Published in Nature on December 24, 1981
In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. J Exp Med (1984) 6.27
Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens. J Exp Med (1985) 2.79
Phenotype, specificity, and function of T cell subsets and T cell interactions involved in skin allograft rejection. J Exp Med (1987) 1.67
Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified self. J Exp Med (1985) 1.57
Allogeneic tumor rejection induced by the intravenous injection of Lyt-2+ cytolytic T lymphocyte clones. J Exp Med (1982) 1.54
Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med (1987) 1.41
Characterization of two distinct primary T cell populations that secrete interleukin 2 upon recognition of class I or class II major histocompatibility antigens. J Exp Med (1986) 1.29
Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers. J Exp Med (1982) 1.22
Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation. J Exp Med (1996) 1.16
An antigen receptor-driven, interleukin 2-independent pathway for proliferation of murine cytolytic T lymphocyte clones. J Exp Med (1986) 1.12
Evidence for involvement of dual-function T cells in rejection of MHC class I disparate skin grafts. Assessment of MHC class I alloantigens as in vivo helper determinants. J Exp Med (1988) 1.10
Interleukin-4 diminishes CD8(+) respiratory syncytial virus-specific cytotoxic T-lymphocyte activity in vivo. J Virol (1999) 1.05
Activity of CD4+ T-cell clones of type 1 and type 2 in generation of influenza virus-specific cytotoxic responses in vitro. J Virol (1991) 1.04
Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implications for marrow transplantation in humans. J Exp Med (1993) 1.01
Characteristics and functions of Sendai virus-specific T-cell clones. J Virol (1984) 0.97
Helper cell-independent cytotoxic clones in man. J Exp Med (1982) 0.95
The selective ablation of interleukin 2-producing cells isolated from transgenic mice. J Exp Med (1993) 0.91
Human double-negative (CD4-CD8-) T cells bearing alpha beta T cell receptor possess both helper and cytotoxic activities. Clin Exp Immunol (1991) 0.86
Helper T cells for cytotoxic T lymphocytes need not be I region restricted. J Exp Med (1982) 0.84
Augmentation of cell-mediated responses in vitro by a monoclonal anti-helper factor antibody. Immunology (1985) 0.80
Primed lymphocyte testing specificity of alloreactive lymphocyte clones for HLA-B locus determinants. Proc Natl Acad Sci U S A (1983) 0.78
T cells can be cytotoxic without making interleukin 2: a model of separate pathways of induction. Proc Natl Acad Sci U S A (1986) 0.77
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med (1997) 8.65
One-way stimulation in mixed leukocyte cultures. Science (1966) 6.62
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med (2000) 6.32
Histocompatibility matching. VI. Miniaturization of the mixed leukocyte culture test: a preliminary report. Transplantation (1971) 5.43
Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse. J Exp Med (1972) 4.59
Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells. Proc Natl Acad Sci U S A (1980) 4.35
Differential function of major histocompatibility complex antigens in T-lymphocyte activation. Nature (1976) 3.87
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science (1988) 3.56
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med (2000) 3.41
The involvement of LD- and SD-region differences in MLC and CML: a three-cell experiment. Transplant Proc (1973) 3.35
Precipitation of radioactively labeled samples: a semi-automatic multiple-sample processor. Cell Immunol (1972) 3.35
Cell-mediated lympholysis. Importance of serologically defined H-2 regions. J Exp Med (1973) 3.34
Hu-1: Major histocompatibility locus in man. Science (1967) 3.13
Cell mediated immunity: separation of cells involved in recognitive and destructive phases. Science (1973) 3.04
Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J Immunol (1993) 3.03
Phenotypic expressions of the major histocompatibility locus in man (HL-A): leukocyte antigens and mixed leukocyte culture reactivity. J Exp Med (1968) 3.00
Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings. J Clin Oncol (1997) 2.79
Identification and characterization of CD39/vascular ATP diphosphohydrolase. J Biol Chem (1996) 2.79
Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B. EMBO J (1993) 2.75
Detection of a novel human class II HLA antigen. Nature (1983) 2.61
Expression of heme oxygenase-1 can determine cardiac xenograft survival. Nat Med (1998) 2.40
Genetic and immunological complexity of major histocompatibility regions. Science (1972) 2.40
Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses. Proc Natl Acad Sci U S A (1992) 2.37
Quantitation and cloning of cytolytic T lymphocytes and their precursors. Immunol Rev (1980) 2.32
Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome. Lancet (1968) 2.29
A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism. J Biol Chem (1996) 2.26
DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J Exp Med (1991) 2.14
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J Exp Med (1990) 2.12
Effect of IL-7 on the growth of fetal thymocytes in culture. J Immunol (1989) 2.11
Influence of a recombinant human soluble tumor necrosis factor receptor FC fusion protein on type II collagen-induced arthritis in mice. J Immunol (1993) 2.02
Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes. J Exp Med (1974) 2.01
Transplantation of discordant xenografts: a review of progress. Immunol Today (1990) 2.00
A miniaturized mouse mixed leukocyte culture in serum-free and mouse serum supplemented media. J Immunol Methods (1973) 1.97
Lymphocyte reactivity in vitro. I. Cellular reconstitution of purified lymphocyte response. Cell Immunol (1970) 1.97
The major histocompatibility complex--genetics and biology. (First of three parts). N Engl J Med (1976) 1.92
HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes. Science (1975) 1.91
Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol (2001) 1.89
Antigenic requirements for triggering of cytotoxic T lymphocytes. Immunol Rev (1977) 1.82
Sequence polymorphism of HLA DR beta 1 alleles relating to T-cell-recognized determinants. Nature (1985) 1.82
Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor. Nature (1987) 1.75
Lymphocyte reactivity in vitro. II. Soluble reconstituting factor permitting response of purified lymphocyte. Cell Immunol (1970) 1.74
Allogeneic and xenogeneic response in mixed leukocyte cultures. J Exp Med (1972) 1.70
Five HLA-D clusters associated with HLA-DR4. Hum Immunol (1982) 1.70
Generation of cytotoxic lymphocytes in vitro against autologous human leukaemia cells. Nature (1976) 1.64
Specificity of allogeneic cell recognition by human lymphocytes in vitro. Science (1971) 1.62
Loss of ATP diphosphohydrolase activity with endothelial cell activation. J Exp Med (1997) 1.62
Cell kinetic studies in mixed leukocyte cultures: an in vitro model of homograft reactivity. Proc Natl Acad Sci U S A (1969) 1.61
Lymphocyte studies in congenital thymic dysplasia: The one-way stimulation test. J Pediatr (1968) 1.59
The molecular basis of alloreactivity. Immunol Today (1990) 1.56
Use of HLA loss mutants to analyse the structure of the human major histocompatibility complex. Nature (1982) 1.56
Mouse cell-mediated lympholysis assay in serum-free and mouse serum-supplemented media: culture conditions and genetic factors. Scand J Immunol (1975) 1.55
Genetic control of cell-mediated lympholysis in mouse. J Exp Med (1974) 1.51
TCGF production for cloning and growth of functional human T lymphocytes. Scand J Immunol (1980) 1.50
Regulation of T cell proliferation by IL-7. J Immunol (1990) 1.50
Alternative pathways of T lymphocyte activation. J Exp Med (1978) 1.49
Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B. J Exp Med (1996) 1.49
Call for moratorium on xenotransplants. Nature (1998) 1.48
Specificity of antigen recognition by human lymphocytes in vitro. Science (1970) 1.48
Continuous culture of T cells cytotoxic for autologous human leukaemia cells. Nature (1979) 1.46
Lymphocyte reactivity to serologically undetected components of the major histocompatibility complex. Nat New Biol (1973) 1.44
Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation. Diabetes (2001) 1.43
Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury. FASEB J (2003) 1.42
Dw/LD-related molecular polymorphism of DR4 beta-chains. J Exp Med (1983) 1.42
Human mixed lymphocyte cultures. Evaluation of a microculture technique utilizing the Multiple Automated Sample Harvester (MASH). Clin Exp Immunol (1973) 1.41
Generation of cytotoxic T lymphocytes to autologous human leukaemia cells by sensitisation to pooled allogeneic normal cells. Nature (1978) 1.41
SB: a new HLA-linked human histocompatibility gene defined using HLA-mutant cell lines. Nature (1981) 1.40
IL-1 and its receptor are translocated to the nucleus. J Immunol (1990) 1.32
Human lymphocytes recognise mouse alloantigens. Nature (1975) 1.31
Glucocorticoid-mediated repression of NFkappaB activity in endothelial cells does not involve induction of IkappaBalpha synthesis. J Biol Chem (1996) 1.30
Interleukin 7 enhances cytolytic T lymphocyte generation and induces lymphokine-activated killer cells from human peripheral blood. J Exp Med (1990) 1.30
Transplantation: pairing of donor and recipient. Science (1970) 1.28
The major histocompatibility complex - genetics and biology (third of three parts). N Engl J Med (1976) 1.28
A20 inhibits NF-kappaB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis. Blood (1998) 1.27
Long-term growth of lymphokine-activated killer (LAK) cells: role of anti-CD3, beta-IL 1, interferon-gamma and -beta. J Immunol (1987) 1.26
Cytotoxicity: specificity after in vitro sensitization. Science (1970) 1.26
Regulation of the tissue factor promoter in endothelial cells. Binding of NF kappa B-, AP-1-, and Sp1-like transcription factors. J Biol Chem (1995) 1.26
Thymic transplantation in a case of chronic mucocutaneous candidiasis. Lancet (1971) 1.26
Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor. Science (1990) 1.25
NK-kappa B subunit-specific regulation of the I kappa B alpha promoter. J Biol Chem (1994) 1.24
Specificity of cell-mediated lympholysis for public and private H-2 determinants. Scand J Immunol (1975) 1.24
Immunopathology of hyperacute xenograft rejection in a swine-to-primate model. Transplantation (1991) 1.24
Release of heparan sulfate from endothelial cells. Implications for pathogenesis of hyperacute rejection. J Exp Med (1990) 1.23
Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts. J Exp Med (1990) 1.23
The Steel factor. Dev Biol (1992) 1.23
A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets. J Exp Med (1999) 1.22
Genetic control of mixed leukocyte culture reactivity. Transplant Rev (1972) 1.21
Abrogation of cytotoxicity of mixed leukocyte cultures. Transplant Proc (1972) 1.21
Lysis of leukemia cells by spleen cells of normal mice. Proc Natl Acad Sci U S A (1975) 1.20
Recombinant soluble murine IL-4 receptor can inhibit or enhance IgE responses in vivo. J Immunol (1993) 1.20
OKT4+ cytotoxic T cells can lyse targets via class I molecules and can be blocked by monoclonal antibody against T4 molecules. J Immunol (1984) 1.18
Genetic and cellular aspects of xenogeneic mixed leukocyte culture reaction. J Exp Med (1976) 1.16
Helper cell-independent cytolytic T lymphocytes specific for a minor histocompatibility antigen. J Immunol (1983) 1.15
Isolation and characterization of NK cell or NK/T cell-specific cDNA clones. J Mol Cell Immunol (1990) 1.14