Published in Nucleic Acids Res on January 25, 1983
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Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis. Nucleic Acids Res (1984) 3.00
A new general approach for the simultaneous chemical synthesis of large numbers of oligonucleotides: segmental solid supports. Nucleic Acids Res (1983) 2.48
Analytical studies of 'mixed sequence' oligodeoxyribonucleotides synthesized by competitive coupling of either methyl- or beta-cyanoethyl-N,N-diisopropylamino phosphoramidite reagents, including 2'-deoxyinosine. Nucleic Acids Res (1985) 1.27
Site-specifically modified oligodeoxyribonucleotides as templates for Escherichia coli DNA polymerase I. Proc Natl Acad Sci U S A (1985) 0.83
The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit beta-globin DNA. Nucleic Acids Res (1981) 9.56
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Solid phase synthesis of polynucleotides. VI. Further studies on polystyrene copolymers for the solid support. Nucleic Acids Res (1982) 6.38
High-pressure liquid chromatography in polynucleotide synthesis. Biochemistry (1978) 5.98
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Synthesis of mixed oligodeoxyribonucleotides following the solid phase method. Nucleic Acids Res (1982) 2.27
Identification of an H-2Kb-related molecule by molecular cloning. Immunogenetics (1981) 1.41
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell (1997) 18.91
Hybridization of synthetic oligodeoxyribonucleotides to phi chi 174 DNA: the effect of single base pair mismatch. Nucleic Acids Res (1979) 14.12
The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit beta-globin DNA. Nucleic Acids Res (1981) 9.56
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. Science (1977) 9.28
High-copy-number and low-copy-number plasmid vectors for lacZ alpha-complementation and chloramphenicol- or kanamycin-resistance selection. Gene (1987) 9.16
Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides. Proc Natl Acad Sci U S A (1983) 7.52
Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin. Proc Natl Acad Sci U S A (1981) 7.24
Crystal structure analysis of a complete turn of B-DNA. Nature (1980) 7.18
A high-density rice genetic linkage map with 2275 markers using a single F2 population. Genetics (1998) 6.82
Directed deletion of a yeast transfer RNA intervening sequence. Science (1980) 6.67
Solid phase synthesis of polynucleotides. VI. Further studies on polystyrene copolymers for the solid support. Nucleic Acids Res (1982) 6.38
Structure of a B-DNA dodecamer: conformation and dynamics. Proc Natl Acad Sci U S A (1981) 6.38
Chemical synthesis of genes for human insulin. Proc Natl Acad Sci U S A (1978) 6.09
High-salt d(CpGpCpG), a left-handed Z' DNA double helix. Nature (1980) 5.46
Synthetic lac operator DNA is functional in vivo. Nature (1976) 5.36
Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA. Proc Natl Acad Sci U S A (1983) 5.27
A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322. Gene (1981) 5.06
Global warming in the twenty-first century: an alternative scenario. Proc Natl Acad Sci U S A (2000) 5.02
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Chemical synthesis of restriction enzyme recognition sites useful for cloning. Science (1977) 4.81
Expression in Escherichia coli of chemically synthesized genes for human insulin. Proc Natl Acad Sci U S A (1979) 4.72
Solid-phase synthesis of polynucleotides. III. Synthesis of polynucleotides with defined sequences by the block coupling phosphotriester method. Nucleic Acids Res (1980) 4.69
Simplications in the synthesis of short oligonucleotide blocks. Nucleic Acids Res (1980) 4.64
Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function. Proc Natl Acad Sci U S A (1982) 4.64
Synthesis and use of synthetic oligonucleotides. Annu Rev Biochem (1984) 4.53
alpha 1-antitrypsin deficiency detection by direct analysis of the mutation in the gene. Nature (1983) 4.38
Efficient correction of a mutation by use of chemically synthesized DNA. Proc Natl Acad Sci U S A (1978) 4.13
Improved triester approach for the synthesis of pentadecathymidylic acid. J Am Chem Soc (1975) 4.08
Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA. Nucleic Acids Res (1981) 3.87
Rescue of a foreign gene by Sendai virus. Proc Natl Acad Sci U S A (1991) 3.85
Hemolysin of Streptococcus faecalis subspecies zymogenes contributes to virulence in mice. Infect Immun (1984) 3.83
Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone. Nature (1979) 3.80
Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution. Biochemistry (1982) 3.76
Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen. J Bacteriol (1984) 3.69
Hepatic artery embolization in 120 patients with unresectable hepatoma. Radiology (1983) 3.67
Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. Oncogene (1990) 3.66
Solid-phase synthesis of polynucleotides. IV. Usage of polystyrene resins for the synthesis of polydeoxyribonucleotides by the phosphostriester method. Nucleic Acids Res (1980) 3.59
A transcriptional enhancer sequence of HTLV-I is responsible for trans-activation mediated by p40 chi HTLV-I. EMBO J (1986) 3.53
Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity. Cancer Res (2001) 3.51
Role of positive charge on the amino-terminal region of the signal peptide in protein secretion across the membrane. Proc Natl Acad Sci U S A (1982) 3.44
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Genetic linkage relationships of loci specifying differentiation alloantigens in the mouse. Transplantation (1972) 3.34
Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn (1999) 3.33
Premelting and melting transitions in the d(CGCGAATTCGCG) self-complementary duplex in solution. Biochemistry (1982) 3.30
Trends of measured climate forcing agents. Proc Natl Acad Sci U S A (2001) 3.30
Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineage. Proc Natl Acad Sci U S A (1994) 3.25
Sequence analysis of termini of conjugative transposon Tn916. J Bacteriol (1988) 3.22
Three-dimensional solution structure of the B domain of staphylococcal protein A: comparisons of the solution and crystal structures. Biochemistry (1992) 3.20
Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method. Nucleic Acids Res (1980) 3.20
The use of arylsulfonyltriazoles for the synthesis of oligonucleotides by the triester approach. J Am Chem Soc (1975) 3.16
Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs. Nucleic Acids Res (1987) 3.05
Extra adenosine stacks into the self-complementary d(CGCAGAATTCGCG) duplex in solution. Biochemistry (1982) 3.02
Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer. Oncogene (2008) 2.83
Chemical synthesis and sequence studies of deoxyribooligonucleotides which constitute the duplex sequence of the lactose operator of Escherichia coli. J Biol Chem (1975) 2.79
Cloning and expression of cDNA for salmon growth hormone in Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.70
Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations. Proc Natl Acad Sci U S A (1999) 2.70
Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains. Science (2000) 2.67
Effects of the complete removal of basic amino acid residues from the signal peptide on secretion of lipoprotein in Escherichia coli. J Biol Chem (1983) 2.66
Comparative study on the antibacterial activity of phytochemical flavanones against methicillin-resistant Staphylococcus aureus. J Ethnopharmacol (1996) 2.57
PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet (1997) 2.44
Deoxyguanosine-deoxyadenosine pairing in the d(C-G-A-G-A-A-T-T-C-G-C-G) duplex: conformation and dynamics at and adjacent to the dG X dA mismatch site. Biochemistry (1984) 2.44
High incidence of hemolysin production by Enterococcus (Streptococcus) faecalis strains associated with human parenteral infections. J Clin Microbiol (1987) 2.42
Isolation and characterization of fra-2, an additional member of the fos gene family. Proc Natl Acad Sci U S A (1990) 2.40
Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma. Cancer (1994) 2.34
In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J (1996) 2.33
Dependence of the mechanical properties of actin/alpha-actinin gels on deformation rate. Nature (1987) 2.31
DNA conformation, dynamics, and interactions in solution. Science (1982) 2.30
Climate forcings in the industrial era. Proc Natl Acad Sci U S A (1998) 2.29
The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities. Nature (2001) 2.23
Solid-phase synthesis of polynucleotides: V. Synthesis of oligodeoxyribonucleotides by the phosphomonotriazolide method. Nucleic Acids Symp Ser (1980) 2.20
Isolation of a cDNA clone for the murine transplantation antigen H-2Kb. Proc Natl Acad Sci U S A (1982) 2.20
Excellent outcome of allogeneic hematopoietic SCT with reduced-intensity conditioning for the treatment of chronic active EBV infection. Bone Marrow Transplant (2010) 2.05
Two mouse piwi-related genes: miwi and mili. Mech Dev (2001) 2.05
Comparison of recombinant human PTH(1-34) (LY333334) with a C-terminally substituted analog of human PTH-related protein(1-34) (RS-66271): In vitro activity and in vivo pharmacological effects in rats. J Bone Miner Res (1999) 2.05
Three-dimensional structures of free form and two substrate complexes of an extradiol ring-cleavage type dioxygenase, the BphC enzyme from Pseudomonas sp. strain KKS102. J Mol Biol (1996) 1.98
Deoxyadenosine-deoxycytidine pairing in the d(C-G-C-G-A-A-T-T-C-A-C-G) duplex: conformation and dynamics at and adjacent to the dA X dC mismatch site. Biochemistry (1984) 1.98
The use of synthetic oligodeoxyribonucleotides to produce specific deletions in the araBAD promoter of Escherichia coli B/r. Gene (1982) 1.98
Gene induction pathways mediated by distinct IRFs during viral infection. Biochem Biophys Res Commun (2001) 1.97
Eyelid reconstruction using a hard palate mucoperiosteal graft combined with a V-Y subcutaneously pedicled flap. Br J Plast Surg (2001) 1.96
CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer. Br J Cancer (2008) 1.93
Three-dimensional structure of a highly thermostable enzyme, 3-isopropylmalate dehydrogenase of Thermus thermophilus at 2.2 A resolution. J Mol Biol (1991) 1.92
Role of osteopontin in bone remodeling caused by mechanical stress. J Bone Miner Res (1999) 1.92
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Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing. Anal Chem (2001) 1.91
ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. Nature (2000) 1.89
Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity (1997) 1.89
Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies. Genes Cells (1996) 1.86
Value of Doppler ultrasound parameters of portal vein and hepatic artery in the diagnosis of cirrhosis and portal hypertension. Am J Gastroenterol (1997) 1.85
Angiopoietins 3 and 4: diverging gene counterparts in mice and humans. Proc Natl Acad Sci U S A (1999) 1.84
The p40x of human T-cell leukemia virus type I is a trans-acting activator of viral gene transcription. Jpn J Cancer Res (1985) 1.83
Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo. J Exp Med (1999) 1.82
Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eur J Clin Nutr (2010) 1.82