Published in Biochemistry on October 26, 1982
Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction. FEBS J (2013) 1.68
Phosphotyrosyl protein phosphatases. Biochem J (1989) 1.49
The receptor-like protein tyrosine phosphatase HPTP alpha has two active catalytic domains with distinct substrate specificities. EMBO J (1991) 1.24
Membrane protein phosphotyrosine phosphatase in rabbit kidney. Proteolysis activates the enzyme and generates soluble catalytic fragments. Biochem J (1987) 1.10
Protein phosphotyrosine phosphatase purified from the particulate fraction of human placenta dephosphorylates insulin and growth-factor receptors. Biochem J (1988) 1.06
Raf-1 activates MAP kinase-kinase. Nature (1992) 7.05
Structurally distinct collagen types. Annu Rev Biochem (1980) 6.43
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. Cell (1990) 6.12
Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem Biophys Res Commun (1989) 4.63
The elastic fiber. I. The separation and partial characterization of its macromolecular components. J Cell Biol (1969) 4.51
The nature of the intramolecular cross-links in collagen. The separation and characterization of peptides from the cross-link region of rat skin collagen. Biochemistry (1966) 4.04
Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation. Science (1992) 3.64
Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis. J Cell Biol (1998) 3.27
Evidence for procollagen, a biosynthetic precursors of collagen. Proc Natl Acad Sci U S A (1971) 2.96
Mitochondrial cytochrome c: preparation and activity of native and chemically modified cytochromes c. Methods Enzymol (1978) 2.87
Correlation of procollagen mRNA levels in normal and transformed chick embryo fibroblasts with different rates of procollagen synthesis. Biochemistry (1978) 2.85
Cleavage at Asn-Gly bonds with hydroxylamine. Methods Enzymol (1977) 2.80
Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc Natl Acad Sci U S A (1988) 2.73
The biosynthesis of collagen. Annu Rev Biochem (1974) 2.50
Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin. J Biol Chem (1991) 2.47
Thrombospondin: synthesis and secretion by cells in culture. J Cell Biol (1982) 2.33
B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A. Proc Natl Acad Sci U S A (1997) 2.30
Correlation of the kinetics of electron transfer activity of various eukaryotic cytochromes c with binding to mitochondrial cytochrome c oxidase. J Biol Chem (1976) 2.25
Isolation and characterization of a glycoprotein secreted by aortic endothelial cells in culture. Apparent identity with platelet thrombospondin. J Biol Chem (1981) 2.25
Light microscopic immunolocation of thrombospondin in human tissues. J Histochem Cytochem (1985) 2.20
Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2. J Biol Chem (2000) 2.18
Protein phosphatase type 1 in mammalian cell mitosis: chromosomal localization and involvement in mitotic exit. J Cell Biol (1992) 2.16
Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin. Proc Natl Acad Sci U S A (1986) 2.10
Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission. Dev Dyn (1997) 2.05
Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells. J Cell Biol (1985) 2.05
Severe recurrent bacterial infections associated with defective adherence and chemotaxis in two patients with neutrophils deficient in a cell-associated glycoprotein. J Pediatr (1982) 2.03
Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture. J Biol Chem (1984) 2.01
Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis. Proc Natl Acad Sci U S A (1999) 2.01
Agonists trigger G protein-mediated activation of the CPI-17 inhibitor phosphoprotein of myosin light chain phosphatase to enhance vascular smooth muscle contractility. J Biol Chem (2000) 2.00
Cell surface-associated structural proteins in connective tissue cells. Proc Natl Acad Sci U S A (1977) 1.99
Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J Physiol (2001) 1.96
Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn. J Biol Chem (1981) 1.95
Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proc Natl Acad Sci U S A (1991) 1.94
Effects of antimicrotubular agents on the secretion of collagen. A biochemical and morphological study. J Cell Biol (1974) 1.93
Differential expression of thrombospondin 1, 2, and 3 during murine development. Dev Dyn (1993) 1.92
Modulation of calcium-activated potassium channels from rat brain by protein kinase A and phosphatase 2A. J Neurosci (1991) 1.90
An avian oncovirus mutant deficient in genomic RNA: characterization of the packaged RNA as cellular messenger RNA. Virology (1979) 1.89
Matricellular proteins as modulators of cell-matrix interactions: adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2. Mol Biol Cell (2000) 1.85
Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen. J Cell Biol (1984) 1.85
Isolation of a collagen-binding fragment from fibronectin and cold-insoluble globulin. J Biol Chem (1979) 1.80
Inhibiting effect of procollagen peptides on collagen biosynthesis in fibroblast cultures. J Biol Chem (1979) 1.80
Definition of cytochrome c binding domains by chemical modification. III. Kinetics of reaction of carboxydinitrophenyl cytochromes c with cytochrome c oxidase. J Biol Chem (1978) 1.79
Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts. J Biol Chem (1994) 1.79
Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene. J Invest Dermatol (1999) 1.79
Characterization of the pro- 1 chain of procollagen. J Biol Chem (1972) 1.78
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms. J Biol Chem (2001) 1.77
Isolation and characterization of the cyanogen bromide peptides from the alpha-1 chain of rat skin collagen. Biochemistry (1967) 1.77
Structural studies on human type IV collagen. J Biol Chem (1979) 1.77
Regulation of collagen gene expression. Prog Nucleic Acid Res Mol Biol (1989) 1.75
The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism. J Biol Chem (2001) 1.72
p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1. J Biol Chem (1999) 1.72
Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen. J Biol Chem (1986) 1.71
Protein phosphatase type-1, not type-2A, modulates actin microfilament integrity and myosin light chain phosphorylation in living nonmuscle cells. J Cell Biol (1990) 1.68
Coordinate transcriptional regulation of type I procollagen genes by Rous sarcoma virus. J Biol Chem (1981) 1.68
Involvement of protein phosphatases 1 and 2A in the control of M phase-promoting factor activity in starfish. J Cell Biol (1989) 1.66
Definitaion of cytochrome c binding domains by chemical modification. Reaction of carboxydinitrophenyl- and trinitrophenyl-cytochromes c with baker's yeast cytochrome c peroxidase. J Biol Chem (1978) 1.64
X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity. N Engl J Med (1980) 1.62
The nature and location of intramolecular cross-links in collagen. Proc Natl Acad Sci U S A (1966) 1.60
Protein phosphatase types 1 and/or 2A regulate nucleocytoplasmic shuttling of glucocorticoid receptors. Mol Endocrinol (1991) 1.59
Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs. Mol Pharmacol (1986) 1.58
Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. J Histochem Cytochem (1993) 1.56
Sulfated proteoglycans synthesized by vascular endothelial cells in culture. J Biol Chem (1983) 1.55
Protein phosphatases modulate the apparent agonist affinity of the light-regulated ion channel in retinal rods. Neuron (1992) 1.54
The amino acid sequence of peptides from the cross-linking region of rat skin collagen. Biochemistry (1967) 1.54
Microtubules in transcellular movement of procollagen. Nat New Biol (1972) 1.53
Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism. EMBO J (2001) 1.51
Secretory phenotypes of endothelial cells in culture: comparison of aortic, venous, capillary, and corneal endothelium. Arteriosclerosis (1982) 1.49
Insulin activates the kinase activity of the Raf-1 proto-oncogene by increasing its serine phosphorylation. J Biol Chem (1990) 1.49
TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ (2006) 1.47
Altered secretion of type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts. Lab Invest (1981) 1.46
Comparative sequence studies of rat skin and tendon collagen. I. Evidence for incomplete hydroxylation of individual prolyl residues in the normal proteins. Biochemistry (1967) 1.46
Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice. Am J Pathol (2001) 1.45
Synthesis of types I and III procollagen and collagen by monkey aortic smooth muscle cells in vitro. Biochemistry (1977) 1.44
Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity. Proc Natl Acad Sci U S A (1999) 1.42
Biochemical and ultrastructural studies of proteoheparan sulfates synthesized by PYS-2, a basement membrane-producing cell line. J Cell Biol (1982) 1.41
Collagen synthesis by bovine aortic endothelial cells in culture. Biochemistry (1979) 1.40
Inhibition of procollagen cell-free synthesis by amino-terminal extension peptides. Biochemistry (1979) 1.40
Structure of alpha-1-CB8, a large cyanogen bromide produced fragment from the alpha-1 chain of rat collagen. The nature of a hydroxylamine-sensitive bond and composition of tryptic peptides. Biochemistry (1970) 1.39
Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes. Proc Natl Acad Sci U S A (1982) 1.39
Cytosolic protein phosphotyrosine phosphatases from rabbit kidney. Purification of two distinct enzymes that bind to Zn2+-iminodiacetate agarose. J Biol Chem (1984) 1.37
T-cell interleukin 1 receptor cDNA expressed in Chinese hamster ovary cells regulates functional responses to interleukin 1. Proc Natl Acad Sci U S A (1989) 1.37
Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes. Proc Natl Acad Sci U S A (1988) 1.37
An upstream regulatory region mediates high-level, tissue-specific expression of the human alpha 1(I) collagen gene in transgenic mice. Mol Cell Biol (1991) 1.36
Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2. Biochemistry (1999) 1.36
Cytoskeletal integrity in interphase cells requires protein phosphatase activity. Proc Natl Acad Sci U S A (1992) 1.36
A presumptive subunit of elastic fiber microfibrils secreted by arterial smooth-muscle cells in culture. Eur J Biochem (1976) 1.36
The distribution of antigenic determinants in rat skin collagen. J Exp Med (1971) 1.35
Increased marrow-derived osteoprogenitor cells and endosteal bone formation in mice lacking thrombospondin 2. J Bone Miner Res (2000) 1.35
Isolation and characterization of the cyanogen bromide peptides from the alpha 1 and alpha 2 chains of human skin collagen. Biochemistry (1970) 1.34
NH2-terminal sequence of the chick proalpha1(I) chain synthesized in the reticulocyte lysate system. Evidence for a transient hydrophobic leader sequence. J Biol Chem (1979) 1.34
Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A. Nature (1994) 1.34
Transforming growth factor and epidermal growth factor stimulate the phosphorylation of a synthetic, tyrosine-containing peptide in a similar manner. J Biol Chem (1982) 1.34
Biosynthetic and structural properties of endothelial cell type VIII collagen. J Biol Chem (1983) 1.34
Metaxin is a component of a preprotein import complex in the outer membrane of the mammalian mitochondrion. J Biol Chem (1997) 1.32
Changes in surface properties of normal and transformed cells caused by tunicamycin, an inhibitor of protein glycosylation. Proc Natl Acad Sci U S A (1977) 1.32