PubRank

T Atkinson

Author PubWeight™ 122.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Characterization of a short, cis-acting DNA sequence which conveys cell cycle stage-dependent transcription in Saccharomyces cerevisiae. Mol Cell Biol 1991 2.91
2 A specific, highly active malate dehydrogenase by redesign of a lactate dehydrogenase framework. Science 1988 2.63
3 A specific endonuclease from Bacillus caldolyticus. Nucleic Acids Res 1978 2.18
4 Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesis. Cell 1984 2.12
5 Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos Trans R Soc Lond B Biol Sci 1991 2.02
6 Resisting and promoting new technologies in clinical practice: the case of telepsychiatry. Soc Sci Med 2001 1.84
7 Binding and hydrolysis of nucleotides in the chaperonin catalytic cycle: implications for the mechanism of assisted protein folding. Biochemistry 1993 1.78
8 The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene. Eur J Biochem 1990 1.78
9 Cloning, expression and complete nucleotide sequence of the Bacillus stearothermophilus L-lactate dehydrogenase gene. Gene 1986 1.76
10 Molecular evolution of bacterial cell-surface proteins. Trends Biochem Sci 1993 1.72
11 The complete nucleotide sequence of the Pseudomonas gene coding for carboxypeptidase G2. Gene 1984 1.57
12 Molecular cloning of the Pseudomonas carboxypeptidase G2 gene and its expression in Escherichia coli and Pseudomonas putida. J Bacteriol 1983 1.54
13 Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence. Appl Environ Microbiol 1992 1.47
14 Site-directed mutagenesis reveals role of mobile arginine residue in lactate dehydrogenase catalysis. Nature 1987 1.43
15 The purification of restriction endonuclease EcoRI by precipitation involving polyethyleneimine. FEBS Lett 1977 1.42
16 Metabolic engineering of Geobacillus thermoglucosidasius for high yield ethanol production. Metab Eng 2009 1.41
17 Nucleotide sequence of the Erwinia chrysanthemi NCPPB 1066 L-asparaginase gene. Gene 1986 1.31
18 The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene. Eur J Biochem 1992 1.30
19 An investigation of the contribution made by the carboxylate group of an active site histidine-aspartate couple to binding and catalysis in lactate dehydrogenase. Biochemistry 1988 1.25
20 Triazine-dye affinity; chromatography. Biochem Soc Trans 1981 1.24
21 The use of genetically engineered tryptophan to identify the movement of a domain of B. stearothermophilus lactate dehydrogenase with the process which limits the steady-state turnover of the enzyme. Biochem Biophys Res Commun 1988 1.18
22 A new rapid procedure for the preparation of plasmid DNA. Anal Biochem 1986 1.17
23 Isolation and partial characterization of four plasmids from antibiotic-resistant thermophilic bacilli. J Gen Microbiol 1979 1.11
24 The energetics and cooperativity of protein folding: a simple experimental analysis based upon the solvation of internal residues. Biochemistry 1993 1.08
25 From analysis to synthesis: new ligand binding sites on the lactate dehydrogenase framework. Part II. Trends Biochem Sci 1989 1.06
26 The replication proteins of plasmids pE194 and pLS1 have N-terminal homology. Nucleic Acids Res 1988 1.05
27 A strong carboxylate-arginine interaction is important in substrate orientation and recognition in lactate dehydrogenase. Biochim Biophys Acta 1987 1.05
28 Affinity of chaperonin-60 for a protein substrate and its modulation by nucleotides and chaperonin-10. Biochem J 1994 1.05
29 Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals. J Neurosci 2000 1.04
30 Cloning and complete nucleotide sequence of the Bacillus stearothermophilus tryptophanyl tRNA synthetase gene. Gene 1986 1.04
31 Sequential 1H NMR assignments and secondary structure of an IgG-binding domain from protein G. Biochemistry 1991 1.03
32 The influence of changes in tension on protein synthesis and prostaglandin release in isolated rabbit muscles. Biochem J 1983 1.03
33 From analysis to synthesis: new ligand binding sites on the lactate dehydrogenase framework. Part I. Trends Biochem Sci 1989 1.03
34 Nucleotide sequence analysis of the gene for protein A from Staphylococcus aureus Cowan 1 (NCTC8530) and its enhanced expression in Escherichia coli. Gene 1987 1.03
35 The stability and hydrophobicity of cytosolic and mitochondrial malate dehydrogenases and their relation to chaperonin-assisted folding. FEBS Lett 1994 1.01
36 Affinity labelling of enzymes with triazine dyes. Isolation of a peptide in the catalytic domain of horse-liver alcohol dehydrogenase using Procion blue MX-R as a structural probe. Eur J Biochem 1982 1.01
37 The social costs of unemployment: implications for social support. J Health Soc Behav 1986 1.00
38 Designs for a broad substrate specificity keto acid dehydrogenase. Biochemistry 1990 1.00
39 Characterization of Bacillus stearothermophilus plasmid pab124 and construction of deletion variants. J Gen Microbiol 1980 1.00
40 Nucleotide sequence of the thymidylate synthetase gene (thyP3) from the Bacillus subtilis phage phi 3T. Gene 1985 1.00
41 The importance of arginine 102 for the substrate specificity of Escherichia coli malate dehydrogenase. Biochem Biophys Res Commun 1992 0.98
42 Detection and characterization of intermediates in the folding of large proteins by the use of genetically inserted tryptophan probes. Biochemistry 1991 0.97
43 Cloning and overexpression of Lactobacillus helveticus D-lactate dehydrogenase gene in Escherichia coli. Eur J Biochem 1992 0.97
44 Expression in Escherichia coli of a synthetic gene coding for horse heart myoglobin. Protein Eng 1991 0.96
45 The effect of lactation length on the circulating concentrations of progesterone and oestradiol in the early weaned sow. Theriogenology 1981 0.95
46 Isolation and characterisation of the glycerol dehydrogenase from Bacillus stearothermophilus. Biochim Biophys Acta 1989 0.94
47 Enhanced plasma persistence of therapeutic enzymes by coupling to soluble dextran. Biochem J 1977 0.93
48 Cloning and nucleotide sequences of the mdh and sucD genes from Thermus aquaticus B. FEMS Microbiol Lett 1990 0.92
49 The purification and characterization of glucokinase from the thermophile Bacillus stearothermophilus. Biochem J 1986 0.90
50 A single amino acid substitution deregulates a bacterial lactate dehydrogenase and stabilizes its tetrameric structure. Biochim Biophys Acta 1987 0.90
51 Erwinia chrysanthemi L-asparaginase: epitope mapping and production of antigenically modified enzymes. Biochem J 1994 0.90
52 An outbreak of avian malaria in captive yellowheads/mohua (Mohoua ochrocephala). N Z Vet J 2008 0.89
53 The application of triazine dye affinity chromatography to the large-scale purification of glycerokinase from Bacillus stearothermophilus. Anal Biochem 1983 0.88
54 Hypothalamic NPY and prepro-NPY mRNA in Djungarian hamsters: effects of food deprivation and photoperiod. Am J Physiol 1995 0.88
55 The binding of aminoacyl-tRNA synthetases to triazine dye conjugates. Nucleic Acids Res 1979 0.87
56 The rapid purification of 3-hydroxybutyrate dehydrogenase and malate dehydrogenase on triazine dye affinity matrices. Biochem J 1982 0.87
57 Cloning, expression and purification of Ppl-1, a kappa-chain binding protein, based upon protein L from Peptostreptococcus magnus. Bioseparation 1995 0.87
58 Expression and purification of a truncated recombinant streptococcal protein G. Biochem J 1990 0.86
59 The importance of arginine 171 in substrate binding by Bacillus stearothermophilus lactate dehydrogenase. Biochem Biophys Res Commun 1987 0.86
60 The functional units of a peptostreptococcal protein L. Mol Microbiol 1994 0.86
61 Isolation of thrombin inhibitor from the leech Hirudinaria manillensis. Blood Coagul Fibrinolysis 1991 0.86
62 Dopamine-beta-hydroxylase deficiency in humans. Neurology 1990 0.85
63 Amino acid sequence of the L-lactate dehydrogenase of Bacillus caldotenax deduced from the nucleotide sequence of the cloned gene. Eur J Biochem 1987 0.85
64 The isolation and characterization of bacteriophages infecting obligately thermophilic strains of Bacillus. J Gen Microbiol 1986 0.85
65 Molecular cloning and nucleotide sequence determination of the Bacillus stearothermophilus NCA 1503 superoxide dismutase gene and its overexpression in Escherichia coli. Appl Microbiol Biotechnol 1991 0.85
66 Restriction endonucleases and modification methylases in bacteria. Biochem Soc Trans 1978 0.84
67 The interaction of tryptophanyl-tRNA synthetase with the triazine dye Brown MX-5BR. Eur J Biochem 1982 0.84
68 The engineering of a more thermally stable lactate dehydrogenase by reduction of the area of a water-accessible hydrophobic surface. Biochim Biophys Acta 1987 0.84
69 Gene K of bacteriophage phi X174 codes for a protein which affects the burst size of phage production. J Virol 1985 0.83
70 Rational construction of a 2-hydroxyacid dehydrogenase with new substrate specificity. Biochem Biophys Res Commun 1987 0.83
71 Gram-scale purification of methionyl-tRNA and tyrosyl-tRNA synthetases from Escherichia coli. Eur J Biochem 1975 0.83
72 Persistence of virulent Semliki Forest virus in mouse brain following co-inoculation with defective interfering particles. J Gen Virol 1986 0.82
73 Toxicity of paraquat to microorganisms. Appl Environ Microbiol 1986 0.82
74 Phase I/II dose finding study of combination cisplatin and gemcitabine in patients with recurrent cervix cancer. Gynecol Oncol 2006 0.82
75 Protein kinase activities in cell-free extracts of Streptomyces coelicolor A3(2). Biochimie 1990 0.82
76 Overexpression of the Thermus aquaticus B malate dehydrogenase-encoding gene in Escherichia coli. Gene 1992 0.81
77 Contribution of a buried aspartate residue towards the catalytic efficiency and structural stability of Bacillus stearothermophilus lactate dehydrogenase. Biochem J 1994 0.81
78 Influence of protein nutrition on the response of growing lambs to exogenous bovine growth hormone. J Endocrinol 1991 0.81
79 The isolation of a peptide from the catalytic domain of Bacillus stearothermophilus tryptophyl-tRNA synthetase. The interaction of Brown MX-5BR with tyrosyl-tRNA synthetase. Biochem J 1987 0.80
80 Dissecting the contributions of a specific side-chain interaction to folding and catalysis of Bacillus stearothermophilus lactate dehydrogenase. Eur J Biochem 1993 0.80
81 Recognition of pertussis toxin by antibodies to synthetic peptides. Mol Immunol 1990 0.80
82 Effect of bile salts and of fusidic acid on HIV-1 infection of cultured cells. Lancet 1988 0.80
83 Nucleotide sequence of an Erwinia chrysanthemi gene encoding shikimate kinase. Nucleic Acids Res 1989 0.80
84 Sequence of the Bacillus caldotenax and Bacillus stearothermophilus lctB genes. Nucleic Acids Res 1987 0.80
85 Regulation of galanin gene expression in the hypothalamic paraventricular nucleus of the obese Zucker rat by manipulation of dietary macronutrients. Brain Res Mol Brain Res 1996 0.80
86 Probing the substrate-binding sites of aminoacyl-tRNA synthetases with the procion dye green HE-4BD. Biochem J 1989 0.79
87 Cloning enzyme genes for overproduction. Biochem Soc Trans 1984 0.79
88 The potential of microbial enzymes as diagnostic reagents. Philos Trans R Soc Lond B Biol Sci 1983 0.79
89 The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus. Biochim Biophys Acta 1991 0.79
90 Short-day weight loss and effect of food deprivation on hypothalamic NPY and CRF mRNA in Djungarian hamsters. Am J Physiol 1997 0.79
91 Nucleotide sequence of the succinyl-CoA synthetase alpha-subunit from Thermus aquaticus B. Nucleic Acids Res 1988 0.79
92 An investigation of the thermal stabilities of two malate dehydrogenases by comparison of their three-dimensional structures. J Mol Graph 1994 0.79
93 Determination of protein size in chromatography column eluants by on-line photon correlation spectroscopy. Anal Biochem 1988 0.78
94 Rational design and PCR-based synthesis of an artificial Schizophyllum commune xylanase gene. Nucleic Acids Res 1993 0.78
95 Catalytic-rate improvement of a thermostable malate dehydrogenase by a subtle alteration in cofactor binding. Biochem J 1995 0.78
96 The secondary structure of protein G', a robust molecule. Biochem J 1991 0.78
97 Leptin (ob) mRNA and hypothalamic NPY in food-deprived/refed Syrian hamsters. Physiol Behav 1998 0.78
98 Effect of feeding melatonin to red deer (Cervus elaphus) on the onset of the breeding season. J Reprod Fertil 1984 0.78
99 Rapid large-scale preparation of recombinant Erwinia chrysanthemi L-asparaginase. Bioseparation 1992 0.78
100 pH-sensitive interactions between IgG and a mutated IgG-binding protein based upon two B domains of protein A from Staphylococcus aureus. Protein Eng 1992 0.78
101 Physical characterisation and over-expression of the Bacillus caldotenax superoxide dismutase gene. FEMS Microbiol Lett 1992 0.78
102 Mechanism of biodegradation of paraquat by Lipomyces starkeyi. Appl Environ Microbiol 1985 0.78
103 A rapid method for the accurate determination of lipid in animal tissues. Analyst 1972 0.78
104 Hypothalamic NPY and CRF gene expression in the food-deprived Syrian hamster. Physiol Behav 1996 0.78
105 Purification and properties of plasminogen activators from epithelial cells. Eur J Biochem 1985 0.77
106 Localisation of a receptor-recognition domain on the S3 subunit of pertussis toxin by peptide mapping. Eur J Biochem 1993 0.77
107 Colorimetric glucose assay using thermostable glucokinase. Ann Clin Biochem 1990 0.77
108 The use of site-directed mutagenesis and time-resolved fluorescence spectroscopy to assign the fluorescence contributions of individual tryptophan residues in Bacillus stearothermophilus lactate dehydrogenase. Biochim Biophys Acta 1987 0.77
109 Amplified expression and large-scale purification of protein L'. Bioseparation 1996 0.77
110 Effect of continuous infusion of thyrotrophin-releasing hormone on plasma prolactin and on ovarian activity in melatonin-treated ewes. J Reprod Fertil 1996 0.77
111 Collaborative trial of an enzyme-based assay for the determination of paracetamol in plasma. Ann Clin Biochem 1983 0.77
112 Expression of the copy DNA for human A4 and B4 L-lactate dehydrogenases in Escherichia coli. Biochim Biophys Acta 1990 0.77
113 The complete amino acid sequence of a hirudin variant from the leech Hirudinaria manillensis. J Protein Chem 1993 0.77
114 Synthesis and mutagenesis of an IgG-binding protein based upon protein A of Staphylococcus aureus. Protein Eng 1991 0.77
115 The inhibition of glucokinase and glycerokinase from Bacillus stearothermophilus by the triazine dye Procion Blue MX-3G. Biochem J 1987 0.76
116 Studies on the interactions of glycerol dehydrogenase from Bacillus stearothermophilus with Zn2+ ions and NADH. Biochim Biophys Acta 1990 0.76
117 The measurement of insulin-like growth factor 1 in sheep plasma. J Endocrinol 1991 0.76
118 Hyperleptinaemia precedes hyperinsulinaemia in Zucker (fa/fa) rats. Biochem Soc Trans 1998 0.76
119 Telepsychiatry evaluation in the north-west of England: preliminary results of a qualitative study. J Telemed Telecare 2000 0.76
120 Cholic acid derivatives against HIV replication. J Acquir Immune Defic Syndr 1990 0.75
121 Identification of a reversible structural transition in the metal-depleted glycerol dehydrogenase from Bacillus stearothermophilus. FEBS Lett 1990 0.75
122 Construction and characterization of a chimeric plasmid in Bacillus subtilis. Plasmid 1982 0.75
123 Colorimetric determination of human albumin. J Clin Pathol 1990 0.75
124 Regulation of food intake during growth in the Zucker rat. Proc Nutr Soc 1975 0.75
125 The optimal amino acid supplementation of barley for the growing pig. 1. Response of nitrogen metabolism to progressive supplementation. Br J Nutr 1979 0.75
126 Development of an enzyme-based assay for acetaminophen. Anal Biochem 1984 0.75
127 Kinetic studies of plasminogen activation by epithelial tissue plasminogen activator. Blood Coagul Fibrinolysis 1991 0.75
128 Preparative high-performance liquid affinity chromatography. J Chromatogr 1983 0.75
129 The use of tryptophan fluorescence to determine the stability of IgG binding proteins based upon the B domain of protein A from Staphylococcus aureus. Biochem Soc Trans 1992 0.75
130 Crystallization and X-ray analysis of a single fab binding domain from protein L of Peptostreptococcus magnus. Proteins 1995 0.75
131 A spectroscopic and conformational study of pertussis toxin. Eur J Biochem 1991 0.75
132 Plasma concentrations of progesterone in female red deer (Cervus elaphus) during the breeding season, pregnancy and anoestrus. J Reprod Fertil 1985 0.75
133 Large-scale protein extraction and isolation. Biochem Soc Trans 1990 0.75
134 Crystallization of glycerol dehydrogenase from Bacillus stearothermophilus. Acta Crystallogr D Biol Crystallogr 1995 0.75
135 Production of a fibrinolytic enzyme from cultures of guinea pig keratocytes grown on microcarriers. Dev Biol Stand 1983 0.75
136 Evaluation of epithelial tissue plasminogen activator as a thrombolytic agent in a rabbit model of venous thrombosis. J Pharmacol Exp Ther 1986 0.75
137 The effect of processing potatoes on the apparent digestion by pigs of organic matter and nitrogen measured overall and at the terminal. Proc Nutr Soc 1977 0.75
138 Light-scattering studies of protein association. Biochem Soc Trans 1991 0.75
139 Separation and purification of oligonucleotides using a new bonded-phase packing material. J Chromatogr 1991 0.75
140 Induction of early breeding in red deer (Cervus elaphus) by melatonin. J Reprod Fertil 1986 0.75
141 Localization of antigenic domains on the major subunits of Bordetella pertussis serotype 2 and 3 fimbriae. Microbiology 1994 0.75
142 Purification of homo- and hetero-oligonucleotides using high-performance charge-transfer chromatography. J Chromatogr 1986 0.75
143 In vitro studies on the fibrinolytic, thrombolytic and fibrinogenolytic properties of a tissue plasminogen activator from guinea pig keratocytes. Thromb Haemost 1985 0.75
144 Mutagenesis of the glycerol dehydrogenase from Bacillus stearothermophilus. Biochem Soc Trans 1992 0.75
145 Enzyme-based salicylate estimation. Lancet 1985 0.75
146 Psychiatry by videophone: a trial service in north west England. Stud Health Technol Inform 1999 0.75
147 Melatonin lowers plasma prolactin levels in female red deer (Cervus elaphus). J Pineal Res 1987 0.75
148 Development and validation of an automated, enzyme-mediated colorimetric assay of salicylate in serum. Clin Chem 1990 0.75
149 Secretion of pancreatic digestive enzymes induced in rats by first-time oral exposure to kidney bean E2L2 lectin is mediated only in part by cholecystokinin (CCK). Pancreas 1999 0.75
150 Substitution of the amino acid at position 102 with polar and aromatic residues influences substrate specificity of lactate dehydrogenase. J Protein Chem 1994 0.75
151 Rapid purification of glucokinase and glycerokinase from Bacillus stearothermophilus by hydrophobic interaction chromatography. J Chromatogr 1986 0.75
152 Biochemical characterisation of a pancreatic elastase inhibitor from the leech Hirudinaria manillensis. J Enzyme Inhib 1992 0.75
153 Application of photon correlation spectroscopy as a technique for detecting culture contamination. Biotechnol Bioeng 1991 0.75
154 Effect of hirudin on tissue plasminogen activator induced clot lysis. Blood Coagul Fibrinolysis 1990 0.75
155 A new enzymatic method for the determination of 3-methoxy-4-hydroxymandelic acid. Ann N Y Acad Sci 1992 0.75
156 Novel immunoglobulin binding proteins. Biochem Soc Trans 1992 0.75
157 Physico-chemical properties of recombinant desulphatohirudin. Thromb Haemost 1990 0.75
158 Development and validation of an automated enzyme assay for paracetamol (acetaminophen). Clin Chim Acta 1990 0.75
159 Is there evidence for a common amino acid sequence in proteins with membrane attaching ability? J Theor Biol 1986 0.75
160 Amplified expression and large-scale purification of protein G'. Bioseparation 1992 0.75
161 A comparison of the effects of various stimulatory agents on t-PA secretion by normal and malignant cell lines. Cell Biochem Funct 1989 0.75
162 Puerperal psychosis - a personal experience. Part 1. Through a husband's eyes. Part 2. Through a patient's eyes. Health Visit 1983 0.75
163 The relationship between carcinogenic activities of polycyclic aromatic hydrocarbons and their singlet, triplet, and singlet-triplet splitting energies of phosphorescence lifetimes. Photochem Photobiol 1977 0.75
164 Specificity of enzymic paracetamol assay. Ann Clin Biochem 1986 0.75
165 The effect of either raw or boiled potato juice on the digestibility of a diet based on barley in pigs. Proc Nutr Soc 1979 0.75
166 Analysis of pH-induced population oscillations of Saccharomyces cerevisiae and Escherichia coli using photon correlation spectroscopy. Biochem Soc Trans 1991 0.75
167 An enzyme mediated, colorimetric method for the measurement of salicylate. Clin Chim Acta 1986 0.75
168 The identification of a lysine residue reactive to pyridoxal-5-phosphate in the glycerol dehydrogenase from the thermophile Bacillus stearothermophilus. Biochim Biophys Acta 1993 0.75
169 Effects of reducing the remating interval after parturition on the fertility and plasma concentrations of luteinizing hormone, prolactin, oestradiol-17 beta and progesterone in lactating domestic rabbits. J Reprod Fertil 1991 0.75
170 Transcription of the Bacillus subtilis bacteriophage phi 3T in vitro. J Gen Virol 1985 0.75
171 The R-factors of multiple antibiotic resistant faecal coliforms isolated from a domestic dog. J Appl Bacteriol 1983 0.75
172 New tissue sources and types of fibrinolytic enzymes. Lancet 1982 0.75
173 Nanotechnology in medicine and the biosciences. The UK National Symposium on Nanotechnology in Medicine and the Biosciences, London, UK, 16-18 March l994. Trends Biotechnol 1994 0.75
174 Recombinant methionyl bovine prolactin: loss of bioactivity after single amino acid deletions from putative helical regions. Mol Endocrinol 1990 0.75
175 Properties of thyP3-containing plasmids in Bacillus subtilis. Plasmid 1983 0.75