Published in Nature on January 27, 1984
Platelet-derived growth factor-induced alterations in vinculin and actin distribution in BALB/c-3T3 cells. J Cell Biol (1985) 2.26
Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells. J Cell Biol (1985) 2.05
Regulation of the transcript for a lysosomal protein: evidence for a gene program modified by platelet-derived growth factor. Mol Cell Biol (1985) 1.04
Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers. Proc Natl Acad Sci U S A (1991) 1.01
Platelet-derived growth factor modulates epidermal growth factor receptors by a mechanism distinct from that of phorbol esters. Proc Natl Acad Sci U S A (1986) 0.94
A basic cytoplasmic protein (p27) induced by serum in growth-arrested 3T3 cells but constitutively expressed in primary fibroblasts. EMBO J (1986) 0.77
Induction of DNA synthesis in BALB/c 3T3 cells by serum components: reevaluation of the commitment process. Proc Natl Acad Sci U S A (1977) 5.20
Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc Natl Acad Sci U S A (1979) 4.32
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A (2001) 3.29
Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells. Mol Cell Biol (1989) 2.78
An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis. Proc Natl Acad Sci U S A (1978) 2.71
Isoleucine and valine metabolism in Escherichia coli. XXII. A pleiotropic mutation affecting induction of isomeroreductase activity. J Bacteriol (1973) 2.31
Platelet-derived growth factor-induced alterations in vinculin and actin distribution in BALB/c-3T3 cells. J Cell Biol (1985) 2.26
Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells. Exp Cell Res (1982) 2.13
Isoleucine and valine metabolism in Escherichia coli. XX. Multiple forms of acetohydroxy acid synthetase. Biochem Biophys Res Commun (1972) 2.07
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene (2000) 2.06
Regulation of the cell cycle machinery by oncogenic ras. Oncogene (1996) 1.92
Platelet-derived growth factor-modulated proteins: constitutive synthesis by a transformed cell line. Proc Natl Acad Sci U S A (1981) 1.90
Transforming viruses directly reduce the cellular growth requirement for a platelet derived growth factor. J Cell Physiol (1978) 1.79
Isoleucine and valine metabolism in Escherichia coli. XXI. Mutations affecting derepression and valine resistance. J Bacteriol (1973) 1.75
Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR). Oncogene (2000) 1.75
Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells. Mol Cell Biol (1996) 1.66
Neurotrophic protein S100 beta stimulates glial cell proliferation. Proc Natl Acad Sci U S A (1991) 1.40
Epidermal growth factor (EGF) is required only during the traverse of early G1 in PDGF stimulated density-arrested BALB/c-3T3 cells. Exp Cell Res (1983) 1.36
Inhibition of the mitogenic effects of plasma by a monoclonal antibody to somatomedin C. Proc Natl Acad Sci U S A (1984) 1.30
Interferon inhibits the establishment of competence in Go/S-phase transition. Science (1986) 1.26
Control of the Balb/c-3T3 cell cycle by nutrients and serum factors: analysis using platelet-derived growth factor and platelet-poor plasma. J Cell Physiol (1979) 1.24
A model of cell cycle control: sequential events regulated by growth factors. Mol Cell Endocrinol (1983) 1.23
Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity. Oncogene (2000) 1.16
Modulation of the epidermal growth factor receptor by platelet-derived growth factor and choleragen: effects on mitogenesis. Proc Natl Acad Sci U S A (1982) 1.16
Mitogenic activity elaborated by macrophage-like cell lines acts as competence factor(s) for BALB/c 3T3 cells. J Cell Physiol (1982) 1.15
P27Kip1 and p21Cip1 are not required for the formation of active D cyclin-cdk4 complexes. Mol Cell Biol (2003) 1.14
Epidermal growth factor stimulates formation of inositol phosphates in BALB/c/3T3 cells pretreated with cholera toxin and isobutylmethylxanthine. J Biol Chem (1988) 1.10
Sequential addition of platelet factor and plasma to BALB/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle. Proc Natl Acad Sci U S A (1980) 1.10
Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms. Mol Biol Cell (1993) 1.09
Persistence of the mitogenic response to platelet-derived growth factor (competence) does not reflect a long-term interaction between the growth factor and the target cell. J Cell Biol (1983) 1.05
Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model. Oncogene (2000) 1.02
Identification of the cellular mechanisms responsible for platelet-derived growth factor induced alterations in cytoplasmic vinculin distribution. J Cell Physiol (1986) 1.02
Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes. J Biol Chem (2000) 1.02
Macrophage-derived growth factor for fibroblasts and Interleukin-1 are distinct entities. J Leukoc Biol (1984) 1.02
p27Kip1 regulates T cell proliferation. J Biol Chem (2001) 1.02
Thymidine triphosphate synthesis in senescent WI38 cells. Relationship to loss of replicative capacity. Exp Cell Res (1983) 1.02
Transforming growth factor beta 1 and cAMP inhibit transcription of epidermal growth factor- and oncogene-induced transin RNA. J Biol Chem (1988) 1.01
Cyclic adenosine 3':5'-monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes. J Biol Chem (1976) 0.99
Paradigms of growth control: relation to Cdk activation. Sci STKE (2002) 0.98
Regulation of the Balb/c-3T3 cell cycle-effects of growth factors. J Supramol Struct (1980) 0.98
Analysis of cyclin D3-cdk4 complexes in fibroblasts expressing and lacking p27(kip1) and p21(cip1). Mol Cell Biol (2000) 0.98
Activation of p38 mitogen-activated protein kinase is required for tumor necrosis factor-alpha -supported proliferation of leukemia and lymphoma cell lines. J Biol Chem (2000) 0.97
Differential modulation of G1 cyclins and the Cdk inhibitor p27kip1 by platelet-derived growth factor and plasma factors in density-arrested fibroblasts. J Biol Chem (1996) 0.96
PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition. Oncogene (2000) 0.95
Commitment to differentiation and expression of early differentiation markers in murine keratinocytes in vitro are regulated independently of extracellular calcium concentrations. J Cell Biol (1993) 0.94
Platelet-derived growth factor modulates epidermal growth factor receptors by a mechanism distinct from that of phorbol esters. Proc Natl Acad Sci U S A (1986) 0.94
The role of p27kip1 in the in vitro differentiation of murine keratinocytes. Cell Growth Differ (1997) 0.93
Expression and growth inhibitory effect of decapentaplegic Vg-related protein 6: evidence for a regulatory role in keratinocyte differentiation. Proc Natl Acad Sci U S A (1994) 0.92
The role of cyclin D3-dependent kinase in the phosphorylation of p130 in mouse BALB/c 3T3 fibroblasts. J Biol Chem (1998) 0.92
Cyclin D3-associated kinase activity is regulated by p27kip1 in BALB/c 3T3 cells. Mol Biol Cell (1998) 0.91
Accumulation of p53 and reductions in XIAP abundance promote the apoptosis of prostate cancer cells. Cancer Res (2005) 0.91
Cellular response to platelet-derived growth factor (PDGF)-AB after down-regulation of PDGF alpha-receptors. Evidence that functional binding does not require alpha-receptors. J Biol Chem (1991) 0.90
Differential sensitivity of fibroblasts to epidermal growth factor is related to cyclic AMP concentration. J Cell Physiol (1984) 0.88
Control of late G0/G1 progression and protein modification by SmC/IGF I. Am J Physiol (1987) 0.88
p107 and p130 associated cyclin A has altered substrate specificity. J Biol Chem (1997) 0.88
Serum modification of cyclic nucleotide phosphodiesterase forms independent of protein synthesis. Biochem Biophys Res Commun (1976) 0.88
Tumor necrosis factor-alpha-induced proliferation of human Mo7e leukemic cells occurs via activation of nuclear factor kappaB transcription factor. J Biol Chem (1999) 0.87
Density-dependent growth inhibition of fibroblasts ectopically expressing p27(kip1). Mol Biol Cell (2000) 0.87
Cellular mechanisms regulating proliferation. Adv Second Messenger Phosphoprotein Res (1988) 0.87
Induction of NF-kappa B-like activity by platelet-derived growth factor in mouse fibroblasts. Mol Biol Cell (1992) 0.87
Cell cycle control: a complex issue. Cell Cycle (2004) 0.87
Role of Gadd45alpha in the density-dependent G1 arrest induced by p27(Kip1). Oncogene (2003) 0.87
Increases in cyclic AMP potentiate competence formation in BALB/c-3T3 cells. J Cell Physiol (1982) 0.86
STAT3 activation accompanies keratinocyte differentiation. Cell Growth Differ (1998) 0.86
Regulation of cyclin E and p27kip during mitosis in BALB/c 3T3 cells. Cell Growth Differ (1995) 0.85
Cyclic AMP potentiates down regulation of epidermal growth factor receptors by platelet-derived growth factor. Biochem Biophys Res Commun (1982) 0.85
Activation of mammalian cyclic AMP phosphodiesterases by trypsin. Biochim Biophys Acta (1978) 0.84
PDGF stimulates transient phosphorylation of 180,000 dalton protein. J Cell Biochem (1985) 0.83
A p27Kip1 mutant that does not inhibit CDK activity promotes centrosome amplification and micronucleation. Oncogene (2011) 0.83
The regulation of cell proliferation by serum growth factors. Ann N Y Acad Sci (1982) 0.82
Inhibition of BALB/c-3T3 cells in late G1: commitment to DNA synthesis controlled by somatomedin C. J Cell Physiol (1981) 0.82
Induction of expression of c-fos and c-myc protooncogenes by basic calcium phosphate crystal: effect of beta-interferon. Cancer Res (1989) 0.82
Elevated intracellular concentrations of cyclic AMP inhibited serum-stimulated, density-arrested BALB/c-3T3 cells in mid G1. J Cell Biochem (1982) 0.82
Sonication as a tool for the study of adenylyl cyclase activity. J Cyclic Nucleotide Res (1977) 0.81
Cell cycle dependent growth factor regulation of gene expression. J Cell Physiol (1989) 0.81
Effects of growth conditions on cyclic nucleotide phosphodiesterases of cultured fibroblasts. J Cyclic Nucleotide Res (1975) 0.81
Cell cycle-dependent gene expression in V point-arrested BALB/c-3T3 cells. J Cell Physiol (1993) 0.81
Mitogenic response to epidermal growth factor (EGF) modulated by platelet-derived growth factor in cultured fibroblasts. Exp Cell Res (1983) 0.80
Primary keratinocytes have an adhesion dependent S phase checkpoint that is absent in immortalized cell lines. Oncogene (1998) 0.80
Molecular mechanism of basic calcium phosphate crystal-induced mitogenesis. Role of protein kinase C. J Biol Chem (1989) 0.80
Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH727965 and a heat shock protein 90 inhibitor. Cell Death Dis (2013) 0.80
Separation of multiple forms of cyclic nucleotide phosphodiesterases from rat brain by isoelectrofocusing. Biochim Biophys Acta (1974) 0.79
Characterization of growth factor-modulated events regulating cellular proliferation. Methods Enzymol (1987) 0.79
Rapid induction of competence formation is PDGF-isoform specific. J Cell Biochem (1992) 0.78
Biochemical and functional discrimination of platelet-derived growth factor alpha and beta receptors in BALB/c-3T3 cells. J Biol Chem (1991) 0.78
Detergent solubility defines an alternative itinerary for a subpopulation of PDGF beta receptors. J Cell Physiol (1996) 0.78
Effect of ouabain on growth regulation by serum components in Balb/c-3T3 cells: inhibition of entry into S phase by decreased protein synthesis. J Cell Physiol (1980) 0.78
Constitutive RelB activation in v-Src-transformed fibroblasts: requirement for IkappaB degradation. J Cell Biochem (1999) 0.77
Characterization of cyclic nucleotide phosphodiesterases with multiple separation techniques. Arch Biochem Biophys (1976) 0.77
Isolation of an activator of multiple forms of cyclic nucleotides phosphodiesterase of rat cerebrum by isoelectric focusing. Biochim Biophys Acta (1975) 0.77
Heterologous regulation of EGF receptors in fibroblastic cells. J Cell Biochem (1987) 0.77
Selective interferon-alpha/beta effects on platelet-derived growth factor-stimulated processes in quiescent BALB/c-3T3 fibroblasts. J Interferon Res (1994) 0.77
Modulation of the platelet-derived growth factor induced replicative response. J Cell Physiol (1985) 0.76