Published in Biochemistry on July 31, 1984
The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins. J Cell Biol (1987) 3.22
Glycosylation and secretion of human tissue plasminogen activator in recombinant baculovirus-infected insect cells. Mol Cell Biol (1989) 1.87
Reduction of endogenous GRP78 levels improves secretion of a heterologous protein in CHO cells. Mol Cell Biol (1988) 1.46
Regulation of N-linked core glycosylation: use of a site-directed mutagenesis approach to identify Asn-Xaa-Ser/Thr sequons that are poor oligosaccharide acceptors. Biochem J (1997) 1.36
Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases. Mol Cell Biol (1992) 1.09
Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain. EMBO J (1988) 1.08
Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation. Biochem J (1992) 0.98
Carbohydrate analysis throughout the development of a protein therapeutic. Glycoconj J (2009) 0.97
Tissue-type plasminogen activator as a therapeutic target in stroke. Expert Opin Ther Targets (2008) 0.95
Localization of the binding site of tissue-type plasminogen activator to fibrin. J Clin Invest (1986) 0.92
Involvement of finger domain and kringle 2 domain of tissue-type plasminogen activator in fibrin binding and stimulation of activity by fibrin. EMBO J (1986) 0.89
The mechanism of the reaction between human plasminogen-activator inhibitor 1 and tissue plasminogen activator. Biochem J (1990) 0.83
Impacts of tissue-type plasminogen activator (tPA) on neuronal survival. Front Cell Neurosci (2015) 0.80
N-glycoprotein macroheterogeneity: biological implications and proteomic characterization. Glycoconj J (2015) 0.77
The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans. Biochem J (1996) 0.75
Binding of tissue plasminogen activator to human aortic endothelial cells. Biochem J (1990) 0.75
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem (1989) 11.06
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A (1985) 6.20
Sequence determinants of cytosolic N-terminal protein processing. Eur J Biochem (1986) 5.59
Characteristics of short-chain alcohol dehydrogenases and related enzymes. Eur J Biochem (1991) 3.67
Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol (1999) 3.28
Galanin - a novel biologically active peptide from porcine intestine. FEBS Lett (1983) 3.12
The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations. Blood (2000) 3.09
Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes. Cell Mol Life Sci (2008) 3.07
Antibacterial peptides from pig intestine: isolation of a mammalian cecropin. Proc Natl Acad Sci U S A (1989) 2.59
Antibodies against a synthetic peptide identify the Epstein-Barr virus-determined nuclear antigen. Proc Natl Acad Sci U S A (1984) 2.40
Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme. Eur J Biochem (1984) 2.36
Intermediates in adenovirus assembly. J Virol (1976) 2.26
Structure of the IgG-binding regions of streptococcal protein G. EMBO J (1986) 2.20
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes Dev (2001) 2.17
Characteristics of alcohol/polyol dehydrogenases. The zinc-containing long-chain alcohol dehydrogenases. Eur J Biochem (1987) 2.17
Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue. Biochem Biophys Res Commun (1979) 2.16
Plasminogen, absorbed by Escherichia coli expressing curli or by Salmonella enteritidis expressing thin aggregative fimbriae, can be activated by simultaneously captured tissue-type plasminogen activator (t-PA). Mol Microbiol (1994) 2.09
Regression of colonic low grade B cell lymphoma of the mucosa associated lymphoid tissue type after eradication of Helicobacter pylori. Gut (2000) 2.08
Purification and biochemical characterization of the Epstein-Barr virus-determined nuclear antigen and an associated protein with a 53,000-dalton subunit. J Virol (1980) 2.07
N-terminally extended somatostatin: the primary structure of somatostatin-28. FEBS Lett (1980) 2.04
Structural analyses of mutant and wild-type alcohol dehydrogenases from drosophila melanogaster. Eur J Biochem (1976) 2.00
Amino acid sequence of PR-39. Isolation from pig intestine of a new member of the family of proline-arginine-rich antibacterial peptides. Eur J Biochem (1991) 1.95
Acetylation of Protein N-terminal amino groups structural observations on alpha-amino acetylated proteins. J Theor Biol (1975) 1.93
Central pattern generators for locomotion, with special reference to vertebrates. Annu Rev Neurosci (1985) 1.93
Structures of N-terminally acetylated proteins. Eur J Biochem (1985) 1.92
Specific binding of proinsulin C-peptide to human cell membranes. Proc Natl Acad Sci U S A (1999) 1.91
Alcohol and polyol dehydrogenases are both divided into two protein types, and structural properties cross-relate the different enzyme activities within each type. Proc Natl Acad Sci U S A (1981) 1.74
Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol (1995) 1.73
The primary structure of alcohol dehydrogenase from Drosophila lebanonensis. Extensive variation within insect 'short-chain' alcohol dehydrogenase lacking zinc. Eur J Biochem (1989) 1.70
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem (1984) 1.70
Structural homologies between prealbumin, gastrointestinal prohormones and other proteins. Nature (1981) 1.69
Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas. FEBS Lett (1999) 1.68
Two hydrophobic low-molecular-mass protein fractions of pulmonary surfactant. Characterization and biophysical activity. Eur J Biochem (1987) 1.67
Purification of Epstein-Barr virus DNA polymerase from P3HR-1 cells. J Virol (1985) 1.66
Gene expression of rat and human microsomal glutathione S-transferases. J Biol Chem (1988) 1.66
Multiple mRNA species for the precursor to an adenovirus-encoded glycoprotein: identification and structure of the signal sequence. Proc Natl Acad Sci U S A (1980) 1.66
Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations. Eur J Biochem (1985) 1.65
The two major isozymes of yeast alcohol dehydrogenase. Eur J Biochem (1979) 1.57
A super-family of medium-chain dehydrogenases/reductases (MDR). Sub-lines including zeta-crystallin, alcohol and polyol dehydrogenases, quinone oxidoreductase enoyl reductases, VAT-1 and other proteins. Eur J Biochem (1994) 1.56
Subunit conformation of yeast alcohol dehydrogenase. J Biol Chem (1978) 1.54
Medium- and short-chain dehydrogenase/reductase gene and protein families : the MDR superfamily. Cell Mol Life Sci (2008) 1.52
Escherichia coli ferredoxin NADP+ reductase: activation of E. coli anaerobic ribonucleotide reduction, cloning of the gene (fpr), and overexpression of the protein. J Bacteriol (1993) 1.49
Antibodies against synthetic peptides react with the second Epstein-Barr virus-associated nuclear antigen. EMBO J (1985) 1.48
Extended superfamily of short alcohol-polyol-sugar dehydrogenases: structural similarities between glucose and ribitol dehydrogenases. FEBS Lett (1984) 1.47
Horse liver alcohol dehydrogenase. The primary structure of the protein chain of the ethanol-active isoenzyme. Eur J Biochem (1970) 1.46
Hydrophobic surfactant-associated polypeptides: SP-C is a lipopeptide with two palmitoylated cysteine residues, whereas SP-B lacks covalently linked fatty acyl groups. Proc Natl Acad Sci U S A (1990) 1.45
Molecular cloning and amino acid sequence of human 5-lipoxygenase. Proc Natl Acad Sci U S A (1988) 1.45
Conformational and functional similarities between glutaredoxin and thioredoxins. EMBO J (1984) 1.44
Role of C-peptide in human physiology. Am J Physiol Endocrinol Metab (2000) 1.44
On the primary structure of human fibrinogen. Isolation and characterization of N-terminal fragments from plasmic digests. Eur J Biochem (1969) 1.42
Genetic polymorphism of alcohol dehydrogenase in europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology (2000) 1.41
Neural networks that co-ordinate locomotion and body orientation in lamprey. Trends Neurosci (1995) 1.41
Differences between alcohol dehydrogenases. Structural properties and evolutionary aspects. Eur J Biochem (1977) 1.40
Recommended nomenclature for the vertebrate alcohol dehydrogenase gene family. Biochem Pharmacol (1999) 1.39
Purification and characterization of the phosphorylated DNA-binding protein from adenovirus-type-2-infected cells. Eur J Biochem (1977) 1.39
Activation of NMDA-receptors elicits "fictive locomotion" in lamprey spinal cord in vitro. Acta Physiol Scand (1981) 1.39
Proinsulin C-peptide--a consensus statement. Int J Exp Diabetes Res (2001) 1.38
Intrinsic function of a neuronal network - a vertebrate central pattern generator. Brain Res Brain Res Rev (1998) 1.38
Antibacterial components in bronchoalveolar lavage fluid from healthy individuals and sarcoidosis patients. Am J Respir Crit Care Med (1999) 1.37
Three-dimensional imaging of neurons by confocal fluorescence microscopy. J Microsc (1989) 1.36
Structure of betaine aldehyde dehydrogenase at 2.1 A resolution. Protein Sci (1998) 1.36
Molecular cloning and amino acid sequence of leukotriene A4 hydrolase. Proc Natl Acad Sci U S A (1987) 1.34
Isolation and characterization of porcine diazepam-binding inhibitor, a polypeptide not only of cerebral occurrence but also common in intestinal tissues and with effects on regulation of insulin release. Eur J Biochem (1988) 1.34
Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates. FEBS Lett (1999) 1.34
C-peptide is a bioactive peptide. Diabetologia (2007) 1.34
Fictive locomotion in the lamprey spinal cord in vitro compared with swimming in the intact and spinal animal. J Physiol (1984) 1.33
Purification and structural characterization of placental NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family. Biochemistry (1990) 1.33
The cytoplasmic isoenzyme of horse liver aldehyde dehydrogenase. Relationship to the corresponding human isoenzyme. Eur J Biochem (1984) 1.32
Class III human liver alcohol dehydrogenase: a novel structural type equidistantly related to the class I and class II enzymes. Biochemistry (1988) 1.32
Biochemical and antibacterial analysis of human wound and blister fluid. Eur J Biochem (1996) 1.32
Characterization of human plasminogen. II. Separation and partial characterization of different molecular forms of human plasminogen. Biochim Biophys Acta (1972) 1.31
Effect of ipratropium bromide treatment on oxygen saturation and sleep quality in COPD. Chest (1999) 1.31
Microsomal glutathione transferase. Primary structure. J Biol Chem (1985) 1.31
The neuronal correlate of locomotion in fish. "Fictive swimming" induced in an in vitro preparation of the lamprey spinal cord. Exp Brain Res (1980) 1.29
Enzyme relationships in a sorbitol pathway that bypasses glycolysis and pentose phosphates in glucose metabolism. Proc Natl Acad Sci U S A (1983) 1.29
Secondary structure and orientation of the surfactant protein SP-B in a lipid environment. A Fourier transform infrared spectroscopy study. Biochemistry (1992) 1.28
Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial. JAMA (1999) 1.28
cDNA sequence of human class III alcohol dehydrogenase. Biochem Biophys Res Commun (1989) 1.28
Structural features of lipoprotein lipase. Lipase family relationships, binding interactions, non-equivalence of lipase cofactors, vitellogenin similarities and functional subdivision of lipoprotein lipase. Eur J Biochem (1989) 1.26
Structural comparisons of mammalian, yeast and bacillar alcohol dehydrogenases. J Mol Biol (1976) 1.26
95- and 25-kDa fragments of the human immunodeficiency virus envelope glycoprotein gp120 bind to the CD4 receptor. Proc Natl Acad Sci U S A (1988) 1.26
A possible glycine radical in anaerobic ribonucleotide reductase from Escherichia coli: nucleotide sequence of the cloned nrdD gene. Proc Natl Acad Sci U S A (1993) 1.25
Structural evidence for three different types of glutathione transferase in human tissues. FEBS Lett (1985) 1.25
Structure and orientation of the surfactant-associated protein C in a lipid bilayer. Eur J Biochem (1992) 1.24
An amphipathic helical motif common to tumourolytic polypeptide NK-lysin and pulmonary surfactant polypeptide SP-B. FEBS Lett (1995) 1.24
The primary structure of Escherichia coli glutaredoxin. Distant homology with thioredoxins in a superfamily of small proteins with a redox-active cystine disulfide/cysteine dithiol. Eur J Biochem (1983) 1.23
Structure of a heat-stable enterotoxin produced by a human strain of Escherichia coli. Differences from the toxin of another human strain suggest the presence of compensated amino acid exchanges. FEBS Lett (1983) 1.23
Cytosolic rat liver glutathione transferase 4-4. Primary structure of the protein reveals extensive differences between homologous glutathione transferases of classes alpha and mu. Eur J Biochem (1986) 1.22
Activation of human plasminogen by an insoluble derivative of urokinase. Structural changes of plasminogen in the course of activation to plasmin and demonstration of a possible intermediate compound. Eur J Biochem (1973) 1.22
Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme. J Bacteriol (1991) 1.22
Neuronal network generating locomotor behavior in lamprey: circuitry, transmitters, membrane properties, and simulation. Annu Rev Neurosci (1991) 1.22
Partial similarities between yeast and liver alcohol dehydrogenases. Proc Natl Acad Sci U S A (1973) 1.22
Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis. J Biol Chem (1994) 1.21
Active site directed mutagenesis of 3 beta/17 beta-hydroxysteroid dehydrogenase establishes differential effects on short-chain dehydrogenase/reductase reactions. Biochemistry (1997) 1.20
Isolation and characterization of a somatomedin-binding protein from mid-term human amniotic fluid. Eur J Biochem (1984) 1.20
Horse liver alcohol dehydrogenase. The primary structure of an N-terminal part of the protein chain of the ethanol-active isoenzyme. Eur J Biochem (1970) 1.20
Forms and functions of human SDR enzymes. Chem Biol Interact (2001) 1.19
Comparison of three classes of human liver alcohol dehydrogenase. Emphasis on different substrate binding pockets. Eur J Biochem (1990) 1.19
Cytosolic glutathione transferases from rat liver. Primary structure of class alpha glutathione transferase 8-8 and characterization of low-abundance class Mu glutathione transferases. Biochem J (1989) 1.19