epilepticus. Neurology (2003) 1.56
Regulation of phosphorylation of a specific protein in toad-bladder membrane by antidiuretic hormone and cyclic AMP, and its possible relationship to membrane permeability changes. Proc Natl Acad Sci U S A (1973) 1.49
Cellular actions of topiramate: blockade of kainate-evoked inward currents in cultured hippocampal neurons. Epilepsia (2000) 1.48
Identification of the major postsynaptic density protein as homologous with the major calmodulin-binding subunit of a calmodulin-dependent protein kinase. J Neurochem (1984) 1.44
Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. Eur J Pharmacol (2001) 1.29
NMDA receptor activation during status epilepticus is required for the development of epilepsy. Brain Res (1998) 1.28
Association of synapsin I with neuronal cytoskeleton. Identification in cytoskeletal preparations in vitro and immunocytochemical localization in brain of synapsin I. J Biol Chem (1986) 1.28
Glutamate injury-induced epileptogenesis in hippocampal neurons: an in vitro model of stroke-induced "epilepsy". Stroke (2001) 1.28
In whom does status epilepticus occur: age-related differences in children. Epilepsia (1997) 1.26
Calcium dependent neurotransmitter release and protein phosphorylation in synaptic vesicles. Biochem Biophys Res Commun (1978) 1.22
Pharmacokinetic-pharmacodynamic relationships of controlled-release oxycodone. Clin Pharmacol Ther (1996) 1.22
Brain injury-induced enhanced limbic epileptogenesis: anatomical and physiological parallels to an animal model of temporal lobe epilepsy. Epilepsy Res (1996) 1.18
Generation and propagation of epileptiform discharges in a combined entorhinal cortex/hippocampal slice. J Neurophysiol (1993) 1.15
Calmodulin in neurotransmitter release and synaptic function. Fed Proc (1982) 1.11
Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy. Neuroscience (2007) 1.09
Inhibition of calcium/calmodulin kinase II alpha subunit expression results in epileptiform activity in cultured hippocampal neurons. Proc Natl Acad Sci U S A (2000) 1.08
Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy. Cell Calcium (2001) 1.08
In vitro status epilepticus causes sustained elevation of intracellular calcium levels in hippocampal neurons. Brain Res (1999) 1.07
The calmodulin hypothesis of neurotransmission. Cell Calcium (1981) 1.07
The suppression of testis-brain RNA binding protein and kinesin heavy chain disrupts mRNA sorting in dendrites. J Cell Sci (1999) 1.05
Regulation of protein kinase C activity by gangliosides. J Biol Chem (1987) 1.05
Long-term alteration of calcium homeostatic mechanisms in the pilocarpine model of temporal lobe epilepsy. Brain Res (2001) 1.05
N-methyl-D-aspartate receptor activation regulates refractoriness of status epilepticus to diazepam. Neuroscience (1999) 1.05
Status epilepticus causes long-term NMDA receptor-dependent behavioral changes and cognitive deficits. Epilepsia (1998) 1.03
Prospective population-based study of intermittent and continuous convulsive status epilepticus in Richmond, Virginia. Epilepsia (1999) 1.01
CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells. Exp Cell Res (1998) 1.00
Inability to restore resting intracellular calcium levels as an early indicator of delayed neuronal cell death. Brain Res (1995) 1.00
Status epilepticus in older patients: epidemiology and treatment options. Drugs Aging (2001) 1.00
Micromolar affinity benzodiazepine receptors: identification and characterization in central nervous system. Science (1982) 0.99
Status epilepticus results in an N-methyl-D-aspartate receptor-dependent inhibition of Ca2+/calmodulin-dependent kinase II activity in the rat. Neuroscience (2000) 0.97
Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive calcium channels in nerve terminal preparations. Proc Natl Acad Sci U S A (1984) 0.96
Induction of spontaneous recurrent epileptiform discharges causes long-term changes in intracellular calcium homeostatic mechanisms. Cell Calcium (2000) 0.96
Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum. J Ethnopharmacol (2001) 0.96
Chronic DeltaFosB expression and increased AP-1 transcription factor binding are associated with the long term plasticity changes in epilepsy. Brain Res Mol Brain Res (2000) 0.95
Cadmium transport by a Cd2+-sensitive and a Cd2+-resistant strain of Bacillus subtilis. Can J Microbiol (1986) 0.95
Excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons. J Neurosci (1995) 0.95
Univariate genetic analyses of epilepsy and seizures in a population-based twin study: the Virginia Twin Registry. Genet Epidemiol (1998) 0.95
Calcium influx constitutes the ionic basis for the maintenance of glutamate-induced extended neuronal depolarization associated with hippocampal neuronal death. Cell Calcium (2003) 0.94
Calcium/ganglioside-dependent protein kinase activity in rat brain membrane. J Neurochem (1985) 0.94
Synergistic effect of status epilepticus and ischemic brain injury on mortality. Epilepsy Res (1998) 0.94
Physiological and pharmacological alterations in postsynaptic GABA(A) receptor function in a hippocampal culture model of chronic spontaneous seizures. J Neurophysiol (1997) 0.93
Regulation of the level of endogenous phosphorylation of specific brain proteins by diphenylhydantoin. J Neurochem (1977) 0.93
Pilocarpine-induced status epilepticus causes N-methyl-D-aspartate receptor-dependent inhibition of microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake. J Neurochem (2000) 0.92
Role of calmodulin in neurotransmitter release and synaptic function. Ann N Y Acad Sci (1980) 0.92
Calcium-dependent phosphorylation of synaptic vesicle proteins and its possible role in mediating neurotransmitter release and vesicle function. Biochem Biophys Res Commun (1977) 0.92
Short-term outcomes of children with febrile status epilepticus. Epilepsia (2001) 0.92
Loss of type II calcium/calmodulin-dependent kinase activity correlates with stages of development of electrographic seizures in status epilepticus in rat. Epilepsy Res (1992) 0.91
Loss of GABAA receptors during partial status epilepticus. Neurology (1994) 0.91
Calcium-dependent phosphorylation of specific synaptosomal fraction proteins: possible role of phosphoproteins in mediating neurotransmitter release. Biochem Biophys Res Commun (1976) 0.91
Long-lasting reduction of inhibitory function and gamma-aminobutyric acid type A receptor subunit mRNA expression in a model of temporal lobe epilepsy. Proc Natl Acad Sci U S A (1996) 0.91
Prognostic value of EEG monitoring after status epilepticus: a prospective adult study. J Clin Neurophysiol (1997) 0.91
Long-duration self-sustained epileptiform activity in the hippocampal-parahippocampal slice: a model of status epilepticus. J Neurophysiol (1995) 0.91
Estimating the economic burden of status epilepticus to the health care system. Seizure (2005) 0.90
The occurrence of epilepsy and febrile seizures in Virginian and Norwegian twins. Neurology (1991) 0.90
Chronic inhibition of Ca(2+)/calmodulin kinase II activity in the pilocarpine model of epilepsy. Brain Res (2000) 0.89
Hemodynamic monitoring prior to and at the time of death in status epilepticus. Epilepsy Res (1998) 0.89
Electrophysiology of glutamate neurotoxicity in vitro: induction of a calcium-dependent extended neuronal depolarization. J Neurophysiol (1992) 0.89
Long-lasting decrease in neuronal Ca2+/calmodulin-dependent protein kinase II activity in a hippocampal neuronal culture model of spontaneous recurrent seizures. Brain Res (1999) 0.87
Neurotoxic activation of glutamate receptors induces an extended neuronal depolarization in cultured hippocampal neurons. Brain Res (1991) 0.87
Dissection of the human erythrocyte spectrin molecule using monoclonal antibodies. EMBO J (1982) 0.87
Analysis of electrocardiographic changes in status epilepticus. Epilepsy Res (1993) 0.87
Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils. Stroke (1990) 0.86
Antagonistic action of diphenylhydantoin and calcium on the level of phosphorylation of particular rat and human brain proteins. Brain Res (1977) 0.86
Ca2+ and calmodulin-dependent phosphorylation of endogenous synaptic vesicle tubulin by a vesicle-bound calmodulin kinase system. J Neurochem (1982) 0.86
Basic mechanisms of status epilepticus. Adv Neurol (1999) 0.85
Separation of endogenous calmodulin- and cAMP-dependent kinases from microtubule preparations. Proc Natl Acad Sci U S A (1985) 0.85
Persistent increased DNA-binding and expression of serum response factor occur with epilepsy-associated long-term plasticity changes. J Neurosci (1999) 0.85
Phosphorylation of neurofilament proteins by endogenous calcium/calmodulin-dependent protein kinase. Biochem Biophys Res Commun (1985) 0.85
Regulation of protein phosphorylation and sodium transport in toad bladder. J Gen Physiol (1975) 0.84
Inhibition of Ca2+ conductance in identified leech neurons by benzodiazepines. Proc Natl Acad Sci U S A (1985) 0.84
Anticonvulsant effect of FS-1 subfraction isolated from roots of Delphinim denudatum on hippocampal pyramidal neurons. Phytother Res (2003) 0.84
Hippocampal neurons exhibit both persistent Ca2+ influx and impairment of Ca2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure. Brain Res (2001) 0.84
Tubulin-associated calmodulin-dependent kinase: evidence for an endogenous complex of tubulin with a calcium-calmodulin-dependent kinase. J Neurochem (1984) 0.83
Use of intramuscular midazolam for status epilepticus. J Emerg Med (1999) 0.83
Possible role of calcium-dependent protein phosphorylation in mediating neurotransmitter release and anticonvulsant action. Epilepsia (1977) 0.83
Carboxylmethylation of calmodulin inhibits calmodulin-dependent phosphorylation in rat brain membranes and cytosol. J Biol Chem (1983) 0.83
Modulation of GABAergic receptor binding by activation of calcium and calmodulin-dependent kinase II membrane phosphorylation. Brain Res (1998) 0.83
Conditions for pharmacologic evaluation in the gerbil model of forebrain ischemia. Stroke (1989) 0.82
Kindling induces a long-lasting change in the activity of a hippocampal membrane calmodulin-dependent protein kinase system. Brain Res (1986) 0.81
Global forebrain ischemia results in decreased immunoreactivity of calcium/calmodulin-dependent protein kinase II. J Cereb Blood Flow Metab (1992) 0.81
Chronic inhibition of cortex microsomal Mg(2+)/Ca(2+) ATPase-mediated Ca(2+) uptake in the rat pilocarpine model following epileptogenesis. J Neurochem (2001) 0.81
Effect of D, alpha-tocopheryl succinate and polyethylene glycol on performance tests after fluid percussion brain injury. J Neurotrauma (1989) 0.81
Evidence for a genetic predisposition for status epilepticus. Neurology (1998) 0.81
Kindling produces long-lasting and selective changes in gene expression of hippocampal neurons. Proc Natl Acad Sci U S A (1993) 0.81
GABAA alpha 2 mRNA levels are decreased following induction of spontaneous epileptiform discharges in hippocampal-entorhinal cortical slices. Brain Res (1996) 0.81
Benzodiazepine inhibition of the calcium-calmodulin protein kinase system in brain membrane. Science (1981) 0.81
Multiport-readout frame-transfer 5 megapixel CCD imaging system for TEM applications. Ultramicroscopy (2000) 0.80
Phenytoin protects against ischemia-produced neuronal cell death. Brain Res (1989) 0.80
Excitotoxicity affects membrane potential and calmodulin kinase II activity in cultured rat cortical neurons. Stroke (1993) 0.80
Identification of endogenous calmodulin-dependent kinase and calmodulin-binding proteins in cold-stable microtubule preparations from rat brain. J Neurochem (1985) 0.80
Gangliosides inhibit phospholipid-sensitive Ca2+-dependent kinase phosphorylation of rat myelin basic proteins. J Neurosci Res (1986) 0.80