Cell mediated immunity: separation of cells involved in recognitive and destructive phases.

T-T-cell interactions during the vitro cytotoxic allograft responses. I. Soluble products from activated Lyl+ T cells trigger autonomously antigen-primed Ly23+ T cells to cell proliferation and cytolytic activity. J Exp Med (1978) 3.69

Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursors. J Exp Med (1977) 3.30

Synergism between subpopulations of thymus-derived cells mediating the proliferative and effector phases of the mixed lymphocyte reaction. Proc Natl Acad Sci U S A (1973) 2.48

Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain. J Exp Med (1975) 2.39

Regulatory mechanisms in cell-mediated immune responses. I. Regulation of mixed lymphocyte reactions by alloantigen-activated thymus-derived lymphocytes. J Exp Med (1974) 2.26

Effects on C-reactive protein on the lymphoid system. I. Binding to thymus-dependent lymphocytes and alteration of their functions. J Exp Med (1975) 2.17

The mediator of cellular immunity. VII. Localization of sensitized lymphocytes in inflammatory exudates. J Exp Med (1974) 2.05

Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes. J Exp Med (1974) 2.01

Allogeneic carrier-specific enhancement of hapten-specific secondary B-cell responses. J Exp Med (1976) 1.87

The effect of 2-mercaptoethanol on murine mixed lymphocyte cultures. J Exp Med (1974) 1.52

Alternative pathways of T lymphocyte activation. J Exp Med (1978) 1.49

Separation of helper and suppressor T lymphocytes on a ficoll velocity sedimentation gradient. J Exp Med (1976) 1.36

Immunoregulatory T cell circuits in man. Alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic stimulus. J Exp Med (1983) 1.30

Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants. J Exp Med (1976) 1.30

Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses. J Exp Med (1982) 1.20

Human T-cell heterogeneity as delineated with a specific human thymus lymphocyte antiserum. In vitro effects on mitogen response mixed leukocyte culture, cell-mediated lymphocytotoxicity, and lymphokine production. J Clin Invest (1975) 1.16

Concanavalin A-mediated activation of antigen-primed lymphocytes into secondary cytotoxic lymphocytes. J Exp Med (1977) 1.13

Recognitive specificity of human cytotoxic T lymphocytes. I. Antigen-specific inhibition of human cell-mediated lympholysis. J Exp Med (1975) 1.11

Secondary cell-mediated lympholysis: importance of H-2 LD and SD factors. J Exp Med (1976) 1.07

Private specificities of H-2K and H-2D loci as possible selective targets for effector lymphocytes in cell-mediated immunity. J Exp Med (1975) 1.04

Cell-mediated immunity: differential maturation of mixed leukocyte reaction and cell-mediated lympholysis. J Exp Med (1975) 0.95

Helper cell-independent cytotoxic clones in man. J Exp Med (1982) 0.95

Differential effects of chlorpromazine on the in vitro generation and effector function of cytotoxic lymphocytes. J Exp Med (1976) 0.94

Serological distinction of mutants B6.CH(zl) and B6.M505 from strain C57BL-6. J Exp Med (1974) 0.92

Functional T cells in rabbits gut mucosal lymphocytes. Gut (1976) 0.90

Alloantiserum-induced inhibition of migration inhibition factor production in immune response gene-controlled immune systems. J Exp Med (1974) 0.89

The differentiation pathway of T lymphocytes. Evidence for two differentiated cell types. J Exp Med (1974) 0.85

Generation of cytotoxic effector cells by immunocompetent thymus cell subpopulations. J Exp Med (1977) 0.83

Cell-mediated lympholysis in vitro. Independence of mixed lymphocyte reactions and T-cell mitogen responses from the in vitro generation of cytotoxic effectors in primary immunodeficiency diseases. Clin Exp Immunol (1975) 0.83

Specific elimination of cytotoxic effector cells. I. Adsorptive behavior of effectors and their precursors and spleen cell monolayers. J Exp Med (1976) 0.82

Blastogenic suppression and alloantibody activity of sera from renal allograft recipients. J Clin Invest (1974) 0.81

Heterogeneity in the development of cytotoxic T lymphocytes in vitro revealed by sensitivity to hydrocortisone. J Exp Med (1975) 0.80

Immunological tolerance. Dissociation between in vivo and in vitro reactivity in parabiosed mice. J Exp Med (1974) 0.80

Binding of thyroid microsomes by lymphocytes from patients with thyroid disease and normal subjects. Clin Exp Immunol (1976) 0.79

Cell-mediated immune responses between HLA-identical siblings: recognition of antigenic changes associated with acute myelogenous leukaemia. Clin Exp Immunol (1980) 0.78

Investigation of the mechanism of active enhancement of renal allograft survival by blood transfusion. Immunology (1988) 0.77

The effect of membrane stabilizing agents on induction of the immune response. I. Effect of lymphocyte activation in mixed lymphocyte reactions. J Exp Med (1976) 0.77

The relation between the T cells responsible for cell-mediated cytotoxic killing of mastocytoma cells and the helper-cell effect. Immunology (1975) 0.75

Cellular basis of neonatal induction of in vitro tolerance. J Exp Med (1976) 0.75

Graft-versus-leukemia reactions after bone marrow transplantation. Blood (1990) 7.11

Evidence for transcriptional regulation of orotidine-5'-phosphate decarboxylase in yeast by hybridization of mRNA to the yeast structural gene cloned in Escherichia coli. Proc Natl Acad Sci U S A (1979) 6.81

One-way stimulation in mixed leukocyte cultures. Science (1966) 6.62

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med (2000) 6.32

Immune responses in vitro. I. Culture conditions for antibody synthesis. Cell Immunol (1972) 6.04

Histocompatibility matching. VI. Miniaturization of the mixed leukocyte culture test: a preliminary report. Transplantation (1971) 5.43

Serologically defined and lymphocyte-defined components of the major histocompatibility complex in the mouse. J Exp Med (1972) 4.59

Gamma ray-induced loss of expression of HLA and glyoxalase I alleles in lymphoblastoid cells. Proc Natl Acad Sci U S A (1980) 4.35

Differential function of major histocompatibility complex antigens in T-lymphocyte activation. Nature (1976) 3.87

Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med (2000) 3.41

The involvement of LD- and SD-region differences in MLC and CML: a three-cell experiment. Transplant Proc (1973) 3.35

Precipitation of radioactively labeled samples: a semi-automatic multiple-sample processor. Cell Immunol (1972) 3.35

Cell-mediated lympholysis. Importance of serologically defined H-2 regions. J Exp Med (1973) 3.34

Hu-1: Major histocompatibility locus in man. Science (1967) 3.13

Methodological concerns and recommendations on policy consequences of the World Health Report 2000. Lancet (2001) 3.04

Phenotypic expressions of the major histocompatibility locus in man (HL-A): leukocyte antigens and mixed leukocyte culture reactivity. J Exp Med (1968) 3.00

Results of allogeneic bone marrow transplants for leukemia using donors other than HLA-identical siblings. J Clin Oncol (1997) 2.79

Identification and characterization of CD39/vascular ATP diphosphohydrolase. J Biol Chem (1996) 2.79

Cytokine-inducible expression in endothelial cells of an I kappa B alpha-like gene is regulated by NF kappa B. EMBO J (1993) 2.75

Detection of a novel human class II HLA antigen. Nature (1983) 2.61

Expression of heme oxygenase-1 can determine cardiac xenograft survival. Nat Med (1998) 2.40

Genetic and immunological complexity of major histocompatibility regions. Science (1972) 2.40

Enhancement of antibody synthesis in vitro by mercaptoethanol. Cell Immunol (1972) 2.37

Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome. Lancet (1968) 2.29

Direct selective techniques for the isolation of pyrimidine auxotrophs in yeast. Mol Gen Genet (1972) 2.28

A20 blocks endothelial cell activation through a NF-kappaB-dependent mechanism. J Biol Chem (1996) 2.26

DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J Exp Med (1991) 2.14

Role of H-2 lymphocyte-defined and serologically-defined components in the generation of cytotoxic lymphocytes. J Exp Med (1974) 2.01

Transplantation of discordant xenografts: a review of progress. Immunol Today (1990) 2.00

A miniaturized mouse mixed leukocyte culture in serum-free and mouse serum supplemented media. J Immunol Methods (1973) 1.97

Lymphocyte reactivity in vitro. I. Cellular reconstitution of purified lymphocyte response. Cell Immunol (1970) 1.97

The major histocompatibility complex--genetics and biology. (First of three parts). N Engl J Med (1976) 1.92

HL-A LD (lymphocyte defined) typing: a rapid assay with primed lymphocytes. Science (1975) 1.91

Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants. J Immunol (2001) 1.89

Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens. Hum Immunol (1984) 1.83

Immunologic functions of isolated human lymphocyte subpopulations. III. Specific allogeneic lympholysis mediated by human T cells alone. J Immunol (1975) 1.83

Sequence polymorphism of HLA DR beta 1 alleles relating to T-cell-recognized determinants. Nature (1985) 1.82

Antigenic requirements for triggering of cytotoxic T lymphocytes. Immunol Rev (1977) 1.82

Phase I study of chimeric human/murine anti-ganglioside G(D2) monoclonal antibody (ch14.18) with granulocyte-macrophage colony-stimulating factor in children with neuroblastoma immediately after hematopoietic stem-cell transplantation: a Children's Cancer Group Study. J Clin Oncol (2000) 1.79

Lymphocyte reactivity in vitro. II. Soluble reconstituting factor permitting response of purified lymphocyte. Cell Immunol (1970) 1.74

Antigen-driven helper cell-independent cloned cytolytic T lymphocytes. Nature (1981) 1.72

Characterization of the interleukin 2 receptors (IL-2R) expressed on human natural killer cells activated in vivo by IL-2: association of the p64 IL-2R gamma chain with the IL-2R beta chain in functional intermediate-affinity IL-2R. J Exp Med (1992) 1.72

Allogeneic and xenogeneic response in mixed leukocyte cultures. J Exp Med (1972) 1.70

Five HLA-D clusters associated with HLA-DR4. Hum Immunol (1982) 1.70

Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2. Cancer Res (1990) 1.69

Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures. J Immunol (1987) 1.65

Generation of cytotoxic lymphocytes in vitro against autologous human leukaemia cells. Nature (1976) 1.64

A phase I/IB trial of murine monoclonal anti-GD2 antibody 14.G2a plus interleukin-2 in children with refractory neuroblastoma: a report of the Children's Cancer Group. Cancer (1997) 1.63

Loss of ATP diphosphohydrolase activity with endothelial cell activation. J Exp Med (1997) 1.62

Specificity of allogeneic cell recognition by human lymphocytes in vitro. Science (1971) 1.62

Cell kinetic studies in mixed leukocyte cultures: an in vitro model of homograft reactivity. Proc Natl Acad Sci U S A (1969) 1.61

Lymphocyte studies in congenital thymic dysplasia: The one-way stimulation test. J Pediatr (1968) 1.59

The molecular basis of alloreactivity. Immunol Today (1990) 1.56

Use of HLA loss mutants to analyse the structure of the human major histocompatibility complex. Nature (1982) 1.56

Mouse cell-mediated lympholysis assay in serum-free and mouse serum-supplemented media: culture conditions and genetic factors. Scand J Immunol (1975) 1.55

Genetic control of cell-mediated lympholysis in mouse. J Exp Med (1974) 1.51

TCGF production for cloning and growth of functional human T lymphocytes. Scand J Immunol (1980) 1.50

Severe combined immunodeficiency, interleukin-2 (IL-2), and the IL-2 receptor: experiments of nature continue to point the way. Blood (1994) 1.50

Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis. J Exp Med (1990) 1.50

Alternative pathways of T lymphocyte activation. J Exp Med (1978) 1.49

Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B. J Exp Med (1996) 1.49

Call for moratorium on xenotransplants. Nature (1998) 1.48

Specificity of antigen recognition by human lymphocytes in vitro. Science (1970) 1.48

Continuous culture of T cells cytotoxic for autologous human leukaemia cells. Nature (1979) 1.46

Recipient tumor necrosis factor-alpha and interleukin-10 gene polymorphisms associate with early mortality and acute graft-versus-host disease severity in HLA-matched sibling bone marrow transplants. Blood (1999) 1.46

Specificity in T cell mediated lympholysis: identical genetic control of the proliferative and effector phases of allogeneic and xenogeneic reactions. Transplant Rev (1976) 1.46

Lymphocyte reactivity to serologically undetected components of the major histocompatibility complex. Nat New Biol (1973) 1.44

Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation. Diabetes (2001) 1.43

Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury. FASEB J (2003) 1.42

Appropriate and necessary healthcare: new language for a new era. Am J Manag Care (1997) 1.42

Dw/LD-related molecular polymorphism of DR4 beta-chains. J Exp Med (1983) 1.42

Cooperative medical schemes in contemporary rural China. Soc Sci Med (1995) 1.42

Human mixed lymphocyte cultures. Evaluation of a microculture technique utilizing the Multiple Automated Sample Harvester (MASH). Clin Exp Immunol (1973) 1.41

Interferon-induced indoleamine 2,3-dioxygenase activity in human mononuclear phagocytes. J Leukoc Biol (1989) 1.41

Generation of cytotoxic T lymphocytes to autologous human leukaemia cells by sensitisation to pooled allogeneic normal cells. Nature (1978) 1.41