Published in Biochem Biophys Res Commun on April 30, 1981
Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex. Proc Natl Acad Sci U S A (1983) 4.83
Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor. Proc Natl Acad Sci U S A (1981) 1.87
Modulation of the epidermal growth factor receptor by platelet-derived growth factor and choleragen: effects on mitogenesis. Proc Natl Acad Sci U S A (1982) 1.16
Human T cell activation. IV. T cell activation and proliferation via the early activation antigen EA 1. J Exp Med (1989) 0.95
Antibody mimicking the action of RAS proteins on yeast adenylyl cyclase: implication for RAS-effector interaction. Mol Cell Biol (1993) 0.88
Monoclonal antibodies to the beta-adrenergic receptor: modulation of catecholamine-sensitive adenylate cyclase by the antibody. Arch Dermatol Res (1986) 0.85
Monoclonal antibodies to purified muscarinic receptor display agonist-like activity. Proc Natl Acad Sci U S A (1984) 0.77
Levels of autoantibodies against beta-adrenergic receptors and mitochondrial antigens in sera of cardiomyopathic patients estimated by ELISA method. Basic Res Cardiol (1992) 0.75
Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB J (2005) 5.46
Molecular characterization of the human beta 3-adrenergic receptor. Science (1989) 4.13
A leptin missense mutation associated with hypogonadism and morbid obesity. Nat Genet (1998) 2.68
Tissue distribution of beta 3-adrenergic receptor mRNA in man. J Clin Invest (1993) 2.16
Lymphocyte migration through brain endothelial cell monolayers involves signaling through endothelial ICAM-1 via a rho-dependent pathway. J Immunol (1999) 2.03
Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N Engl J Med (1995) 1.99
ICAM-1-coupled cytoskeletal rearrangements and transendothelial lymphocyte migration involve intracellular calcium signaling in brain endothelial cell lines. J Immunol (2000) 1.92
Role of transforming growth factor beta type II receptor in hepatic fibrosis: studies of human chronic hepatitis C and experimental fibrosis in rats. Hepatology (1999) 1.90
Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity. N Engl J Med (1995) 1.88
Complete amino acid sequence and maturation of the mouse submaxillary gland renin precursor. Nature (1982) 1.83
Anti-alprenolol anti-idiotypic antibodies bind to beta-adrenergic receptors and modulate catecholamine-sensitive adenylate cyclase. Proc Natl Acad Sci U S A (1980) 1.80
A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans. Nat Genet (2001) 1.79
A rabbit with the allotypic phenotype: ala2a3 b4b5b6. J Immunol (1974) 1.77
The human beta 3-adrenoceptor: the search for a physiological function. Trends Pharmacol Sci (1994) 1.76
Chemokines control fat accumulation and leptin secretion by cultured human adipocytes. Mol Cell Endocrinol (2001) 1.75
Internalization of beta-adrenergic receptor in A431 cells involves non-coated vesicles. Eur J Cell Biol (1989) 1.71
Molecular characterization of the mouse beta 3-adrenergic receptor: relationship with the atypical receptor of adipocytes. EMBO J (1991) 1.65
Structure of the gene for human beta 2-adrenergic receptor: expression and promoter characterization. Proc Natl Acad Sci U S A (1987) 1.62
ICAM-1 signaling pathways associated with Rho activation in microvascular brain endothelial cells. J Immunol (1998) 1.56
Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells. J Cell Physiol (1994) 1.55
Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells. J Biol Chem (1994) 1.46
Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy. J Clin Invest (1990) 1.44
Evidence for reversible microclustering of lentil lectin membrane receptors on HeLa cells. FEBS Lett (1980) 1.34
Mrp1 multidrug resistance-associated protein and P-glycoprotein expression in rat brain microvessel endothelial cells. J Neurochem (1998) 1.31
The human beta 3-adrenergic receptor is resistant to short term agonist-promoted desensitization. Mol Pharmacol (1993) 1.31
Activation of ErbB2 receptor tyrosine kinase supports invasion of endothelial cells by Neisseria meningitidis. J Cell Biol (2001) 1.29
Evidence for a functional beta 3-adrenoceptor in man. Br J Pharmacol (1993) 1.27
The human carcinoma cell line A431 possesses large numbers of functional beta-adrenergic receptors. FEBS Lett (1984) 1.25
BBB on chip: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function. Biomed Microdevices (2013) 1.24
Comparison of the N-terminal sequences of aspartate and ornithine carbamoyltransferases of Escherichia coli. FEBS Lett (1977) 1.23
Angiotensin II type 2 receptors mediate inhibition of mitogen-activated protein kinase cascade and functional activation of SHP-1 tyrosine phosphatase. Biochem J (1997) 1.22
Nitric oxide and endothelin secretion by brain microvessel endothelial cells: regulation by cyclic nucleotides. J Cell Physiol (1993) 1.20
Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats. Proc Natl Acad Sci U S A (2001) 1.20
Atypical beta-adrenergic receptor in 3T3-F442A adipocytes. Pharmacological and molecular relationship with the human beta 3-adrenergic receptor. J Biol Chem (1991) 1.19
Genetic variation in the stress protein hsp70-2 gene is highly associated with obesity. Int J Obes Relat Metab Disord (2001) 1.17
Extensive sequence homologies among lectins from leguminous plants. Biochem Biophys Res Commun (1977) 1.17
Structural and conformational features determining selective signal transduction in the beta 3-adrenergic receptor. Mol Pharmacol (1993) 1.17
Hydroxyurea downregulates endothelin-1 gene expression and upregulates ICAM-1 gene expression in cultured human endothelial cells. Pharmacogenomics J (2003) 1.17
Leptin receptor gene variation and obesity: lack of association in a white British male population. Hum Mol Genet (1997) 1.16
Mediation of most atypical effects by species homologues of the beta 3-adrenoceptor. Br J Pharmacol (1994) 1.15
Molecular characterization of salt-stress-associated protein in citrus: protein and cDNA sequence homology to mammalian glutathione peroxidases. Plant Mol Biol (1993) 1.15
Beta-3 adrenoceptor selectivity of the dioxolane dicarboxylate phenethanolamines. J Pharmacol Exp Ther (1994) 1.14
Isolation of adenylate cyclase-free, beta-adrenergic receptor from turkey erythrocyte membranes by affinity chromatography. Proc Natl Acad Sci U S A (1977) 1.13
Characterization, serological specificity, and diagnostic possibilities of monoclonal antibodies against Legionella pneumophila. J Clin Microbiol (1983) 1.12
Substituting selenocysteine for catalytic cysteine 41 enhances enzymatic activity of plant phospholipid hydroperoxide glutathione peroxidase expressed in Escherichia coli. J Biol Chem (2000) 1.12
beta-Adrenergic agonist activity of a monoclonal anti-idiotypic antibody. Proc Natl Acad Sci U S A (1985) 1.11
Evidence for essential disulfide bonds in beta1-adrenergic receptors of turkey erythrocyte membranes. Inactivation by dithiothreitol. J Biol Chem (1979) 1.10
Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins. Mol Endocrinol (1999) 1.09
The production and characterization of antibodies against beta-adrenergic antagonists. Biochem Pharmacol (1978) 1.09
Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls. FASEB J (2009) 1.08
Mutation analysis of the 8p22 candidate tumor suppressor gene ATIP/MTUS1 in hepatocellular carcinoma. Mol Cell Endocrinol (2006) 1.08
Functional expression of the human serotonin 5-HT1A receptor in Escherichia coli. Ligand binding properties and interaction with recombinant G protein alpha-subunits. J Biol Chem (1992) 1.08
Antigenic analysis of the second extra-cellular loop of the human beta-adrenergic receptors. Clin Exp Immunol (1989) 1.07
Redistribution of muscarinic acetylcholine receptors on human fibroblasts induced by regulatory ligands. Biol Cell (1987) 1.06
Differential signaling of human Mel1a and Mel1b melatonin receptors through the cyclic guanosine 3'-5'-monophosphate pathway. Biochem Pharmacol (1999) 1.06
Expression of three human beta-adrenergic-receptor subtypes in transfected Chinese hamster ovary cells. Eur J Biochem (1991) 1.05
Human beta 2-adrenergic receptors expressed in Escherichia coli membranes retain their pharmacological properties. Proc Natl Acad Sci U S A (1988) 1.05
Effector-dependent conformational changes in protein kinase C gamma through epitope mapping with inhibitory monoclonal antibodies. Eur J Biochem (1990) 1.05
New molecular and structural determinants involved in beta 2-adrenergic receptor desensitization and sequestration. Delineation using chimeric beta 3/beta 2-adrenergic receptors. J Biol Chem (1996) 1.04
The leptin receptor promoter controls expression of a second distinct protein. Nucleic Acids Res (1997) 1.04
Localisation of three epitopes of the env protein of feline immunodeficiency virus. Mol Immunol (1992) 1.03
Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation. Mol Pharmacol (1999) 1.03
Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. J Biol Chem (1999) 1.02
Interactions between brain endothelial cells and human T-cell leukemia virus type 1-infected lymphocytes: mechanisms of viral entry into the central nervous system. J Virol (2000) 0.99
Circulating endothelial progenitor cells in systemic sclerosis: association with disease severity. Ann Rheum Dis (2008) 0.99
Restricted rabbit antibodies: amino acid sequences of rabbit H chains of allotype a1, a2, and a3 in the region 80 to 94. J Immunol (1973) 0.99
Changes in intrinsic circular dichroism of several homogeneous anti-type 3 pneumococcal antibodies on binding of a small hapten. Proc Natl Acad Sci U S A (1972) 0.99
In vitro degradation of the C-terminal octapeptide of cholecystokinin by 'enkephalinase A'. FEBS Lett (1983) 0.99
Differential regulation of beta 1- and beta 2-adrenergic receptor protein and mRNA levels by glucocorticoids during 3T3-F442A adipose differentiation. J Biol Chem (1990) 0.99
The biochemical effect of the naturally occurring Trp64-->Arg mutation on human beta3-adrenoceptor activity. Eur J Biochem (1997) 0.98
Anti-idiotype and anti-hormone receptor antibodies. Springer Semin Immunopathol (1983) 0.98
Expression of two human beta-adrenergic receptors in Escherichia coli: functional interaction with two forms of the stimulatory G protein. Proc Natl Acad Sci U S A (1991) 0.98
Common ancestor for concanavalin A and lentil lectin? Proc Natl Acad Sci U S A (1978) 0.98
The amino-terminal sequence of the 40,000 molecular weight subunit of the acetylcholine receptor protein from Torpedo marmorata. FEBS Lett (1979) 0.98
Serological diagnosis of feline immunodeficiency virus infection based on synthetic peptides from Env glycoproteins. Res Virol (1993) 0.97
Purification of muscarinic acetylcholine receptors by affinity chromatography. EMBO J (1983) 0.97
Beta-adrenergic receptor-dependent and -independent stimulation of adenylate cyclase is impaired during severe sepsis in humans. Intensive Care Med (1998) 0.97
Structural basis for functional diversity of beta 1-, beta 2- and beta 3-adrenergic receptors. Biochem Pharmacol (1991) 0.96
F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: effects of cyclic AMP and astrocytic factors. Brain Res (1997) 0.96
Transformation by simian virus 40 of spleen cells from a hyperimmune rabbit: evidence for synthesis of immunoglobulin by the transformed cells. Proc Natl Acad Sci U S A (1974) 0.95
Multiple amino acid substitutions between murine gamma 2a heavy chain Fc regions of Ig1a and Ig1b allotypic forms. Proc Natl Acad Sci U S A (1981) 0.95
Cellular signaling by an agonist-activated receptor/Gs alpha fusion protein. Proc Natl Acad Sci U S A (1994) 0.95
Dimerization-driven interaction of hepatitis C virus core protein with NS3 helicase. J Gen Virol (2010) 0.94
Porcine follitropin. The amino-acid sequence of the beta subunit. Eur J Biochem (1978) 0.94