Published in Nucleic Acids Res on March 25, 1982
Selection of AUG initiation codons differs in plants and animals. EMBO J (1987) 12.73
The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA. Nucleic Acids Res (1985) 12.11
Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol Cell Biol (1984) 3.25
An improved strategy for rapid direct sequencing of both strands of long DNA molecules cloned in a plasmid. Nucleic Acids Res (1983) 3.02
Upstream regulatory elements are necessary and sufficient for transcription of a U6 RNA gene by RNA polymerase III. EMBO J (1988) 2.91
Nucleotide sequence of noncoding regions in Rous-associated virus-2: comparisons delineate conserved regions important in replication and oncogenesis. J Virol (1984) 2.71
Cloning, nucleotide sequence, and expression of the Bacillus cereus 5/B/6 beta-lactamase II structural gene. J Bacteriol (1988) 2.55
Nucleotide sequence of the Escherichia coli motB gene and site-limited incorporation of its product into the cytoplasmic membrane. J Bacteriol (1986) 2.51
Cloning and nucleotide sequence of the tzs gene from Agrobacterium tumefaciens strain T37. Nucleic Acids Res (1985) 2.25
Site-specific DNA binding of nuclear factor I: analyses of cellular binding sites. Mol Cell Biol (1985) 2.19
Sequence specificity of exonuclease III from E. coli. Nucleic Acids Res (1982) 2.17
Identification of Escherichia coli region III flagellar gene products and description of two new flagellar genes. J Bacteriol (1984) 1.99
Localization of a poliovirus type 1 neutralization epitope in viral capsid polypeptide VP1. Proc Natl Acad Sci U S A (1983) 1.94
Deletion loop mutagenesis: a novel method for the construction of point mutations using deletion mutants. Nucleic Acids Res (1982) 1.90
The FLP recombinase of the Saccharomyces cerevisiae 2 microns plasmid attaches covalently to DNA via a phosphotyrosyl linkage. Mol Cell Biol (1985) 1.77
A poliovirus type 1 neutralization epitope is located within amino acid residues 93 to 104 of viral capsid polypeptide VP1. EMBO J (1983) 1.59
Identification and temperature regulation of Legionella pneumophila genes involved in type IV pilus biogenesis and type II protein secretion. Infect Immun (1998) 1.51
Localization of the hsp83 transcript within a 3292 nucleotide sequence from the 63B heat shock locus of D. melanogaster. Nucleic Acids Res (1983) 1.50
Adenovirus origin of DNA replication: sequence requirements for replication in vitro. Mol Cell Biol (1987) 1.44
Formation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coli. Nucleic Acids Res (1983) 1.26
Molecular cloning of human terminal deoxynucleotidyltransferase. Proc Natl Acad Sci U S A (1984) 1.24
Phenotypic expression in Escherichia coli and nucleotide sequence of two Chinese hamster lung cell cDNAs encoding different dihydrofolate reductases. Mol Cell Biol (1984) 1.21
Human antibodies react with an epitope of the human papillomavirus type 6b L1 open reading frame which is distinct from the type-common epitope. J Virol (1989) 1.20
Domains of beta-tubulin essential for conserved functions in vivo. Mol Cell Biol (1987) 1.10
Characterization of a tumor necrosis factor-responsive element which down-regulates the human osteocalcin gene. Mol Cell Biol (1993) 1.08
The transit peptide of a chloroplast thylakoid membrane protein is functionally equivalent to a stromal-targeting sequence. EMBO J (1989) 1.01
Enzymatic techniques for the isolation of random single-base substitutions in vitro at high frequency. Proc Natl Acad Sci U S A (1984) 0.97
Isolation and characterization of two alleles of the chicken cytochrome c gene. Nucleic Acids Res (1983) 0.97
Chromosomal rearrangements associated with LINE elements in the mouse genome. Nucleic Acids Res (1985) 0.96
ExoMeth sequencing of DNA: eliminating the need for subcloning and oligonucleotide primers. Proc Natl Acad Sci U S A (1989) 0.94
Exoquence DNA sequencing. Nucleic Acids Res (1993) 0.89
Exonuclease III protection assay with FRET probe for detecting DNA-binding proteins. Nucleic Acids Res (2005) 0.89
Site-specific nicking within the adenovirus inverted terminal repetition. Nucleic Acids Res (1984) 0.81
Characterization of a silencer element in the first exon of the human osteocalcin gene. Nucleic Acids Res (1995) 0.75
Fusion of adenovirus E1A to the glucocorticoid receptor by high-resolution deletion cloning creates a hormonally inducible viral transactivator. Mol Cell Biol (1989) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res (1979) 214.95
Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene (1977) 114.87
A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase. J Mol Biol (1975) 90.35
A system for shotgun DNA sequencing. Nucleic Acids Res (1981) 52.99
Complete nucleotide sequence of the Escherichia coli plasmid pBR322. Cold Spring Harb Symp Quant Biol (1979) 43.48
Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o. Proc Natl Acad Sci U S A (1977) 10.64
A fast and simple method for sequencing DNA cloned in the single-stranded bacteriophage M13. J Mol Biol (1979) 7.73
A DEOXYRIBONUCLEIC ACID PHOSPHATASE-EXONUCLEASE FROM ESCHERICHIA COLI. II. CHARACTERIZATION OF THE EXONUCLEASE ACTIVITY. J Biol Chem (1964) 6.72
pUR222, a vector for cloning and rapid chemical sequencing of DNA. Nucleic Acids Res (1981) 6.55
Nucleotide sequence analysis of DNA. II. Complete nucleotide sequence of the cohesive ends of bacteriophage lambda DNA. J Mol Biol (1971) 5.80
An exonuclease induced by bacteriophage lambda. I. Preparation of the crystalline enzyme. J Biol Chem (1967) 5.46
A rapid enzymatic DNA sequencing technique: determination of sequence alterations in early simian virus 40 temperature sensitive and deletion mutants. Nucleic Acids Res (1980) 2.65
Nucleotide sequence analysis of DNA. XII. The chemical synthesis and sequence analysis of a dodecadeoxynucleotide which binds to the endolysin gene of bacteriophage lambda. Biochem Biophys Res Commun (1973) 2.63
The use of exonuclease III for preparing single stranded DNA for use as a template in the chain terminator sequencing method. Nucleic Acids Res (1979) 2.51
Synchronous digestion of SV40 DNA by exonuclease III. Biochemistry (1976) 2.21
Synthetic adaptors for cloning DNA. Methods Enzymol (1979) 2.14
Sequences from the beginning of the fiber messenger RNA of adenovirus-2. J Mol Biol (1979) 1.46
Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynucleotidyl transferase. Nucleic Acids Res (1976) 23.88
DNA sequence analysis: a general, simple and rapid method for sequencing large oligodeoxyribonucleotide fragments by mapping. Nucleic Acids Res (1974) 19.42
Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides. Nucleic Acids Res (1977) 8.92
Elution of DNA from agarose gels after electrophoresis. Methods Enzymol (1979) 8.36
Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res (1985) 7.67
Nucleotide sequence analysis of DNA. II. Complete nucleotide sequence of the cohesive ends of bacteriophage lambda DNA. J Mol Biol (1971) 5.80
Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynucleotidyl transferase. Nucleic Acids Res (1976) 5.73
BK virus DNA: complete nucleotide sequence of a human tumor virus. Science (1979) 5.61
Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae. Nature (1980) 5.12
Portable microcomputer software for nucleotide sequence analysis. Nucleic Acids Res (1982) 4.72
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res (1997) 4.32
Insertion of a genetic marker into the ribosomal DNA of yeast. Plasmid (1979) 4.20
Exonuclease III: use for DNA sequence analysis and in specific deletions of nucleotides. Methods Enzymol (1983) 3.65
A reliable mapping method for sequence determination of oligodeoxyribonucleotides by mobility shift analysis. Anal Biochem (1976) 3.56
An improved procedure for utilizing terminal transferase to add homopolymers to the 3' termini of DNA. Nucleic Acids Res (1981) 3.53
Terminal transferase-catalyzed addition of nucleotides to the 3' termini of DNA. Methods Enzymol (1980) 3.44
Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing. J Cell Biol (2001) 3.35
Carbohydrate-deficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy. J Clin Invest (1998) 3.32
An improved strategy for rapid direct sequencing of both strands of long DNA molecules cloned in a plasmid. Nucleic Acids Res (1983) 3.02
A general method for inserting specific DNA sequences into cloning vehicles. Gene (1976) 3.02
Isolation of an efficient actin promoter for use in rice transformation. Plant Cell (1990) 2.94
Incidence and risk factors for side effects of spinal anesthesia. Anesthesiology (1992) 2.94
Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line. Am J Respir Cell Mol Biol (1997) 2.89
Chemical synthesis and sequence studies of deoxyribooligonucleotides which constitute the duplex sequence of the lactose operator of Escherichia coli. J Biol Chem (1975) 2.79
Role of the calcium-independent transient outward current I(to1) in shaping action potential morphology and duration. Circ Res (2000) 2.75
Nucleotide sequence analysis of DNA. XII. The chemical synthesis and sequence analysis of a dodecadeoxynucleotide which binds to the endolysin gene of bacteriophage lambda. Biochem Biophys Res Commun (1973) 2.63
Cloned synthetic lac operator DNA is biologically active. Nature (1976) 2.59
Sequence analysis of short DNA fragments. Methods Enzymol (1980) 2.56
Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression. Am J Respir Crit Care Med (2001) 2.53
IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival. Science (1998) 2.46
Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor. Development (2001) 2.43
Terminal transferase: use of the tailing of DNA and for in vitro mutagenesis. Methods Enzymol (1983) 2.36
Molecular genetic evidence supporting the clonality and appendiceal origin of Pseudomyxoma peritonei in women. Am J Pathol (1999) 2.34
The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis (2009) 2.29
Rice chloroplast DNA molecules are heterogeneous as revealed by DNA sequences of a cluster of genes. Nucleic Acids Res (1987) 2.25
Mapping the 5'-terminal nucleotides of the DNA of bacteriophage lambda and related phages. Proc Natl Acad Sci U S A (1967) 2.23
Differential regulation of airway mucin gene expression and mucin secretion by extracellular nucleotide triphosphates. Am J Respir Cell Mol Biol (2001) 2.22
Synchronous digestion of SV40 DNA by exonuclease III. Biochemistry (1976) 2.21
Rice alcohol dehydrogenase genes: anaerobic induction, organ specific expression and characterization of cDNA clones. Plant Mol Biol (1989) 2.20
The growth of cells in serum-free hormone-supplemented media. Methods Enzymol (1979) 2.18
Hybridization with synthetic oligonucleotides. Methods Enzymol (1979) 2.17
Synthetic adaptors for cloning DNA. Methods Enzymol (1979) 2.14
Nucleotide sequence analysis of bacteriophage DNA. Methods Enzymol (1974) 2.14
Microsatellite instability and the clinicopathological features of sporadic colorectal cancer. Gut (2001) 2.08
Nucleotide sequence analysis of DNA. Nat New Biol (1972) 2.07
Nucleotide sequence analysis of DNA. IX. Use of oligonucleotides of defined sequence as primers in DNA sequence analysis. Biochem Biophys Res Commun (1972) 2.04
Minimal length of the lactose operator sequence for the specific recognition by the lactose repressor. Proc Natl Acad Sci U S A (1977) 1.95
Complete nucleotide sequence of the cohesive ends of bacteriophage P2 deoxyribonucleic acid. J Biol Chem (1974) 1.94
MR nerve imaging in a prospective cohort of patients with suspected carpal tunnel syndrome. Neurology (2002) 1.94
Gender-related differences in the characteristics of problem gamblers using a gambling helpline. Am J Psychiatry (2001) 1.93
DNA sequence of a mutation in the leader region of the yeast iso-1-cytochrome c mRNA. Cell (1981) 1.92
Nucleotide sequence analysis of DNA. IV. Complete nucleotide sequence of the left-hand cohesive end of coliphage 186 DNA. J Mol Biol (1972) 1.88
Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis. Am Rev Respir Dis (1985) 1.87
Nucleotide sequence analysis of DNA. I. Partial sequence of the cohesive ends of bacteriophage lambda and 186 DNA. J Mol Biol (1970) 1.86
Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection. Genomics (1998) 1.84
Isolation and structure of a rat cytochrome c gene. J Biol Chem (1981) 1.81
Changes in pulmonary function test results after 1 year of therapy as predictors of survival in patients with idiopathic pulmonary fibrosis. Chest (1995) 1.78
Can physicians be induced to resume obstetric practice? J Am Board Fam Pract (1992) 1.78
Nonallelic members of the cytochrome c multigene family of the rat may arise through different messenger RNAs. Cell (1983) 1.76
Structure and base sequence in the cohesive ends of bacteriophage lambda DNA. J Mol Biol (1968) 1.76
RNA polymerase pausing and transcript release at the lambda tR1 terminator in vitro. J Biol Chem (1983) 1.71
Expression of a foreign gene linked to either a plant-virus or a Drosophila promoter, after electroporation of protoplasts of rice, wheat, and sorghum. Proc Natl Acad Sci U S A (1986) 1.70
Analysis of rice Act1 5' region activity in transgenic rice plants. Plant Cell (1991) 1.70
High-velocity microprojectiles for delivering nucleic acids into living cells. 1987. Biotechnology (1992) 1.69
Global analysis of gene expression in invasion by a lung cancer model. Cancer Res (2001) 1.65
Synthesis of human insulin gene. VIII. Construction of expression vectors for fused proinsulin production in Escherichia coli. Gene (1984) 1.64
BK virus DNA sequence coding for the amino-terminus of the T-antigen. Virology (1979) 1.62
Interaction of a gibberellin-induced factor with the upstream region of an alpha-amylase gene in rice aleurone tissue. Proc Natl Acad Sci U S A (1988) 1.58
Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region. Am J Respir Cell Mol Biol (2001) 1.56
Nucleotide sequence analysis of deoxyribonucleic acid. VII. Characterization of Escherichia coli exonuclease 3 activity for possible use in terminal nucleotide sequence analysis of duplex deoxyribonucleic acid. J Biol Chem (1972) 1.56
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes. Diabetologia (2012) 1.55
Comparative study of papovavirus DNA: BKV(MM), BKV(WT) and SV40. Nucleic Acids Res (1979) 1.55
Cytochrome oxidase subunit II gene of rice has an insertion sequence within the intron. Nucleic Acids Res (1984) 1.53
Synthesis of the human insulin gene. Part III. Chemical synthesis of 5'-phosphomonoester group containing deoxyribooligonucleotides by the modified phosphotriester method. Its application in the synthesis of seventeen fragments constituting human insulin C-chain DNA. Nucleic Acids Res (1980) 1.53
A biphasic chamber system for maintaining polarity of differentiation of cultured respiratory tract epithelial cells. In Vitro Cell Dev Biol (1988) 1.50
Nucleotide sequence analysis of DNA. XI. The 3' terminal sequences of bacteriophage lambda and phi 80 DNA. Biochem Biophys Res Commun (1973) 1.50
Construction of expression vectors based on the rice actin 1 (Act1) 5' region for use in monocot transformation. Mol Gen Genet (1991) 1.49
Nucleotide recognition sequence at the cleavage site of Haemophilus aegyptius II (Hae II) restriction endonuclease. Biochem Biophys Res Commun (1976) 1.48
Chemical and enzymatic synthesis of lactose operator of Escherichia coli and its binding to lactose repressor. Proc Natl Acad Sci U S A (1976) 1.48
Risk factors for subclinical atherosclerosis in a prospective cohort of patients with systemic lupus erythematosus. Ann Rheum Dis (2003) 1.48
Structure of two unlinked Drosophila melanogaster glyceraldehyde-3-phosphate dehydrogenase genes. J Biol Chem (1985) 1.48
Control of glycolysis by phosphofructokinase in slices of rat liver, Novikoff hepatoma, and adenocarcinomas. Biochem Biophys Res Commun (1964) 1.47
Continuous multiplication of rabbit tracheal epithelial cells in a defined, hormone-supplemented medium. In Vitro (1982) 1.46
Induction of T-cell activation by oxidized low density lipoprotein. Arterioscler Thromb (1992) 1.46
Chemical synthesis of versatile adaptors for molecular cloning. Biochem Biophys Res Commun (1978) 1.45
Loss of FHIT expression in cervical carcinoma cell lines and primary tumors. Cancer Res (1997) 1.42
Transcription terminates at lambda tR1 in three clusters. Proc Natl Acad Sci U S A (1982) 1.42
A simple and rapid nucleotide sequencing strategy and its application in analyzing a rice histone 3 gene. Gene (1986) 1.40
Adaptors, linkers, and methylation. Methods Enzymol (1987) 1.39
BK virus DNA sequence: extent of homology with simian virus 40 DNA. Proc Natl Acad Sci U S A (1979) 1.39
Retracted Nucleotide sequences of mitochondrial ATPase subunit 9 genes from three lines of rice (Oryza sativa L.) Nucleic Acids Res (1990) 1.39
Recognition sequence of restriction endonuclease KpnI from Klebsiella pneumoniae. Nucleic Acids Res (1978) 1.38
Nucleotide sequence analysis of DNA. X. Complete nucleotide sequence of the cohesive ends of bacteriophage phi80 DNA. J Mol Biol (1973) 1.38
TP53 mutations are frequent in malignant NF1 tumors. Genes Chromosomes Cancer (1994) 1.37
Light-regulated and cell-specific expression of tomato rbcS-gusA and rice rbcS-gusA fusion genes in transgenic rice. Plant Physiol (1993) 1.37
The role of replication proteins in the regulation of bacteriophage T4 transcription. II. Gene 45 and late transcription uncoupled from replication. J Mol Biol (1975) 1.35
Identification and molecular cloning of a human selenocysteine insertion sequence-binding protein. A bifunctional role for DNA-binding protein B. J Biol Chem (1998) 1.33