Published in J Biol Chem on October 25, 1982
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics (1996) 6.12
Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors. Proc Natl Acad Sci U S A (2001) 2.90
Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli. Proc Natl Acad Sci U S A (1991) 2.75
Kinetics of nitrosation of thiols by nitric oxide in the presence of oxygen. J Biol Chem (1995) 1.86
Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Annu Rev Physiol (1988) 1.82
Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. Proc Natl Acad Sci U S A (2001) 1.61
Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (1999) 1.60
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Serum myoglobin level as diagnostic test in patients with acute myocardial infarction. Br Heart J (1977) 1.32
Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450. Proc Natl Acad Sci U S A (1984) 1.30
Kinetics of nitric oxide autoxidation in aqueous solution. J Biol Chem (1994) 1.26
Substrate recognition sites in 14alpha-sterol demethylase from comparative analysis of amino acid sequences and X-ray structure of Mycobacterium tuberculosis CYP51. J Inorg Biochem (2001) 1.25
Transcriptional regulation of steroid hydroxylase genes by corticotropin. Proc Natl Acad Sci U S A (1986) 1.23
The role of cytochrome b5 in the biosynthesis of androgens by human P450c17. Arch Biochem Biophys (1995) 1.23
Spectral characterization of human hemoglobin and its derivatives. Methods Enzymol (1978) 1.21
Bovine adrenocortical cytochrome P-450(17 alpha). Regulation of gene expression by ACTH and elucidation of primary sequence. J Biol Chem (1986) 1.21
Diffusion coefficients of hemoglobin by intensity fluctuation spectroscopy: effects of varying pH and ionic strength. Biophys J (1981) 1.21
Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide. Proc Natl Acad Sci U S A (1985) 1.19
Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency. J Biol Chem (1993) 1.17
Interaction of sickle cell hemoglobin with erythrocyte membranes. Proc Natl Acad Sci U S A (1981) 1.17
Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development. Development (1994) 1.17
Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways. J Biol Chem (1998) 1.16
The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols. Arch Biochem Biophys (1996) 1.16
High-level expression of functional human cytochrome P450 1A2 in Escherichia coli. FASEB J (1992) 1.15
Rat haemoglobin heterogeneity. Two structurally distinct alpha chains and functional behaviour of selected components. Biochem J (1975) 1.15
Biochemical differences between rat and human cytochrome P450c17 support the different steroidogenic needs of these two species. Biochemistry (1999) 1.13
Biodiversity of CYP51 in trypanosomes. Biochem Soc Trans (2006) 1.12
Kinetics of nitric oxide dissociation from five- and six-coordinate nitrosyl hemes and heme proteins, including soluble guanylate cyclase. Biochemistry (1997) 1.11
Dissociation of nitric oxide from soluble guanylate cyclase. Biochem Biophys Res Commun (1997) 1.11
Basis of guanylate cyclase activation by carbon monoxide. Proc Natl Acad Sci U S A (1995) 1.10
Characterization of a stress-induced, developmentally regulated gene family from soybean. Plant Mol Biol (1992) 1.10
Expression, purification, and enzymatic properties of recombinant human cytochrome P450c27 (CYP27). Arch Biochem Biophys (1997) 1.08
Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex. Can J Biochem Cell Biol (1983) 1.07
Direct expression of adrenodoxin reductase in Escherichia coli and the functional characterization. Biol Pharm Bull (1993) 1.07
The hydrophobic amino-terminal sequence of bovine 17 alpha-hydroxylase is required for the expression of a functional hemoprotein in COS 1 cells. J Biol Chem (1991) 1.05
Effect of phenobarbital administration to rats on the level of the in vitro synthesis of cytochrome P-450 directed by total rat liver RNA. Biochem Biophys Res Commun (1979) 1.04
Methemoglobinemia from sniffing butyl nitrite. Ann Intern Med (1979) 1.04
Plasma and erythrocyte lipids in sickle cell anaemia. Clin Lab Haematol (1983) 1.03
NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase. Biochemistry (1998) 1.02
Identification by site-directed mutagenesis of two lysine residues in cholesterol side chain cleavage cytochrome P450 that are essential for adrenodoxin binding. J Biol Chem (1992) 1.01
Regulation of the biosynthesis of cytochromes P-450 involved in steroid hormone synthesis. Mol Cell Endocrinol (1985) 1.01
An additional electrostatic interaction between adrenodoxin and P450c27 (CYP27A1) results in tighter binding than between adrenodoxin and p450scc (CYP11A1). J Biol Chem (1999) 0.97
Myoglobinemia is an early and quantitative index of acute myocardial infarction. Angiology (1978) 0.97
Messenger RNAs encoding steroidogenic enzymes are expressed in rodent brain. Brain Res Mol Brain Res (1995) 0.97
Heterologous expression of mammalian P450 in COS cells. Methods Enzymol (1991) 0.97
A cAMP-regulatory sequence (CRS1) of CYP17 is a cellular target for the homeodomain protein Pbx1. J Biol Chem (1994) 0.96
Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP. Mol Endocrinol (1993) 0.96
Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP. J Biol Chem (1984) 0.96
Studies on the synthesis of sterol carrier protein-2 in rat adrenocortical cells in monolayer culture. Regulation by ACTH and dibutyryl cyclic 3',5'-AMP. J Biol Chem (1987) 0.95
Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo. Endocrinology (1995) 0.95
Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs. J Biol Chem (2001) 0.95
Induction of synthesis of cholesterol side chain cleavage cytochrome P-450 by adrenocorticotropin in cultured bovine adrenocortical cells. J Biol Chem (1981) 0.95
Kinetics and equilibria of soluble guanylate cyclase ligation by CO: effect of YC-1. Biochemistry (1999) 0.95
Nitric oxide inhibits methionine synthase activity in vivo and disrupts carbon flow through the folate pathway. J Biol Chem (2001) 0.95
No mutation in cytochrome P450 side chain cleavage in a patient with congenital lipoid adrenal hyperplasia. J Clin Endocrinol Metab (1994) 0.95
Acceleration of the rate of deoxyhemoglobin S polymerization by the erythrocyte membrane. FEBS Lett (1980) 0.95
Transcriptional regulation of the bovine CYP17 (P-450(17)alpha) gene. Identification of two cAMP regulatory regions lacking the consensus cAMP-responsive element (CRE). J Biol Chem (1990) 0.94
Effects of adrenocorticotropin on 17 alpha-hydroxylase activity and cytochrome P-450(17 alpha) synthesis in bovine adrenocortical cells. J Biol Chem (1985) 0.94
Regulation of steroid hydroxylase gene expression is multifactorial in nature. Recent Prog Horm Res (1989) 0.93
Members of the meis1 and pbx homeodomain protein families cooperatively bind a cAMP-responsive sequence (CRS1) from bovine CYP17. J Biol Chem (1998) 0.93
Angiotensin II inhibits luteinizing hormone-stimulated cholesterol side chain cleavage expression and stimulates basic fibroblast growth factor expression in bovine luteal cells in primary culture. J Biol Chem (1990) 0.93
Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells. Proc Natl Acad Sci U S A (1988) 0.93
Progesterone 16 alpha-hydroxylase activity is catalyzed by human cytochrome P450 17 alpha-hydroxylase. J Clin Endocrinol Metab (1993) 0.93
Protein synthesis inhibitors and ethanol selectively enhance heterologous expression of P450s and related proteins in Escherichia coli. Arch Biochem Biophys (1999) 0.92
Cyclic adenosine 3',5'-monophosphate(cAMP)/cAMP-responsive element modulator (CREM)-dependent regulation of cholesterogenic lanosterol 14alpha-demethylase (CYP51) in spermatids. Mol Endocrinol (1999) 0.92
Discriminatory processing of the precursor forms of cytochrome P-450scc and adrenodoxin by adrenocortical and heart mitochondria. J Biol Chem (1984) 0.92
P450(17 alpha) and P450SCC gene expression and regulation in the rat placenta. Endocrinology (1992) 0.92
Structural characterization of normal and mutant human steroid 17 alpha-hydroxylase genes: molecular basis of one example of combined 17 alpha-hydroxylase/17,20 lyase deficiency. Mol Endocrinol (1988) 0.92
The dissociation of NO from nitrosylhemoglobin. J Biol Chem (1978) 0.92
Geminate recombination of diatomic ligands CO, O2, and NO with myoglobin. Biochemistry (1994) 0.92
Tissue-specific and developmental regulation of cotton gene FbL2A. Demonstration of promoter activity in transgenic plants. Plant Physiol (1996) 0.92
A new mode for heme-heme interactions in hemoglobin associated with distal perturbations. Biophys J (1992) 0.91
Regulation of cytochrome P-45011 beta gene expression by adrenocorticotropin. J Biol Chem (1985) 0.91
Myoglobin-NO at low pH: free four-coordinated heme in the protein pocket. Biochemistry (1995) 0.91
Three zinc finger nuclear proteins, Sp1, Sp3, and a ZBP-89 homologue, bind to the cyclic adenosine monophosphate-responsive sequence of the bovine adrenodoxin gene and regulate transcription. Biochemistry (2000) 0.90
Cell-free synthesis of precursor forms of mitochondrial steroid hydroxylase enzymes of the bovine adrenal cortex. Arch Biochem Biophys (1982) 0.90
A new method for the determination of ligand dissociation rate constant of carboxyhemoglobin. Biochem Biophys Res Commun (1975) 0.90
Hemoglobin M equon beta 41 (C7) phenylalanine leads to tyrosine. Blood (1976) 0.89
Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a 7-basepair duplication in the N-terminal region of the cytochrome P45017 alpha (CYP17) gene. J Clin Endocrinol Metab (1990) 0.89
Two Sp1-binding sites mediate cAMP-induced transcription of the bovine CYP11A gene through the protein kinase A signaling pathway. J Biol Chem (1995) 0.89
Sympathoadrenal regulation of adrenocortical steroidogenesis. Endocr Res (1995) 0.88
Some enzymatic vagaries of a bovine adrenal microsomal cytochrome P-450 introduced and expressed in transformed monkey kidney cells. Prog Clin Biol Res (1988) 0.88
Sickle cell anemia and trait in a population of southern India. Am J Hematol (1977) 0.88
Identification of a common molecular basis for combined 17 alpha-hydroxylase/17,20-lyase deficiency in two Mennonite families. Hum Genet (1989) 0.88
Rat P450(17 alpha) from testis: characterization of a full-length cDNA encoding a unique steroid hydroxylase capable of catalyzing both delta 4- and delta 5-steroid-17,20-lyase reactions. Mol Endocrinol (1989) 0.88
Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells. Proc Natl Acad Sci U S A (1981) 0.88
Insights into the transcriptional regulation of steroidogenic enzymes and StAR. Rev Endocr Metab Disord (2001) 0.87
Negatively charged anabaena flavodoxin residues (Asp144 and Glu145) are important for reconstitution of cytochrome P450 17alpha-hydroxylase activity. J Biol Chem (1997) 0.87