Published in J Exp Med on August 01, 1980
Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell (1991) 6.49
Genes of the major histocompatibility complex of the mouse. Annu Rev Immunol (1983) 4.44
Exon/intron organization and complete nucleotide sequence of an HLA gene. Proc Natl Acad Sci U S A (1982) 3.72
Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med (1991) 3.63
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell (1992) 3.11
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene. EMBO J (1995) 2.84
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction. Cell (1991) 2.83
Y-antigen killing by T cells of women is restricted by HLA. Nature (1977) 2.73
Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors. Mucosal Immunol (2012) 2.73
Regulation of TCR alpha and beta gene allelic exclusion during T-cell development. Immunol Today (1992) 2.71
Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation. N Engl J Med (1996) 2.63
The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur J Immunol (2000) 2.58
Human H-Y: a male-specific histocompatibility antigen derived from the SMCY protein. Science (1995) 2.55
A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter. Immunity (1997) 2.45
Crystal structure of a T cell receptor bound to an allogeneic MHC molecule. Nat Immunol (2000) 2.37
Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements. Nature (1986) 2.33
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature (1995) 2.15
Gene transfer of H-2 class II genes: antigen presentation by mouse fibroblast and hamster B-cell lines. Cell (1984) 2.12
The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. Science (1998) 2.11
Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes. Cell (1987) 2.00
Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin. Eur J Immunol (1989) 1.94
Identification of a graft versus host disease-associated human minor histocompatibility antigen. Science (1995) 1.87
Structural and genetic analyses of HLA class I molecules using monoclonal xenoantibodies. Tissue Antigens (1983) 1.87
Expression and function of transplantation antigens with altered or deleted cytoplasmic domains. Cell (1983) 1.86
Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex. Proc Natl Acad Sci U S A (1983) 1.78
The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition. Immunity (1997) 1.78
Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation. Nature (1992) 1.76
Family studies define a new histocompatibility locus, SB, between HLA-DR and GLO. Nature (1981) 1.72
Polyriboinosinic polyribocytidylic acid (poly(I:C)) induces stable maturation of functionally active human dendritic cells. J Immunol (1999) 1.68
H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity. J Exp Med (1992) 1.64
TCR/CD3 coupling to Fas-based cytotoxicity. J Exp Med (1995) 1.64
Are CD4 antibodies and peptide T new treatments for psoriasis? Lancet (1991) 1.62
Human cytotoxic T cell structures associated with expression of cytolysis. I. Analysis at the clonal cell level of the cytolysis-inhibiting effect of 7 monoclonal antibodies. Eur J Immunol (1982) 1.62
T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation. Eur J Immunol (1986) 1.62
CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes. J Exp Med (2001) 1.61
Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody. Eur J Immunol (1992) 1.58
Tissue distribution of human minor histocompatibility antigens. Ubiquitous versus restricted tissue distribution indicates heterogeneity among human cytotoxic T lymphocyte-defined non-MHC antigens. J Immunol (1992) 1.55
Characterization of T cell repertoire changes in acute Kawasaki disease. J Exp Med (1993) 1.51
Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition. Eur J Immunol (1991) 1.47
Essential role of CD8 palmitoylation in CD8 coreceptor function. J Immunol (2000) 1.46
Expression of specific cytolytic activity by H-2I region-restricted, influenza virus-specific T lymphocyte clones. J Exp Med (1985) 1.46
Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen. Immunol Rev (1991) 1.43
Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules. Eur J Immunol (1986) 1.39
Cutting edge: the HLA-A*0101-restricted HY minor histocompatibility antigen originates from DFFRY and contains a cysteinylated cysteine residue as identified by a novel mass spectrometric technique. J Immunol (1999) 1.38
A minor transplantation antigen detected by MHC-restricted cytotoxic T lymphocytes during graft-versus-host disease. Nature (1983) 1.34
Analysis of the expression and function of class-II major histocompatibility complex-encoded molecules by DNA-mediated gene transfer. Annu Rev Immunol (1986) 1.33
Modulation of surface T11 molecules induced by monoclonal antibodies: analysis of the functional relationship between antigen-dependent and antigen-independent pathways of human T cell activation. Eur J Immunol (1986) 1.33
Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen. Int Immunol (1992) 1.32
Engineered secreted T-cell receptor alpha beta heterodimers. Proc Natl Acad Sci U S A (1991) 1.30
Two distinct TL-like molecular subsets defined by monoclonal antibodies on the surface of human thymocytes with different expression on leukemia lines. Immunogenetics (1984) 1.30
Tyrosine-phosphorylated T cell receptor zeta chain associates with the actin cytoskeleton upon activation of mature T lymphocytes. Immunity (1995) 1.29
Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants. Eur J Immunol (1988) 1.29
Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation. J Exp Med (1994) 1.27
CD8 expression allows T cell signaling by monomeric peptide-MHC complexes. Immunity (1998) 1.27
Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34. Immunogenetics (1990) 1.26
Epitopic analysis of detergent-solubilized HLA molecules by solid-phase radioimmunoassay. J Immunol Methods (1982) 1.25
Expression of I-Ak class II genes in mouse L cells after DNA-mediated gene transfer. Nature (1983) 1.25
Anti-CD2 (sheep red blood cell receptor) monoclonal antibodies and T cell activation. I. Pairs of anti-T11.1 and T11.2 (CD2 subgroups) are strongly mitogenic for T cells in presence of 12-O-tetradecanoylphorbol 13-acetate. Eur J Immunol (1986) 1.25
Cell-mediated lympholysis studies in renal allograft recipients. Transplantation (1981) 1.25
Dynamic adhesion of CD8-positive cells to antibody-coated surfaces: the initial step is independent of microfilaments and intracellular domains of cell-binding molecules. J Cell Biol (1994) 1.24
Ia-transfected L-cell fibroblasts present a lysozyme peptide but not the native protein to lysozyme-specific T cells. Proc Natl Acad Sci U S A (1985) 1.21
Alloimmunity to human H-Y. Lancet (1976) 1.20
The 21- and 23-kD forms of TCR zeta are generated by specific ITAM phosphorylations. Nat Immunol (2000) 1.20
Rejection of bone-marrow graft by recipient-derived cytotoxic T lymphocytes against minor histocompatibility antigens. Lancet (1990) 1.19
Genomic identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR. Tissue Antigens (1998) 1.18
Cotransfer of the Ed alpha and Ad beta genes into L cells results in the surface expression of a functional mixed-isotype Ia molecule. Proc Natl Acad Sci U S A (1986) 1.17
Monoclonal antibodies raised against engineered soluble mouse T cell receptors and specific for V alpha 8-, V beta 2- or V beta 10-bearing T cells. Eur J Immunol (1991) 1.16
A signaling role for the cytoplasmic segment of the CD8 alpha chain detected under limiting stimulatory conditions. Proc Natl Acad Sci U S A (1990) 1.16
A 55,000 Mr surface antigen on activated human T lymphocytes defined by a monoclonal antibody. Hum Immunol (1983) 1.14
The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein. J Immunol (2001) 1.14
Genomic organization of the mouse T cell receptor V alpha family. EMBO J (1990) 1.13
Homeotic control in Drosophila; the scabrous gene is an in vivo target of Ultrabithorax proteins. EMBO J (1992) 1.12
The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. EMBO J (1997) 1.12
Cytokines restore MHC class I complex formation and control antigen presentation in human cytomegalovirus-infected cells. J Gen Virol (1995) 1.12
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding. J Exp Med (1996) 1.11
Specific Th1 cytokine down-regulation associated with primary clinically derived human immunodeficiency virus type 1 Nef gene-induced expression. J Immunol (1996) 1.11
Anti-self HLA may be clonally expressed. J Exp Med (1979) 1.10
Immunogenetics of human minor histocompatibility antigens: their polymorphism and immunodominance. Immunogenetics (1992) 1.10
Prolonged IL-2 receptor alpha/CD25 expression after T cell activation via the adhesion molecules CD2 and CD28. Demonstration of combined transcriptional and post-transcriptional regulation. J Immunol (1992) 1.09
Recognition of minor histocompatibility antigens on lymphocytic and myeloid leukemic cells by cytotoxic T-cell clones. Blood (1994) 1.08
Clonal analysis of human T cell activation by the Mycoplasma arthritidis mitogen (MAS). Eur J Immunol (1988) 1.08
Natural and engineered disorders of lymphocyte development. Science (1998) 1.07
Double-negative thymocyte subsets in CD3 zeta chain-deficient mice: absence of HSA+CD44-CD25- cells. Eur J Immunol (1994) 1.07