Published in J Cell Biol on October 01, 1983
Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. J Clin Invest (1985) 3.49
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Factor B, the complement alternative pathway serine proteinase, is a major constitutive protein synthesized and secreted by resident and elicited mouse macrophages. J Exp Med (1985) 0.89
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The presence of two Fc receptors on mouse macrophages: evidence from a variant cell line and differential trypsin sensitivity. J Exp Med (1977) 3.55
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Regulation of plasma cholesterol by lipoprotein receptors. Science (1981) 3.36
Increased production of superoxide anion by macrophages exposed in vitro to muramyl dipeptide or lipopolysaccharide. J Exp Med (1980) 3.13
Surface properties of bacillus Calmette-Guérin-activated mouse macrophages. Reduced expression of mannose-specific endocytosis, Fc receptors, and antigen F4/80 accompanies induction of Ia. J Exp Med (1981) 2.89
Fibronectin binding to Staphylococcus aureus. J Biol Chem (1982) 2.54
Fibronectin is produced by human macrophages. J Exp Med (1980) 2.44
Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E. Proc Natl Acad Sci U S A (1981) 2.30
Expression of the macrophage-specific antigen F4/80 during differentiation of mouse bone marrow cells in culture. J Exp Med (1981) 2.25
Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes. J Biol Chem (1982) 2.19
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Differentiation of macrophages from normal human bone marrow in liquid culture. Electron microscopy and cytochemistry. J Clin Invest (1978) 1.44
Independent pathways for secretion of cholesterol and apolipoprotein E by macrophages. Science (1983) 1.39
Sequential expression of functions during macrophage differentiation in murine bone marrow liquid cultures. Eur J Immunol (1980) 1.33
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Ultrastructure of mononuclear phagocytes developing in liquid bone marrow cultures. A study on peroxidatic activity. J Exp Med (1979) 1.17
Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages. J Exp Med (1983) 1.16
Apoprotein E suppresses phytohemagglutinin-activated phospholipid turnover in peripheral blood mononuclear cells. J Biol Chem (1982) 1.13
Human macrophages synthesize and secrete a major 95,000-dalton gelatin-binding protein distinct from fibronectin. J Biol Chem (1982) 1.05
Glucocorticoid receptors and glucocorticoid-sensitive secretion of neutral proteinases in a macrophage line. J Immunol (1978) 1.02
Proliferative capacity of mouse peritoneal macrophages in vitro. J Exp Med (1978) 0.95
Immunoregulatory plasma low density lipoprotein: the biologic activity and receptor-binding specificity is independent of neutral lipids. J Immunol (1981) 0.86
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VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med (1999) 9.18
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Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science (1995) 6.35
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev (1999) 6.10
The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. Cell (1999) 6.08
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Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest (2000) 4.79
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Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature (1995) 4.56
Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts. Proc Natl Acad Sci U S A (1982) 4.54
Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J Cell Biol (1997) 4.22
Endogenous activiation of latent collagenase by rheumatoid synovial cells. Evidence for a role of plasminogen activator. N Engl J Med (1977) 3.81
Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression. J Cell Biol (1994) 3.68
Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis Rheum (2009) 3.61
Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates. J Biol Chem (1985) 3.51
Novel method for studying mRNA phenotypes in single or small numbers of cells. J Cell Biochem (1989) 3.30
Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution. J Cell Biol (1992) 3.29
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Plasma membrane synthesis in the macrophage following phagocytosis of polystyrene latex particles. J Biol Chem (1972) 3.10
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The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development (2001) 3.04
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Signal transduction by integrin receptors for extracellular matrix: cooperative processing of extracellular information. Curr Opin Cell Biol (1992) 2.91
Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways. Development (1996) 2.88
Matrix metalloproteinase 9 and vascular endothelial growth factor are essential for osteoclast recruitment into developing long bones. J Cell Biol (2000) 2.87
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Matrix metalloproteinases and the development of cancer. Chem Biol (1996) 2.63
A specific collagenase from rabbit fibroblasts in monolayer culture. Biochem J (1974) 2.53
The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo. Cell (2000) 2.49
Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin. J Cell Biol (1995) 2.45
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Mouse macrophage elastase. Purification and characterization as a metalloproteinase. Biochem J (1981) 2.38
Stimulation by endocytosis of the secretion of collagenase and neutral proteinase from rabbit synovial fibroblasts. J Exp Med (1974) 2.36
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Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity. J Biol Chem (1986) 2.26
Initial events during phagocytosis by macrophages viewed from outside and inside the cell: membrane-particle interactions and clathrin. J Cell Biol (1982) 2.25
Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc Natl Acad Sci U S A (1996) 2.24
Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths. Development (1992) 2.19
Defective trophoblast function in mice with a targeted mutation of Ets2. Genes Dev (1998) 2.19
Biochemical actions of glucocorticoids on macrophages in culture. Specific inhibition of elastase, collagenase, and plasminogen activator secretion and effects on other metabolic functions. J Exp Med (1978) 2.18
Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties. J Biol Chem (1997) 2.15
The interaction of alpha2-macroglobulin with proteinases. Binding and inhibition of mammalian collagenases and other metal proteinases. Biochem J (1974) 2.11
Signaling through the stromal epidermal growth factor receptor is necessary for mammary ductal development. Development (1999) 2.04
Stromelysin-1 regulates adipogenesis during mammary gland involution. J Cell Biol (2001) 2.03
Degradation of connective tissue matrices by macrophages. I. Proteolysis of elastin, glycoproteins, and collagen by proteinases isolated from macrophages. J Exp Med (1980) 2.00
Gelatinase B-deficient mice are resistant to experimental bullous pemphigoid. J Exp Med (1998) 1.96
Cholesterol metabolism in the macrophage. 3. Ingestion and intracellular fate of cholesterol and cholesterol esters. J Exp Med (1972) 1.92
Compression-induced degeneration of the intervertebral disc: an in vivo mouse model and finite-element study. Spine (Phila Pa 1976) (1998) 1.90
Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase. J Biol Chem (1985) 1.86
Focalized proteolysis: spatial and temporal regulation of extracellular matrix degradation at the cell surface. Curr Opin Cell Biol (1996) 1.84
Hxt encodes a basic helix-loop-helix transcription factor that regulates trophoblast cell development. Development (1995) 1.82
Matrix metalloproteinase-9/gelatinase B is required for process outgrowth by oligodendrocytes. J Neurosci (1999) 1.81
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The fibroblastic coconspirator in cancer progression. Cold Spring Harb Symp Quant Biol (2005) 1.56
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Expression and function of FGF-4 in peri-implantation development in mouse embryos. Development (1994) 1.51
A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation. Nat Cell Biol (2001) 1.51
Isolation of a nonmitogenic angiogenesis factor from wound fluid. Proc Natl Acad Sci U S A (1982) 1.50
Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development. Genes Dev (2000) 1.48
Lactational competence and involution of the mouse mammary gland require plasminogen. Development (2000) 1.48
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Targeted mutagenesis of Timp-1 reveals that lung tumor invasion is influenced by Timp-1 genotype of the tumor but not by that of the host. Oncogene (1996) 1.46
Molecular genetics of implantation in the mouse. Dev Genet (1997) 1.46
Intervertebral disc cell death is dependent on the magnitude and duration of spinal loading. Spine (Phila Pa 1976) (2000) 1.45
Matrix metalloproteinase 9 protects mice from anti-glomerular basement membrane nephritis through its fibrinolytic activity. J Exp Med (2001) 1.43
Purification and characterization of an elastinolytic proteinase secreted by cercariae of Schistosoma mansoni. J Biol Chem (1985) 1.43
Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid. J Clin Invest (2001) 1.42
High-resolution three-dimensional views of membrane-associated clathrin and cytoskeleton in critical-point-dried macrophages. J Cell Biol (1983) 1.42
Proteinases and extracellular matrix remodeling. Curr Opin Cell Biol (1989) 1.41
Reprogramming the cell cycle for endoreduplication in rodent trophoblast cells. Mol Biol Cell (1998) 1.40
Cytochalasin B increases collagenase production by cells in vitro. Nature (1975) 1.40
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Limited proteolysis by macrophage elastase inactivates human alpha 1-proteinase inhibitor. J Exp Med (1980) 1.38
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