Published in Proc Natl Acad Sci U S A on August 01, 1982
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A strain of Fujinami sarcoma virus which is temperature-sensitive in protein phosphorylation and cellular transformation. Cell (1980) 2.61
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Two distinct candidate transforming genes of lymphoid leukosis virus-induced neoplasms. Nature (1981) 2.03
A cellular protein is immunologically crossreactive with and functionally homologous to the Fujinami sarcoma virus transforming protein. Cell (1982) 1.86
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Characterization of a 105,000 molecular weight gag-related phosphoprotein from cells transformed by the defective avian sarcoma virus PRCII. Virology (1981) 1.67
Mutants of Fujinami sarcoma virus which are temperature sensitive for cellular transformation and protein kinase activity. J Virol (1981) 1.67
Some biological properties of two new avian sarcoma viruses. J Virol (1981) 1.57
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Structure of the provirus within NIH 3T3 cells transfected with Harvey sarcoma virus DNA. J Virol (1981) 1.27
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Cleavage of four avian sarcoma virus polyproteins with virion protease p15 removes gag sequences and yields large fragments that function as tyrosine phosphoacceptors in vitro. Proc Natl Acad Sci U S A (1981) 0.94
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature (1981) 17.31
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci U S A (1999) 11.38
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol (2000) 9.85
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The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant. Virology (1971) 7.83
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell (1983) 7.37
Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal Biochem (1993) 6.78
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation. Mol Cell Biol (1984) 6.40
A novel viral oncogene with structural similarity to phospholipase C. Nature (1988) 5.84
Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet (1983) 5.64
Rapid transformation of cells by Rous sarcoma virus. Proc Natl Acad Sci U S A (1969) 5.27
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol Cell Biol (1994) 5.02
Size and genetic content of viral RNAs in avian oncovirus-infected cells. J Virol (1977) 5.00
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A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group. N Engl J Med (2000) 4.73
Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase. Nature (2001) 4.73
An avian oncovirus mutant (SE 21Q1b) deficient in genomic RNA: biological and biochemical characterization. Cell (1978) 4.66
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol (2000) 4.64
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Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature (1992) 4.46
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Nucleotide sequence of Fujinami sarcoma virus: evolutionary relationship of its transforming gene with transforming genes of other sarcoma viruses. Cell (1982) 4.06
An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins. Nature (1985) 4.06
Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein. Science (1985) 3.97
Structural insights into the evolution of an antibody combining site. Science (1997) 3.92
Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: relevance for autoimmunity. Lancet (1983) 3.85
Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell (1999) 3.84
Characterization of protein kinase activity associated with the transforming gene product of Fujinami sarcoma virus. Cell (1980) 3.82
Location of envelope-specific and sarcoma-specific oligonucleotides on RNA of Schmidt-Ruppin Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.73
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1984) 3.70
Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science (1990) 3.67
Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein. Proc Natl Acad Sci U S A (1979) 3.66
Proteins of helper-dependent RSV. Virology (1971) 3.62
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The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence. Cell (1992) 3.59
Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein. Cell (1987) 3.50
Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21. Nature (1992) 3.48
Local mutagenesis of Rous sarcoma virus: the major sites of tyrosine and serine phosphorylation of pp60src are dispensable for transformation. Cell (1983) 3.46
Bacterial proteins required for replication of phage Q ribonucleic acid. Pruification and properties of host factor I, a ribonucleic acid-binding protein. J Biol Chem (1972) 3.45
A cell-associated factor essential for formation of an infectious form of Rous sarcoma virus. Proc Natl Acad Sci U S A (1970) 3.43
Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src. Mol Cell Biol (1985) 3.39
Recombination between viral and cellular sequences generates transforming sarcoma virus. Proc Natl Acad Sci U S A (1978) 3.38
Isolation of defective mutant of avian sarcoma virus. Proc Natl Acad Sci U S A (1973) 3.38
Activation of the c-myc gene by translocation: a model for translational control. Proc Natl Acad Sci U S A (1983) 3.36
DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. J Virol (1982) 3.35
Neuronal pp60c-src contains a six-amino acid insertion relative to its non-neuronal counterpart. Science (1987) 3.35
Combinatorial control of the specificity of protein tyrosine phosphatases. Curr Opin Cell Biol (2001) 3.30
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Detection of avian tumor virus RNA in uninfected chicken embryo cells. J Virol (1973) 2.85
Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein. Mol Cell Biol (1986) 2.84
Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase. Nat Genet (1999) 2.81
Association of the polyomavirus middle-T antigen with c-yes protein. Nature (1987) 2.78
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem (1996) 2.77
Activation of the transforming potential of p60c-src by a single amino acid change. Proc Natl Acad Sci U S A (1986) 2.70
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Characterization of the transforming gene of Fujinami sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.68
Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients. J Clin Invest (1993) 2.64
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Mol Cell (1999) 2.64
A type of chick embryo cell that fails to support formation of infectious RSV. Virology (1970) 2.63
Fine structural mapping of a critical NH2-terminal region of p60src. Proc Natl Acad Sci U S A (1985) 2.53
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BRCA1 regulates p53-dependent gene expression. Proc Natl Acad Sci U S A (1998) 2.50
Homology exists among the transforming sequences of avian and feline sarcoma viruses. Proc Natl Acad Sci U S A (1980) 2.50
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development. Cell (1995) 2.49
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Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity. Diabetes (1999) 2.47