Published in J Neurophysiol on March 01, 1983
The nature of feelings: evolutionary and neurobiological origins. Nat Rev Neurosci (2013) 1.76
Sex differences in the anatomical and functional organization of the periaqueductal gray-rostral ventromedial medullary pathway in the rat: a potential circuit mediating the sexually dimorphic actions of morphine. J Comp Neurol (2006) 1.23
Defining the neurocircuitry of exercise hyperpnoea. J Physiol (2013) 1.18
Temporal filtering of nociceptive information by dynamic activation of endogenous pain modulatory systems. J Neurosci (2009) 1.17
Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions. Expert Rev Neurother (2012) 1.05
Neural circuits controlling diaphragm function in the cat revealed by transneuronal tracing. J Appl Physiol (1985) (2008) 0.98
The role of the periaqueductal gray in the modulation of pain in males and females: are the anatomy and physiology really that different? Neural Plast (2009) 0.93
Effect of direct eye contact in PTSD related to interpersonal trauma: an fMRI study of activation of an innate alarm system. Soc Cogn Affect Neurosci (2012) 0.89
Defense-like behaviors evoked by pharmacological disinhibition of the superior colliculus in the primate. J Neurosci (2013) 0.89
Neural substrates underlying fear-evoked freezing: the periaqueductal grey-cerebellar link. J Physiol (2014) 0.86
Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology. Brain Pathol (2015) 0.86
Mindfulness meditation-based pain relief: a mechanistic account. Ann N Y Acad Sci (2016) 0.80
Amygdala lesions in rhesus macaques decrease attention to threat. Nat Commun (2015) 0.80
Mindfulness-Meditation-Based Pain Relief Is Not Mediated by Endogenous Opioids. J Neurosci (2016) 0.80
The efference cascade, consciousness, and its self: naturalizing the first person pivot of action control. Front Psychol (2013) 0.80
GABAA receptor signaling in caudal periaqueductal gray regulates maternal aggression and maternal care in mice. Behav Brain Res (2010) 0.79
The degree of acute descending control of spinal nociception in an area of primary hyperalgesia is dependent on the peripheral domain of afferent input. J Physiol (2014) 0.79
Neuronal relationships between the dorsal periaqueductal nucleus and the inferior colliculus (nucleus commissuralis) in the cat. A Golgi study. J Anat (1988) 0.76
Cat's medullary reticulospinal and subnucleus reticularis dorsalis noxious neurons form a coupled neural circuit through collaterals of descending axons. J Neurophysiol (2015) 0.75
Primary afferent tachykinins are required to experience moderate to intense pain. Nature (1998) 2.97
Origins of skeletal pain: sensory and sympathetic innervation of the mouse femur. Neuroscience (2002) 2.57
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cord. Nat Med (2000) 2.54
Transmission of chronic nociception by spinal neurons expressing the substance P receptor. Science (1999) 2.43
Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism. Biochemistry (2000) 2.37
Murine models of inflammatory, neuropathic and cancer pain each generates a unique set of neurochemical changes in the spinal cord and sensory neurons. Neuroscience (2000) 2.28
The molecular dynamics of pain control. Nat Rev Neurosci (2001) 2.21
Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. J Neurosci (1999) 2.19
Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proc Natl Acad Sci U S A (1988) 1.87
Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo. J Neurosci (1998) 1.68
NMDA-receptor regulation of substance P release from primary afferent nociceptors. Nature (1997) 1.65
Point substitution in the central hydrophobic cluster of a human beta-amyloid congener disrupts peptide folding and abolishes plaque competence. Biochemistry (1996) 1.58
Diversity in mammalian tachykinin peptidergic neurons: multiple peptides, receptors, and regulatory mechanisms. FASEB J (1990) 1.51
1H NMR of A beta amyloid peptide congeners in water solution. Conformational changes correlate with plaque competence. Biochemistry (1995) 1.48
Reversible in vitro growth of Alzheimer disease beta-amyloid plaques by deposition of labeled amyloid peptide. Proc Natl Acad Sci U S A (1992) 1.41
A beta deposition inhibitor screen using synthetic amyloid. Nat Biotechnol (1997) 1.37
Inflammation increases the distribution of dorsal horn neurons that internalize the neurokinin-1 receptor in response to noxious and non-noxious stimulation. J Neurosci (1997) 1.33
Spinal substance P receptor expression and internalization in acute, short-term, and long-term inflammatory pain states. J Neurosci (1999) 1.32
Substance P activation of enteric neurons in response to intraluminal Clostridium difficile toxin A in the rat ileum. Gastroenterology (1996) 1.32
Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain. Neuroscience (2010) 1.31
Expression and localization of endothelin receptors: implications for the involvement of peripheral glia in nociception. J Neurosci (2001) 1.28
Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations. Biochemistry (1999) 1.27
Brain amyloid--a physicochemical perspective. Brain Pathol (1996) 1.27
Spinal cord substance P receptor immunoreactivity increases in both inflammatory and nerve injury models of persistent pain. Neuroscience (1996) 1.22
Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid. J Struct Biol (2000) 1.20
In vitro growth of Alzheimer's disease beta-amyloid plaques displays first-order kinetics. Biochemistry (1996) 1.19
Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis. J Comp Neurol (1995) 1.19
Synaptic relationship between substance P and the substance P receptor: light and electron microscopic characterization of the mismatch between neuropeptides and their receptors. Proc Natl Acad Sci U S A (1994) 1.19
Osteoprotegerin diminishes advanced bone cancer pain. Cancer Res (2001) 1.19
Noxious cutaneous thermal stimuli induce a graded release of endogenous substance P in the spinal cord: imaging peptide action in vivo. J Neurosci (1997) 1.18
The majority of myelinated and unmyelinated sensory nerve fibers that innervate bone express the tropomyosin receptor kinase A. Neuroscience (2011) 1.16
Endothelin and the tumorigenic component of bone cancer pain. Neuroscience (2004) 1.14
Spinal opioid analgesia: how critical is the regulation of substance P signaling? J Neurosci (1999) 1.10
Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. Nature (1984) 1.09
Differential expression of substance P receptors in patients with Crohn's disease and ulcerative colitis. Gastroenterology (1995) 1.06
Peripheral patterns of calcitonin-gene-related peptide general somatic sensory innervation: cutaneous and deep terminations. J Comp Neurol (1989) 1.06
Bone cancer pain: from mechanism to model to therapy. Pain Med (2000) 1.05
Forebrain projections to the periaqueductal gray in the monkey, with observations in the cat and rat. J Comp Neurol (1982) 1.04
Intra-arterial infusion of [125I]A beta 1-40 labels amyloid deposits in the aged primate brain in vivo. Neuroreport (1996) 1.01
Capsaicin-sensitive sensory nerve fibers contribute to the generation and maintenance of skeletal fracture pain. Neuroscience (2009) 1.00
Delayed behavioral effects following intrahippocampal injection of aggregated A beta (1-42). Brain Res (1999) 0.98
Localization of specific binding sites for atrial natriuretic factor in peripheral tissues of the guinea pig, rat, and human. Hypertension (1986) 0.97
Connections of midbrain periaqueductal gray in the monkey. I. Ascending efferent projections. J Neurophysiol (1983) 0.96
Primary afferent fibers that contribute to increased substance P receptor internalization in the spinal cord after injury. J Neurophysiol (1999) 0.94
Neuropeptides are present in projection neurones at all levels in visceral and taste pathways: from periphery to sensory cortex. Brain Res (1984) 0.94
Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices. Brain Res (1984) 0.93
Substance P receptors: localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand. Brain Res (1984) 0.92
Trigeminal and dorsal root ganglion neurons express CCK receptor binding sites in the rat, rabbit, and monkey: possible site of opiate-CCK analgesic interactions. J Neurosci (1992) 0.91
Increased substance P receptor expression by blood vessels and lymphoid aggregates in Clostridium difficile-induced pseudomembranous colitis. Dig Dis Sci (1996) 0.91
The autoradiographic distribution of kassinin and substance K binding sites is different from the distribution of substance P binding sites in rat brain. Eur J Pharmacol (1984) 0.90
Beta-adrenergic receptors regulate astrogliosis and cell proliferation in the central nervous system in vivo. Glia (1996) 0.90
Distribution of calcitonin gene-related peptide immunoreactivity in relation to the rat central somatosensory projection. J Comp Neurol (1988) 0.89
A quantitative analysis of the sensory and sympathetic innervation of the mouse pancreas. Neuroscience (2006) 0.88
Calcitonin gene-related peptide (CGRP) in the rat central nervous system: patterns of immunoreactivity and receptor binding sites. Brain Res (1988) 0.87
Substance P and substance K receptor binding sites in the human gastrointestinal tract: localization by autoradiography. Peptides (1989) 0.87
The localization of sensory nerve fibers and receptor binding sites for sensory neuropeptides in canine mesenteric lymph nodes. Peptides (1988) 0.87
Stereochemical specificity of Alzheimer's disease beta-peptide assembly. Biopolymers (1999) 0.86
The midbrain periaqueductal gray in the rat, cat, and monkey: a Nissl, Weil, and Golgi analysis. J Comp Neurol (1982) 0.86
Zinc-induced aggregation of human and rat beta-amyloid peptides in vitro. J Neurochem (1996) 0.86
Spinal projections from the periaqueductal grey and dorsal raphe in the rat, cat and monkey. Neuroscience (1982) 0.85
Cellular and neurochemical remodeling of the spinal cord in bone cancer pain. Prog Brain Res (2000) 0.85
The involvement of prostaglandins in tumorigenesis, tumor-induced osteolysis and bone cancer pain. J Musculoskelet Neuronal Interact (2002) 0.85
Thyrotropin-releasing hormone (TRH) receptors. Localization by light microscopic autoradiography in rat brain using [3H][3-Me-His2]TRH as the radioligand. J Neurosci (1985) 0.84
Localization of specific binding sites for atrial natriuretic factor in the central nervous system of rat, guinea pig, cat and human. Brain Res (1987) 0.83
Calcitonin gene-related peptide-alpha receptor binding sites in the gastrointestinal tract. Neuroscience (1989) 0.83
Enhanced responses of spinal dorsal horn neurons to heat and cold stimuli following mild freeze injury to the skin. J Neurophysiol (2001) 0.83
The autoradiographic localization of substance P receptors in the rat and bovine spinal cord and the rat and cat spinal trigeminal nucleus pars caudalis and the effects of neonatal capsaicin. Brain Res (1985) 0.83
Localization of specific binding sites for bombesin in the canine gastrointestinal tract. Gastroenterology (1987) 0.83
Evidence for vasoactive intestinal polypeptide as a neurotransmitter in smooth muscle of the urogenital tract. Brain Res (1984) 0.82
Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors. Neurosci Lett (1994) 0.82
Efferent connections of the subfascicular area of the mesodiencephalic junction and its possible involvement in stimulation-produced analgesia. Brain Res (1983) 0.82
The ascending input to the midbrain periaqueductal gray of the primate. J Comp Neurol (1982) 0.82
Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum. Nature (1984) 0.81
Neuropeptide Y/peptide YY receptor binding sites in the heart: localization and pharmacological characterization. Neuroscience (1993) 0.81
Expression of endothelin-B receptors by glia in vivo is increased after CNS injury in rats, rabbits, and humans. Exp Neurol (1997) 0.81
Cholecystokinin and neuropeptide Y receptors on single rabbit vagal afferent ganglion neurons: site of prejunctional modulation of visceral sensory neurons. Brain Res (1994) 0.81
Characterization of bombesin receptors on canine antral gastrin cells. Peptides (1990) 0.81
Bone cancer pain and the role of RANKL/OPG. J Musculoskelet Neuronal Interact (2004) 0.80
Epidermal growth factor receptors in the canine antrum. Peptides (1989) 0.80
Deposition of soluble amyloid-beta onto amyloid templates: with application for the identification of amyloid fibril extension inhibitors. Methods Enzymol (1999) 0.80
Spinal afferents to the ventrobasal thalamic complex in the rat: an anatomical study using wheat-germ agglutinin conjugated to horseradish peroxidase. Brain Res (1983) 0.80
Substance K and substance P in the ventral tegmental area. Neurosci Lett (1985) 0.80
Postnatal development of NK1, NK2, and NK3 neurokinin receptors expression in the rat retina. Brain Res Dev Brain Res (1999) 0.80
Radiation treatment decreases bone cancer pain, osteolysis and tumor size. Radiat Res (2004) 0.80
Evidence for cholecystokinin-like immunoreactive neurons in the rat medulla oblongata which project to the spinal cord. Brain Res (1984) 0.80
Radioimmunocytochemistry with [3H]biotin. Brain Res (1984) 0.79
Epidermal growth factor receptors in the human colon. Eur J Pharmacol (1988) 0.79
Mosaic distribution of neurotensin-like immunoreactivity in the cat striatum. Brain Res (1983) 0.79
Changes in 3H-substance P receptor binding in the rat brain after kainic acid lesion of the corpus striatum. J Neurosci (1986) 0.79
Estrous cyclicity of 125I-cholecystokinin octapeptide binding in the ventromedial hypothalamic nucleus. Evidence for downmodulation by estrogen. Neuroendocrinology (1987) 0.79
Differential localization of cholecystokinin-8 binding sites in the rat vs. the guinea pig brain. Eur J Pharmacol (1985) 0.78
Vasoactive intestinal peptide (VIP) receptors in the canine gastrointestinal tract. Peptides (1989) 0.78
Neurochemical plasticity in persistent inflammatory pain. Prog Brain Res (2000) 0.78
Vasoactive intestinal polypeptide receptor binding sites in the human gastrointestinal tract: localization by autoradiography. Neuroscience (1989) 0.78
Bombesin/GRP-preferring and neuromedin B-preferring receptors in the rat urogenital system. Neuropeptides (1993) 0.78
The terminations of the spinothalamic tract in the cat. Neurosci Lett (1983) 0.77
Substance P receptors on canine chief cells: localization, characterization, and function. J Neurosci (1989) 0.77
Bombesin receptors on gastrin cells. Ann N Y Acad Sci (1988) 0.77
A relationship between substance P receptor and retinal fibers in the rat suprachiasmatic nucleus. Brain Res (1995) 0.77
New insights into the neuropathology and cell biology of Alzheimer's disease. Geriatrics (1997) 0.77