Published in Vet Med Small Anim Clin on July 01, 1981
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Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine. J Med Chem (1980) 1.41
Treatment of experimental herpes simplex keratitis with acycloguanosine. Br J Ophthalmol (1979) 1.36
Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica. J Org Chem (1973) 1.32
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Metabolism of trimethoprim in man and measurement of a new metabolite: a new fluorescence assay. J Infect Dis (1973) 1.09
2,4-Diamino-5-benzylpyrimidines and analogues as antibacterial agents. 5. 3',5'-Dimethoxy-4'-substituted-benzyl analogues of trimethoprim. J Med Chem (1981) 1.05
Identification of Glu340 as the active-site nucleophile in human glucocerebrosidase by use of electrospray tandem mass spectrometry. J Biol Chem (1994) 1.02
Human alpha-galactosidase A: glycosylation site 3 is essential for enzyme solubility. Biochem J (1998) 1.02
The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica. J Org Chem (1975) 1.00
Enzyme augmentation in moderate to life-threatening Gaucher disease. Pediatr Res (1992) 0.99
Structure and stereochemistry of jatrophone, a novel macrocyclic diterpenoid tumor inhibitor. J Am Chem Soc (1976) 0.97
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Discrepancy between the antibacterial activities and the inhibitory effects on Micrococcus luteus DNA gyrase of 13 quinolones. Chemotherapy (1986) 0.95
Relationship of ochratoxin A to foetal death in laboratory and domestic animals. Nature (1971) 0.92
Preclinical biochemical pharmacology and toxicology of piritrexim, a lipophilic inhibitor of dihydrofolate reductase. NCI Monogr (1987) 0.89
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Pharmacokinetics of trimethoprim and sulfadiazine in the dog: urine concentrations after oral administration. Am J Vet Res (1981) 0.88
Gaucher disease: four rare alleles encoding F213I, P289L, T323I, and R463C in type 1 variants. Hum Mutat (1992) 0.87
Type 1 Gaucher disease presenting with extensive mandibular lytic lesions: identification and expression of a novel acid beta-glucosidase mutation. Am J Med Genet (1999) 0.85
Metabolism and disposition by the rat of 35S-sulfadiazine alone and in the presence of trimethoprim. Drug Metab Dispos (1979) 0.85
Expression of functional human acid beta-glucosidase in COS-1 and Spodoptera frugiperda cells. Enzyme (1989) 0.84
Elimination of antibiotic-resistant plasmids by quinolone antibiotics. Chemotherapy (1988) 0.81
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Preclinical toxicology studies with acyclovir: acute and subchronic tests. Fundam Appl Toxicol (1984) 0.80
Interaction of clavulanic acid, sulbactam and cephamycin antibiotics with beta-lactamases. Drugs Exp Clin Res (1987) 0.80
Datiscacin, a novel cytotoxic cucurbitacin 20-acetate from Datisca glomerata. J Org Chem (1973) 0.79
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Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. Biochem Pharmacol (1991) 0.78
Diffusion of trimethoprim and sulfamethoxazole from susceptibility disks into agar medium. Antimicrob Agents Chemother (1975) 0.78
Myoclonus from selective dentate nucleus degeneration in type 3 Gaucher disease. Arch Neurol (2000) 0.77
Serum concentrations of trimethoprim and sulfadiazine following oral paste administration to the horse. Am J Vet Res (1981) 0.77
Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase. Biochim Biophys Acta (1973) 0.77
A kinetic study of the ninhydrin reaction. Biochemistry (1966) 0.76
Eighteen month oral study of aspirin, phenacetin and caffeine, in C57Bl/6 mice. Drug Chem Toxicol (1980) 0.76
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Use of 1-H nuclear magnetic resonance spectroscopy for sequence and configuration analysis of cyclic tetrapeptides. The structure of Tentoxin-1,2a--d. J Am Chem Soc (1975) 0.75
Specific TLC determination of trimethoprim and sulfamethoxazole in plasma. J Pharm Sci (1974) 0.75
Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83. Drug Metab Dispos (1993) 0.75
Development of pharmacokinetic models for sulfonamides in food animals: metabolic depletion profile of sulfadiazine in the calf. Am J Vet Res (1982) 0.75
The relation of pesticides to abortion in dairy cattle. J Am Vet Med Assoc (1971) 0.75
Disseminated malignant lymphoma in a bovine fetus. Cornell Vet (1971) 0.75
Specific TLC tissue residue determination of sulfadiazine following fluorescamine derivatization. J Pharm Sci (1975) 0.75
Evaluating the rat inner ear. A technique using scanning electron microscopy. Arch Otolaryngol (1980) 0.75
Effect of AHR-5333 on flea antigen extract-induced skin reactions in flea-allergic dogs. J Vet Pharmacol Ther (1988) 0.75
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. Cancer Treat Rep (1982) 0.75
Experimental induction of Proteus mirabilis cystitis in the pony and evaluation of therapy with trimethoprim-sulfadiazine. Am J Vet Res (1981) 0.75
The disposition and metabolism of [14C]piritrexim in dogs after intravenous and oral administration. Drug Metab Dispos (1992) 0.75
Preclinical toxicology studies with acyclovir: ophthalmic and cutaneous tests. Fundam Appl Toxicol (1984) 0.75
A new fluorescence assay of trimethoprim and metabolites using quantitative thin-layer chromatography. J Chromatogr (1973) 0.75
Datiscoside, a novel antileukemic cucurbitacin glycoside from Datisca glomerata. J Am Chem Soc (1972) 0.75
Metabolic fates of N-methyl- -phenylsuccinimide (phensuximide, milontin) and of -phenylsuccinimide in the dog. J Pharmacol Exp Ther (1972) 0.75
Drug safety: phenacetin. Science (1979) 0.75
The role of dietary nitrate and nitrite in the reductive deamination of sulfadiazine by the rat, guinea pig, and neonatal calf. Life Sci (1982) 0.75
Identification of trimethoprim 3-oxide as a new urinary metabolite of trimethoprim in man. J Pharm Sci (1973) 0.75
Competitive protein binding assay for piritrexim. J Pharm Sci (1989) 0.75
Questions study design. J Am Vet Med Assoc (1985) 0.75
Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat. Drug Metab Dispos (1991) 0.75
Tumor inhibitors. 33. Cytotoxic flavones from eupatorium species. Tetrahedron (1969) 0.75
II. Novel deaminated sulfadiazine metabolites in neonatal calf tissue, plasma, and urine following oral treatment of 14C-sulfadiazine. Life Sci (1980) 0.75
The disposition and metabolism of [14C]piritrexim in rats after intravenous and oral administration. Drug Metab Dispos (1991) 0.75
Concerning toxicity testing of atracurium. Anesthesiology (1985) 0.75
Phenacetin safety. Science (1980) 0.75