Published in J Pharm Sci on June 01, 1975
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The isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica. J Org Chem (1975) 1.00
Micro procedure for determination of pyrophosphate and orthophosphate. Anal Biochem (1970) 0.98
Structure and stereochemistry of jatrophone, a novel macrocyclic diterpenoid tumor inhibitor. J Am Chem Soc (1976) 0.97
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Modulation of hematoporphyrin derivative-sensitized phototherapy with corynebacterium parvum in murine transitional cell carcinoma. Urology (1989) 0.91
Utilization of dihydroflavin mononucleotide and superoxide anion for the decyclization of L-tryptophan by murine epididymal indoleamine 2,3-dioxygenase. Arch Biochem Biophys (1987) 0.91
High-performance liquid chromatographic assay for the simultaneous measurement of trimethoprim and sulfamethoxazole in plasma or urine. Ther Drug Monit (1990) 0.89
Survey of antenatal women's knowledge of maternal and fetal risks of tobacco smoking and acceptability of nicotine replacement products in pregnancy. J Obstet Gynaecol (2005) 0.89
Preclinical biochemical pharmacology and toxicology of piritrexim, a lipophilic inhibitor of dihydrofolate reductase. NCI Monogr (1987) 0.89
Pharmacokinetics of trimethoprim and sulfadiazine in the dog: urine concentrations after oral administration. Am J Vet Res (1981) 0.88
A phase I clinical and pharmacological study of weekly intravenous infusions of piritrexim (BW301U). Eur J Cancer Clin Oncol (1989) 0.88
Effects of aerosolized synthetic surfactant, atovaquone, and the combination of these on murine Pneumocystis carinii pneumonia. J Infect Dis (1998) 0.88
Elevation of brain histamine levels by diaminopyrimidine inhibitors of histamine N-methyl transferase. Biochem Pharmacol (1978) 0.87
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Inhibition of histamine-metabolizing enzymes and elevation of histamine levels in tissues by lipid-soluble anticancer folate antagonists. Mol Pharmacol (1980) 0.86
Metabolism and disposition by the rat of 35S-sulfadiazine alone and in the presence of trimethoprim. Drug Metab Dispos (1979) 0.85
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Mammalian deoxyuridine 5'-triphosphate pyrophosphatase. Biochim Biophys Acta (1971) 0.84
A sensitive high-performance liquid chromatographic-fluorometric assay for dihydrofolate reductase in adult rat brain, using 7,8-dihydrobiopterin as substrate. Anal Biochem (1984) 0.83
A robotics-based liquid chromatographic assay for the measurement of atovaquone in plasma. J Pharm Biomed Anal (1995) 0.83
Effects of pregnancy on several cortisol-responsive enzymes in rat liver. Am J Physiol (1966) 0.83
Quantitative thin-layer chromatography of pyrimethamine and related diaminopyrimidines in body fluids and tissues. J Chromatogr (1975) 0.82
Antitumor phthalanilides active in acute and chronic Trypanosoma brucei brucei murine infections. Am J Trop Med Hyg (1984) 0.82
Two new tetrahydropterin intermediates in the adrenal medullary de novo biosynthesis of tetrahydrobiopterin. Biochem Biophys Res Commun (1984) 0.81
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Superiority of intralesional immunotherapy with Corynebacterium parvum and Allium sativum in control of murine transitional cell carcinoma. J Urol (1986) 0.81
Inhibition of ribosephosphate pyrophosphokinase activity by decoinine, an adenine nucleoside. Biochem Biophys Res Commun (1964) 0.80
Regulation of guanosine triphosphate cyclohydrolase and tetrahydrobiopterin levels and the role of the cofactor in tyrosine hydroxylation in primary cultures of adrenomedullary chromaffin cells. J Neurochem (1986) 0.80
Regulation of tetrahydrobiopterin biosynthesis in cultured adrenal cortical tumor cells by adrenocorticotropin and adenosine 3',5'-cyclic monophosphate. Endocrinology (1986) 0.80
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Synthesis, utilization, and structure of the tetrahydropterin intermediates in the bovine adrenal medullary de novo biosynthesis of tetrahydrobiopterin. J Biol Chem (1986) 0.79
Metabolic disposition and pharmacokinetics of [14C]-amprenavir, a human immunodeficiency virus type 1 (HIV-1) protease inhibitor, administered as a single oral dose to healthy male subjects. J Clin Pharmacol (2001) 0.79
Differences in the metabolism of the aromatic amino acid hydroxylase cofactor, tetrahydrobiopterin, in mutant mice with neurological and immunological defects. Biochem Genet (1986) 0.79
Tetrahydrobiopterin is synthesized by separate pathways from dihydroneopterin triphosphate and from sepiapterin in adrenal medulla preparations. Arch Biochem Biophys (1983) 0.79
Datiscacin, a novel cytotoxic cucurbitacin 20-acetate from Datisca glomerata. J Org Chem (1973) 0.79
Tumor inhibitors. LXV. Bersenogenin, berscillogenin, and 3-epiberscillogenin, three new cytotoxic bufadienolides from Bersama abyssinica. J Org Chem (1971) 0.79
Inhibitors of histamine metabolism in vitro and in vivo. Correlations with antitrypanosomal activity. Biochem Pharmacol (1984) 0.79
Pharmacokinetics: selectivity of action related to physicochemical properties and kinetic patterns of anticancer drugs. Cancer (1977) 0.79
The manipulation of metabolism by drugs and nutrients. Cancer Res (1969) 0.79
Diffusion of trimethoprim and sulfamethoxazole from susceptibility disks into agar medium. Antimicrob Agents Chemother (1975) 0.78
Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. Biochem Pharmacol (1991) 0.78
Prevention by polyamines of the curative effect of amicarbalide and imidocarb for Trypanosoma brucei infections in mice. Biochem Pharmacol (1981) 0.78
Evaluation of combination chemotherapy in vivo and in culture with l- -D-arabinofuranosylcytosine and 1-formylisoquinoline thiosemicarbazone. Cancer Res (1972) 0.78
Baquiloprim, a new antifolate antibacterial: in vitro activity and pharmacokinetic properties in cattle. Res Vet Sci (1993) 0.78
Cranial isotopic section scanning. Clin Radiol (1977) 0.78
Hormonal regulation of guanosine triphosphate cyclohydrolase activity and biopterin levels in the rat adrenal cortex. Endocrinology (1983) 0.77
Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase. Biochim Biophys Acta (1973) 0.77
Serum concentrations of trimethoprim and sulfadiazine following oral paste administration to the horse. Am J Vet Res (1981) 0.77
Synthesis and biological activity of some new N6-substituted purine nucleosides. J Med Chem (1969) 0.77
Methapyrilene is a genotoxic carcinogen: studies on methapyrilene and pyrilamine in the L5178Y/TK +/- mouse lymphoma assay. Mutat Res (1987) 0.76
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A kinetic study of the ninhydrin reaction. Biochemistry (1966) 0.76
Studies on the nature and specificity of the induction of several adaptive enzymes responsive to cortisol. Adv Enzyme Regul (1964) 0.76
Determination of biopterin and other pterins in tissues and body fluids by high-performance liquid chromatography. J Chromatogr (1983) 0.76
The pharmacokinetics of 1954U89, 1,3-diamino-7-(1-ethylpropyl)-8-methyl-7H-pyrrolo-(3,2-f)quinazoline, in dogs and rats after intravenous and oral administration. Biopharm Drug Dispos (1997) 0.76
Use of 1-H nuclear magnetic resonance spectroscopy for sequence and configuration analysis of cyclic tetrapeptides. The structure of Tentoxin-1,2a--d. J Am Chem Soc (1975) 0.75
Lipid-soluble diaminopyrimidine inhibitors of dihydrofolate reductase. Cancer Treat Rep (1977) 0.75
The role of dietary nitrate and nitrite in the reductive deamination of sulfadiazine by the rat, guinea pig, and neonatal calf. Life Sci (1982) 0.75
Competitive protein binding assay for piritrexim. J Pharm Sci (1989) 0.75
Disposition, metabolism, and excretion of the anticancer agent crisnatol in the rat. Drug Metab Dispos (1991) 0.75
Cerebral scintigraphy with a Nuclear Chicago 1206 high performance gamma camera. Br J Radiol (1974) 0.75
The disposition and metabolism of [14C]piritrexim in dogs after intravenous and oral administration. Drug Metab Dispos (1992) 0.75
Biosynthesis of tetrahydrobiopterin in the presence of dihydrofolate reductase inhibitors. Mol Pharmacol (1983) 0.75
Antitumor effects of methylglyoxal-bis(N-4-methylthiosemicarbazone) and their potentiation in pyridoxine-deficient animals. Cancer Res (1965) 0.75
The disposition and metabolism of [14C]piritrexim in rats after intravenous and oral administration. Drug Metab Dispos (1991) 0.75
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model. Cancer Treat Rep (1982) 0.75
Experimental induction of Proteus mirabilis cystitis in the pony and evaluation of therapy with trimethoprim-sulfadiazine. Am J Vet Res (1981) 0.75
Trimethoprim and sulfadiazine concentrations in aqueous and vitreous humors of the dog. Vet Med Small Anim Clin (1981) 0.75
Kethoxal bis(thiosemicarbazone). I. Effects against experimental tumors. Cancer Res (1965) 0.75
Development of pharmacokinetic models for sulfonamides in food animals: metabolic depletion profile of sulfadiazine in the calf. Am J Vet Res (1982) 0.75
An evaluation of static cerebral studies with a nuclear data (Selektronik) radicamera II. Br J Radiol (1973) 0.75
Pharmacokinetics and disposition in the rat of a DNA intercalator 502U83. Drug Metab Dispos (1993) 0.75