Published in Nucleic Acids Res on January 25, 1983
Kinetics of target site localization of a protein on DNA: a stochastic approach. Biophys J (2004) 1.47
Interaction of EcoRII restriction and modification enzymes with synthetic DNA fragments. VI. The binding and cleavage of substrates containing nucleotide analogs. Nucleic Acids Res (1985) 1.40
Site directed mutagenesis experiments suggest that Glu 111, Glu 144 and Arg 145 are essential for endonucleolytic activity of EcoRI. Nucleic Acids Res (1986) 1.10
Nuclear proteins: finding and binding target sites in chromatin. Chromosome Res (2011) 1.01
A real-time assay for monitoring nucleic acid cleavage by quadruplex formation. Nucleic Acids Res (2006) 0.81
Searching for electrical properties, phenomena and mechanisms in the construction and function of chromosomes. Comput Struct Biotechnol J (2013) 0.75
DNA target sequence identification mechanism for dimer-active protein complexes. Nucleic Acids Res (2012) 0.75
The lac repressor-operator interaction. 3. Kinetic studies. J Mol Biol (1970) 10.07
Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory. Biochemistry (1981) 9.05
Diffusion controlled reaction rates in spheroidal geometry. Application to repressor--operator association and membrane bound enzymes. Biophys Chem (1974) 6.68
Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor--operator interaction: kinetic measurements and conclusions. Biochemistry (1981) 5.28
Diffusion-driven mechanisms of protein translocation on nucleic acids. 2. The Escherichia coli repressor--operator interaction: equilibrium measurements. Biochemistry (1981) 2.98
Involvement of outside DNA sequences in the major kinetic path by which EcoRI endonuclease locates and leaves its recognition sequence. Proc Natl Acad Sci U S A (1982) 2.29
The interaction of the EcoRI restriction endonuclease with its substrate. A physico-chemical study employing natural and synthetic oligonucleotides and polynucleotides. Eur J Biochem (1980) 1.75
Preparation of milligram amounts of 21 deoxyribonucleic acid restriction fragments. Biochemistry (1981) 1.73
The EcoRI restriction endonuclease with bacteriophage lambda DNA. Kinetic studies. Biochem J (1980) 1.67
Rate enhancement by guided diffusion. Chain length dependence of repressor-operator association rates. Biophys Chem (1978) 1.29
Non-specific binding of restriction endonuclease EcoR1 to DNA. Nucleic Acids Res (1980) 1.28
Substrate dependence of the mechanism of EcoRI endonuclease. Nucleic Acids Res (1978) 1.28
Inhibition of Eco RI action by polynucleotides. A characterization of the non-specific binding of the enzyme to DNA. Nucleic Acids Res (1980) 1.25
Transient cleavage kinetics of the Eco RI restriction endonuclease measured in a pulsed quench-flow apparatus: enzyme concentration-dependent activity change. Nucleic Acids Res (1981) 1.09
Gradient thin-layer chromatography of oligonucleotides on DEAE-cellulose: an alternative to homochromatography. Anal Biochem (1979) 0.83
DNA flexibility studied by covalent closure of short fragments into circles. Proc Natl Acad Sci U S A (1981) 5.44
Anomalous diffusion of fluorescent probes inside living cell nuclei investigated by spatially-resolved fluorescence correlation spectroscopy. J Mol Biol (2000) 3.65
Synthesis and characterization of an octanucleotide containing the EcoRI recognition sequence with a phosphorothioate group at the cleavage site. Biochemistry (1984) 3.03
Action at a distance: DNA-looping and initiation of transcription. Trends Biochem Sci (1995) 2.64
The conformational transitions in yeast tRNAPhe as studied with tRNAPhe fragments. Eur J Biochem (1973) 2.26
Compartmentalization of interphase chromosomes observed in simulation and experiment. J Mol Biol (1999) 2.21
Preventing the spread of vancomycin-resistant enterococci in a long-term care facility. J Am Geriatr Soc (2000) 2.00
Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase alpha primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts. Antimicrob Agents Chemother (1986) 1.83
Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems. J Mol Evol (1996) 1.82
The interaction of the EcoRI restriction endonuclease with its substrate. A physico-chemical study employing natural and synthetic oligonucleotides and polynucleotides. Eur J Biochem (1980) 1.75
A Brownian dynamics program for the simulation of linear and circular DNA and other wormlike chain polyelectrolytes. Biophys J (1998) 1.68
Influence of DNA target melting behavior on real-time PCR quantification. Clin Chem (2000) 1.66
A site-directed mutagenesis study to identify amino acid residues involved in the catalytic function of the restriction endonuclease EcoRV. Biochemistry (1992) 1.62
Infectious foot-and-mouth disease virus derived from a cloned full-length cDNA. J Virol (1990) 1.54
Linear diffusion of restriction endonucleases on DNA. J Biol Chem (1985) 1.54
Ternary complex formation between elongation factor Tu, GTP and aminoacyl-tRNA: an equilibrium study. Eur J Biochem (1977) 1.50
Assessing the flexibility of intermediate filaments by atomic force microscopy. J Mol Biol (2004) 1.49
Modulation of intramolecular interactions in superhelical DNA by curved sequences: a Monte Carlo simulation study. Biophys J (1995) 1.47
Pausing of the restriction endonuclease EcoRI during linear diffusion on DNA. Biochemistry (1994) 1.46
Increased rate of lupus flare during pregnancy and the puerperium: a prospective study of 78 pregnancies. Br J Rheumatol (1996) 1.44
Sequence-dependent elastic properties of DNA. J Mol Biol (2000) 1.43
Brownian dynamics simulations of supercoiled DNA with bent sequences. Biophys J (1996) 1.42
[Usefulness of intracoronary therapy with progenitor cells in patients with dilated cardiomyopathy: Bridge or alternative to heart transplantation?]. An Pediatr (Barc) (2011) 1.40
[Perinatal psychohygienics -- importance and chance of a primary preventive medicine by the gynaecologist (author's transl)]. Z Geburtshilfe Perinatol (1975) 1.40
Kinetic characterization of linear diffusion of the restriction endonuclease EcoRV on DNA. Biochemistry (1998) 1.39
Neutron and light-scattering studies of DNA gyrase and its complex with DNA. J Mol Biol (1990) 1.35
Role of thymidine residues in DNA recognition by the EcoRI and EcoRV restriction endonucleases. Nucleic Acids Res (1986) 1.34
Linear diffusion of the restriction endonuclease EcoRV on DNA is essential for the in vivo function of the enzyme. EMBO J (1996) 1.34
The stereochemical course of the restriction endonuclease EcoRI-catalyzed reaction. J Biol Chem (1984) 1.33
Isolation and identification of enteric adenoviruses. J Med Virol (1983) 1.32
Site-directed mutagenesis studies with EcoRV restriction endonuclease to identify regions involved in recognition and catalysis. Biochemistry (1991) 1.32
Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes. Proc Natl Acad Sci U S A (1993) 1.31
Looping dynamics of linear DNA molecules and the effect of DNA curvature: a study by Brownian dynamics simulation. Biophys J (1998) 1.31
Accuracy of the EcoRI restriction endonuclease: binding and cleavage studies with oligodeoxynucleotide substrates containing degenerate recognition sequences. Biochemistry (1990) 1.31
The influence of sequences adjacent to the recognition site on the cleavage of oligodeoxynucleotides by the EcoRI endonuclease. Eur J Biochem (1984) 1.30
Equivalent and non-equivalent binding sites for tRNA on aminoacyl-tRNA synthetases. Eur J Biochem (1975) 1.29
Mg2+ confers DNA binding specificity to the EcoRV restriction endonuclease. Biochemistry (1992) 1.27
Inhibition of Eco RI action by polynucleotides. A characterization of the non-specific binding of the enzyme to DNA. Nucleic Acids Res (1980) 1.25
Common structural features of different viroids: serial arrangement of double helical sections and internal loops. Nucleic Acids Res (1978) 1.22
Direct analysis of polymerase chain reaction products using enzyme-linked immunosorbent assay techniques. Anal Biochem (1991) 1.20
A mechanistic view of mitochondrial death decision pores. Braz J Med Biol Res (2007) 1.19
Evidence for an evolutionary relationship among type-II restriction endonucleases. Gene (1995) 1.19
Sau3AI, a monomeric type II restriction endonuclease that dimerizes on the DNA and thereby induces DNA loops. J Biol Chem (2001) 1.18
Computation of writhe in modeling of supercoiled DNA. Biopolymers (2000) 1.17
Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid. Virology (1994) 1.16
A fast and accurate enzyme-linked immunosorbent assay for the determination of the DNA cleavage activity of restriction endonucleases. Anal Biochem (1993) 1.16
Kinetics of conformational changes in tRNA Phe (yeast) as studied by the fluorescence of the Y-base and of formycin substituted for the 3'-terminal adenine. Biophys Chem (1975) 1.16
Cross-linking of bromodeoxyuridine-substituted oligonucleotides to the EcoRI and EcoRV restriction endonucleases. Eur J Biochem (1986) 1.16
The monomeric homing endonuclease PI-SceI has two catalytic centres for cleavage of the two strands of its DNA substrate. EMBO J (1999) 1.15
A similar active site for non-specific and specific endonucleases. Nat Struct Biol (1999) 1.15
Differential expression of NF-kappaB pathway genes among peripheral T-cell lymphomas. Leukemia (2005) 1.14
A comparison of the structural requirements for DNA cleavage by the isoschizomers HaeIII, BspRI and BsuRI. Eur J Biochem (1985) 1.14
[Experimental infection of cercopithecus aethiops with the agent of the Frankfut-Marburg syndrome (FMS)]. Z Med Mikrobiol Immunol (1968) 1.14
On the catalytic mechanism of EcoRI and EcoRV. A detailed proposal based on biochemical results, structural data and molecular modelling. FEBS Lett (1992) 1.14
Salt-dependent DNA superhelix diameter studied by small angle neutron scattering measurements and Monte Carlo simulations. Biophys J (1998) 1.13
Analysis of the mechanism of the Serratia nuclease using site-directed mutagenesis. Nucleic Acids Res (1996) 1.13
Distinct steps in the specific binding of tRNA to aminoacyl-tRNA synthetase. Temperature-jump studies on the serine-specific system from yeast and the tyrosine-specific system from Escherichia coli. Eur J Biochem (1976) 1.11
Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein. Proc Natl Acad Sci U S A (1996) 1.10
Site directed mutagenesis experiments suggest that Glu 111, Glu 144 and Arg 145 are essential for endonucleolytic activity of EcoRI. Nucleic Acids Res (1986) 1.10
Salt effects on the structure and internal dynamics of superhelical DNAs studied by light scattering and Brownian dynamics. Biophys J (1997) 1.09
Transient cleavage kinetics of the Eco RI restriction endonuclease measured in a pulsed quench-flow apparatus: enzyme concentration-dependent activity change. Nucleic Acids Res (1981) 1.09
The elongation factor Tu binds aminoacyl-tRNA in the presence of GDP. J Biol Chem (1982) 1.09
Analysis of the recognition mechanism involved in the EcoRV catalyzed cleavage of DNA using modified oligodeoxynucleotides. Nucleic Acids Res (1988) 1.08
DNA curvature influences the internal motions of supercoiled DNA. EMBO J (1993) 1.08
The coagulation/fibrinolysis balance in systemic sclerosis: evidence for a haematological stress syndrome. Br J Rheumatol (1997) 1.07
On the possibilities and limitations of rational protein design to expand the specificity of restriction enzymes: a case study employing EcoRV as the target. Protein Eng (2000) 1.06
Mechanism of discrimination between cognate and non-cognate tRNAs by phenylalanyl-tRNA synthetase from yeast. Eur J Biochem (1976) 1.06
The effect of several nucleic acid binding drugs on the cleavage of d(GGAATTCC) and pBR 322 by the Eco RI restriction endonuclease. Nucleic Acids Res (1981) 1.05
Noncyclic crown-type polyethers, pyridinophane cryptands, and their alkali metal ion complexes: synthesis, complex stability, and kinetics. J Am Chem Soc (1977) 1.04
Cystic fibrosis with three mutations in the cystic fibrosis transmembrane conductance regulator gene. Hum Genet (1991) 1.03
The binding of ethidium bromide to different conformations of tRNA. Unfolding of tertiary structure. Eur J Biochem (1973) 1.03
Binding, bending and cleavage of DNA substrates by the homing endonuclease Pl-SceI. Nucleic Acids Res (1996) 1.03
Tertiary structure of tRNAPhe (yeast): kinetics and electrostatic repulsion. Eur J Biochem (1975) 1.03
Probing the indirect readout of the restriction enzyme EcoRV. Mutational analysis of contacts to the DNA backbone. J Biol Chem (1996) 1.03
DNA binding specificity of the EcoRV restriction endonuclease is increased by Mg2+ binding to a metal ion binding site distinct from the catalytic center of the enzyme. Biochemistry (1995) 1.03