Published in Drug Chem Toxicol on January 01, 1982
Effect of 4-vinylcyclohexene diepoxide dosing in rats on GSH levels in liver and ovaries. Toxicol Sci (2001) 2.51
A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies. Muscle Nerve (1997) 1.78
The time course for elevated muscle protein synthesis following heavy resistance exercise. Can J Appl Physiol (1995) 1.49
Muscle performance and enzymatic adaptations to sprint interval training. J Appl Physiol (1985) (1998) 1.46
Minimal biotransformation and toxicity of desflurane in guinea pig liver slices. Anesth Analg (1991) 1.39
Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats. Toxicol Appl Pharmacol (1996) 1.39
Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide. Reprod Toxicol (1995) 1.36
Elemental analysis of renal slices by proton-induced X-ray emission. Environ Health Perspect (1993) 1.35
Chicken FK506-binding protein, FKBP65, a member of the FKBP family of peptidylprolyl cis-trans isomerases, is only partially inhibited by FK506. Biochem J (1998) 1.33
Apoptosis induced in rats by 4-vinylcyclohexene diepoxide is associated with activation of the caspase cascades. Biol Reprod (2001) 1.28
Precision-cut tissue slices: applications in pharmacology and toxicology. Life Sci (1995) 1.27
Expression and redistribution of cellular Bad, Bax, and Bcl-X(L) protein is associated with VCD-induced ovotoxicity in rats. Biol Reprod (2001) 1.26
Ovotoxicity in female Fischer rats and B6 mice induced by low-dose exposure to three polycyclic aromatic hydrocarbons: comparison through calculation of an ovotoxic index. Toxicol Appl Pharmacol (2000) 1.21
Early effects of ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats and mice. Reprod Toxicol (1999) 1.18
The role of epoxidation in 4-vinylcyclohexene-induced ovarian toxicity. Toxicol Appl Pharmacol (1990) 1.18
Metabolism of 2,2',3,3',6,6'-hexachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl by human hepatic microsomes. Biochem Pharmacol (1983) 1.16
Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat. Toxicol Appl Pharmacol (1996) 1.15
Low-level arsenite causes accumulation of ubiquitinated proteins in rabbit renal cortical slices and HEK293 cells. Toxicol Appl Pharmacol (2003) 1.10
Effects on DNA integrity and apoptosis induction by a novel antitumor sesquiterpene drug, 6-hydroxymethylacylfulvene (HMAF, MGI 114). Biochem Pharmacol (1997) 1.07
Evaluation of certain food additives and contaminants. World Health Organ Tech Rep Ser (2007) 1.06
An animal model of hepatotoxicity associated with halothane anesthesia. Anesthesiology (1976) 1.06
Assessment of follicle destruction in chemical-induced ovarian toxicity. Annu Rev Pharmacol Toxicol (1996) 1.06
Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture. Toxicol Appl Pharmacol (2006) 1.03
An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. Anesthesiology (1979) 1.02
Vitamin A potentiation of carbon tetrachloride hepatotoxicity: role of liver macrophages and active oxygen species. Toxicol Appl Pharmacol (1993) 1.02
Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc (2000) 1.02
In vitro solubility and in vivo toxicity of gallium arsenide. Toxicol Appl Pharmacol (1984) 1.01
Chloroform toxicity in mice: correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules. Exp Mol Pathol (1973) 1.01
Metabolism of bisphenol a in primary cultured hepatocytes from mice, rats, and humans. Drug Metab Dispos (2002) 1.01
Dermal absorption of phthalate diesters in rats. Fundam Appl Toxicol (1989) 1.00
Safety assessment of allylalkoxybenzene derivatives used as flavouring substances - methyl eugenol and estragole. Food Chem Toxicol (2002) 1.00
Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: role of cytochrome P-450. Life Sci (1977) 1.00
Hypoxia and halothane metabolism in vivo: release of inorganic fluoride and halothane metabolite binding to cellular constituents. Anesthesiology (1976) 0.99
Cytotoxicity and genotoxicity of methyleugenol and related congeners-- a mechanism of activation for methyleugenol. Mutat Res (2000) 0.99
Drug uptake and cellular targets of hydroxymethylacylfulvene (HMAF). Biochem Pharmacol (1999) 0.99
Bioactivation and covalent binding of halothane in vitro: studies with [3H]- and [14C]halothane. J Pharmacol Exp Ther (1980) 0.98
Ovarian toxicity of 4-vinylcyclohexene diepoxide: a mechanistic model. Toxicol Pathol (2001) 0.97
The role of inflammatory cells and cytochrome P450 in the potentiation of CCl4-induced liver injury by a single dose of retinol. Toxicol Appl Pharmacol (1996) 0.97
Immortalized human urothelial cells as a model of arsenic-induced bladder cancer. Toxicology (2008) 0.96
Differential cytotoxicity and induction of apoptosis in tumor and normal cells by hydroxymethylacylfulvene (HMAF). Biochem Pharmacol (2000) 0.96
A single dose of the ovotoxicant 4-vinylcyclohexene diepoxide is protective in rat primary ovarian follicles. Toxicol Appl Pharmacol (1999) 0.96
Cisplatin nephrotoxicity: in vitro studies with precision-cut rabbit renal cortical slices. Toxicol Appl Pharmacol (1987) 0.96
Novel mechanisms in chemically induced hepatotoxicity. FASEB J (1994) 0.95
Circadian alterations in prolactin, corticosterone, and thyroid hormone levels and down-regulation of prolactin receptor activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (1987) 0.94
Human hepatic cytochrome P-450 composition as probed by in vitro microsomal metabolism of warfarin. Drug Metab Dispos (1984) 0.94
Comparison of the pharmacokinetics of several polychlorinated biphenyls in mouse, rat, dog, and monkey by means of a physiological pharmacokinetic model. Drug Metab Dispos (1985) 0.94
Preparation and composition of alveolar extracellular matrix and incorporated basement membrane. Lung (1981) 0.93
Comparison of the biotransformation and hepatotoxicity of halothane and deuterated halothane. J Pharmacol Exp Ther (1980) 0.93
Sodium arsenite enhances AP-1 and NFkappaB DNA binding and induces stress protein expression in precision-cut rat lung slices. Toxicol Sci (2001) 0.93
Pharmacokinetics of acrylamide in Fisher-344 rats. Toxicol Appl Pharmacol (1982) 0.92
Mechanisms of acute hepatic toxicity: chloroform, halothane, and glutathione. Anesthesiology (1974) 0.92
Characterization of the hepatic DNA damage caused by 1,2-dibromoethane using the alkaline elution technique. Carcinogenesis (1981) 0.91
Ovarian toxicity of 4-vinylcyclohexene and related olefins in B6C3F1 mice: role of diepoxides. Chem Res Toxicol (1996) 0.91
Risk assessment of chemical mixtures: biologic and toxicologic issues. Fundam Appl Toxicol (1993) 0.91
2,4,5,2',4',5'-Hexachlorobiphenyl: distribution, metabolism, and excretion in the dog and the monkey. Toxicol Appl Pharmacol (1982) 0.91
Toxicity and metabolism of subcytotoxic inorganic arsenic in human renal proximal tubule epithelial cells (HK-2). Cell Biol Toxicol (2003) 0.91
Plasma inorganic fluoride with sevoflurane anesthesia: correlation with indices of hepatic and renal function. Anesth Analg (1992) 0.90
Sensitive gas chromatographic determination of trifluoperazine in human plasma. J Chromatogr (1981) 0.90
Biotransformation and hepatotoxicity of halothane. Biochem Pharmacol (1977) 0.90
In vitro degradation of L-phenylalanine mustard (L-PAM). Cancer Chemother Pharmacol (1982) 0.90
Characterization of a halothane-induced humoral immune response in rabbits. Clin Exp Immunol (1987) 0.90
Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis. Molecular mimicry of trifluoroacetyl-lysine by lipoic acid. Eur J Biochem (1994) 0.90
Interdependent genotoxic mechanisms of monomethylarsonous acid: role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells. Toxicol Appl Pharmacol (2011) 0.89
Toxicokinetics of sulfasalazine (salicylazosulfapyridine) and its metabolites in B6C3F1 mice. Drug Metab Dispos (1994) 0.89
Myofibrillar disruption following acute concentric and eccentric resistance exercise in strength-trained men. Can J Physiol Pharmacol (2000) 0.89
Reactions of peroxynitrite with gamma-tocopherol. Chem Res Toxicol (1997) 0.88
A toxicologic and dermatologic assessment of linalool and related esters when used as fragrance ingredients. Food Chem Toxicol (2003) 0.88
Characterization of the disposition and toxicokinetics of N-butylpyridinium chloride in male F-344 rats and female B6C3F1 mice and its transport by organic cation transporter 2. Drug Metab Dispos (2009) 0.88
The acute hepatotoxicity of the isomers of dichlorobenzene in Fischer-344 and Sprague-Dawley rats: isomer-specific and strain-specific differential toxicity. Toxicol Appl Pharmacol (1991) 0.88
Some cardiovascular and autonomic effects of fenfluramine hydrochloride. J Pharmacol Exp Ther (1971) 0.87
Adaptation of a gamma-glutamyl transpeptidase assay to microtiter plates. Anal Biochem (1986) 0.87
Factors influencing halothane hepatotoxicity in the rat hypoxic model. Toxicol Appl Pharmacol (1980) 0.87
Culturing precision-cut human prostate slices as an in vitro model of prostate pathobiology. Cell Biol Toxicol (2002) 0.87
Preparation of positional renal slices for study of cell-specific toxicity. J Pharmacol Methods (1987) 0.87
Central nervous system effects of fenfluramine hydrochloride. J Pharmacol Exp Ther (1972) 0.87
Reduced ability of rat preantral ovarian follicles to metabolize 4-vinyl-1-cyclohexene diepoxide in vitro. Toxicol Appl Pharmacol (1994) 0.86
Precision cut tissue slices in culture: a new tool in pharmacology. Proc West Pharmacol Soc (1987) 0.86
Regulation of substance P by nerve growth factor: disruption by capsaicin. Brain Res (1982) 0.86
Halothane hepatotoxicity in guinea pigs. Anesth Analg (1987) 0.86
Purification and characterization of the dog hepatic cytochrome P-450 isozyme responsible for the metabolism of 2,2',4,4',5,5'-hexachlorobiphenyl. Arch Biochem Biophys (1987) 0.86
A rapid, sensitive method for quantifying enflurane in whole blood. Anesthesiology (1979) 0.85
Differential patterns of injury to the proximal tubule of renal cortical slices following in vitro exposure to mercuric chloride, potassium dichromate, or hypoxic conditions. Toxicol Appl Pharmacol (1987) 0.85
Dynamic organ culture of precision liver slices for in vitro toxicology. Life Sci (1985) 0.85
Follicular mechanisms associated with 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats. Reprod Toxicol (1996) 0.85
Lipid binding of a halothane metabolite. Relationship to lipid peroxidation in vitro. Drug Metab Dispos (1976) 0.85
Enhanced antitumor activity of 6-hydroxymethylacylfulvene in combination with irinotecan and 5-fluorouracil in the HT29 human colon tumor xenograft model. Cancer Res (1999) 0.85
Comparison of random and serial sections in assessment of ovarian toxicity. Reprod Toxicol (1991) 0.85
Hypothyroxinemia and hypothermia in rats in response to 2,3,7,8-tetrachlorodibenzo-p-dioxin administration. Toxicol Appl Pharmacol (1983) 0.85
Interleukin-8 (IL-8) over-production and autocrine cell activation are key factors in monomethylarsonous acid [MMA(III)]-induced malignant transformation of urothelial cells. Toxicol Appl Pharmacol (2011) 0.85
Long-term ovarian and gonadotropin changes in mice exposed to 4-vinylcyclohexene. Reprod Toxicol (1994) 0.85
Enhanced hepatic microsomal activity by pretreatment of rats with acetone or isopropanol. Proc Soc Exp Biol Med (1973) 0.84
The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies. Toxicology (2008) 0.84
Comparison of the disposition and in vitro metabolism of 4-vinylcyclohexene in the female mouse and rat. Toxicol Appl Pharmacol (1990) 0.84
Nature of the protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with dibenamine (N-(2-chloroethyl)dibenzylamine). Biochem Pharmacol (1974) 0.83
Cytotoxic effects of MGI 114 are independent of tumor p53 or p21 expression. Anticancer Res (1999) 0.83
Effects of dose and route on the disposition and kinetics of 1-butyl-1-methylpyrrolidinium chloride in male F-344 rats. Drug Metab Dispos (2009) 0.83