Published in Biochemistry on January 04, 1983
The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc Natl Acad Sci U S A (1990) 4.46
Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci U S A (1990) 2.68
Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes. Biochem J (1987) 2.54
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc Natl Acad Sci U S A (1987) 1.89
Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor. J Clin Invest (1985) 1.61
Activation of the endogenous metalloproteinase, gelatinase, by triggered human neutrophils. Proc Natl Acad Sci U S A (1986) 1.57
Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis. Proc Natl Acad Sci U S A (1986) 1.44
The precursor of a metalloendopeptidase from human rheumatoid synovial fibroblasts. Purification and mechanisms of activation by endopeptidases and 4-aminophenylmercuric acetate. Biochem J (1988) 1.30
Structure-function relationship of human neutrophil collagenase: identification of regions responsible for substrate specificity and general proteinase activity. Proc Natl Acad Sci U S A (1993) 1.14
Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo. EMBO J (1990) 1.13
Procollagenase activator produced by rabbit uterine cervical fibroblasts. Biochem J (1987) 1.03
CD43, the major sialoglycoprotein of human leukocytes, is proteolytically cleaved from the surface of stimulated lymphocytes and granulocytes. Proc Natl Acad Sci U S A (1993) 0.99
The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite. J Biol Chem (2011) 0.97
Neutrophil elastase cleaves VEGF to generate a VEGF fragment with altered activity. Am J Physiol Lung Cell Mol Physiol (2009) 0.92
Collagenases and the serine proteinases elastase and cathepsin G in steroid-induced Pneumocystis carinii pneumonia. J Clin Microbiol (1995) 0.89
Mouse matrix metalloprotease-1a (Mmp1a) gives new insight into MMP function. J Cell Physiol (2014) 0.83
Evidence for polymorphonuclear leukocyte collagenase and 92-kilodalton gelatinase in gingival crevicular fluid. Infect Immun (1991) 0.79
Purification and characterization of a connective-tissue-degrading metalloproteinase from the cytosol of metastatic melanoma cells. Biochem J (1987) 0.77
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J Biol Chem (1989) 5.64
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem (1988) 4.06
Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. J Biol Chem (1986) 3.67
Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J Clin Invest (1990) 2.56
Studies on collagenase from rheumatoid synovium in tissue culture. J Clin Invest (1968) 2.42
Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures. Biochemistry (1977) 2.39
The collagen substrate specificity of human skin fibroblast collagenase. J Biol Chem (1981) 2.26
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Human collagenase: identification and characterization of an enzyme from rheumatoid synovium in culture. Science (1967) 2.15
Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2. Proc Natl Acad Sci U S A (1989) 2.12
Collagenase production by human skin fibroblasts. Biochem Biophys Res Commun (1975) 2.12
Human skin collagenase. Isolation and mechanism of attack on the collagen molecule. Biochim Biophys Acta (1968) 2.05
Comparison of nerve cell and nerve cell plus Schwann cell cultures, with particular emphasis on basal lamina and collagen formation. J Cell Biol (1980) 1.96
Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid. J Biol Chem (1983) 1.89
Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc Natl Acad Sci U S A (1987) 1.89
The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products. J Biol Chem (1987) 1.78
Scleroderma: increased biosynthesis of triple-helical type I and type III procollagens associated with unaltered expression of collagenase by skin fibroblasts in culture. J Clin Invest (1979) 1.73
Connective tissue nevi of the skin. Clinical, genetic, and histopathologic classification of hamartomas of the collagen, elastin, and proteoglycan type. J Am Acad Dermatol (1980) 1.71
Stat1 depends on transcriptional synergy with Sp1. J Biol Chem (1995) 1.66
Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells. Cell (1991) 1.65
Primary structure and cDNA cloning of human fibroblast collagenase inhibitor. Proc Natl Acad Sci U S A (1986) 1.63
Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem (1990) 1.63
Direct suppression of Stat1 function during adenoviral infection. Immunity (1998) 1.62
Cutaneous mycobacteriosis: analysis of 34 cases with a new classification of the disease. Medicine (Baltimore) (1981) 1.57
A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. J Clin Invest (1996) 1.57
Human skin collagenase: relationship to the pathogenesis of epidermolysis bullosa dystrophica. J Invest Dermatol (1969) 1.54
Inhibition of human skin collagenase by human serum. J Lab Clin Med (1970) 1.53
The collagen substrate specificity of human neutrophil collagenase. J Biol Chem (1987) 1.49
Human skin fibroblast collagenase inhibitor. Purification and biochemical characterization. J Biol Chem (1983) 1.49
Extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma. J Am Acad Dermatol (1992) 1.48
Isolated osteoclasts resorb the organic and inorganic components of bone. J Cell Biol (1986) 1.47
Human skin fibroblast collagenase: chemical properties of precursor and active forms. Biochemistry (1978) 1.47
Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis. Proc Natl Acad Sci U S A (1986) 1.44
The North American experience with photopheresis. Ther Apher (1999) 1.42
Enzyme-linked immunosorbent assay for human skin collagenase. Coll Relat Res (1983) 1.38
A specific inhibitor of vertebrate collagenase produced by human skin fibroblasts. J Biol Chem (1979) 1.37
Human skin fibroblast collagenase: interaction with substrate and inhibitor. Coll Relat Res (1985) 1.37
Collagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalization. J Biol Chem (1999) 1.36
Quantitation and immunocytochemical localization of human skin collagenase in basal cell carcinoma. J Invest Dermatol (1977) 1.33
Human skin collagenase. The role of serum alpha-globulins in the control of activity in vivo and in vitro. Proc Natl Acad Sci U S A (1971) 1.31
Collagenase from rat uterus. Isolation and partial characterization. Biochemistry (1970) 1.30
Human skin collagenase: localization and distribution in normal human skin. J Invest Dermatol (1969) 1.28
Differential susceptibility of type X collagen to cleavage by two mammalian interstitial collagenases and 72-kDa type IV collagenase. J Biol Chem (1990) 1.28
Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity. J Clin Invest (1991) 1.25
Different collagenase gene products have different roles in degradation of type I collagen. J Biol Chem (1996) 1.23
Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. J Biol Chem (2001) 1.23
EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. Int J Dev Biol (1991) 1.22
Type X collagen contains two cleavage sites for a vertebrate collagenase. J Biol Chem (1986) 1.22
Initiation of osteoclast bone resorption by interstitial collagenase. J Biol Chem (1997) 1.21
Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. J Invest Dermatol (1991) 1.21
The collagen substrate specificity of rat uterus collagenase. J Biol Chem (1983) 1.20
Targeted inhibition of interferon-gamma-dependent intercellular adhesion molecule-1 (ICAM-1) expression using dominant-negative Stat1. J Biol Chem (1997) 1.19
Human skin fibroblast collagenase. Assessment of activation energy and deuterium isotope effect with collagenous substrates. J Biol Chem (1981) 1.17
Platelet-derived collagenase inhibitor: characterization and subcellular localization. Proc Natl Acad Sci U S A (1985) 1.15
Purification and properties of a gelatin-specific neutral protease from human skin. J Biol Chem (1981) 1.15
Purification and properties of rat uterine procollagenase. Arch Biochem Biophys (1983) 1.15
The gelatinolytic activity of rat uterus collagenase. J Biol Chem (1985) 1.13
The function of Ca+ in the action of mammalian collagenases. Arch Biochem Biophys (1976) 1.13
Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury. Am J Pathol (1996) 1.13
Animal and human collagenases. J Invest Dermatol (1970) 1.12
The gelatinolytic activity of human skin fibroblast collagenase. J Biol Chem (1982) 1.12
Studies on purified rheumatoid synovial collagenase in vitro and in vivo. J Clin Invest (1971) 1.12
The role of epithelium and mesenchyme in the production of a collagenolytic enzyme and a hyaluronidase in the anuran tadpole. Dev Biol (1965) 1.12
Cleavage of type VII collagen by interstitial collagenase and type IV collagenase (gelatinase) derived from human skin. J Biol Chem (1989) 1.11
Post-transcriptional inhibition of collagen and fibronectin synthesis by a synthetic homolog of a portion of the carboxyl-terminal propeptide of human type I collagen. J Biol Chem (1986) 1.10
Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase. J Invest Dermatol (1995) 1.10
Collagenase in human cornea: immunologic localization. Arch Ophthalmol (1980) 1.09
Cleavage specificity of human skin type IV collagenase (gelatinase). Identification of cleavage sites in type I gelatin, with confirmation using synthetic peptides. J Biol Chem (1990) 1.07
Regulation of human skin collagenase activity by hydrocortisone and dexamethasone in organ culture. Biochem Biophys Res Commun (1974) 1.07
Expression of 92-kDa type IV collagenase mRNA by eosinophils associated with basal cell carcinoma. J Invest Dermatol (1992) 1.07
Morphea and lichen sclerosus et atrophicus. Clinical and histopathologic studies in patients with combined features. J Am Acad Dermatol (1980) 1.06
A sensitive microassay for prolyl hydroxylase: activity in normal and psoriatic skin. J Invest Dermatol (1973) 1.06
The role of ascorbic acid in the biosynthesis of collagen. I. Ascorbic acid requirement by embryonic chick tibia in tissue culture. Biochim Biophys Acta (1966) 1.06